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2. Acceptance and Commitment Therapy plus usual care for improving quality of life in people with motor neuron disease (COMMEND): a multicentre, parallel, randomised controlled trial in the UK

Author

Andreou, Penny, Androulaki-Korakaki, Dynameni, Blakeley, Claire, Bridges, Gary, Campbell, Iain, Davenport, Brittany, Dee, Annily, Drewry, Nicola, Flood, John, Fox, Annemieke, Girling, Melissa, Glew, Ruth, Hartley, Nick, Hocking, Sian, Howell, Mark, Keetharuth, Anju, Makin, Selina, Marsh, Jessica, Mayberry, Emily, McDonald, Alexa, McPartland, Roy, Meldrum, Steven, Mobley, Amanda, Murphy, Donnchadh, O'Brien, Marie Claire, Oliver, Mark, Patel, Darshna, Phipps, Emma, Read, Jessica, Roberts, Rhys, Rooney, Natasha, Smith, Carla, Statham, Jo, Thompson, Cara, Varma, Priya, Walker, Anne Marie, Waterhouse, Simon, Gould, Rebecca L, McDermott, Christopher J, Thompson, Benjamin J, Rawlinson, Charlotte V, Bursnall, Matt, Bradburn, Mike, Kumar, Pavithra, Turton, Emily J, White, David A, Serfaty, Marc A, Graham, Christopher D, McCracken, Lance M, Goldstein, Laura H, Al-Chalabi, Ammar, Orrell, Richard W, Williams, Tim, Noad, Rupert, Baker, Idris, Faull, Christina, Lambert, Thomas, Chhetri, Suresh K, Ealing, John, Hanratty, Anthony, Radunovic, Aleksandar, Gunawardana, Nushan, Meadows, Gail, Gorrie, George H, Young, Tracey, Lawrence, Vanessa, Cooper, Cindy, Shaw, Pamela J, and Howard, Robert J

Published
2024
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4. A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol

Author

Gould, Rebecca L., Thompson, Benjamin J., Rawlinson, Charlotte, Kumar, Pavithra, White, David, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., Bursnall, Matt, Bradburn, Mike, Young, Tracey, Howard, Robert J., Al-Chalabi, Ammar, Goldstein, Laura H., Lawrence, Vanessa, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Published
2022
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6. Acceptance and Commitment Therapy plus usual care for improving quality of life in people with motor neuron disease (COMMEND): a multicentre, parallel, randomised controlled trial in the UK

Author

Gould, Rebecca L, primary, McDermott, Christopher J, additional, Thompson, Benjamin J, additional, Rawlinson, Charlotte V, additional, Bursnall, Matt, additional, Bradburn, Mike, additional, Kumar, Pavithra, additional, Turton, Emily J, additional, White, David A, additional, Serfaty, Marc A, additional, Graham, Christopher D, additional, McCracken, Lance M, additional, Goldstein, Laura H, additional, Al-Chalabi, Ammar, additional, Orrell, Richard W, additional, Williams, Tim, additional, Noad, Rupert, additional, Baker, Idris, additional, Faull, Christina, additional, Lambert, Thomas, additional, Chhetri, Suresh K, additional, Ealing, John, additional, Hanratty, Anthony, additional, Radunovic, Aleksandar, additional, Gunawardana, Nushan, additional, Meadows, Gail, additional, Gorrie, George H, additional, Young, Tracey, additional, Lawrence, Vanessa, additional, Cooper, Cindy, additional, Shaw, Pamela J, additional, Howard, Robert J, additional, Andreou, Penny, additional, Androulaki-Korakaki, Dynameni, additional, Blakeley, Claire, additional, Bridges, Gary, additional, Campbell, Iain, additional, Davenport, Brittany, additional, Dee, Annily, additional, Drewry, Nicola, additional, Flood, John, additional, Fox, Annemieke, additional, Girling, Melissa, additional, Glew, Ruth, additional, Hartley, Nick, additional, Hocking, Sian, additional, Howell, Mark, additional, Keetharuth, Anju, additional, Makin, Selina, additional, Marsh, Jessica, additional, Mayberry, Emily, additional, McDonald, Alexa, additional, McPartland, Roy, additional, Meldrum, Steven, additional, Mobley, Amanda, additional, Murphy, Donnchadh, additional, O'Brien, Marie Claire, additional, Oliver, Mark, additional, Patel, Darshna, additional, Phipps, Emma, additional, Read, Jessica, additional, Roberts, Rhys, additional, Rooney, Natasha, additional, Smith, Carla, additional, Statham, Jo, additional, Thompson, Cara, additional, Varma, Priya, additional, Walker, Anne Marie, additional, and Waterhouse, Simon, additional

