228 results on '"Wang, Beilei"'
Search Results
2. A cofactor self-supplying and self-feedback DNAzyme nanodevice for cascade-amplified imaging of mRNA in living cells and in vivo
3. Molecular classification based on hypoxia-associated genes and construction of the prognostic model in Chronic Obstructive Pulmonary Disease
4. Brain-targeted nanoreactors prevent the development of organophosphate-induced delayed neurological damage
5. Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies
6. Discovery of IHMT-MST1-39 as a novel MST1 kinase inhibitor and AMPK activator for the treatment of diabetes mellitus
7. Nanoparticle accumulation in liver may induce resistance to immune checkpoint blockade therapy
8. Top-down Nanoscavengers for the protection of organophosphate-challenged cells
9. Discovery of dihydropyridinone derivative as a covalent EZH2 degrader
10. Discovery of Pyrazolo[1,5-a]pyrimidine derivative as a potent and selective PI3Kγ/δ dual inhibitor
11. Engineering of dendritic cell bispecific extracellular vesicles for tumor-targeting immunotherapy
12. Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
13. Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment
14. Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor
15. Oral feeding of nanoplastics affects brain function of mice by inducing macrophage IL-1 signal in the intestine
16. A Graph-guided Hybrid Regularization Method For Bioluminescence Tomography
17. Silk fibroin/chitosan coating with tunable catalytic nitric oxide generation for surface functionalization of cardiovascular stents
18. A real-time object tracking algorithm based on dual feature model kernel correlation filtering
19. LncRNA HOTTIP Knockdown Attenuates Acute Myocardial Infarction via Regulating miR-92a-2/c-Met Axis
20. Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
21. Carbazochrome attenuates acute lung injury in septic rats by inhibition of Parkin-mediated mitochondrial autophagy
22. Systemically administered silica nanoparticles result in diminished T cell response in lung
23. Discovery of Pyrazolo[1,5‑a]pyridine Derivatives as Potent and Selective PI3Kγ/δ Inhibitors.
24. Materials writing as a vehicle for teacher learning.
25. A review of methods for solving the optical molecular tomography.
26. Study of the applicability and optimal arrangement of alternative jet fans in curved road tunnel complexes
27. Study of smoke back-layering length with different longitudinal fire locations in inclined tunnels under natural ventilation
28. Investigating English Language Learners' Beliefs about Oral Corrective Feedback at Chinese Universities: A Large-Scale Survey
29. Discovery of (E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide (IHMT-TRK-284) as a novel orally available type II TRK kinase inhibitor capable of overcoming multiple resistant mutants
30. Multifunctional nanoparticles as photosensitizer delivery carriers for enhanced photodynamic cancer therapy
31. Study on the influence of bypass tunnel angle on gas shunting efficiency of urban road tunnels
32. An ultra-long circulating nanoparticle for reviving a highly selective BCR-ABL inhibitor in long-term effective and safe treatment of chronic myeloid leukemia
33. A Red-Emission Fluorescent Probe with Large Stokes Shift for Detection of Viscosity in Living Cells and Tumor-Bearing Mice.
34. Dynamic fluorescence molecular tomography metabolic parameters solution based on problem decomposition and prior refactor.
35. Insight into the dissolution behaviour and rheological characterisation of lignin in 1-butyl-3-methylimidazole bisulphate-ethanol system.
36. In vitro/in vivo evaluation of pH-sensitive Gambogenic acid loaded Zein nanoparticles with polydopamine coating
37. Discovery of 6′-chloro-N-methyl-5’-(phenylsulfonamido)-[3,3′-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium
38. Discovery of a novel and highly selective CDK9 kinase inhibitor (JSH-009) with potent antitumor efficacy in preclinical acute myeloid leukemia models
39. Preparation, Characterization, and In Vitro/In Vivo Evaluation of 3-O-β-D-Galactosylated Resveratrol-Loaded Polydopamine Nanoparticles
40. Study of the optimal pitch angle of jet fans in road tunnels based on turbulent jet theory and numerical simulation
41. Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
42. Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
43. Self-Feedback DNAzyme Motor for Cascade-Amplified Imaging of mRNA in Live Cells and In Vivo.
44. Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor
45. Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
46. Research on performance test analysis method of mechanical structure based on measured error / virtual simulation
47. An optimized phase-shifting algorithm for depth image acquisition
48. Image saliency detection for multiple objects
49. Low dose of emetine as potential anti-SARS-CoV-2 virus therapy: preclinical in vitro inhibition and in vivo pharmacokinetic evidences
50. Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC
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