224 results on '"Somers, Emily C."'
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2. Polybrominated biphenyls (PBBs) and prevalence of autoimmune disorders among members of the Michigan PBB registry
- Author
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Hood, Robert B., Terrell, Metrecia L., Mardovich, Sarah, Somers, Emily C., Pearson, Melanie, Barton, Hillary, Tomlinson, Martha Scott, Marder, M. Elizabeth, Barr, Dana Boyd, and Marcus, Michele
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- 2023
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3. Longitudinal antinuclear antibody titers in systemic lupus erythematosus and other rheumatic diseases.
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Littlejohn, Emily A., Lingxuan Kong, Lu Wang, and Somers, Emily C.
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- 2024
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4. Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases
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Robinson, Philip C., Bhana, Suleman, Liew, Jean W., Sufka, Paul H., Singh, Namrata, Howard, Richard A., Kim, Alfred H.J., Westrich-Robertson, Tiffany, Sirotich, Emily, Tsui, Edmund, Duarte-Garcia, Ali, Sparks, Jeffrey A., Tam, Herman, Jayatilleke, Arundathi, Konig, Maximilian F., Graef, Elizabeth R., Putman, Michael S., Syed, Reema H., Korsten, Peter, Mateus, Elsa, Sattui, Sebastian E., Wallace, Zachary S., Laura, Upton A., Adam, Kilian, Chock, Yu Pei Eugenia, White, Douglas W., Zamora, Geraldine T., Traboco, Lisa S., Patel, Aarat M., Grainger, Rebecca, Ugarte-Gil, Manuel F., Gianfrancesco, Milena A., Amigues, Isabelle, Sanchez-Alvarez, Catalina, Trupin, Laura, Jacobsohn, Lindsay R., Beesley, Richard P., Hoyer, Bimba F., Machado, Pedro M., Makan, Kavita, Gossec, Laure, Priyank, Chaudhary, Leipe, Jan, Wallace, Beth, Angeles-Han, Sheila T., Almaghlouth, Ibrahim A., Katherine, Wysham D., Padula, Anthony S., Berenbaum, Francis, Treemarcki, Erin M., Sinha, Rashmi, Lewandowski, Laura B., Webb, Kate, Young, Kristen J., Bulina, Inita, Herrera Uribe, Sebastian, Rubinstein, Tamar B., Nolan, Marc W., Ang, Elizabeth Y., Venuturupalli, Swamy R., Hausmann, Jonathan S., Dubreuil, Maureen, Pisoni, Cecilia N., Cosatti, Micaela A., Campos, Jose, Simard, Julia F., Conway, Richard, Peterson, Tiffany M., Harrison, Carly O., Felix, Christele, Richards, Dawn P., Proulx, Laurie, Akpabio, Akpabio A., Worthing, Angus B., Laidlaw, Lynn R., Reid, Pankti, Palmerlee, Candace A., Danila, Maria I., Sahar, Lotfi-Emran, Linh, Ngo Q., Agarwal, Arnav, Studenic, Paul, Liew, David F.L., Larche, Maggie J., Mingolla, Serena A.M., Zamora, Erick A., Angevare, Saskya S., Sinha, Rashmi R., Durrant, Karen L.W., Peirce, Andrea, Somers, Emily C., Cappelli, Laura C., Frankel, Brittany A., Kumar, Bharat, Silinsky Krupnikova, Sonia D., Rosario Vega, Jorge A., Frankovich, Jourdan, Fernandez-Ruiz, Ruth, Posada Velásquez, Marcela, Yeoh, Su-Ann, Marino, Maria, Nudel, Michal, Scott, Chrisiaan, Rodríguez, Cecilia, Martín Mancheño, Ana I., Seo, Philip, Gamboa-Cárdenas, Rocío V., Pimentel-Quiroz, Victor R., Reátegui-Sokolova, Cristina, Kihara, Mari, Lin, Chung M.A., Kattula, Dheera, Laila, Girgis, Carmona, Loreto, Wallace, John, Yazdany, Jinoos, Costello, Wendy, Gore-massy, Monique C., Tomasella, Laura-Ann, Kodek, Moré A., Hausmann, Jonathan S, Kennedy, Kevin, Simard, Julia F, Liew, Jean W, Sparks, Jeffrey A, Moni, Tarin T, Harrison, Carly, Larché, Maggie J, Levine, Mitchell, Sattui, Sebastian E, Semalulu, Teresa, Foster, Gary, Surangiwala, Salman, Thabane, Lehana, Beesley, Richard P, Durrant, Karen L, Mateus, Elsa F, Mingolla, Serena, Palmerlee, Candace A, Richards, Dawn P, Liew, David F L, Hill, Catherine L, Machado, Pedro M, Robinson, Philip C, Sufka, Paul, and Wallace, Zachary S
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- 2021
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5. Prescription Opioid Use in Patients With and Without Systemic Lupus Erythematosus — Michigan Lupus Epidemiology and Surveillance Program, 2014–2015
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Somers, Emily C., Lee, Jiha, Hassett, Afton L., Zick, Suzanna M., Harlow, Siobán D., Helmick, Charles G., Barbour, Kamil E., Gordon, Caroline, Brummett, Chad M., Minhas, Deeba, Padda, Amrita, Wang, Lu, McCune, W. Joseph, and Marder, Wendy
- Published
- 2019
6. Contributors
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Ahearn, Joseph M., primary, Alarcón-Riquelme, Marta E., additional, Almaani, Salem J., additional, Anolik, Jennifer H., additional, Aranow, Cynthia, additional, Bacalao, Maria A., additional, Barilla-LaBarca, Maria-Louise, additional, Barnas, Jennifer L., additional, Barturen, Guillermo, additional, Bermas, Bonnie L., additional, Bernatsky, Sasha, additional, Bruce, I.N., additional, Bucala, Richard, additional, Buyon, Jill P., additional, Carnero-Montoro, Elena, additional, Clarke, Ann E., additional, Clowse, Megan E.B., additional, Concha, Josef Symon S., additional, Dellaripa, Paul, additional, Diamond, Betty, additional, Doyle, Tracy J., additional, Fernando, Michelle M.A., additional, Fisk, John D., additional, Furie, Richard, additional, Gordon, Caroline, additional, Greiling, Teri M., additional, Han, Shuhong, additional, Hanly, John G., additional, Hile, Grace A., additional, Horowitz, Diane, additional, Isenberg, David, additional, Izmirly, Peter, additional, Jacobs, Barbara, additional, James, Judith A., additional, Kahlenberg, J. Michelle, additional, Kalunian, Kenneth C., additional, Kang, Insoo, additional, Kaplan, Mariana J., additional, Khamashta, Munther A., additional, Kim, Mimi, additional, Knight, Jason S., additional, Koumpouras, Fotios, additional, Kriegel, Martin A., additional, La Cava, Antonio, additional, Ladouceur, Alexandra, additional, Lahita, Robert G., additional, Lee, Iris Jung-Won, additional, Lessard, Christopher J., additional, Lewandowski, Laura B., additional, Liang, Yun, additional, Liu, Chau-Ching, additional, Mackay, Meggan, additional, Madaio, Michael P., additional, Marder, Galina, additional, Matteson, Eric L., additional, McCoy, Sara, additional, McMahon, Maureen, additional, Meffre, Eric, additional, Mejia-Vilet, Juan, additional, Merrill, Joan, additional, Morand, Eric F., additional, Moreira Pinto, Sara, additional, Nakabo, Shuichiro, additional, Northcott, Melissa, additional, Omisade, Antonina, additional, Ortel, Thomas L., additional, Perl, Andras, additional, Ramsey-Goldman, Rosalind, additional, Reeves, Westley H., additional, Reyes-Thomas, Joyce, additional, Reynolds, J.A., additional, Richardson, Bruce, additional, Rodriguez, Juan Vicente, additional, Rovin, Brad H., additional, Rudinskaya, Alla, additional, Ruiz-Irastorza, Guillermo, additional, Saxena, Amit, additional, Schanberg, Laura E., additional, Sharma, Tarun S., additional, Skaggs, Brian, additional, Somers, Emily C., additional, Stohl, William, additional, Talabi, Mehret Birru, additional, Tessneer, Kandice L., additional, Tsao, Betty P., additional, Ugarte, Amaia, additional, Volpe, Bruce T., additional, Vyse, Timothy J., additional, Wainwright, Benjamin J., additional, Ward, Michael M., additional, Wasko, Mary Chester M., additional, Werth, Victoria P., additional, Wise, Leanna, additional, Zhuang, Haoyang, additional, and Zuo, Yu, additional
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- 2021
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7. Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
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Kartsonaki, Christiana, Baillie, J Kenneth, Barrio, Noelia García, Baruch, Joaquín, Beane, Abigail, Blumberg, Lucille, Bozza, Fernando, Broadley, Tessa, Burrell, Aidan, Carson, Gail, Citarella, Barbara Wanjiru, Dagens, Andrew, Dankwa, Emmanuelle A, Donnelly, Christl A, Dunning, Jake, Elotmani, Loubna, Escher, Martina, Farshait, Nataly, Goffard, Jean-Christophe, Gonçalves, Bronner P, Hall, Matthew, Hashmi, Madiha, Sim Lim Heng, Benedict, Ho, Antonia, Jassat, Waasila, Pedrera Jiménez, Miguel, Laouenan, Cedric, Lissauer, Samantha, Martin-Loeches, Ignacio, Mentré, France, Merson, Laura, Morton, Ben, Munblit, Daniel, Nekliudov, Nikita A, Nichol, Alistair D, Singh Oinam, Budha Charan, Ong, David, Panda, Prasan Kumar, Petrovic, Michele, Pritchard, Mark G, Ramakrishnan, Nagarajan, Ramos, Grazielle Viana, Roger, Claire, Sandulescu, Oana, Semple, Malcolm G, Sharma, Pratima, Sigfrid, Louise, Somers, Emily C, Streinu-Cercel, Anca, Taccone, Fabio, Vecham, Pavan Kumar, Kumar Tirupakuzhi Vijayaraghavan, Bharath, Wei, Jia, Wils, Evert-Jan, Ci Wong, Xin, Horby, Peter, Rojek, Amanda, Olliaro, Piero L, ISARIC Clinical Characterisation Group: Ali Abbas, Sheryl Ann Abdukahil, Nurul Najmee Abdulkadir, Ryuzo Abe, Laurent Abel, Lara Absil, Subhash Acharya, Andrew Acker, Elisabeth Adam, Diana Adrião, Saleh Al Ageel, Shakeel Ahmed, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Eman Al Qasim, Razi Alalqam, Angela Alberti, Tala Al-Dabbous, Senthilkumar Alegesan, Cynthia Alegre, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Huda Alfoudri, Imran Ali, Adam Ali, Naseem Ali Shah, Kazali Enagnon Alidjnou, Jeffrey Aliudin, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Aneela Altaf, João Alves, Rita Alves, João Melo Alves, Maria Amaral, Nur Amira, Phoebe Ampaw, Roberto Andini, Claire Andréjak, Andrea Angheben, François Angoulvant, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Angel Asensio, Muhammad Ashraf, Namra Asif, Mohammad Asim, Jean Baptiste Assie, Amirul Asyraf, Anika Atique, A M Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Laurène Azemar, Cecile Azoulay, Benjamin Bach, Delphine Bachelet, Claudine Badr, Nadia Baig, J Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Andriy Bal, Mohanaprasanth Balakrishnan, Valeria Balan, Firouzé Bani-Sadr, Renata Barbalho, Nicholas