Published
2024
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8. Cost‐effectiveness of acceptance and commitment therapy for people living with motor neuron disease, and their health‐related quality of life.

Author

Keetharuth, Anju D., Gould, Rebecca L., McDermott, Christopher J., Thompson, Benjamin J., Rawlinson, Charlotte, Bradburn, Mike, Bursnall, Matt, Kumar, Pavithra, Turton, Emily J., Tappenden, Paul, White, David, Howard, Robert J., Serfaty, Marc A., McCracken, Lance M., Graham, Christopher D., Al‐Chalabi, Ammar, Goldstein, Laura H., Lawrence, Vanessa, Cooper, Cindy, and Young, Tracey

Subjects
ACCEPTANCE & commitment therapy, MOTOR neuron diseases, QUALITY of life, QUALITY-adjusted life years, COST effectiveness
Abstract

Background: Given the degenerative nature of the condition, people living with motor neuron disease (MND) experience high levels of psychological distress. The purpose of this research was to investigate the cost‐effectiveness of acceptance and commitment therapy (ACT), adapted for the specific needs of this population, for improving quality of life. Methods: A trial‐based cost–utility analysis over a 9‐month period was conducted comparing ACT plus usual care (n = 97) versus usual care alone (n = 94) from the perspective of the National Health Service. In the primary analysis, quality‐adjusted life years (QALYs) were computed using health utilities generated from the EQ‐5D‐5L questionnaire. Sensitivity analyses and subgroup analyses were also carried out. Results: Difference in costs was statistically significant between the two arms, driven mainly by the intervention costs. Effects measured by EQ‐5D‐5L were not statistically significantly different between the two arms. The incremental cost‐effectiveness was above the £20,000 to £30,000 per QALY gained threshold used in the UK. However, the difference in effects was statistically significant when measured by the McGill Quality of Life‐Revised (MQOL‐R) questionnaire. The intervention was cost‐effective in a subgroup experiencing medium deterioration in motor neuron symptoms. Conclusions: Despite the intervention being cost‐ineffective in the primary analysis, the significant difference in the effects measured by MQOL‐R, the low costs of the intervention, the results in the subgroup analysis, and the fact that ACT was shown to improve the quality of life for people living with MND, suggest that ACT could be incorporated into MND clinical services. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Psychological Distress and Interventions for Older Victims of Crime: A Systematic Review.

Author

Satchell, Jessica, Craston, Tabitha, Drennan, Vari M., Billings, Jo, and Serfaty, Marc

Subjects
PSYCHOLOGY information storage & retrieval systems, CINAHL database, EMBARRASSMENT, MEDICAL information storage & retrieval systems, CONFIDENCE intervals, CONFIDENCE, TRAFFIC accidents, SOCIAL support, SYSTEMATIC reviews, SELF-perception, POST-traumatic stress disorder, MENTAL health, FEAR, PSYCHOEDUCATION, CRIME victims, SOCIAL isolation, MENTAL depression, DESCRIPTIVE statistics, INDEPENDENT living, RESEARCH funding, ANXIETY, MEDLINE, THEMATIC analysis, SHAME, PSYCHOLOGICAL distress, PSYCHOTHERAPY, BEHAVIOR modification, COGNITIVE therapy, TRUST, CRISIS intervention (Mental health services), NURSING interventions, OLD age
Abstract

