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In this study, X-ray photoelectron spectroscopy (XPS) was used to study chitosan-graphene oxide (chitosan-GO) incorporated with 4-(2-pyridylazo)resorcinol (PAR) and cadmium sulfide quantum dot (CdS QD) composite thin films for the potential optical sensing of cobalt ions (Co 2+ ). From the XPS results, it was confirmed that carbon, oxygen, and nitrogen elements existed on the PAR-chitosan-GO thin film, while for CdS QD-chitosan-GO, the existence of carbon, oxygen, cadmium, nitrogen, and sulfur were confirmed. Further deconvolution of each element using the Gaussian-Lorentzian curve fitting program revealed the sub-peak component of each element and hence the corresponding functional group was identified. Next, investigation using surface plasmon resonance (SPR) optical sensor proved that both chitosan-GO-based thin films were able to detect Co 2+ as low as 0.01 ppm for both composite thin films, while the PAR had the higher binding affinity. The interaction of the Co 2+ with the thin films was characterized again using XPS to confirm the functional group involved during the reaction. The XPS results proved that primary amino in the PAR-chitosan-GO thin film contributed more important role for the reaction with Co 2+ , as in agreement with the SPR results.

In this study, synthesis and characterization of chitosan/maghemite (Cs/Fe 2 O 3 ) composites thin film has been described. Its properties were characterized using Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM) and ultraviolet-visible spectroscopy (UV-Vis). FTIR confirmed the existence of Fe-O bond, C-N bond, C-C bond, C-O bond, O=C=O bond and O-H bond in Cs/Fe 2 O 3 thin film. The surface morphology of the thin film indicated the relatively smooth and homogenous thin film, and also confirmed the interaction of Fe 2 O 3 with the chitosan. Next, the UV-Vis result showed high absorbance value with an optical band gap of 4.013 eV. The incorporation of this Cs/Fe 2 O 3 thin film with an optical-based method, i.e., surface plasmon resonance spectroscopy showed positive response where mercury ion (Hg 2+ ) can be detected down to 0.01 ppm (49.9 nM). These results validate the potential of Cs/Fe 2 O 3 thin film for optical sensing applications in Hg 2+ detection.

Great efforts have been devoted to the invention of environmental sensors as the amount of water pollution has increased in recent decades. Chitosan, cellulose and nanocrystalline cellulose are examples of biopolymers that have been intensively studied due to their potential applications, particularly as sensors. Furthermore, the rapid use of conducting polymer materials as a sensing layer in environmental monitoring has also been developed. Thus, the incorporation of biopolymer and conducting polymer materials with various methods has shown promising potential with sensitively and selectively toward heavy metal ions. In this feature paper, selected recent and updated investigations are reviewed on biopolymer and conducting polymer-based materials in sensors aimed at the detection of heavy metal ions by optical methods. This review intends to provide sufficient evidence of the potential of polymer-based materials as sensing layers, and future outlooks are considered in developing surface plasmon resonance as an excellent and valid sensor for heavy metal ion detection.

In this study, the incorporation between gold modified-tyrosinase (Tyr) enzyme based graphene oxide (GO) thin film with surface plasmon resonance (SPR) technique has been developed for the detection of phenol. SPR signal for the thin film contacted with phenol solution was monitored using SPR technique. From the SPR curve, sensitivity, full width at half maximum (FWHM), detection accuracy (DA) and signal-to-noise ratio (SNR) have been analyzed. The sensor produces a linear response for phenol up to 100 µM with sensitivity of 0.00193° µM -1 . Next, it can be observed that deionized water has the lowest FWHM, with a value of 1.87° and also the highest value of DA. Besides, the SNR of the SPR signal was proportional to the phenol concentrations. Furthermore, the surface morphology of the modified thin film after exposed with phenol solution observed using atomic force microscopy showed a lot of sharp peaks compared to the image before in contact with phenol proved the interaction between the thin film and phenol.