Yuri Barbosa, Wendy S Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Audrey Barrelet, Cleide Barrigoto, Marie Bartoli, Mustehan Bashir, Romain Basmaci, Muhammad Fadhli Hassin Basri, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Sylvie Behilill, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Dehbia Benkerrou, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Delphine Bergeaud, Hazel Bergin, José Luis Bernal Sobrino, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Krishna Bhavsar, Claudia Bianco, Farah Nadiah Bidin, Moirangthem Bikram Singh, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, François Bissuel, Patrick Biston, Laurent Bitker, Jonathan Bitton, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Filomena Boccia, Laetitia Bodenes, Alice Bogaarts, Debby Bogaert, Anne-Hélène Boivin, Pierre-Adrien Bolze, François Bompart, Aurelius Bonfasius, Diogo Borges, Raphaël Borie, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Dounia Bouhmani, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Jason Bouziotis, Bianca Boxma, Marielle Boyer-Besseyre, Maria Boylan, Axelle Braconnier, Cynthia Braga, Timo Brandenburger, Filipa Brás Monteiro, Luca Brazzi, Patrick Breen, Dorothy Breen, Kathy Brickell, Shaunagh Browne, Alex Browne, Nicolas Brozzi, Marjolein Brusse-Keizer, Nina Buchtele, Christian Buesaquillo, Polina Bugaeva, Marielle Buisson, Danilo Buonsenso, Erlina Burhan, Ingrid G Bustos, Denis Butnaru, André Cabie, Susana Cabral, Eder Caceres, Cyril Cadoz, Mia Callahan, Kate Calligy, Jose Andres Calvache, João Camões, Valentine Campana, Paul Campbell, Josie Campisi, Cecilia Canepa, Mireia Cantero, Pauline Caraux-Paz, Sheila Cárcel, Chiara Simona Cardellino, Sofia Cardoso, Filipe Cardoso, Filipa Cardoso, Nelson Cardoso, Simone Carelli, Nicolas Carlier, Thierry Carmoi, Gayle Carney, Inês Carqueja, Marie-Christine Carret, François Martin Carrier, Ida Carroll, Maire-Laure Casanova, Mariana Cascão, Siobhan Casey, José Casimiro, Bailey Cassandra, Silvia Castañeda, Nidyanara Castanheira, Guylaine Castor-Alexandre, Henry Castrillón, Ivo Castro, Ana Catarino, François-Xavier Catherine, Paolo Cattaneo, Roberta Cavalin, Giulio Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Minerva Cervantes-Gonzalez, Anissa Chair, Catherine Chakveatze, Adrienne Chan, Meera Chand, Christelle Chantalat Auger, Jean-Marc Chapplain, Julie Chas, Allegra Chatterjee, Mobin Chaudry, Jonathan Samuel Chávez Iñiguez, Anjellica Chen, Yih-Sharng Chen, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Suresh Kumar Chidambaram, Leong Chin Tho, Catherine Chirouze, Davide Chiumello, Sung-Min Cho, Bernard Cholley, Marie-Charlotte Chopin, Ting Soo Chow, Yock Ping Chow, Hiu Jian Chua, Jonathan Chua, Jose Pedro Cidade, José Miguel Cisneros Herreros, Anna Ciullo, Jennifer Clarke, Emma Clarke, Rolando Claure-Del Granado, Sara Clohisey, Perren J Cobb, Cassidy Codan, Caitriona Cody, Alexandra Coelho, Megan Coles, Gwenhaël Colin, Michael Collins, Sebastiano Maria Colombo, Pamela Combs, Marie Connor, Anne Conrad, Sofía Contreras, Elaine Conway, Graham S Cooke, Mary Copland, Hugues Cordel, Amanda Corley, Sabine Cornelis, Alexander Daniel Cornet, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Emma Costigan, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Rachel Cregan, Charles Crepy D'Orleans, Cosimo Cristella, Sabine Croonen, Gloria Crowl, Jonathan Crump, Claudina Cruz, Juan Luis Cruz Berm, Jaime Cruz Rojo, Marc Csete, Ailbhe Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Colleen Curran, Paula Custodio, Ana da Silva Filipe, Charlene Da Silveira, Al-Awwab Dabaliz, Darren Dahly, Heidi Dalton, Jo Dalton, Seamus Daly, Nick Daneman, Corinne Daniel, Jorge Dantas, Frédérick D'Aragon, Menno de Jong, Gillian de Loughry, Diego de Mendoza, Etienne De Montmollin, Rafael Freitas de Oliveira França, Ana Isabel de Pinho Oliveira, Rosanna De Rosa, Cristina De Rose, Thushan de Silva, Peter de Vries, Jillian Deacon, David Dean, Alexa Debard, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Lauren Deconninck, Romain Decours, Eve Defous, Isabelle Delacroix, Eric Delaveuve, Karen Delavigne, Nathalie M Delfos, Ionna Deligiannis, Andrea Dell'Amore, Christelle Delmas, Pierre Delobel, Corine Delsing, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Mehul Desai, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhanger, Alpha Diallo, Sylvain Diamantis, André Dias, Juan Jose Diaz, Priscila Diaz, Rodrigo Diaz, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Fara Diop, Alphonsine Diouf, Yael Dishon, Félix Djossou, Annemarie B Docherty, Helen Doherty, Arjen M Dondorp, Andy Dong, Maria Donnelly, Sean Donohue, Yoann Donohue, Chloe Donohue, Peter Doran, Céline Dorival, Eric D'Ortenzio, James Joshua Douglas, Renee Douma, Nathalie Dournon, Triona Downer, Joanne Downey, Mark Downing, Tom Drake, Aoife Driscoll, Murray Dryden, Claudio Duarte Fonseca, Vincent Dubee, François Dubos, Alexandre Ducancelle, Toni Duculan, Susanne Dudman, Abhijit Duggal, Paul Dunand, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham, Bertrand Dussol, Juliette Duthoit, Xavier Duval, Anne Margarita Dyrhol-Riise, Sim Choon Ean, Marco Echeverria-Villalobos, Siobhan Egan, Carla Eira, Mohammed El Sanharawi, Subbarao Elapavaluru, Brigitte Elharrar, Jacobien Ellerbroek, Philippine Eloy, Tarek Elshazly, Iqbal Elyazar, Isabelle Enderle, Tomoyuki Endo, Chan Chee Eng, Ilka Engelmann, Vincent Enouf, Olivier Epaulard, Mariano Esperatti, Hélène Esperou, Marina Esposito-Farese, João Estevão, Manuel Etienne, Nadia Ettalhaoui, Anna Greti Everding, Mirjam Evers, Marc Fabre, Isabelle Fabre, Amna Faheem, Arabella Fahy, Cameron J Fairfield, Zul Fakar, Komal Fareed, Pedro Faria, Ahmed Farooq, Hanan Fateena, Arie Zainul Fatoni, Karine Faure, Raphaël Favory, Mohamed Fayed, Niamh Feely, Laura Feeney, Jorge Fernandes, Marília Andreia Fernandes, Susana Fernandes, François-Xavier Ferrand, Eglantine Ferrand Devouge, Joana Ferrão, Mário Ferraz, Sílvia Ferreira, Isabel Ferreira, Benigno Ferreira, Ricard Ferrer-Roca, Nicolas Ferriere, Céline Ficko, Claudia Figueiredo-Mello, William Finlayson, Juan Fiorda, Thomas Flament, Clara Flateau, Tom Fletcher, Letizia Lucia Florio, Deirdre Flynn, Claire Foley, Jean Foley, Victor Fomin, Tatiana Fonseca, Patricia Fontela, Simon Forsyth, Denise Foster, Giuseppe Foti, Erwan Fourn, Robert A Fowler, Marianne Fraher, Diego Franch-Llasat, John F Fraser, Christophe Fraser, Marcela Vieira Freire, Ana Freitas Ribeiro, Caren Friedrich, Ricardo Fritz, Stéphanie Fry, Nora Fuentes, Masahiro Fukuda, G Argin, Valérie Gaborieau, Rostane Gaci, Massimo Gagliardi, Jean-Charles Gagnard, Amandine Gagneux-Brunon, Sérgio Gaião, Linda Gail Skeie, Phil Gallagher, Carrol Gamble, Yasmin Gani, Arthur Garan, Rebekha Garcia, Julia Garcia-Diaz, Esteban Garcia-Gallo, Navya Garimella, Denis Garot, Valérie Garrait, Basanta Gauli, Nathalie Gault, Aisling Gavin, Anatoliy Gavrylov, Alexandre Gaymard, Johannes Gebauer, Eva Geraud, Louis Gerbaud Morlaes, Nuno Germano, Praveen Kumar Ghisulal, Jade Ghosn, Marco Giani, Jess Gibson, Tristan Gigante, Morgane Gilg, Elaine Gilroy, Guillermo Giordano, Michelle Girvan, Valérie Gissot, Daniel Glikman, Petr Glybochko, Eric Gnall, Geraldine Goco, François Goehringer, Siri Goepel, Jin Yi Goh, Jonathan Golob, Rui Gomes, Kyle Gomez, Joan Gómez-Junyent, Marie Gominet, Alicia Gonzalez, Patricia Gordon, Isabelle Gorenne, Laure Goubert, Cécile Goujard, Tiphaine Goulenok, Margarite Grable, Jeronimo Graf, Edward Wilson Grandin, Pascal Granier, Giacomo Grasselli, Christopher A Green, Courtney Greene, William Greenhalf, Segolène Greffe, Domenico Luca Grieco, Matthew Griffee, Fiona Griffiths, Ioana Grigoras, Albert Groenendijk, Anja Grosse Lordemann, Heidi Gruner, Yusing Gu, Jérémie Guedj, Martin Guego, Dewi Guellec, Anne-Marie Guerguerian, Daniela Guerreiro, Romain Guery, Anne Guillaumot, Laurent Guilleminault, Maisa Guimarães de Castro, Thomas Guimard, Marieke Haalboom, Daniel Haber, Hannah Habraken, Ali Hachemi, Amy Hackmann, Nadir Hadri, Fakhir Haidri, Sheeba Hakak, Adam Hall, Sophie Halpin, Jawad Hameed, Ansley Hamer, Raph L Hamers, Rebecca Hamidfar, Terese Hammond, Lim Yuen Han, Rashan Haniffa, Kok Wei Hao, Hayley Hardwick, Ewen M Harrison, Janet Harrison, Samuel Bernard Ekow Harrison, Alan Hartman, Mohd Shahnaz Hasan, Junaid Hashmi, Muhammad Hayat, Ailbhe Hayes, Leanne Hays, Jan Heerman, Lars Heggelund, Ross Hendry, Martina Hennessy, Aquiles Henriquez-Trujillo, Maxime Hentzien, Jaime Hernandez-Montfort, Andrew Hershey, Liv Hesstvedt, Astarini Hidayah, Eibhilin Higgins, Dawn Higgins, Rupert Higgins, Rita Hinchion, Samuel Hinton, Hiroaki Hiraiwa, Haider Hirkani, Hikombo Hitoto, Yi Bin Ho, Alexandre Hoctin, Isabelle Hoffmann, Wei Han Hoh, Oscar Hoiting, Rebecca Holt, Jan Cato Holter, Juan Pablo Horcajada, Koji Hoshino, Ikram Houas, Catherine L Hough, Stuart Houltham, Jimmy Ming-Yang Hsu, Jean-Sébastien Hulot, Stella Huo, Abby Hurd, Iqbal Hussain, Samreen Ijaz, Hajnal-Gabriela Illes, Patrick Imbert, Mohammad Imran, Rana Imran Sikander, Aftab Imtiaz, Hugo Inácio, Carmen Infante Dominguez, Yun Sii Ing, Elias Iosifidis, Mariachiara Ippolito, Sarah Isgett, Tiago Isidoro, Nadiah Ismail, Margaux Isnard, Junji Itai, Daniel Ivulich, Danielle Jaafar, Salma Jaafoura, Julien Jabot, Clare Jackson, Nina Jamieson, Victoria Janes, Pierre Jaquet, Coline Jaud-Fischer, Stéphane Jaureguiberry, Jeffrey Javidfar, Denise Jaworsky, Florence Jego, Anilawati Mat Jelani, Synne Jenum, Ruth Jimbo-Sotomayor, Ong Yiaw Joe, Ruth N Jorge García, Cédric Joseph, Mark Joseph, Swosti Joshi, Mercé Jourdain, Philippe Jouvet, Hanna Jung, Anna Jung, Dafsah Juzar, Ouifiya Kafif, Florentia Kaguelidou, Neerusha Kaisbain, Thavamany Kaleesvran, Sabina Kali, Alina Kalicinska, Smaragdi Kalomoiri, Muhammad Aisar Ayadi Kamaluddin, Zul Amali Che Kamaruddin, Nadiah Kamarudin, Paul Kambiya, Kavita