We aimed to conduct the first systematic narrative review and quality appraisal of existing evidence on the psychological consequences of crime in older victims in the community and psychological interventions. We searched five databases to identify all peer-reviewed literature published in English on psychological impact and/or interventions for older crime victims and quality appraised these using the Mixed-Methods Appraisal Tool, following Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines (Prospero: CRD42019140137). Evidence from included studies were narratively synthesized, along with their strengths and limitations. We found 20 studies on psychological distress in older victims, four of which included interventions. From these, we identified 30 different impacts including symptoms of anxiety, depression, post-traumatic stress disorder, emotions including humiliation and self-blame, and behavioral changes. Only feasibility interventions have been published, although promising results were reported for cognitive-behavioral informed treatments for depression and anxiety. Studies were wide-ranging in aims, crimes included, and outcomes used. Recommendations for improving the evidence-base and to raise the profile of this neglected population have been provided. [ABSTRACT FROM AUTHOR]

Published
2023
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16. Acceptance and Commitment Therapy for people living with motor neuron disease : an uncontrolled feasibility study

Author

Gould, Rebecca, Rawlinson, Charlotte K., Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah A., Serfaty, Marc, Graham, Christopher, McCracken, Lance, White, David, Howard, Robert, Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh, Noad, Rupert, Radunovic, Aleksandar, Williams, Tim J., Young, Carolyn J., Dick, David, Lawrence, Vanessa, Goldstein, Laura, Young, Tracey, Ealing, John, McLeod, Hamish, Williams, Nicola, Weatherly, Helen, Cave, Richard, Chiwera, Theresa, Pagnini, Francesco, Cooper, Cindy, Shaw, Pamela, McDermott, Christopher, Group, COMMEND Collaboration, Gould, Rebecca, Rawlinson, Charlotte K., Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah A., Serfaty, Marc, Graham, Christopher, McCracken, Lance, White, David, Howard, Robert, Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh, Noad, Rupert, Radunovic, Aleksandar, Williams, Tim J., Young, Carolyn J., Dick, David, Lawrence, Vanessa, Goldstein, Laura, Young, Tracey, Ealing, John, McLeod, Hamish, Williams, Nicola, Weatherly, Helen, Cave, Richard, Chiwera, Theresa, Pagnini, Francesco, Cooper, Cindy, Shaw, Pamela, McDermott, Christopher, and Group, COMMEND Collaboration

Abstract

Background: Motor neuron disease (MND) is a fatal, progressive neurodegenerative disease that causes progressive weakening and wasting of limb, bulbar, thoracic and abdominal muscles. Clear evidence-based guidance on how psychological distress should be managed in people living with MND (plwMND) is lacking. Acceptance and Commitment Therapy (ACT) is a form of psychological therapy that may be particularly suitable for this population. However, to the authors' knowledge, no study to date has evaluated ACT for plwMND. Consequently, the primary aim of this uncontrolled feasibility study was to examine the feasibility and acceptability of ACT for improving the psychological health of plwMND. Methods: PlwMND aged >= 18 years were recruited from 10 UK MND Care Centres/Clinics. Participants received up to 8 one-to-one ACT sessions, developed specifically for plwMND, plus usual care. Co-primary feasibility and acceptability outcomes were uptake (>= 80% of the target sample [N = 28] recruited) and initial engagement with the intervention (>= 70% completing >= 2 sessions). Secondary outcomes included measures of quality of life, anxiety, depression, disease-related functioning, health status and psychological flexibility in plwMND and quality of life and burden in caregivers. Outcomes were assessed at baseline and 6 months. Results: Both a priori indicators of success were met: 29 plwMND (104%) were recruited and 76% (22/29) attended >= 2 sessions. Attrition at 6-months was higher than anticipated (8/29, 28%), but only two dropouts were due to lack of acceptability of the intervention. Acceptability was further supported by good satisfaction with therapy and session attendance. Data were possibly suggestive of small improvements in anxiety and psychological quality of life from baseline to 6 months in plwMND, despite a small but expected deterioration in disease-related functioning and health status. Conclusions: There was good evidence of acceptability and fea

Published
2023
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18. Additional file 4 of Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study

Author

Gould, Rebecca L., Rawlinson, Charlotte, Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., White, David, Howard, Robert J., Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh K., Noad, Rupert, Radunovic, Aleksandar, Williams, Tim, Young, Carolyn A., Dick, David, Lawrence, Vanessa, Goldstein, Laura H., Young, Tracey, Ealing, John, McLeod, Hamish, Williams, Nicola, Weatherly, Helen, Cave, Richard, Chiwera, Theresa, Pagnini, Francesco, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 4. Psychologically inflexible processes and their psychologically flexible counterparts, with examples relevant to plwMND.

