Search

Reaction of a quaternary ammonium salt with GaCl3 in concentrated HCl aqueous solution led to an organic–inorganic hybrid perovskite material [Me3NCMe3][GaCl4] (1), which shows a two-step off–on–off second harmonic generation (SHG) response with a rapid and large temperature interval. [ABSTRACT FROM AUTHOR]

Carborane compounds, known for their exceptional thermal stability and non‐toxic attributes, have garnered widespread utility in medicine, supramolecular design, coordination/organometallic chemistry, and others. Although there is considerable interest among chemists, the integration of suitable carborane molecules into ferroelectric materials remains a formidable challenge. In this study, we employ the quasi‐spherical design strategy to introduce functional groups at the boron vertices of the o‐carborane cage, aiming to reduce molecular symmetry. This approach led to the successful synthesis of the pioneering ferroelectric crystals composed of cage‐like carboranes: 9‐OH‐o‐carborane (1) and 9‐SH‐o‐carborane (2), which undergo above‐room ferroelectric phase transitions (Tc) at approximately 367 K and 347 K. Interestingly, 1 and 2 represent uniaxial and multiaxial ferroelectrics respectively, with 2 exhibiting six polar axes and as many as twelve equivalent polarization directions. As the pioneering instance of carborane ferroelectric crystals, this study introduces a novel structural archetype for molecular ferroelectrics, thereby providing fresh insights into the exploration of molecular ferroelectric crystals with promising applications. [ABSTRACT FROM AUTHOR]

Reported herein is an electrochemical strategy for N-sulfonylation of azoles with sulfonyl hydrazides, offering efficient access to valuable N-sulfonated azoles. Organic radical species were involved in the process and EPR experiments provided evidence for the formation of intermediates in situ. The electrochemical reaction features metal-free, mild conditions, and a broad substrate scope (>70 examples). The gram-scale synthesis via an electrochemical continuous-flow reaction and late-stage modification of complex compounds is advocated for its practical value. [ABSTRACT FROM AUTHOR]

Reported herein is a photochemical strategy for C(sp3)–H azolation of ethers via a hydrogen-atom transfer and radical-polar crossover process, offering efficient access to valuable N-alkylated azoles under visible-light irradiation. The protocol is metal-free and photocatalyst-free, and exhibits good to excellent yields and broad substrate scope with regard to azoles. EPR experiments provide evidence for the formation of intermediates formed in situ. [ABSTRACT FROM AUTHOR]

Organic ferroelectrics have received a great deal of interest due to their exclusive properties. However, organic ferroelectrics have not been fully explored, which hinders their practical application. Here, we presented a novel metal‐free organic molecular ferroelectric [4‐MCHA][ClO4] (1) (4‐MCHA=trans‐4‐methylcyclohexylamine), which exhibits an above‐room‐temperature of 328 K. Strikingly, the single crystal structure analysis of 1 shows that the driving force of phase transition is related to the interesting chair‐boat conformation change of 4‐MCHA cation, in addition to the order‐disorder transition of ClO4− anion. Using piezoelectric response force microscopy (PFM), the presence of domains and the implemented polarization switching were clearly observed, which explicitly determined the presence of room‐temperature ferroelectricity of 1. As far as we know, the ferroelectric phase transition mechanism attributed to the conformational change in a trans isomeric cation is very rare. This research enriched the path of designing ferroelectric materials and smart materials. [ABSTRACT FROM AUTHOR]

Solute Carrier Family 25 (SLC25) is the largest family of mitochondrial membrane proteins in the human body, consisting of 53 members. Mitochondrial phosphate carriers (MPiC), cellular iron metabolism, voltage-dependent anion channels (VDAC), and oxidative phosphorylation in the SLC25 family play dominant roles in material transport, energy metabolism, etc. SLC25 family-related proteins are involved in the regulation of the progression of a variety of cancers, including colon, gastric, and lung cancers. In addition, the SLC25 family has been implicated in endoplasmic reticulum stress (ERS) and immunity. Since SLC25 family proteins are involved in cancer progression and are associated with endoplasmic reticulum stress and immunity, exploring inhibitors of SLC25 family-related proteins is essential. However, the exact mechanism of SLC25 family-related proteins involved in cancer, as well as potential targets and SLC25 inhibitors have not been reported in the literature. This article focuses on summarizing the relevance of the SLC25 family to cancer, ERS, and immunity. This review also provides a comprehensive overview of SLC25 family-related inhibitors. [ABSTRACT FROM AUTHOR]

A novel solid-state second harmonic generation (SHG) organic–inorganic hybrid switch [Me3NCH2CH2F]FeBr4 (1) exhibits genuine three-step "on–off–on–off" SHG-switching above-room temperature, which has potential applications in multi-step optical devices. [ABSTRACT FROM AUTHOR]