In this study, the incorporation of surface plasmon resonance (SPR) spectroscopy with novel chitosan-graphene oxide/cadmium sulphide quantum dots (CdS QDs) active layer for cobalt ion (Co 2+ ) detection has been developed. The interaction of different Co 2+ concentrations with the novel modified active layer was monitored using the SPR technique. From the SPR results, detection range, sensitivity, full width at half maximum (FWHM), detection accuracy (DA) and signal-to-noise ratio (SNR) have been analysed. The results showed the detection range of this optical sensor was 0.01 to 10 ppm, and it was saturated for higher concentration of Co 2+ . The sensitivity obtained was 0.1188 ppm -1 for low concentration of Co 2+ ranged from 0.01 to 1 ppm. The FWHM and DA were consistent for all concentration of Co 2+ , while the SNR of the SPR signal increased with the Co 2+ concentration. The SPR angle shifts were also fitted using Langmuir, Freundlich and Sips (Langmuir-Freundlich) isotherm models, where Sips model fitted the best with the binding affinity of 0.939 ppm -1 . The results proved that the novel chitosan-graphene oxide/CdS QDs modified gold thin film can detect Co 2+ via SPR spectroscopy.

About 71% of the Earth's surface is covered with water. Human beings, animals, and plants need water in order to survive. Therefore, it is one of the most important substances that exist on Earth. However, most of the water resources nowadays are insufficiently clean, since they are contaminated with toxic metal ions due to the improper disposal of pollutants into water through industrial and agricultural activities. These toxic metal ions need to be detected as fast as possible so that the situation will not become more critical and cause more harm in the future. Since then, numerous sensing methods have been proposed, including chemical and optical sensors that aim to detect these toxic metal ions. All of the researchers compete with each other to build sensors with the lowest limit of detection and high sensitivity and selectivity. Graphene quantum dots (GQDs) have emerged as a highly potential sensing material to incorporate with the developed sensors due to the advantages of GQDs. Several recent studies showed that GQDs, functionalized GQDs, and their composites were able to enhance the optical detection of metal ions. The aim of this paper is to review the existing, latest, and updated studies on optical sensing applications of GQDs-based materials toward toxic metal ions and future developments of an excellent GQDs-based SPR sensor as an alternative toxic metal ion sensor.

The emergence of unintentional poisoning and uncontrolled vector diseases have contributed to sensor technologies development, leading to the more effective detection of diseases. In this study, we present the combination of graphene-based material with surface plasmon resonance technique. Two different graphene-based material sensor chips were prepared for rapid and quantitative detection of dengue virus (DENV) and cobalt ion (Co 2+ ) as an example of typical metal ions. As the fundamental concept of surface plasmon resonance (SPR) sensor that relies on the refractive index of the sensor chip surface, this research focused on the SPR signal when the DENV and Co 2+ interact with the graphene-based material sensor chip. The results demonstrated that the proposed sensor-based graphene layer was able to detect DENV and Co 2+ as low as 0.1 pM and 0.1 ppm respectively. Further details in the detection and quantification of analyte were also discussed in terms of sensitivity, affinity, and selectivity of the sensor.

Surface plasmon resonance (SPR) is a label-free optical spectroscopy that is widely used for biomolecular interaction analysis. In this work, SPR was used to characterize the binding properties of highly sensitive nanocrystalline cellulose-graphene oxide based nanocomposite (CTA-NCC/GO) towards nickel ion. The formation of CTA-NCC/GO nanocomposite has been confirmed by FT-IR. The SPR analysis result shows that the CTA-NCC/GO has high binding affinity towards Ni 2+ from 0.01 until 0.1 ppm with binding affinity constant of 1.620 × 10 3  M -1 . The sensitivity for the CTA-NCC/GO calculated was 1.509° ppm -1 . The full width at half maximum (FWHM), data accuracy (DA), and signal-to-noise ratio (SNR) have also been determined using the obtained SPR curve. For the FWHM, the value was 2.25° at 0.01 until 0.08 ppm and decreases to 2.12° at 0.1 until 10 ppm. The DA for the SPR curves is the highest at 0.01 until 0.08 ppm and lowest at 0.1 until 10 ppm. The SNR curves mirrors the curves of SPR angle shift where the SNR increases with the Ni 2+ concentrations. For the selectivity test, the CTA-NCC/GO has the abilities to differentiate Ni 2+ in the mixture of metal ions., (Copyright © 2018 Elsevier B.V. All rights reserved.)