Published
2023
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19. Additional file 3 of Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study

Author

Gould, Rebecca L., Rawlinson, Charlotte, Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., White, David, Howard, Robert J., Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh K., Noad, Rupert, Radunovic, Aleksandar, Williams, Tim, Young, Carolyn A., Dick, David, Lawrence, Vanessa, Goldstein, Laura H., Young, Tracey, Ealing, John, McLeod, Hamish, Williams, Nicola, Weatherly, Helen, Cave, Richard, Chiwera, Theresa, Pagnini, Francesco, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 3. Information about baseline measures and outcome measures.

Published
2023
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20. Additional file 1 of Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study

Author

Gould, Rebecca L., Rawlinson, Charlotte, Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., White, David, Howard, Robert J., Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh K., Noad, Rupert, Radunovic, Aleksandar, Williams, Tim, Young, Carolyn A., Dick, David, Lawrence, Vanessa, Goldstein, Laura H., Young, Tracey, Ealing, John, McLeod, Hamish, Williams, Nicola, Weatherly, Helen, Cave, Richard, Chiwera, Theresa, Pagnini, Francesco, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 1. The consolidated standards of reporting trials (CONSORT) checklist (extension for randomised pilot or feasibility trials).

Published
2023
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21. Additional file 2 of Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study

Author

Gould, Rebecca L., Rawlinson, Charlotte, Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., White, David, Howard, Robert J., Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh K., Noad, Rupert, Radunovic, Aleksandar, Williams, Tim, Young, Carolyn A., Dick, David, Lawrence, Vanessa, Goldstein, Laura H., Young, Tracey, Ealing, John, McLeod, Hamish, Williams, Nicola, Weatherly, Helen, Cave, Richard, Chiwera, Theresa, Pagnini, Francesco, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 2. The template for intervention description and replication (TIDieR) checklist.

Published
2023
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24. Acceptance and Commitment Therapy for people living with motor neuron disease: an uncontrolled feasibility study.

Author

Gould, Rebecca L., Rawlinson, Charlotte, Thompson, Ben, Weeks, Kirsty, Gossage-Worrall, Rebecca, Cantrill, Hannah, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., White, David, Howard, Robert J., Bursnall, Matt, Bradburn, Mike, Al-Chalabi, Ammar, Orrell, Richard, Chhetri, Suresh K., Noad, Rupert, Radunovic, Aleksandar, Williams, Tim, and Young, Carolyn A.

Subjects
ACCEPTANCE & commitment therapy, MOTOR neuron diseases, PSYCHOTHERAPY, ADAPTABILITY (Personality), FEASIBILITY studies, ABDOMINAL muscles
Abstract

Background: Motor neuron disease (MND) is a fatal, progressive neurodegenerative disease that causes progressive weakening and wasting of limb, bulbar, thoracic and abdominal muscles. Clear evidence-based guidance on how psychological distress should be managed in people living with MND (plwMND) is lacking. Acceptance and Commitment Therapy (ACT) is a form of psychological therapy that may be particularly suitable for this population. However, to the authors' knowledge, no study to date has evaluated ACT for plwMND. Consequently, the primary aim of this uncontrolled feasibility study was to examine the feasibility and acceptability of ACT for improving the psychological health of plwMND. Methods: PlwMND aged ≥ 18 years were recruited from 10 UK MND Care Centres/Clinics. Participants received up to 8 one-to-one ACT sessions, developed specifically for plwMND, plus usual care. Co-primary feasibility and acceptability outcomes were uptake (≥ 80% of the target sample [N = 28] recruited) and initial engagement with the intervention (≥ 70% completing ≥ 2 sessions). Secondary outcomes included measures of quality of life, anxiety, depression, disease-related functioning, health status and psychological flexibility in plwMND and quality of life and burden in caregivers. Outcomes were assessed at baseline and 6 months. Results: Both a priori indicators of success were met: 29 plwMND (104%) were recruited and 76% (22/29) attended ≥ 2 sessions. Attrition at 6-months was higher than anticipated (8/29, 28%), but only two dropouts were due to lack of acceptability of the intervention. Acceptability was further supported by good satisfaction with therapy and session attendance. Data were possibly suggestive of small improvements in anxiety and psychological quality of life from baseline to 6 months in plwMND, despite a small but expected deterioration in disease-related functioning and health status. Conclusions: There was good evidence of acceptability and feasibility. Limitations included the lack of a control group and small sample size, which complicate interpretation of findings. A fully powered RCT to evaluate the clinical and cost-effectiveness of ACT for plwMND is underway. Trial registration: The study was pre-registered with the ISRCTN Registry (ISRCTN12655391). [ABSTRACT FROM AUTHOR]