Kamineni, Darshana Hewa Kandamby, Chris Kandel, Kong Yeow Kang, Darakhshan Kanwal, Pratap Karpayah, Todd Karsies, Daisuke Kasugai, Anant Kataria, Kevin Katz, Aasmine Kaur, Christy Kay, Hannah Keane, Seán Keating, Pulak Kedia, Claire Kelly, Yvelynne Kelly, Andrea Kelly, Niamh Kelly, Aoife Kelly, Sadie Kelly, Maeve Kelsey, Ryan Kennedy, Kalynn Kennon, Maeve Kernan, Younes Kerroumi, Sharma Keshav, Imrana Khalid, Osama Khalid, Antoine Khalil, Coralie Khan, Irfan Khan, Quratul Ain Khan, Sushil Khanal, Abid Khatak, Amin Khawaja, Krish Kherajani, Michelle E Kho, Saye Khoo, Ryan Khoo, Denisa Khoo, Nasir Khoso, Khor How Kiat, Yuri Kida, Peter Kiiza, Beathe Kiland Granerud, Anders Benjamin Kildal, Jae Burm Kim, Antoine Kimmoun, Detlef Kindgen-Milles, Alexander King, Nobuya Kitamura, Paul Klenerman, Rob Klont, Gry Kloumann Bekken, Stephen R Knight, Robin Kobbe, Chamira Kodippily, Malte Kohns Vasconcelos, Sabin Koirala, Mamoru Komatsu, Caroline Kosgei, Arsène Kpangon, Karolina Krawczyk, Vinothini Krishnan, Sudhir Krishnan, Oksana Kruglova, Deepali Kumar, Ganesh Kumar, Mukesh Kumar, Dinesh Kuriakose, Ethan Kurtzman, Demetrios Kutsogiannis, Galyna Kutsyna, Konstantinos Kyriakoulis, Marie Lachatre, Marie Lacoste, John G Laffey, Marie Lagrange, Fabrice Laine, Olivier Lairez, Sanjay Lakhey, Antonio Lalueza, Marc Lambert, François Lamontagne, Marie Langelot-Richard, Vincent Langlois, Eka Yudha Lantang, Marina Lanza, Cédric Laouénan, Samira Laribi, Delphine Lariviere, Stéphane Lasry, Sakshi Lath, Naveed Latif, Odile Launay, Didier Laureillard, Yoan Lavie-Badie, Andy Law, Teresa Lawrence, Cassie Lawrence, Minh Le, Clément Le Bihan, Cyril Le Bris, Georges Le Falher, Lucie Le Fevre, Quentin Le Hingrat, Marion Le Maréchal, Soizic Le Mestre, Gwenaël Le Moal, Vincent Le Moing, Hervé Le Nagard, Paul Le Turnier, Ema Leal, Marta Leal Santos, Todd C Lee, James Lee, Jennifer Lee, Heng Gee Lee, Biing Horng Lee, Yi Lin Lee, Su Hwan Lee, Gary Leeming, Laurent Lefebvre, Bénédicte Lefebvre, Benjamin Lefevre, Sylvie LeGac, Jean-Daniel Lelievre, François Lellouche, Adrien Lemaignen, Véronique Lemee, Anthony Lemeur, Gretchen Lemmink, Ha Sha Lene, Jenny Lennon, Rafael León, Marc Leone, Michela Leone, Quentin Lepiller, François-Xavier Lescure, Olivier Lesens, Mathieu Lesouhaitier, Amy Lester-Grant, Bruno Levy, Yves Levy, Claire Levy-Marchal, Katarzyna Lewandowska, Erwan L'Her, Gianluigi Li Bassi, Janet Liang, Ali Liaquat, Geoffrey Liegeon, Wei Shen Lim, Kah Chuan Lim, Chantre Lima, Lim Lina, Bruno Lina, Andreas Lind, Maja Katherine Lingad, Guillaume Lingas, Sylvie Lion-Daolio, Keibun Liu, Marine Livrozet, Patricia Lizotte, Antonio Loforte, Navy Lolong, Leong Chee Loon, Diogo Lopes, Dalia Lopez-Colon, Jose W Lopez-Revilla, Anthony L Loschner, Paul Loubet, Bouchra Loufti, Guillame Louis, Silvia Lourenco, Lara Lovelace-Macon, Lee Lee Low, Marije Lowik, Jia Shyi Loy, Jean Christophe Lucet, Carlos Lumbreras Bermejo, Carlos M Luna, Olguta Lungu, Liem Luong, Nestor Luque, Dominique Luton, Nilar Lwin, Ruth Lyons, Olavi Maasikas, Oryane Mabiala, Moïse Machado, Gabriel Macheda, Hashmi Madiha, Guillermo Maestro de la Calle, Rafael Mahieu, Sophie Mahy, Ana Raquel Maia, Lars S Maier, Mylène Maillet, Thomas Maitre, Maximilian Malfertheiner, Nadia Malik, Paddy Mallon, Fernando Maltez, Denis Malvy, Victoria Manda, Laurent Mandelbrot, Frank Manetta, Julie Mankikian, Edmund Manning, Aldric Manuel, Ceila Maria Sant Ana Malaque, Flávio Marino, Daniel Marino, Samuel Markowicz, Charbel Maroun Eid, Ana Marques, Catherine Marquis, Brian Marsh, Laura Marsh, Megan Marshal, John Marshall, Celina Turchi Martelli, Dori-Ann Martin, Emily Martin, Guillaume Martin-Blondel, Martin Martinot, Alejandro Martin-Quiros, João Martins, Ana Martins, Nuno Martins, Caroline Martins Rego, Gennaro Martucci, Olga Martynenko, Eva Miranda Marwali, Marsilla Marzukie, David Maslove, Sabina Mason, Sobia Masood, Basri Mat Nor, Moshe Matan, Meghena Mathew, Daniel Mathieu, Mathieu Mattei, Romans Matulevics, Laurence Maulin, Michael Maxwell, Javier Maynar, Thierry Mazzoni, Natalie Mc Evoy, Lisa Mc Sweeney, Colin McArthur, Anne McCarthy, Aine McCarthy, Colin McCloskey, Rachael McConnochie, Sherry McDermott, Sarah E McDonald, Aine McElroy, Samuel McElwee, Victoria McEneany, Allison McGeer, Chris McKay, Johnny McKeown, Kenneth A McLean, Paul McNally, Bairbre McNicholas, Elaine McPartlan, Edel Meaney, Cécile Mear-Passard, Maggie Mechlin, Maqsood Meher, Omar Mehkri, Ferruccio Mele, Luis Melo, Kashif Memon, Joao Joao Mendes, Ogechukwu Menkiti, Kusum Menon, Alexander J Mentzer, Emmanuelle Mercier, Noémie Mercier, Antoine Merckx, Mayka Mergeay-Fabre, Blake Mergler, António Mesquita, Roberta Meta, Osama Metwally, Agnès Meybeck, Dan Meyer, Alison M Meynert, Vanina Meysonnier, Amina Meziane, Mehdi Mezidi, Céline Michelanglei, Isabelle Michelet, Efstathia Mihelis, Vladislav Mihnovit, Hugo Miranda-Maldonado, Nor Arisah Misnan, Tahira Jamal Mohamed, Nik Nur Eliza Mohamed, Asma Moin, David Molina, Elena Molinos, Brenda Molloy, Mary Mone, Agostinho Monteiro, Claudia Montes, Giorgia Montrucchio, Shona C Moore, Sarah Moore, Lina Morales Cely, Lucia Moro, Catherine Motherway, Ana Motos, Hugo Mouquet, Clara Mouton Perrot, Julien Moyet, Caroline Mudara, Aisha Kalsoom Mufti, Ng Yong Muh, Dzawani Muhamad, Jimmy Mullaert, Fredrik Müller, Karl Erik Müller, Syed Muneeb, Nadeem Munir, Laveena Munshi, Aisling Murphy, Lorna Murphy, Marlène Murris, Srinivas Murthy, Himed Musaab, Himasha Muvindi, Gugapriyaa Muyandy, Dimitra Melia Myrodia, Farah Nadia Mohd-Hanafiah, Dave Nagpal, Alex Nagrebetsky, Mangala Narasimhan, Nageswaran Narayanan, Rashid Nasim Khan, Alasdair Nazerali-Maitland, Nadège Neant, Holger Neb, Erni Nelwan, Raul Neto, Emily Neumann, Pauline Yeung Ng, Wing Yiu Ng, Anthony Nghi, Duc Nguyen, Orna Ni Choileain, Niamh Ni Leathlobhair, Prompak Nitayavardhana, Stephanie Nonas, Nurul Amani Mohd Noordin, Marion Noret, Nurul Faten Izzati Norharizam, Lisa Norman, Alessandra Notari, Mahdad Noursadeghi, Karolina Nowicka, Adam Nowinski, Saad Nseir, Jose I Nunez, Nurnaningsih Nurnaningsih, Dwi Utomo Nusantara, Elsa Nyamankolly, Fionnuala O Brien, Annmarie O Callaghan, Annmarie O'Callaghan, Giovanna Occhipinti, Derbrenn OConnor, Max O'Donnell, Tawnya Ogston, Takayuki Ogura, Tak-Hyuk Oh, Sophie O'Halloran, Katie O'Hearn, Shinichiro Ohshimo, Agnieszka Oldakowska, João Oliveira, Larissa Oliveira, Jee Yan Ong, Wilna Oosthuyzen, Anne Opavsky, Peter Openshaw, Saijad Orakzai, Claudia Milena Orozco-Chamorro, Jamel Ortoleva, Javier Osatnik, Linda O'Shea, Miriam O'Sullivan, Siti Zubaidah Othman, Nadia Ouamara, Rachida Ouissa, Eric Oziol, Maïder Pagadoy, Justine Pages, Mario Palacios, Amanda Palacios, Massimo Palmarini, Giovanna Panarello, Hem Paneru, Lai Hui Pang, Mauro Panigada, Nathalie Pansu, Aurélie Papadopoulos, Rachael Parke, Melissa Parker, Briseida Parra, Taha Pasha, Jérémie Pasquier, Bruno Pastene, Fabian Patauner, Drashti Patel, Mohan Dass Pathmanathan, Luís Patrão, Patricia Patricio, Juliette Patrier, Lisa Patterson, Rajyabardhan Pattnaik, Mical Paul, Christelle Paul, Jorge Paulos, William A Paxton, Jean-François Payen, Kalaiarasu Peariasamy, Giles J Peek, Florent Peelman, Nathan Peiffer-Smadja, Vincent Peigne, Mare Pejkovska, Paolo Pelosi, Ithan D Peltan, Rui Pereira, Daniel Perez, Luis Periel, Thomas Perpoint, Antonio Pesenti, Vincent Pestre, Lenka Petrou, Ventzislava Petrov-Sanchez, Frank Olav Pettersen, Gilles Peytavin, Scott Pharand, Michael Piagnerelli, Walter Picard, Olivier Picone, Maria de Piero, Carola Pierobon, Djura Piersma, Carlos Pimentel, Raquel Pinto, Catarina Pires, Isabelle Pironneau, Lionel Piroth, Ayodhia Pitaloka, Riinu Pius, Laurent Plantier, Hon Shen Png, Julien Poissy, Ryadh Pokeerbux, Maria Pokorska-Spiewak, Sergio Poli, Georgios Pollakis, Diane Ponscarme, Jolanta Popielska, Diego Bastos Porto, Andra-Maris Post, Douwe F Postma, Pedro Povoa, Diana Póvoas, Jeff Powis, Sofia Prapa, Sébastien Preau, Christian Prebensen, Jean-Charles Preiser, Anton Prinssen, Gamage Dona Dilanthi Priyadarshani, Lucia Proença, Sravya Pudota, Oriane Puéchal, Bambang Pujo Semedi, Mathew Pulicken, Gregory Purcell, Luisa Quesada, Vilmaris Quinones-Cardona, Víctor Quirós González, Else Quist-Paulsen, Mohammed Quraishi, Maia Rabaa, Christian Rabaud, Ebenezer Rabindrarajan, Aldo Rafael, Marie Rafiq, Gabrielle Ragazzo, Mutia Rahardjani, Rozanah Abd Rahman, Ahmad Kashfi Haji Ab Rahman, Arsalan Rahutullah, Fernando Rainieri, Giri Shan Rajahram, Pratheema Ramachandran, Ahmad Afiq Ramli, Blandine Rammaert, Asim Rana, Rajavardhan Rangappa, Ritika Ranjan, Christophe Rapp, Aasiyah Rashan, Thalha Rashan, Ghulam Rasheed, Menaldi Rasmin, Indrek Rätsep, Cornelius Rau, Tharmini Ravi, Ali Raza, Andre Real, Stanislas Rebaudet, Sarah Redl, Brenda Reeve, Attaur Rehman, Liadain Reid, Dag Henrik Reikvam, Renato Reis, Jordi Rello, Jonathan Remppis, Martine Remy, Hongru Ren, Hanna Renk, Anne-Sophie Resseguier, Matthieu Revest, Oleksa Rewa, Luis Felipe Reyes, Tiago Reyes, Maria Ines Ribeiro, Antonia Ricchiuto, David Richardson, Denise Richardson, Laurent Richier, Siti Nurul Atikah Ahmad Ridzuan, Jordi Riera, Ana L Rios, Asgar Rishu, Patrick Rispal, Karine Risso, Maria Angelica Rivera Nuñez, Nicholas Rizer, Chiara Robba, André Roberto, Stephanie Roberts, David L Robertson, Olivier Robineau, Ferran Roche-Campo, Paola Rodari, Simão Rodeia, Bernhard Roessler, Pierre-Marie Roger, Emmanuel Roilides, Juliette Romaru, Roberto Roncon-Albuquerque, Mélanie Roriz, Manuel Rosa-Calatrava, Michael Rose, Dorothea Rosenberger, Nurul Hidayah Mohammad Roslan, Andrea Rossanese, Matteo Rossetti, Bénédicte Rossignol, Patrick Rossignol, Stella Rousset, Carine Roy, Benoît Roze, Desy Rusmawatiningtyas, Clark D Russell, Maria Ryan, Maeve Ryan, Steffi Ryckaert, Aleksander Rygh Holten, Isabela Saba, Sairah Sadaf, Musharaf Sadat, Valla Sahraei, Maximilien Saint-Gilles, Pranya