In this research, surface plasmon resonance (SPR) spectroscopy was used for sensing copper ion by combining the SPR with nanocrystalline cellulose modified by hexadecyltrimethylammonium bromide and graphene oxide composite (CTA-NCC/GO) thin film. The binding of Cu 2+ on CTA-NCC/GO thin film was monitored by using SPR spectroscopy. By using the obtained SPR curve, detection range, binding affinity, sensitivity, full width at half maximum (FWHM), data accuracy (DA), and signal-to-noise ratio (SNR) have been calculated. The results showed that the sensor detection range was 0.01 until 0.5 ppm, and that it reached a saturation value. Moreover, the resonance angle shift followed the Langmuir isotherm model with a binding affinity constant of 4.075 × 10 3 M -1 . A high sensitivity of 3.271° ppm -1 also was obtained for low Cu 2+ concentration ranged from 0.01 to 0.1 ppm. For the FWHM, the lowest value calculated was at 0.08 and 0.1 ppm, which is 3.35°. The DA of the SPR signal consecutively highest at 0.08 and 0.1 ppm. Besides that, the SNR of the SPR signal increases with the Cu 2+ concentrations. The CTA-NCC/GO thin film morphological properties were also studied by using atomic force microscopy. The rms roughness values, which were obtained before and after in contact with Cu 2+, were 3.51 nm and 2.46 nm, respectively.

Biosorption, a non-expensive and easy method for removing potentially toxic metal ions from water, has been the subject of extensive research. In this context, this study introduces a novel approach using sodium alginate and chitosan, versatile biopolymers that have shown excellent results as biosorbents. The challenge of maintaining high efficiencies and reuse is addressed by developing alginate/chitosan-based films. These films, prepared using solvent casting and crosslinking methods, form a hydrogel network. The alginate/chitosan-based films, obtained using the eco-friendly polyelectrolyte complex method, were characterized by FTIR, SEM, TGA, and DSC. The study of their swelling pH response, adsorption, and desorption behavior revealed promising results. The adsorption of Pb was significantly enhanced by the presence of both biopolymers (98%) in a shorter time (15 min) at pH = 6.5. The adsorption of both ions followed a pseudo-second-order kinetic and the Langmuir isotherm model. The desorption efficiencies for Cd and Pb were 98.8% and 77.6% after five adsorption/desorption cycles, respectively. In conclusion, the alginate/chitosan-based films present a highly effective and novel approach for removing Cd and Pb from water, with a promising potential for reuse, demonstrating their strong potential in potentially toxic metal removal. [ABSTRACT FROM AUTHOR]

In the present work, graphene oxide (GO)–polyvinyl alcohol (PVA) composites thin film has been successfully synthesized and prepared by spin coating techniques. Then, the properties and morphology of the samples were characterized using Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV-Vis), and atomic force microscopy (AFM). Experimental FTIR results for GO–PVA thin film demonstrated the existence of important functional groups such as -CH2 stretching, C=O stretching, and O–H stretching. Furthermore, UV-Vis analysis indicated that the GO–PVA thin film had the highest absorbance that can be observed at wavelengths ranging from 200 to 500 nm with a band gap of 4.082 eV. The surface morphology of the GO–PVA thin film indicated the thickness increased when in contact with carbaryl. The incorporation of the GO–PVA thin film with an optical method based on the surface plasmon resonance (SPR) phenomenon demonstrated a positive response for the detection of carbaryl pesticide as low as 0.02 ppb. This study has successfully proposed that the GO–PVA thin film has high potential as a polymer nanomaterial-based SPR sensor for pesticide detection. [ABSTRACT FROM AUTHOR]

Food safety is the basis for ensuring human survival and development. The threat of heavy metal ions to food safety has become a social concern with the rapid growth of the economy and the accompanying environmental pollution. Some heavy metal ions are highly toxic even at trace levels and pose significant health risks to humans. Therefore, ultrasensitive detection of heavy metal ions in food samples is important. In this mini-review, recent advances in the analytical methods based on nanomaterials for detecting trace heavy metal ions in food samples are summarized in three categories: electrochemical, colorimetric, and fluorescent methods. We present the features and sensing mechanisms of these three methods, along with typical examples to illustrate their application in the detection of heavy metal ions in foods. This mini-review ends with a discussion of current challenges and future prospects of these approaches for sensing heavy metal ions. The review will help readers understand the principles of these methods, thereby promoting the development of new analytical methods for the detection of heavy metal ions in food samples. [ABSTRACT FROM AUTHOR]