Published
2023
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26. Additional file 4 of A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol

Author

Gould, Rebecca L., Thompson, Benjamin J., Rawlinson, Charlotte, Kumar, Pavithra, White, David, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., Bursnall, Matt, Bradburn, Mike, Young, Tracey, Howard, Robert J., Al-Chalabi, Ammar, Goldstein, Laura H., Lawrence, Vanessa, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 4. Example consent form.

Published
2022
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27. Additional file 1 of A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol

Author

Gould, Rebecca L., Thompson, Benjamin J., Rawlinson, Charlotte, Kumar, Pavithra, White, David, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., Bursnall, Matt, Bradburn, Mike, Young, Tracey, Howard, Robert J., Al-Chalabi, Ammar, Goldstein, Laura H., Lawrence, Vanessa, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 1. WHO Trial Registration Data Set.

Published
2022
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28. Additional file 2 of A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol

Author

Gould, Rebecca L., Thompson, Benjamin J., Rawlinson, Charlotte, Kumar, Pavithra, White, David, Serfaty, Marc A., Graham, Christopher D., McCracken, Lance M., Bursnall, Matt, Bradburn, Mike, Young, Tracey, Howard, Robert J., Al-Chalabi, Ammar, Goldstein, Laura H., Lawrence, Vanessa, Cooper, Cindy, Shaw, Pamela J., and McDermott, Christopher J.

Abstract

Additional file 2. Template for intervention description and replication (TIDieR) checklist.

Published
2022
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31. Acceptance and commitment therapy for older people with treatment-resistant generalised anxiety disorder: the FACTOID feasibility study

Author

Gould, Rebecca L, primary, Wetherell, Julie Loebach, additional, Serfaty, Marc A, additional, Kimona, Kate, additional, Lawrence, Vanessa, additional, Jones, Rebecca, additional, Livingston, Gill, additional, Wilkinson, Philip, additional, Walters, Kate, additional, Novere, Marie Le, additional, and Howard, Robert J, additional

Published
2021
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33. Clinical effectiveness of individual cognitive behavioral therapy for depressed older people in primary care: a randomized controlled trial

Author

Serfaty, Marc Antony, Haworth, Deborah, Blanchard, Martin, Buszewicz, Marta, Murad, Shahed, and King, Michael

Subjects
Cognitive therapy -- Patient outcomes, Cognitive therapy -- Demographic aspects, Cognitive therapy -- Research, Depression in old age -- Care and treatment, Depression in old age -- Patient outcomes, Depression in old age -- Research, Health, Psychology and mental health
Published
2009

34. Acceptance and commitment therapy for late-life treatment-resistant generalised anxiety disorder: a feasibility study

Author

Gould, Rebecca L, primary, Wetherell, Julie Loebach, additional, Kimona, Kate, additional, Serfaty, Marc A, additional, Jones, Rebecca, additional, Graham, Christopher D, additional, Lawrence, Vanessa, additional, Livingston, Gill, additional, Wilkinson, Philip, additional, Walters, Kate, additional, Le Novere, Marie, additional, Leroi, Iracema, additional, Barber, Robert, additional, Lee, Ellen, additional, Cook, Jo, additional, Wuthrich, Viviana M, additional, and Howard, Robert J, additional