Sakiyalak, Nawal Salahuddin, Leonardo Salazar, Jodat Saleem, Gabriele Sales, Stéphane Sallaberry, Charlotte Salmon Gandonniere, Hélène Salvator, Olivier Sanchez, Angel Sanchez-Miralles, Vanessa Sancho-Shimizu, Gyan Sandhu, Zulfiqar Sandhu, Pierre-François Sandrine, Marlene Santos, Shirley Sarfo-Mensah, Bruno Sarmento Banheiro, Iam Claire E Sarmiento, Benjamine Sarton, Ankana Satya, Sree Satyapriya, Rumaisah Satyawati, Egle Saviciute, Parthena Savvidou, Yen Tsen Saw, Justin Schaffer, Tjard Schermer, Arnaud Scherpereel, Marion Schneider, Stephan Schroll, Michael Schwameis, Gary Schwartz, Brendan Scicluna, Janet T Scott, James Scott-Brown, Nicholas Sedillot, Tamara Seitz, Jaganathan Selvanayagam, Mageswari Selvarajoo, Caroline Semaille, Rasidah Bt Senian, Eric Senneville, Claudia Sepulveda, Filipa Sequeira, Tânia Sequeira, Ary Serpa Neto, Pablo Serrano Balazote, Ellen Shadowitz, Syamin Asyraf Shahidan, Mohammad Shamsah, Anuraj Shankar, Shaikh Sharjeel, Catherine A Shaw, Victoria Shaw, Ashraf Sheharyar, Rohan Shetty, Rajesh Mohan Shetty, Haixia Shi, Nisreen Shiban, Mohiuddin Shiekh, Nobuaki Shime, Hiroaki Shimizu, Keiki Shimizu, Sally Shrapnel, Pramesh Sundar Shrestha, Shubha Kalyan Shrestha, Hoi Ping Shum, Nassima Si Mohammed, Ng Yong Siang, Jeanne Sibiude, Atif Siddiqui, Piret Sillaots, Catarina Silva, Rogério Silva, Maria Joao Silva, Wai Ching Sin, Dario Sinatti, Punam Singh, Budha Charan Singh, Pompini Agustina Sitompul, Karisha Sivam, Vegard Skogen, Sue Smith, Benjamin Smood, Coilin Smyth, Michelle Smyth, Morgane Snacken, Dominic So, Tze Vee Soh, Joshua Solomon, Tom Solomon, Agnès Sommet, Rima Song, Tae Song, Jack Song Chia, Michael Sonntagbauer, Azlan Mat Soom, Alberto Sotto, Edouard Soum, Marta Sousa, Ana Chora Sousa, Maria Sousa Uva, Vicente Souza-Dantas, Alexandra Sperry, Elisabetta Spinuzza, B P Sanka Ruwan Sri Darshana, Shiranee Sriskandan, Sarah Stabler, Thomas Staudinger, Stephanie-Susanne Stecher, Trude Steinsvik, Ymkje Stienstra, Birgitte Stiksrud, Eva Stolz, Amy Stone, Adrian Streinu-Cercel, David Stuart, Ami Stuart, Decy Subekti, Gabriel Suen, Jacky Y Suen, Asfia Sultana, Charlotte Summers, Dubravka Supic, Deepashankari Suppiah, Magdalena Surovcová, Suwarti Suwarti, Andrey Svistunov, Sarah Syahrin, Konstantinos Syrigos, Jaques Sztajnbok, Konstanty Szuldrzynski, Shirin Tabrizi, Lysa Tagherset, Shahdattul Mawarni Taib, Ewa Talarek, Sara Taleb, Jelmer Talsma, Renaud Tamisier, Maria Lawrensia Tampubolon, Kim Keat Tan, Yan Chyi Tan, Taku Tanaka, Hiroyuki Tanaka, Hayato Taniguchi, Huda Taqdees, Arshad Taqi, Coralie Tardivon, Pierre Tattevin, M Azhari Taufik, Hassan Tawfik, Richard S Tedder, Tze Yuan Tee, João Teixeira, Sofia Tejada, Marie-Capucine Tellier, Sze Kye Teoh, Vanessa Teotonio, François Téoulé, Pleun Terpstra, Olivier Terrier, Nicolas Terzi, Hubert Tessier-Grenier, Adrian Tey, Alif Adlan Mohd Thabit, Anand Thakur, Zhang Duan Tham, Suvintheran Thangavelu, Vincent Thibault, Simon-Djamel Thiberville, Benoît Thill, Jananee Thirumanickam, Shaun Thompson, Emma C Thomson, David Thomson, Surain Raaj Thanga Thurai, Ryan S Thwaites, Paul Tierney, Vadim Tieroshyn, Peter S Timashev, Jean-François Timsit, Noémie Tissot, Jordan Zhien Yang Toh, Maria Toki, Kristian Tonby, Sia Loong Tonnii, Margarida Torres, Antoni Torres, Rosario Maria Torres Santos-Olmo, Hernando Torres-Zevallos, Michael Towers, Tony Trapani, Théo Treoux, Cécile Tromeur, Ioannis Trontzas, Tiffany Trouillon, Jeanne Truong, Christelle Tual, Sarah Tubiana, Helen Tuite, Jean-Marie Turmel, Lance C W Turtle, Anders Tveita, Pawel Twardowski, Makoto Uchiyama, P G Ishara Udayanga, Andrew Udy, Roman Ullrich, Alberto Uribe, Asad Usman, Timothy M Uyeki, Cristinava Vajdovics, Piero Valentini, Luís Val-Flores, Amélie Valran, Stijn Van de Velde, Marcel van den Berge, Machteld Van der Feltz, Job van der Palen, Paul van der Valk, Nicky Van Der Vekens, Peter Van der Voort, Sylvie Van Der Werf, Laura van Gulik, Jarne Van Hattem, Carolien van Netten, 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Munblit, Daniel, Nekliudov, Nikita A, Nichol, Alistair D, Singh Oinam, Budha Charan, Ong, David, Panda, Prasan Kumar, Petrovic, Michele, Pritchard, Mark G, Ramakrishnan, Nagarajan, Ramos, Grazielle Viana, Roger, Claire, Sandulescu, Oana, Semple, Malcolm G, Sharma, Pratima, Sigfrid, Louise, Somers, Emily C, Streinu-Cercel, Anca, Taccone, Fabio, Vecham, Pavan Kumar, Kumar Tirupakuzhi Vijayaraghavan, Bharath, Wei, Jia, Wils, Evert-Jan, Ci Wong, Xin, Horby, Peter, Rojek, Amanda, Olliaro, Piero L, ISARIC Clinical Characterisation Group: Ali Abbas, Sheryl Ann Abdukahil, Nurul Najmee Abdulkadir, Ryuzo Abe, Laurent Abel, Lara Absil, Subhash Acharya, Andrew Acker, Elisabeth Adam, Diana Adrião, Saleh Al Ageel, Shakeel Ahmed, Kate Ainscough, Eka Airlangga, Tharwat Aisa, Ali Ait Hssain, Younes Ait Tamlihat, Takako Akimoto, Ernita Akmal, Eman Al Qasim, Razi Alalqam, Angela Alberti, Tala Al-Dabbous, Senthilkumar Alegesan, Cynthia Alegre, Marta Alessi, Beatrice Alex, Kévin Alexandre, Abdulrahman Al-Fares, Huda Alfoudri, Imran Ali, Adam Ali, Naseem Ali Shah, Kazali Enagnon Alidjnou, Jeffrey Aliudin, Qabas Alkhafajee, Clotilde Allavena, Nathalie Allou, Aneela Altaf, João Alves, Rita Alves, João Melo Alves, Maria Amaral, Nur Amira, Phoebe Ampaw, Roberto Andini, Claire Andréjak, Andrea Angheben, François Angoulvant, Séverine Ansart, Sivanesen Anthonidass, Massimo Antonelli, Carlos Alexandre Antunes de Brito, Ardiyan Apriyana, Yaseen Arabi, Irene Aragao, Francisco Arancibia, Carolline Araujo, Antonio Arcadipane, Patrick Archambault, Lukas Arenz, Jean-Benoît Arlet, Christel Arnold-Day, Lovkesh Arora, Rakesh Arora, Elise Artaud-Macari, Diptesh Aryal, Angel Asensio, Muhammad Ashraf, Namra Asif, Mohammad Asim, Jean Baptiste Assie, Amirul Asyraf, Anika Atique, A M Udara Lakshan Attanyake, Johann Auchabie, Hugues Aumaitre, Adrien Auvet, Laurène Azemar, Cecile Azoulay, Benjamin Bach, Delphine Bachelet, Claudine Badr, Nadia Baig, J Kevin Baird, Erica Bak, Agamemnon Bakakos, Nazreen Abu Bakar, Andriy Bal, Mohanaprasanth Balakrishnan, Valeria Balan, Firouzé Bani-Sadr, Renata Barbalho, Nicholas Yuri Barbosa, Wendy S Barclay, Saef Umar Barnett, Michaela Barnikel, Helena Barrasa, Audrey Barrelet, Cleide Barrigoto, Marie Bartoli, Mustehan Bashir, Romain Basmaci, Muhammad Fadhli Hassin Basri, Denise Battaglini, Jules Bauer, Diego Fernando Bautista Rincon, Denisse Bazan Dow, Alexandra Bedossa, Ker Hong Bee, Husna Begum, Sylvie Behilill, Albertus Beishuizen, Aleksandr Beljantsev, David Bellemare, Anna Beltrame, Beatriz Amorim Beltrão, Marine Beluze, Nicolas Benech, Lionel Eric Benjiman, Dehbia Benkerrou, Suzanne Bennett, Luís Bento, Jan-Erik Berdal, Delphine Bergeaud, Hazel Bergin, José Luis Bernal Sobrino, Giulia Bertoli, Lorenzo Bertolino, Simon Bessis, Sybille Bevilcaqua, Karine Bezulier, Amar Bhatt, Krishna Bhavsar, Claudia Bianco, Farah Nadiah Bidin, Moirangthem Bikram Singh, Felwa Bin Humaid, Mohd Nazlin Bin Kamarudin, François Bissuel, Patrick Biston, Laurent Bitker, Jonathan Bitton, Pablo Blanco-Schweizer, Catherine Blier, Frank Bloos, Mathieu Blot, Filomena Boccia, Laetitia Bodenes, Alice Bogaarts, Debby Bogaert, Anne-Hélène Boivin, Pierre-Adrien Bolze, François Bompart, Aurelius Bonfasius, Diogo Borges, Raphaël Borie, Hans Martin Bosse, Elisabeth Botelho-Nevers, Lila Bouadma, Olivier Bouchaud, Sabelline Bouchez, Dounia Bouhmani, Damien Bouhour, Kévin Bouiller, Laurence Bouillet, Camile Bouisse, Anne-Sophie Boureau, John Bourke, Maude Bouscambert, Aurore Bousquet, Jason Bouziotis, Bianca Boxma, Marielle Boyer-Besseyre, Maria Boylan, Axelle Braconnier, Cynthia Braga, Timo Brandenburger, Filipa Brás Monteiro, Luca Brazzi, Patrick Breen, Dorothy Breen, Patrick Breen, Kathy Brickell, Shaunagh Browne, Alex Browne, Nicolas Brozzi, Marjolein Brusse-Keizer, Nina Buchtele, Christian Buesaquillo, Polina Bugaeva, Marielle Buisson, Danilo Buonsenso, Erlina Burhan, Ingrid G Bustos, Denis Butnaru, André Cabie, Susana Cabral, Eder Caceres, Cyril Cadoz, Mia Callahan, Kate Calligy, Jose Andres Calvache, João Camões, Valentine Campana, Paul Campbell, Josie Campisi, Cecilia Canepa, Mireia Cantero, Pauline Caraux-Paz, Sheila Cárcel, Chiara Simona Cardellino, Sofia Cardoso, Filipe Cardoso, Filipa Cardoso, Nelson Cardoso, Simone Carelli, Nicolas Carlier, Thierry Carmoi, Gayle Carney, Inês Carqueja, Marie-Christine Carret, François Martin Carrier, Ida Carroll, Maire-Laure Casanova, Mariana Cascão, Siobhan Casey, José Casimiro, Bailey Cassandra, Silvia Castañeda, Nidyanara Castanheira, Guylaine Castor-Alexandre, Henry Castrillón, Ivo Castro, Ana Catarino, François-Xavier Catherine, Paolo Cattaneo, Roberta Cavalin, Giulio Giovanni Cavalli, Alexandros Cavayas, Adrian Ceccato, Minerva Cervantes-Gonzalez, Anissa Chair, Catherine Chakveatze, Adrienne Chan, Meera Chand, Christelle Chantalat Auger, Jean-Marc Chapplain, Julie Chas, Allegra Chatterjee, Mobin Chaudry, Jonathan Samuel Chávez Iñiguez, Anjellica Chen, Yih-Sharng Chen, Matthew Pellan Cheng, Antoine Cheret, Thibault Chiarabini, Julian Chica, Suresh Kumar Chidambaram, Leong Chin Tho, Catherine Chirouze, Davide Chiumello, Sung-Min Cho, Bernard Cholley, Marie-Charlotte Chopin, Ting Soo Chow, Yock Ping Chow, Hiu Jian Chua, Jonathan Chua, Jose Pedro Cidade, José Miguel Cisneros Herreros, Anna Ciullo, Jennifer Clarke, Emma Clarke, Rolando Claure-Del Granado, Sara Clohisey, Perren J Cobb, Cassidy Codan, Caitriona Cody, Alexandra Coelho, Megan Coles, Gwenhaël Colin, Michael Collins, Sebastiano Maria Colombo, Pamela Combs, Marie Connor, Anne Conrad, Sofía Contreras, Elaine Conway, Graham S Cooke, Mary Copland, Hugues Cordel, Amanda Corley, Sabine Cornelis, Alexander Daniel Cornet, Arianne Joy Corpuz, Andrea Cortegiani, Grégory Corvaisier, Emma Costigan, Camille Couffignal, Sandrine Couffin-Cadiergues, Roxane Courtois, Stéphanie Cousse, Rachel Cregan, Charles