This research study focuses on the investigation of a three-dimensional reconstructed carbon coating based on stainless steel. The investigation encompasses the assessment of surface structure, elemental composition, cytotoxicity, and impact on wound healing. The findings indicate that the carbon coating possesses an approximate thickness of 700 nm, exhibiting a distinctive porous structure. Moreover, the surface water contact angle measures 97.7°, representing a 48.4° increase compared to uncoated stainless steel. Energydispersive spectroscopy (EDS) analysis confirms the uniform distribution of diverse elements on the coating's surface. Additionally, X-ray photoelectron spectroscopy (XPS) verifies a substantial carbon accumulation. The electrical resistance of the stainless steel remains largely intact after the application of the coating, as demonstrated by the four-probe method. Notably, ex vivo porcine liver tissue cutting experiments using carbon-coated electrosurgical pencil electrodes showed a significant anti-adhesion effect, with a reduction in tissue adhesions of 81.3%. Furthermore, the MTT test indicates no significant cytotoxicity associated with the carbon coating. Rat skin-cutting experiments further validate that the coating does not impede the process of wound healing. Overall, this study successfully validated the desirable properties of stainless steel-based 3D reconstructed carbon coatings, such as enhanced surface properties, improved anti-adhesion efficacy, negligible cytotoxicity, and compatibility with wound healing. These findings are important for advancing medical device technology and improving patient outcomes. [ABSTRACT FROM AUTHOR]

Mosquito-borne diseases pose significant public health threats worldwide, necessitating effective prevention strategies. Traditional chemical agents used for mosquito bite prevention often carry environmental and health risks. In this review, we explore the potential of graphene-based films as a non-chemical approach for protecting against mosquito bites. The aim of this review is to assess the effectiveness of multilayer graphene films in preventing mosquito bites and to explore their practical implications for public health. Through experimental investigations, researchers found that dry multilayer graphene films effectively block mosquitoes' ability to detect skin or sweat chemicals, thereby preventing mosquito bites. Additionally, these films can serve as physical barriers to the mosquito's feeding mechanism. The findings suggest promising applications of graphene films in protective technologies for human skin and smart fabrics. Graphene's non-toxic nature and ease of application make it an attractive alternative to chemical repellents. Implementing graphene-based films for mosquito bite prevention could potentially reduce the transmission of mosquito-borne diseases, addressing critical public health concerns. In conclusion, this review highlights the potential of graphene films as a non-chemical method for mosquito bite prevention. Future research should focus on evaluating the long-term effectiveness and safety of graphene films, paving the way for the development of innovative technologies that utilize graphene to safeguard against mosquito bites and mitigate the spread of infectious diseases. [ABSTRACT FROM AUTHOR]

CuInGaSe2 crystals were synthesized using the traditional melt method. Various thicknesses of thin films were formed on glass substrates at room temperature using the thermal evaporation method. In the wavelength range of 250–2500 nm, the optical absorption spectra of thin films were examined. To calculate the optical band gap of the films, Taucs’ relation was applied. Calculations were made to determine how the film thickness affected the energy gap of CuInGaSe2 thin films. Estimation have been made to show fluctuations in the direct optical band gap values with variations in film thickness, but the indirect band gap energy varies systematically with thickness. [ABSTRACT FROM AUTHOR]

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein (NP) participates in viral genome packaging and abundantly produced when infected. In this work, SPR biosensor for the detection of SARS-CoV-2 in viral fluid using Fv-antibodies with the binding affinity to nucleocapsid protein (NP) of SARS-CoV-2. The FV-antibodies with a specific binding activity to the SARS-CoV-2 NP were screened using the FV-antibody library, which was expressed on the outer membrane of E. coli. FV-antibodies comprised three complementarity-determining regions (CDRs) and four frame regions (FRs) of the heavy chain at the binding pocket of IgG. The FV-antibody library was prepared by performing site-directed mutagenesis and by using the autodisplay technology; FV-antibodies with specific binding activities to the nucleocapsid protein (NP) of SARS-CoV-2 were screened using NP-immobilized magnetic beads. First, E. coli isolates with the target FV-antibody were screened, and the binding affinity (KD) was estimated for the screened E. coli clones using FACS analysis. Then, the outer membrane (OM) of the screened E. coli clones with autodisplayed Fv-antibodies was obtained and layered on an SPR biosensor, and the binding curves of four different coronavirus (CoV) culture fluids, SARS-CoV-2, SARS-CoV, MERS-CoV, and CoV strain 229E, were compared. Finally, the FV-antibodies of the screened E. coli clones were synthesized as peptides (11 amino acid residues), and the binding constants (KD) to NP as well as the binding curves of the CoV strains in culture fluids were estimated. Using docking simulation, binding sites and interaction types between NP and each synthetic peptide were investigated. [ABSTRACT FROM AUTHOR]

