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The major objective of this paper is to examine the variations of injuries from road traffic accident in Lagos State. The study used mostly secondary data. The data where obtained for a period of thirty-two (32) years from 1970-2001. The 16 harmonies for the selected Local Government Areas considered contribute above 70% of the total variance in the time series. This means that more than 70% of injuries from road traffic accidents in Lagos State could be attributed to recklessness on the part of drivers, ignorance of high way codes, over speeding etc. Also, the dominant cycles of injuries from road traffic accidents observed in the study area have periodicities of 32.00 and 16.00 years with the most dominant being 32 years. Based on the findings, recommendations were proffered. [ABSTRACT FROM AUTHOR]