Crepy D'Orleans, Cosimo Cristella, Sabine Croonen, Gloria Crowl, Jonathan Crump, Claudina Cruz, Juan Luis Cruz Berm, Jaime Cruz Rojo, Marc Csete, Ailbhe Cullen, Matthew Cummings, Gerard Curley, Elodie Curlier, Colleen Curran, Paula Custodio, Ana da Silva Filipe, Charlene Da Silveira, Al-Awwab Dabaliz, Darren Dahly, Heidi Dalton, Jo Dalton, Seamus Daly, Nick Daneman, Corinne Daniel, Jorge Dantas, Frédérick D'Aragon, Menno de Jong, Gillian de Loughry, Diego de Mendoza, Etienne De Montmollin, Rafael Freitas de Oliveira França, Ana Isabel de Pinho Oliveira, Rosanna De Rosa, Cristina De Rose, Thushan de Silva, Peter de Vries, Jillian Deacon, David Dean, Alexa Debard, Marie-Pierre Debray, Nathalie DeCastro, William Dechert, Lauren Deconninck, Romain Decours, Eve Defous, Isabelle Delacroix, Eric Delaveuve, Karen Delavigne, Nathalie M Delfos, Ionna Deligiannis, Andrea Dell'Amore, Christelle Delmas, Pierre Delobel, Corine Delsing, Elisa Demonchy, Emmanuelle Denis, Dominique Deplanque, Pieter Depuydt, Mehul Desai, Diane Descamps, Mathilde Desvallées, Santi Dewayanti, Pathik Dhanger, Alpha Diallo, Sylvain Diamantis, André Dias, Juan Jose Diaz, Priscila Diaz, Rodrigo Diaz, Kévin Didier, Jean-Luc Diehl, Wim Dieperink, Jérôme Dimet, Vincent Dinot, Fara Diop, Alphonsine Diouf, Yael Dishon, Félix Djossou, Annemarie B Docherty, Helen Doherty, Arjen M Dondorp, Andy Dong, Maria Donnelly, Sean Donohue, Yoann Donohue, Chloe Donohue, Peter Doran, Céline Dorival, Eric D'Ortenzio, James Joshua Douglas, Renee Douma, Nathalie Dournon, Triona Downer, Joanne Downey, Mark Downing, Tom Drake, Aoife Driscoll, Murray Dryden, Murray Dryden, Claudio Duarte Fonseca, Vincent Dubee, François Dubos, Alexandre Ducancelle, Toni Duculan, Susanne Dudman, Abhijit Duggal, Paul Dunand, Mathilde Duplaix, Emanuele Durante-Mangoni, Lucian Durham, Bertrand Dussol, Juliette Duthoit, Xavier Duval, Anne Margarita Dyrhol-Riise, Sim Choon Ean, Marco Echeverria-Villalobos, Siobhan Egan, Carla Eira, Mohammed El Sanharawi, Subbarao Elapavaluru, Brigitte Elharrar, Jacobien Ellerbroek, Philippine Eloy, Tarek Elshazly, Iqbal Elyazar, Isabelle 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Srinivas Murthy, Himed Musaab, Himasha Muvindi, Gugapriyaa Muyandy, Dimitra Melia Myrodia, Farah Nadia Mohd-Hanafiah, Dave Nagpal, Alex Nagrebetsky, Mangala Narasimhan, Nageswaran Narayanan, Rashid Nasim Khan, Alasdair Nazerali-Maitland, Nadège Neant, Holger Neb, Erni Nelwan, Raul Neto, Emily Neumann, Pauline Yeung Ng, Wing Yiu Ng, Anthony Nghi, Duc Nguyen, Orna Ni Choileain, Niamh Ni Leathlobhair, Prompak Nitayavardhana, Stephanie Nonas, Nurul Amani Mohd Noordin, Marion Noret, Nurul Faten Izzati Norharizam, Lisa Norman, Alessandra Notari, Mahdad Noursadeghi, Karolina Nowicka, Adam Nowinski, Saad Nseir, Jose I Nunez, Nurnaningsih Nurnaningsih, Dwi Utomo Nusantara, Elsa Nyamankolly, Fionnuala O Brien, Annmarie O Callaghan, Annmarie O'Callaghan, Giovanna Occhipinti, Derbrenn OConnor, Max O'Donnell, Tawnya Ogston, Takayuki Ogura, Tak-Hyuk Oh, Sophie O'Halloran, Katie O'Hearn, Shinichiro Ohshimo, Agnieszka Oldakowska, João Oliveira, Larissa Oliveira, Jee Yan Ong, Wilna Oosthuyzen, Anne 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Helen Tuite, Jean-Marie Turmel, Lance C W Turtle, Anders Tveita, Pawel Twardowski, Makoto Uchiyama, P G Ishara Udayanga, Andrew Udy, Roman Ullrich, Alberto Uribe, Asad Usman, Timothy M Uyeki, Cristinava Vajdovics, Piero Valentini, Luís Val-Flores, Amélie Valran, Stijn Van de Velde, Marcel van den Berge, Machteld Van der Feltz, Job van der Palen, Paul van der Valk, Nicky Van Der Vekens, Peter Van der Voort, Sylvie Van Der Werf, Laura van Gulik, Jarne Van Hattem, Carolien van Netten, Frank van Someren Greve, Ilonka van Veen, Hugo Van Willigen, Noémie Vanel, Henk Vanoverschelde, Pooja Varghese, Michael Varrone, Shoban Raj Vasudayan, Charline Vauchy, Shaminee Veeran, Aurélie Veislinger, Sebastian Vencken, Sara Ventura, Annelies Verbon, James Vickers, José Ernesto Vidal, César Vieira, Deepak Vijayan, Joy Ann Villanueva, Judit Villar, Pierre-Marc Villeneuve, Andrea Villoldo, Gayatri Vishwanathan, Benoit Visseaux, Hannah Visser, Chiara Vitiello, Harald Vonkeman, Fanny Vuotto, Suhaila Abdul Wahab, Noor Hidayu Wahab, Nadirah Abdul Wahid, Marina Wainstein, Wan Fadzlina Wan Muhd Shukeri, Chih-Hsien Wang, Steve Webb, Katharina Weil, Tan Pei Wen, Sanne Wesselius, T Eoin West, Murray Wham, Bryan Whelan, Nicole White, Paul Henri Wicky, Aurélie Wiedemann, Surya Otto Wijaya, Keith Wille, Suzette Willems, Virginie Williams, Calvin Wong, Yew Sing Wong, Teck Fung Wong, Natalie Wright, Gan Ee Xian, Lim Saio Xian, Kuan Pei Xuan, Ioannis Xynogalas, Siti Rohani Binti Mohd Yakop, Masaki Yamazaki, Yazdan Yazdanpanah, Nicholas Yee Liang Hing, Cécile Yelnik, Chian Hui Yeoh, Stephanie Yerkovich, Toshiki Yokoyama, Hodane Yonis, Obada Yousif, Saptadi Yuliarto, Akram Zaaqoq, Marion Zabbe, Kai Zacharowski, Masliza Zahid, Maram Zahran, Nor Zaila Binti Zaidan, Maria Zambon, Miguel Zambrano, Alberto Zanella, Konrad Zawadka, Nurul Zaynah, Hiba Zayyad, Alexander Zoufaly, David Zucman, University of Oxford, Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, CHU Pontchaillou [Rennes], ARN régulateurs bactériens et médecine (BRM), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), This work was made possible by the UK Foreign, Commonwealth and Development Office, Wellcome (215091/Z/18/Z, 205228/Z/16/Z, 220757/Z/20/Z), Bill & Melinda Gates Foundation (OPP1209135), UK Medical Research Council Clinical Research Training Fellowship (MR/V001671/1), the philanthropic support of the donors to the University of Oxford’s COVID-19 Research Response Fund, CIHR Coronavirus Rapid Research Funding Opportunity (OV2170359) and the co-ordination in Canada by Sunnybrook Research Institute, endorsement of the Irish Critical Care—Clinical Trials Group, co-ordination in Ireland by the Irish Critical Care—Clinical Trials Network at University College Dublin and funding by the Health Research Board of Ireland (CTN-2014–12), the Rapid European COVID-19 Emergency Response research (RECOVER) (H2020 project 101003589) and European Clinical Research Alliance on Infectious Diseases (ECRAID) (965313), the COVID clinical management team, AIIMS, Rishikesh, India, the COVID-19 Clinical Management team, Manipal Hospital Whitefield, Bengaluru, India, Cambridge NIHR Biomedical Research Centre, the dedication and hard work of the Groote Schuur Hospital Covid ICU Team, support by the Groote Schuur nursing and University of Cape Town registrar bodies co-ordinated by the Division of Critical Care at the University of Cape Town, the Liverpool School of Tropical Medicine and the University of Oxford, the dedication and hard work of the Norwegian SARS-CoV-2 study team, the Research Council of Norway (grant no. 312780) and a philanthropic donation from Vivaldi Invest A/S owned by Jon Stephenson von Tetzchner, Imperial NIHR Biomedical Research Centre, the Comprehensive Local Research Networks of which PJMO is an NIHR Senior Investigator (NIHR201385), Innovative Medicines Initiative Joint Undertaking under Grant Agreement No. 115523 COMBACTE, resources of which are composed of financial contribution from the European Union’s Seventh Framework Programme (FP7/2007– 2013) and EFPIA companies, in-kind contribution, the French COVID cohort (NCT04262921) is sponsored by INSERM and is funded by the REACTing (REsearch & ACtion emergING infectious diseases) consortium and by a grant of the French Ministry of Health (PHRC n 20–0424), Stiftungsfonds zur Förderung der Bekämpfung der Tuberkulose und anderer Lungenkrankheiten of the City of Vienna (project no. APCOV22BGM), Italian Ministry of Health ‘Fondi Ricerca corrente–L1P6’ to IRCCS Ospedale Sacro Cuore–Don Calabria, Australian Department of Health grant (3273191), Gender Equity Strategic Fund at University of Queensland, Artificial Intelligence for Pandemics (A14PAN) at University of Queensland, the Australian Research Council Centre of Excellence for Engineered Quantum Systems (EQUS, CE170100009), the Prince Charles Hospital Foundation, Australia, grants from Instituto de Salud Carlos III, Ministerio de Ciencia, Spain, Brazil, National Council for Scientific and Technological Development (scholarship no. 303953/2018–7), the Firland Foundation, Shoreline, Washington, USA, a grant from foundation Bevordering Onderzoek Franciscus, the South Eastern Norway Health Authority and the Research Council of Norway, and preparedness work conducted by the Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection. Data and Material provision was supported by grants from the National Institute for Health Research (NIHR, award CO-CIN-01), the Medical Research Council (MRC, and grant MC_PC_19059) and by the NIHR Health Protection Research Unit (HPRU) in Emerging and Zoonotic Infections at University of Liverpool in partnership with PHE (award no. 200907), NIHR HPRU in Respiratory Infections at Imperial College London with PHE (award no. 200927), Liverpool Experimental Cancer Medicine Centre (grant no. C18616/A25153), NIHR Biomedical Research Centre at Imperial College London (award no. IS-BRC-1215–20013) and NIHR Clinical Research Network providing infrastructure support.
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Male ,Epidemiology ,MESH: Hospitalization ,MESH: Proportional Hazards Models ,MESH: Risk Factors ,Risk Factors ,MESH: Child ,cohort study ,MESH: COVID-19 ,Humans ,MESH: SARS-CoV-2 ,Child ,Proportional Hazards Models ,MESH: Humans ,MESH: Middle Aged ,SARS-CoV-2 ,COVID-19 ,risk of death ,General Medicine ,Middle Aged ,co-morbidities ,symptoms ,treatments ,MESH: Male ,Hospitalization ,Intensive Care Units ,MESH: Intensive Care Units ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,COVID-19/therapy - Abstract
Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death.