Published
2021
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36. The clinical and cost-effectiveness of a Victim Improvement Package (VIP) for the reduction of chronic symptoms of depression or anxiety in older victims of common crime (the VIP trial): study protocol for a randomised controlled trial

Author

Serfaty, Marc, primary, Aspden, Trefor, additional, Satchell, Jessica, additional, Kessel, Anthony, additional, Laycock, Gloria, additional, Brewin, Chris R., additional, Buszewicz, Marta, additional, O’Keeffe, Aidan, additional, Hunter, Rachael, additional, Leavey, Gerard, additional, Cuming-Higgs, Jon, additional, Drennan, Vari, additional, Riveros, Monica, additional, Andrew, David, additional, and Blanchard, Martin, additional

Published
2020
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40. Needs and preferences for psychological interventions of people with motor neuron disease.

Author

Weeks, Kirsty R, Gould, Rebecca L, Mcdermott, Christopher, Lynch, Jessica, Goldstein, Laura H, Graham, Christopher D, McCracken, Lance, Serfaty, Marc, Howard, Robert, Al-Chalabi, Ammar, White, David, Bradburn, Mike, Young, Tracey, Cooper, Cindy, Shaw, Dame Pamela J, Lawrence, Vanessa, Weeks, Kirsty R, Gould, Rebecca L, Mcdermott, Christopher, Lynch, Jessica, Goldstein, Laura H, Graham, Christopher D, McCracken, Lance, Serfaty, Marc, Howard, Robert, Al-Chalabi, Ammar, White, David, Bradburn, Mike, Young, Tracey, Cooper, Cindy, Shaw, Dame Pamela J, and Lawrence, Vanessa

Abstract

Background: There is a lack of knowledge about what factors may impede or facilitate engagement in psychological interventions in people with motor neuron disease (pwMND) and how such interventions can be adapted to best meet the needs of this population. Objectives: To explore the needs and preferences of pwMND with respect to psychological interventions, and how best to adapt such interventions for pwMND. Methods: A series of semi-structured interviews (n = 22) and workshops (n = 3) were conducted with pwMND (n = 15), informal caregivers of pwMND (n = 10), and MND healthcare professionals (n = 12). These explored preferences and concerns that would need to be considered when delivering a psychological intervention for pwMND. Three areas were explored: (i) perceived factors that may hinder or facilitate pwMND engaging with psychological interventions; (ii) ways in which such interventions could be adapted to meet the individual needs of pwMND; and (iii) views regarding the main psychological issues that would need to be addressed. Workshops and interviews were audio recorded and transcribed and thematic analysis was used to inductively derive themes. Findings: Data could be classified within four overarching themes: unfamiliar territory; a series of losses; variability and difficulty meeting individual needs; and informal support. Conclusions: Flexibility, tailoring interventions to the individual needs of pwMND, and encouraging autonomy are key attributes for psychological interventions with pwMND. Psychological interventions such as Acceptance and Commitment Therapy (ACT) could be acceptable for pwMND if adapted to their specific needs.

Published
2019
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47. Needs and preferences for psychological interventions of people with motor neuron disease

Author

Weeks, Kirsty R., primary, Gould, Rebecca L., additional, Mcdermott, Christopher, additional, Lynch, Jessica, additional, Goldstein, Laura H., additional, Graham, Christopher D., additional, McCracken, Lance, additional, Serfaty, Marc, additional, Howard, Robert, additional, Al-Chalabi, Ammar, additional, White, David, additional, Bradburn, Mike, additional, Young, Tracey, additional, Cooper, Cindy, additional, Shaw, Dame Pamela J., additional, and Lawrence, Vanessa, additional

Published
2019
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48. Optimising the acceptability and feasibility of acceptance and commitment therapy for treatment-resistant generalised anxiety disorder in older adults

Author

Lawrence, Vanessa, primary, Kimona, Kate, additional, Howard, Robert J, additional, Serfaty, Marc A, additional, Wetherell, Julie Loebach, additional, Livingston, Gill, additional, Wilkinson, Philip, additional, Walters, Kate, additional, Jones, Rebecca, additional, Wuthrich, Viviana M, additional, and Gould, Rebecca L, additional

Published
2019
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