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This paper empirically identifies the factors driving Mexican immigration into the U.S. Great Plains region, focusing especially on the role of work in the Mexican and U.S. food-processing sectors, which in the context of NAFTA-induced foreign direct investments, opens up paths for migration along occupational lines into the U.S. from Mexico. Using a unique dataset on Mexican migration, the study addresses three related questions in a series of multivariate logistic regression analyses. First, is employment in the U.S. food-processing sector associated with Mexican migration into the Great Plains region? Second, does employment in the Mexican food-processing sector predict employment in the Great Plains food-processing sector? Finally, is the political-economic context linking Mexico and the U.S. related to the formation of occupational channels linking the food-processing sectors in Mexico and the U.S.? The findings demonstrate that the U.S. food-processing sector is a strong predictor of Mexican migration to the Great Plains region; Mexican migration is strongly channeled along occupational lines from Mexico to the U.S.; and the implementation of NAFTA, a period of intensive political-economic integration, strengthens the occupational channel between the food-processing sectors. [ABSTRACT FROM AUTHOR]