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- 2023
8. Schroth Physiotherapeutic Scoliosis-Specific Exercise (PSSE) Trials—Systematic Review of Methods and Recommendations for Future Research
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Schreiber, Sanja, primary, Whibley, Daniel, additional, and Somers, Emily C, additional
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- 2023
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9. Supplemental Material - Cost-related prescription non-adherence and patient-reported outcomes in systemic lupus erythematosus: The Michigan Lupus Epidemiology & Surveillance program
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Minhas, Deeba, Marder, Wendy, Hassett, Afton L, Zick, Suzanna M, Gordon, Caroline, Harlow, Sioban D, Wang, Lu, Barbour, Kamil E, Helmick, Charles G, McCune, W Joseph, and Somers, Emily C
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Aged Health Care - Abstract
Supplemental Material for Cost-related prescription non-adherence and patient-reported outcomes in systemic lupus erythematosus: The Michigan Lupus Epidemiology & Surveillance program by Deeba Minhas, Wendy Marder, Afton L Hassett, Suzanna M Zick, Caroline Gordon, Sioban D Harlow, Lu Wang, Kamil E Barbour, Charles G Helmick, W Joseph McCune and Emily C Somers in Lupus
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- 2023
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10. Cost-related prescription non-adherence and patient-reported outcomes in systemic lupus erythematosus: The Michigan Lupus Epidemiology & Surveillance program.
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Minhas, Deeba, Marder, Wendy, Hassett, Afton L, Zick, Suzanna M, Gordon, Caroline, Harlow, Sioban D, Wang, Lu, Barbour, Kamil E, Helmick, Charles G, McCune, W Joseph, and Somers, Emily C
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SYSTEMIC lupus erythematosus ,HEALTH insurance ,EPIDEMIOLOGY ,PATIENT compliance ,MEDICAL prescriptions - Abstract
Objectives: Medication access and adherence play key roles in determining patient outcomes. We investigated whether cost-related non-adherence (CRNA) to prescription medications was associated with worse patient-reported outcomes in a population-based systemic lupus erythematosus (SLE) cohort. Methods: Sociodemographic and prescription data were collected by structured interviews in 2014–2015 from patients meeting SLE criteria in the established Michigan Lupus Epidemiology & Surveillance (MILES) Cohort. We examined the associations between CRNA and potential confounders such as sociodemographics and health insurance coverage, and outcome measures of SLE activity and damage using multivariable linear regression. Results: 462 SLE participants completed the study visit: 430 (93.1%) female, 208 (45%) Black, and mean age 53.3 years. 100 (21.6%) participants with SLE reported CRNA in the preceding 12 months. After adjusting for covariates, CRNA was associated with both higher levels of current SLE disease activity [SLAQ: β coeff 2.7 (95% CI 1.3, 4.1), p < 0.001] and damage [LDIQ β coeff 1.4 (95% CI 0.5, 2.4), p = 0.003]. Race, health insurance status, and fulfilling Fibromyalgia (FM) Survey Criteria were independently associated with both higher (worse) SLAQ and LDIQ scores; female sex was further associated with higher SLAQ scores. Conclusion: Patients with SLE who reported CRNA in the previous 12 months had significantly worse self-reported current disease activity and damage scores compared to those not reporting CRNA. Raising awareness and addressing barriers or concerns related to financial implications and accessibility issues in care plans may help to improve these outcomes. [ABSTRACT FROM AUTHOR]
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- 2023
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11. Incidence rates of systemic lupus erythematosus in the USA: estimates from a meta-analysis of the Centers for Disease Control and Prevention national lupus registries
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Izmirly, Peter M, primary, Ferucci, Elizabeth D, additional, Somers, Emily C, additional, Wang, Lu, additional, Lim, S Sam, additional, Drenkard, Cristina, additional, Dall'Era, Maria, additional, McCune, W Joseph, additional, Gordon, Caroline, additional, Helmick, Charles, additional, and Parton, Hilary, additional
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- 2021
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12. Autoimmune Diseases Co-Occurring within Individuals and within Families: A Systematic Review
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Somers, Emily C., Thomas, Sara L., Smeeth, Liam, and Hall, Andrew J.
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- 2006
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13. Access and cost-related non-adherence to prescription medications among lupus cases and controls: the Michigan Lupus Epidemiology & Surveillance (MILES) Program
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Minhas, Deeba, Marder, Wendy, Harlow, Sioban, Hassett, Afton L., Zick, Suzanna M., Gordon, Caroline, Barbour, Kamil E., Helmick, Charles G., Wang, Lu, Lee, Jiha, Padda, Amrita, McCune, W. Joseph, and Somers, Emily C.
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Adult ,Male ,Michigan ,Drug Substitution ,Middle Aged ,Article ,Drug Costs ,Health Services Accessibility ,Medication Adherence ,Interviews as Topic ,Cost Savings ,Case-Control Studies ,Population Surveillance ,Humans ,Lupus Erythematosus, Systemic ,Female ,Registries ,Health Expenditures ,Aged - Abstract
Medication access and adherence are important determinants of health outcomes. We investigated factors associated with access and cost-related nonadherence to prescriptions in a population-based cohort of systemic lupus erythematosus (SLE) patients and controls.Detailed sociodemographic and prescription data were collected by structured interview in 2014-2015 from participants in the Michigan Lupus Epidemiology and Surveillance (MILES) cohort. We compared access between cases and frequency-matched controls and examined associated factors in separate multivariable logistic regression models.A total of 654 participants (462 SLE patients, 192 controls) completed the baseline visit; 584 (89%) were female, 285 (44%) were Black, and the mean age was 53 years. SLE patients and controls reported similar frequencies of being unable to access prescribed medications (12.1% versus 9.4%, respectively; P was not significant). SLE patients were twice as likely as controls to report cost-related prescription nonadherence in the preceding 12 months to save money (21.7% versus 10.4%; P = 0.001) but were also more likely to ask their doctor for lower cost alternatives (23.8% versus 15.6%; P = 0.02). Disparities were found in association with income, race, and health insurance status, but the main findings persisted after adjusting for these and other variables in multivariable models.SLE patients were more likely than controls from the general population to report cost-related prescription nonadherence, including skipping doses, taking less medicine, and delaying filling prescriptions; yet,1 in 4 patients asked providers for lower cost medications. Consideration of medication costs in patient decision-making could provide a meaningful avenue for improving access and adherence to medications.
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- 2021
14. 1118 Incidence of systemic lupus erythematosus in the United States: estimates from a meta-analysis of the centers for disease control and prevention national lupus registries
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Izmirly, Peter M, primary, Ferucci, Elizabeth D, additional, Somers, Emily C, additional, Wang, Lu, additional, Joseph McCune, W, additional, Sam Lim, S, additional, Drenkard, Cristina, additional, Dall’Era, Maria, additional, Gordon, Caroline, additional, Helmick, Charles G, additional, and Parton, Hilary, additional
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- 2021
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15. Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases
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Hausmann, Jonathan S, primary, Kennedy, Kevin, additional, Simard, Julia F, additional, Liew, Jean W, additional, Sparks, Jeffrey A, additional, Moni, Tarin T, additional, Harrison, Carly, additional, Larché, Maggie J, additional, Levine, Mitchell, additional, Sattui, Sebastian E, additional, Semalulu, Teresa, additional, Foster, Gary, additional, Surangiwala, Salman, additional, Thabane, Lehana, additional, Beesley, Richard P, additional, Durrant, Karen L, additional, Mateus, Elsa F, additional, Mingolla, Serena, additional, Nudel, Michal, additional, Palmerlee, Candace A, additional, Richards, Dawn P, additional, Liew, David F L, additional, Hill, Catherine L, additional, Bhana, Suleman, additional, Costello, Wendy, additional, Grainger, Rebecca, additional, Machado, Pedro M, additional, Robinson, Philip C, additional, Sufka, Paul, additional, Wallace, Zachary S, additional, Yazdany, Jinoos, additional, Sirotich, Emily, additional, Robinson, Philip C., additional, Liew, Jean W., additional, Sufka, Paul H., additional, Singh, Namrata, additional, Howard, Richard A., additional, Kim, Alfred H.J., additional, Westrich-Robertson, Tiffany, additional, Tsui, Edmund, additional, Duarte-Garcia, Ali, additional, Sparks, Jeffrey A., additional, Tam, Herman, additional, Jayatilleke, Arundathi, additional, Konig, Maximilian F., additional, Graef, Elizabeth R., additional, Putman, Michael S., additional, Syed, Reema H., additional, Korsten, Peter, additional, Mateus, Elsa, additional, Sattui, Sebastian E., additional, Wallace, Zachary S., additional, Laura, Upton A., additional, Adam, Kilian, additional, Chock, Yu Pei Eugenia, additional, White, Douglas W., additional, Zamora, Geraldine T., additional, Traboco, Lisa S., additional, Patel, Aarat M., additional, Ugarte-Gil, Manuel F., additional, Gianfrancesco, Milena A., additional, Amigues, Isabelle, additional, Sanchez-Alvarez, Catalina, additional, Trupin, Laura, additional, Jacobsohn, Lindsay R., additional, Beesley, Richard P., additional, Hoyer, Bimba F., additional, Machado, Pedro M., additional, Makan, Kavita, additional, Gossec, Laure, additional, Priyank, Chaudhary, additional, Leipe, Jan, additional, Wallace, Beth, additional, Angeles-Han, Sheila T., additional, Almaghlouth, Ibrahim A., additional, Katherine, Wysham D., additional, Padula, Anthony S., additional, Berenbaum, Francis, additional, Treemarcki, Erin M., additional, Sinha, Rashmi, additional, Lewandowski, Laura B., additional, Webb, Kate, additional, Young, Kristen J., additional, Bulina, Inita, additional, Herrera Uribe, Sebastian, additional, Rubinstein, Tamar B., additional, Nolan, Marc W., additional, Ang, Elizabeth Y., additional, Venuturupalli, Swamy R., additional, Hausmann, Jonathan S., additional, Dubreuil, Maureen, additional, Pisoni, Cecilia N., additional, Cosatti, Micaela A., additional, Campos, Jose, additional, Simard, Julia F., additional, Conway, Richard, additional, Peterson, Tiffany M., additional, Harrison, Carly O., additional, Felix, Christele, additional, Richards, Dawn P., additional, Proulx, Laurie, additional, Akpabio, Akpabio A., additional, Worthing, Angus B., additional, Laidlaw, Lynn R., additional, Reid, Pankti, additional, Palmerlee, Candace A., additional, Danila, Maria I., additional, Sahar, Lotfi-Emran, additional, Linh, Ngo Q., additional, Agarwal, Arnav, additional, Studenic, Paul, additional, Liew, David F.L., additional, Larche, Maggie J., additional, Mingolla, Serena A.M., additional, Zamora, Erick A., additional, Angevare, Saskya S., additional, Sinha, Rashmi R., additional, Durrant, Karen L.W., additional, Peirce, Andrea, additional, Somers, Emily C., additional, Cappelli, Laura C., additional, Frankel, Brittany A., additional, Kumar, Bharat, additional, Silinsky Krupnikova, Sonia D., additional, Rosario Vega, Jorge A., additional, Frankovich, Jourdan, additional, Fernandez-Ruiz, Ruth, additional, Posada Velásquez, Marcela, additional, Yeoh, Su-Ann, additional, Marino, Maria, additional, Scott, Chrisiaan, additional, Rodríguez, Cecilia, additional, Martín Mancheño, Ana I., additional, Seo, Philip, additional, Gamboa-Cárdenas, Rocío V., additional, Pimentel-Quiroz, Victor R., additional, Reátegui-Sokolova, Cristina, additional, Kihara, Mari, additional, Lin, Chung M.A., additional, Kattula, Dheera, additional, Laila, Girgis, additional, Carmona, Loreto, additional, Wallace, John, additional, Gore-massy, Monique C., additional, Tomasella, Laura-Ann, additional, and Kodek, Moré A., additional
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- 2021
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16. Access and Cost‐Related Nonadherence to Prescription Medications Among Lupus Patients and Controls: The Michigan Lupus Epidemiology and Surveillance Program
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Minhas, Deeba, primary, Marder, Wendy, additional, Harlow, Sioban, additional, Hassett, Afton L., additional, Zick, Suzanna M., additional, Gordon, Caroline, additional, Barbour, Kamil E., additional, Helmick, Charles G., additional, Wang, Lu, additional, Lee, Jiha, additional, Padda, Amrita, additional, McCune, W. Joseph, additional, and Somers, Emily C., additional
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- 2021
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17. Incidence and Prevalence of Systemic Lupus Erythematosus Among Arab and Chaldean Americans in Southeastern Michigan: The Michigan Lupus Epidemiology and Surveillance Program
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Housey, Michelle, DeGuire, Peter, Lyon-Callo, Sarah, Wang, Lu, Marder, Wendy, McCune, W. Joseph, Helmick, Charles G, Gordon, Caroline, Dhar, J. Patricia, Leisen, James, and Somers, Emily C
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- 2015
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18. Chapter 23 - Environmental and drug-induced lupus
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Richardson, Bruce and Somers, Emily C.
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- 2021
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19. Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection
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Daniels, Curt J., Rajpal, Saurabh, Greenshields, Joel T., Rosenthal, Geoffrey L., Chung, Eugene H., Terrin, Michael, Jeudy, Jean, Mattson, Scott E., Law, Ian H., Borchers, James, Kovacs, Richard, Kovan, Jeffrey, Rifat, Sami F., Albrecht, Jennifer, Bento, Ana I., Albers, Lonnie, Bernhardt, David, Day, Carly, Hecht, Suzanne, Hipskind, Andrew, Mjaanes, Jeffrey, Olson, David, Rooks, Yvette L., Somers, Emily C., Tong, Matthew S., Wisinski, Jeffrey, Womack, Jason, Esopenko, Carrie, Kratochvil, Christopher J., and Rink, Lawrence D.
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Adult ,Male ,SARS-CoV-2 ,Research ,COVID-19 ,Magnetic Resonance Imaging, Cine ,United States ,Myocarditis ,Athletes ,Prevalence ,Online First ,Humans ,Mass Screening ,Female ,Registries ,Pandemics ,Comments ,Original Investigation - Abstract
This cohort study assesses the prevalence of myocarditis in athletes with COVID-19 and compare screening strategies for safe return to play., Key Points Question What is the prevalence of myocarditis in competitive athletes after COVID-19 infection, and how would different approaches to screening affect detection? Findings In this cohort study of 1597 US competitive collegiate athletes undergoing comprehensive cardiovascular testing, the prevalence of clinical myocarditis based on a symptom-based screening strategy was only 0.31%. Screening with cardiovascular magnetic resonance imaging increased the prevalence of clinical and subclinical myocarditis by a factor of 7.4 to 2.3%. Meaning These cardiac magnetic resonance imaging findings provide important data on the prevalence of clinical and subclinical myocarditis in college athletes recovering from symptomatic and asymptomatic COVID-19 infections., Importance Myocarditis is a leading cause of sudden death in competitive athletes. Myocardial inflammation is known to occur with SARS-CoV-2. Different screening approaches for detection of myocarditis have been reported. The Big Ten Conference requires comprehensive cardiac testing including cardiac magnetic resonance (CMR) imaging for all athletes with COVID-19, allowing comparison of screening approaches. Objective To determine the prevalence of myocarditis in athletes with COVID-19 and compare screening strategies for safe return to play. Design, Setting, and Participants Big Ten COVID-19 Cardiac Registry principal investigators were surveyed for aggregate observational data from March 1, 2020, through December 15, 2020, on athletes with COVID-19. For athletes with myocarditis, presence of cardiac symptoms and details of cardiac testing were recorded. Myocarditis was categorized as clinical or subclinical based on the presence of cardiac symptoms and CMR findings. Subclinical myocarditis classified as probable or possible myocarditis based on other testing abnormalities. Myocarditis prevalence across universities was determined. The utility of different screening strategies was evaluated. Exposures SARS-CoV-2 by polymerase chain reaction testing. Main Outcome and Measure Myocarditis via cardiovascular diagnostic testing. Results Representing 13 universities, cardiovascular testing was performed in 1597 athletes (964 men [60.4%]). Thirty-seven (including 27 men) were diagnosed with COVID-19 myocarditis (overall 2.3%; range per program, 0%-7.6%); 9 had clinical myocarditis and 28 had subclinical myocarditis. If cardiac testing was based on cardiac symptoms alone, only 5 athletes would have been detected (detected prevalence, 0.31%). Cardiac magnetic resonance imaging for all athletes yielded a 7.4-fold increase in detection of myocarditis (clinical and subclinical). Follow-up CMR imaging performed in 27 (73.0%) demonstrated resolution of T2 elevation in all (100%) and late gadolinium enhancement in 11 (40.7%). Conclusions and Relevance In this cohort study of 1597 US competitive athletes with CMR screening after COVID-19 infection, 37 athletes (2.3%) were diagnosed with clinical and subclinical myocarditis. Variability was observed in prevalence across universities, and testing protocols were closely tied to the detection of myocarditis. Variable ascertainment and unknown implications of CMR findings underscore the need for standardized timing and interpretation of cardiac testing. These unique CMR imaging data provide a more complete understanding of the prevalence of clinical and subclinical myocarditis in college athletes after COVID-19 infection. The role of CMR in routine screening for athletes safe return to play should be explored further.
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- 2021
20. Developmental programming for allergy: a secondary analysis of the Mothers, Omega-3, and Mental Health Study
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Romero, Vivian C., Somers, Emily C., Stolberg, Valerie, Clinton, Chelsea, Chensue, Stephen, Djuric, Zora, Berman, Deborah R., Treadwell, Marjorie C., Vahratian, Anjel M., and Mozurkewich, Ellen
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- 2013
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21. Global outbreak research: harmony not hegemony
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Akhvlediani, Tamuna, Ali, Syed M, Angus, Derek C, Arabi, Yaseen M, Ashraf, Sheharyar, Baillie, J Kenneth, Bakamutumaho, Barnabas, Beane, Abi, Bozza, Fernando, Brett, Stephen J, Bruzzone, Roberto, Carson, Gail, Castle, Lyndsey, Christian, Michael, Cobb, J Perren, Cummings, Matthew J, D'Ortenzio, Eric, de Jong, Menno D, Denis, Emmanuelle, Derde, LPG, Dobell, Emily, Dondorp, Arjen M, Dunning, Jake W, Everett, Dean, Farrar, Jeremy, Fowler, Rob, Gamage, Dilanthi, Gao, Zhancheng, Gomersall, Charles D, Gordon, Anthony C, Haniffa, Rashan, Hardwick, Hayley, Hashmi, Madiha, Hayat, Mohammad, Hayden, Frederick G, Ho, Antonia, Horby, Peter, Horby, Peter W, Jamieson, Nina, Jawad, Issrah, John, Marshall, Kennon, Kalynn, Khaskheli, Saleh, Khoo, Saye H, Lang, Trudie, Lee, James, Ling, Lowell, Marshall, John C, Memon, Mohammad I, Mentré, France, Merson, Laura, Moore, Sarah, Murthy, Srinivas, Nichol, Alistair, O'Donnell, Max R, Olliaro, Piero L, Olliaro, Piero, Openshaw, Peter J, Parke, Rachael, Pereira, Rui, Plotkin, Daniel, Pritchard, Mark, Rabindrarajan, Ebenezer, Ramakrishnan, Nagarajan, Richards, Toby, Ruiz-Palacios, Guillermo M, Russell, Clark D, Scott, Janet T, Semple, Malcolm G, Shindo, Nahoko, Sigfrid, Louise, Somers, Emily C, Taqi, Arshad, Turtle, Lance, Thevarajan, Irani, Tirupakuzhi Vijayaraghavan, Bharath Kumar, Udayanga, Ishara, van der Werf, Sylvie, Vatrinet, Renaud, Vecham, Pavan Kumar, Webb, Steve, Amuasi, John, Cevik, Muge, Fischer, William, and Fletcher, Tom
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- 2020
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22. Mercury levels in pregnant women, children, and seafood from Mexico City
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Basu, Niladri, Tutino, Rebecca, Zhang, Zhenzhen, Cantonwine, David E., Goodrich, Jaclyn M., Somers, Emily C., Rodriguez, Lauren, Schnaas, Lourdes, Solano, Maritsa, Mercado, Adriana, Peterson, Karen, Sánchez, Brisa N., Hernández-Avila, Mauricio, Hu, Howard, and Téllez-Rojo, Martha Maria
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- 2014
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23. Population-Based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program
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Somers, Emily C., Marder, Wendy, Cagnoli, Patricia, Lewis, Emily E., DeGuire, Peter, Gordon, Caroline, Helmick, Charles G., Wang, Lu, Wing, Jeffrey J., Dhar, Patricia J., Leisen, James, Shaltis, Diane, and McCune, Joseph W.
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- 2014
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24. The prevalence and impact of pre-existing sleep disorder diagnoses and objective sleep parameters in patients hospitalized for COVID-19
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Goldstein, Cathy A., primary, Rizvydeen, Muneer, additional, Conroy, Deirdre A., additional, O’Brien, Louise M., additional, Gupta, Gita, additional, Somers, Emily C., additional, Sharma, Pratima, additional, Golob, Jonathan L., additional, Troost, Jonathan P., additional, and Burgess, Helen J., additional
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- 2021
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25. Prevalence of Systemic Lupus Erythematosus in the United States: Estimates From a Meta‐Analysis of the Centers for Disease Control and Prevention National Lupus Registries
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Izmirly, Peter M., primary, Parton, Hilary, additional, Wang, Lu, additional, McCune, W. Joseph, additional, Lim, S. Sam, additional, Drenkard, Cristina, additional, Ferucci, Elizabeth D., additional, Dall'Era, Maria, additional, Gordon, Caroline, additional, Helmick, Charles G., additional, and Somers, Emily C., additional
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- 2021
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26. Interferon-α promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis
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Denny, Michael F., Thacker, Seth, Mehta, Hemal, Somers, Emily C., Dodick, Todd, Barrat, Franck J., McCune, W. Joseph, and Kaplan, Mariana J.
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- 2007
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27. Corrigendum to “Pregnancy and autoimmune connective tissue diseaes” [Best Practice & Research Clinical Rheumatology 30 (2016) 63–80]
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Marder, Wendy, primary, Littlejohn, Emily A., additional, and Somers, Emily C., additional
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- 2020
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28. Parental history of lupus and rheumatoid arthritis and risk in offspring in a nationwide cohort study: does sex matter?
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Somers, Emily C, Antonsen, Sussie, Pedersen, Lars, and Sørensen, Henrik Toft
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- 2013
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29. Measurement of cell-bound complement activation products enhances diagnostic performance in systemic lupus erythematosus
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Kalunian, Kenneth C., Chatham, Winn W., Massarotti, Elena M., Reyes-Thomas, Joyce, Harris, Cole, Furie, Richard A., Chitkara, Puja, Putterman, Chaim, Gross, Rachel L., Somers, Emily C., Kirou, Kyriakos A., Ramsey-Goldman, Rosalind, Hsieh, Christine, Buyon, Jill P., Dervieux, Thierry, and Weinstein, Arthur
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- 2012
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30. Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients
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Webb, Ryan, Kelly, Jennifer A, Somers, Emily C, Hughes, Travis, Kaufman, Kenneth M, Sanchez, Elena, Nath, Swapan K, Bruner, Gail, Alarcón-Riquelme, Marta E, Gilkeson, Gary S, Kamen, Diane L, Richardson, Bruce C, Harley, John B, and Sawalha, Amr H
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- 2011
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31. COVID-19 Outcomes Among Solid Organ Transplant Recipients: A Case-control Study
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Sharma, Pratima, primary, Chen, Vincent, additional, Fung, Christopher M., additional, Troost, Jonathan P., additional, Patel, Vaiibhav N., additional, Combs, Michael, additional, Norman, Silas, additional, Garg, Puneet, additional, Colvin, Monica, additional, Aaronson, Keith, additional, Sonnenday, Christopher J., additional, Golob, Jonathan L., additional, Somers, Emily C., additional, and Doshi, Mona M., additional
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- 2020
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32. Tocilizumab for Treatment of Mechanically Ventilated Patients With COVID-19
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Somers, Emily C, primary, Eschenauer, Gregory A, additional, Troost, Jonathan P, additional, Golob, Jonathan L, additional, Gandhi, Tejal N, additional, Wang, Lu, additional, Zhou, Nina, additional, Petty, Lindsay A, additional, Baang, Ji Hoon, additional, Dillman, Nicholas O, additional, Frame, David, additional, Gregg, Kevin S, additional, Kaul, Dan R, additional, Nagel, Jerod, additional, Patel, Twisha S, additional, Zhou, Shiwei, additional, Lauring, Adam S, additional, Hanauer, David A, additional, Martin, Emily, additional, Sharma, Pratima, additional, Fung, Christopher M, additional, and Pogue, Jason M, additional
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- 2020
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33. Dietary Omega Polyunsaturated Fatty Acid Intake and Patient‐Reported Outcomes in Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program
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Charoenwoodhipong, Prae, primary, Harlow, Sioban D., additional, Marder, Wendy, additional, Hassett, Afton L., additional, McCune, W. Joseph, additional, Gordon, Caroline, additional, Helmick, Charles G., additional, Barbour, Kamil E., additional, Wang, Lu, additional, Mancuso, Peter, additional, Somers, Emily C., additional, and Zick, Suzanna M., additional
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- 2020
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34. Pregnancy and autoimmune diseases
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Somers, Emily C., primary
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- 2020
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35. 2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases
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Sammaritano, Lisa R., primary, Bermas, Bonnie L., additional, Chakravarty, Eliza E., additional, Chambers, Christina, additional, Clowse, Megan E. B., additional, Lockshin, Michael D., additional, Marder, Wendy, additional, Guyatt, Gordon, additional, Branch, D. Ware, additional, Buyon, Jill, additional, Christopher‐Stine, Lisa, additional, Crow‐Hercher, Rachelle, additional, Cush, John, additional, Druzin, Maurice, additional, Kavanaugh, Arthur, additional, Laskin, Carl A., additional, Plante, Lauren, additional, Salmon, Jane, additional, Simard, Julia, additional, Somers, Emily C., additional, Steen, Virginia, additional, Tedeschi, Sara K., additional, Vinet, Evelyne, additional, White, C. Whitney, additional, Yazdany, Jinoos, additional, Barbhaiya, Medha, additional, Bettendorf, Brittany, additional, Eudy, Amanda, additional, Jayatilleke, Arundathi, additional, Shah, Amit Aakash, additional, Sullivan, Nancy, additional, Tarter, Laura L., additional, Birru Talabi, Mehret, additional, Turgunbaev, Marat, additional, Turner, Amy, additional, and D'Anci, Kristen E., additional
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- 2020
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36. Do selected drugs increase the risk of lupus? A matched case-control study
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Schoonen, W. Marieke, Thomas, Sara L., Somers, Emily C., Smeeth, Liam, Kim, Joseph, Evans, Stephen, and Hall, Andrew J.
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- 2010
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37. Population-Based Lupus Registries: Advancing Our Epidemiologic Understanding
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Lim, Sam S., Drenkard, Cristina, McCune, Joseph W., Helmick, Charles G., Gordon, Caroline, DeGuire, Peter, Bayakly, Rana, and Somers, Emily C.
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- 2009
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38. Are Individuals With an Autoimmune Disease at Higher Risk of a Second Autoimmune Disorder?
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Somers, Emily C., Thomas, Sara L., Smeeth, Liam, and Hall, Andrew J.
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- 2009
39. Co-Existence of Autoimmune Diseases within Individuals: 111.
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Somers, Emily C, Thomas, Sara L, Smeeth, Liam, and Hall, Andrew J
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- 2007
40. Incidence of Systemic Lupus Erythematosus in the United Kingdom, 1990–1999
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SOMERS, EMILY C., THOMAS, SARA L., SMEETH, LIAM, SCHOONEN, W. MARIEKE, and HALL, ANDREW J.
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- 2007
41. Presentation of Arthritogenic Peptide to Antigen-Specific T Cells by Fibroblast-Like Synoviocytes
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Tran, Chinh N., Davis, Michael J., Tesmer, Laura A., Endres, Judith L., Motyl, Christopher D., Smuda, Craig, Somers, Emily C., Chung, Kevin C., Urquhart, Andrew G., Lundy, Steven K., Kovats, Susan, and Fox, David A.
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- 2007
42. Use of a Gonadotropin-Releasing Hormone Analog for Protection Against Premature Ovarian Failure During Cyclophosphamide Therapy in Women With Severe Lupus
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Somers, Emily C., Marder, Wendy, Christman, Gregory M., Ognenovski, Vladimir, and McCune, W. Joseph
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- 2005
43. Plasminogen Activator Inhibitor-1 Is Associated with Impaired Endothelial Function in Women with Systemic Lupus Erythematosus
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SOMERS, EMILY C., MARDER, WENDY, KAPLAN, MARIANA J., BROOK, ROBERT D., and McCUNE, W JOSEPH
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- 2005
44. Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity
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Rajagopalan, Sanjay, Somers, Emily C., Brook, Robert D., Kehrer, Christine, Pfenninger, Dana, Lewis, Emily, Chakrabarti, Anjan, Richardson, Bruce C., Shelden, Eric, McCune, W. Joseph, and Kaplan, Mariana J.
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- 2004
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45. Mercury exposure and antinuclear antibodies among females of reproductive age in the United States: NHANES
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Somers, Emily C., Ganser, Martha A., Warren, Jeffrey S., Basu, Niladri, Wang, Lu, Zick, Suzanna M., and Park, Sung Kyun
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Women -- Health aspects ,Antinuclear antibodies ,Mercury -- Health aspects ,Autoimmune diseases ,Environmental issues ,Health - Abstract
BACKGROUND: Immune deregulation associated with mercury has been suggested, although data in the general population are lacking. Chronic exposure to low levels of methylmercury (organic) and inorganic mercury is common, such as through fish consumption and dental amalgams. OBJECTIVE: We examined associations between mercury biomarkers and antinuclear antibody (ANA) positivity and titer strength. METHODS: Among females 16-49 years of age (n = 1,352) from the National Health and Nutrition Examination Survey (NHANES) 1999-2004, we examined cross-sectional associations between mercury and ANAs (indirect immunofluorescence; cutoff > 1:80). Three biomarkers of mercury exposure were used: hair (available 1999-2000) and total blood (1999-2004) predominantly represented methylmercury, and urine (1999-2002) represented inorganic mercury. Survey statistics were used. Multivariable modeling adjusted for several covariates, including age and omega-3 fatty acids. RESULTS: Sixteen percent of females were ANA positive; 96% of ANA positives had a nuclear speckled staining pattern. Geometric mean (geometric SD) mercury concentrations were 0.22 (0.03) ppm in hair, 0.92 (0.05) µg/L blood, and 0.62 (0.04) µg/L urine. Hair and blood, but not urinary, mercury were associated with ANA positivity (sample sizes 452, 1,352, and 804, respectively), after adjusting for confounders: for hair, odds ratio (OR) = 4.10 (95% CI: 1.66, 10.13); for blood, OR = 2.32 (95% CI: 1.07, 5.03) comparing highest versus lowest quantiles. Magnitudes of association were strongest for high-titer (≥ 1:1,280) ANA: hair, OR = 11.41 (95% CI: 1.60, 81.23); blood, OR = 5.93 (95% CI: 1.57, 22.47). CONCLUSIONS: Methylmercury, at low levels generally considered safe, was associated with subclinical autoimmunity among reproductive-age females. Autoantibodies may predate clinical disease by years; thus, methylmercury exposure may be relevant to future autoimmune disease risk., Introduction Autoimmune disorders, although individually rare, are collectively estimated to afflict 7.6-9.4% of Americans (Cooper et al. 2009) and are among the 10 leading causes of death among women (Thomas [...]
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- 2015
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46. USE OF LEUPROLIDE ACETATE FOR OVARIAN PROTECTION DURING CYCLOPHOSPHAMIDE THERAPY OF WOMEN WITH SEVERE SLE: A CASE CONTROL STUDY.
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McCune, W Joseph, Somers, Emily C, Ognenovski, Vladimir, and Christman, Gregory
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- 2001
47. Tocilizumab for Treatment of Mechanically Ventilated Patients With COVID-19.
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Somers, Emily C, Eschenauer, Gregory A, Troost, Jonathan P, Golob, Jonathan L, Gandhi, Tejal N, Wang, Lu, Zhou, Nina, Petty, Lindsay A, Baang, Ji Hoon, Dillman, Nicholas O, Frame, David, Gregg, Kevin S, Kaul, Dan R, Nagel, Jerod, Patel, Twisha S, Zhou, Shiwei, Lauring, Adam S, Hanauer, David A, Martin, Emily, and Sharma, Pratima
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INTERLEUKINS , *STATISTICS , *COVID-19 , *CONFIDENCE intervals , *TOCILIZUMAB , *MECHANICAL ventilators , *MULTIVARIATE analysis , *PATIENTS , *ARTIFICIAL respiration , *TREATMENT effectiveness , *DESCRIPTIVE statistics , *KAPLAN-Meier estimator , *DATA analysis software , *ODDS ratio , *PATIENT safety , *SECONDARY analysis - Abstract
Background Severe coronavirus disease 2019 (COVID-19) can manifest in rapid decompensation and respiratory failure with elevated inflammatory markers, consistent with cytokine release syndrome for which IL-6 blockade is an approved treatment. Methods We assessed effectiveness and safety of IL-6 blockade with tocilizumab in a single-center cohort of patients with COVID-19 requiring mechanical ventilation. The primary endpoint was survival probability postintubation; secondary analyses included an ordinal illness severity scale integrating superinfections. Outcomes in patients who received tocilizumab compared with tocilizumab-untreated controls were evaluated using multivariable Cox regression with propensity score inverse probability of treatment weighting (IPTW). Results 154 patients were included, of whom 78 received tocilizumab and 76 did not. Median follow-up was 47 days (range, 28–67). Baseline characteristics were similar between groups, although tocilizumab-treated patients were younger (mean: 55 vs 60 years), less likely to have chronic pulmonary disease (10% vs 28%), and had lower D-dimer values at time of intubation (median: 2.4 vs 6.5 mg/dL). In IPTW-adjusted models, tocilizumab was associated with a 45% reduction in hazard of death (HR,.55; 95% CI,.33–.90) and improved status on the ordinal outcome scale [OR per 1-level increase,.58;.36–.94). Although tocilizumab was associated with an increased proportion of patients with superinfections (54% vs 26%; P < .001), there was no difference in 28-day case fatality rate among tocilizumab-treated patients with versus without superinfection (22% vs 15%; P = .42). Staphylococcus aureus accounted for ~50% of bacterial pneumonia. Conclusions In this cohort of mechanically ventilated COVID-19 patients, tocilizumab was associated with lower mortality despite higher superinfection occurrence. [ABSTRACT FROM AUTHOR]
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- 2021
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48. 2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.
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Sammaritano, Lisa R., Bermas, Bonnie L., Chakravarty, Eliza E., Chambers, Christina, Clowse, Megan E. B., Lockshin, Michael D., Marder, Wendy, Guyatt, Gordon, Branch, D. Ware, Buyon, Jill, Christopher‐Stine, Lisa, Crow‐Hercher, Rachelle, Cush, John, Druzin, Maurice, Kavanaugh, Arthur, Laskin, Carl A., Plante, Lauren, Salmon, Jane, Simard, Julia, and Somers, Emily C.
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UNIVERSITIES & colleges ,CONTRACEPTION ,HORMONES ,HUMAN reproductive technology ,MEDICAL protocols ,MUSCULOSKELETAL system diseases ,RHEUMATISM ,THERAPEUTICS ,REPRODUCTIVE health ,FERTILITY preservation - Abstract
Objective: To develop an evidence‐based guideline on contraception, assisted reproductive technologies (ART), fertility preservation with gonadotoxic therapy, use of menopausal hormone replacement therapy (HRT), pregnancy assessment and management, and medication use in patients with rheumatic and musculoskeletal disease (RMD). Methods: We conducted a systematic review of evidence relating to contraception, ART, fertility preservation, HRT, pregnancy and lactation, and medication use in RMD populations, using Grading of Recommendations Assessment, Development and Evaluation methodology to rate the quality of evidence and a group consensus process to determine final recommendations and grade their strength (conditional or strong). Good practice statements were agreed upon when indirect evidence was sufficiently compelling that a formal vote was unnecessary. Results: This American College of Rheumatology guideline provides 12 ungraded good practice statements and 131 graded recommendations for reproductive health care in RMD patients. These recommendations are intended to guide care for all patients with RMD, except where indicated as being specific for patients with systemic lupus erythematosus, those positive for antiphospholipid antibody, and/or those positive for anti‐Ro/SSA and/or anti‐La/SSB antibodies. Recommendations and good practice statements support several guiding principles: use of safe and effective contraception to prevent unplanned pregnancy, pre‐pregnancy counseling to encourage conception during periods of disease quiescence and while receiving pregnancy‐compatible medications, and ongoing physician‐patient discussion with obstetrics/gynecology collaboration for all reproductive health issues, given the overall low level of available evidence that relates specifically to RMD. Conclusion: This guideline provides evidence‐based recommendations developed and reviewed by panels of experts and RMD patients. Many recommendations are conditional, reflecting a lack of data or low‐level data. We intend that this guideline be used to inform a shared decision‐making process between patients and their physicians on issues related to reproductive health that incorporates patients' values, preferences, and comorbidities. [ABSTRACT FROM AUTHOR]
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- 2020
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49. Infertility – Prevention and Management
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Somers, Emily C., primary and Marder, Wendy, additional
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- 2017
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50. CE-51 Utility of linkage of a surveillance registry to state birth records for categorization of race and ethnicity: michigan lupus epidemiology & surveillance (miles) program
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Somers, Emily C, primary, Marder, Wendy, additional, Ganser, Martha, additional, DeGuire, Peter, additional, Helmick, Charles G, additional, Gordon, Caroline, additional, Wang, Lu, additional, Lewis, Emily E, additional, and McCune, W Joseph, additional
- Published
- 2016
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