Central venous catheters (CVCs) are largely used to administer chemotherapy, hemodialysis, and other treatments. Mostly made of polydimethylsiloxane (PDMS), these medical devices present an intrinsic risk of infection due to the possible formation of biofilm, thus increasing the risk of complications. Drug-releasing polymer coatings are a well-recognized strategy for combating biofilm formation. However, adhesion of the coating to the substrate over time is a major challenge. Therefore, this work aimed to design a chitosan-based coating designed to have maximum adhesion and stability to guarantee sustained drug release and antibacterial properties for at least 14 days. A coating composed of chitosan (CS) as a drug carrier, caffeic acid (CA) and copper sulphate (Cu) as crosslinkers, and moxifloxacin (Mox) as an antibiotic, was deposited through a controlled casting process onto functionalized PDMS surface. PDMS surface modification was investigated by X-ray photoelectron spectroscopy (XPS), and Fourier-transfer infrared (FTIR). Antibiotic release over time was measured in pseudo-physiological conditions (pH 7.4 and at 37 °C). Indirect cytotoxicity assays were performed on human dermal fibroblasts (HDF). The adhesion of the as-designed coating was evaluated by a specially designed pull-off test, before and after aging for 14 days in PBS. XPS and FTIR analyses confirmed the successful PDMS surface modification. The CS-CA-Cu-Mox coating resulted in being non-cytotoxic towards HDF and exhibited sustained moxifloxacin release for up to 49 days. Furthermore, the CS-CA and CS-CA-Cu coatings presented antibacterial activity for 21 days against E. coli, and for 14 days against S. aureus. Importantly, the coating maintained stable adhesion after 14 days in pseudo-physiological conditions. This study provides new insights into the adhesion behavior of polymeric coatings for medical devices, which is rarely reported in the literature. [ABSTRACT FROM AUTHOR]

Quantum dots (QDs) have captured the attention of the scientific community due to their unique optical and electronic properties, leading to extensive research for different applications. They have also been employed as sensors for ionic species owing to their sensing properties. Detecting anionic species in an aqueous medium is a challenge because the polar nature of water weakens the interactions between sensors and ions. The anions bicarbonate (HCO3−), carbonate (CO32−), sulfate (SO42−), and bisulfate (HSO4−) play a crucial role in various physiological, environmental, and industrial processes, influencing the regulation of biological fluids, ocean acidification, and corrosion processes. Therefore, it is necessary to develop approaches capable of detecting these anions with high sensitivity. This study utilized CdTe QDs stabilized with cysteamine (CdTe-CYA) as a fluorescent sensor for these anions. The QDs exhibited favorable optical properties and high photostability. The results revealed a gradual increase in the QDs' emission intensity with successive anion additions, indicating the sensitivity of CdTe-CYA to the anions. The sensor also exhibited selectivity toward the target ions, with good limits of detection (LODs) and quantification (LOQs). Thus, CdTe-CYA QDs show potential as fluorescent sensors for monitoring the target anions in water sources. [ABSTRACT FROM AUTHOR]

A novel vanadium–cellulose composite thin film-based on angular interrogation surface plasmon resonance (SPR) sensor for ppb-level detection of Ni(II) ion was developed. Experimental results show that the sensor has a linear response to the Ni(II) ion concentrations in the range of 2–50 ppb with a determination coefficient (R2) of 0.9910. This SPR sensor can attain a maximum sensitivity (0.068° ppb−1), binding affinity constant (1.819 × 106 M−1), detection accuracy (0.3034 degree−1), and signal-to-noise-ratio (0.0276) for Ni(II) ion detection. The optical properties of thin-film targeting Ni(II) ions in different concentrations were obtained by fitting the SPR reflectance curves using the WinSpall program. All in all, the proposed Au/MPA/V–CNCs–CTA thin-film-based surface plasmon resonance sensor exhibits better sensing performance than the previous film-based sensor and demonstrates a wide and promising technology candidate for environmental monitoring applications in the future. [ABSTRACT FROM AUTHOR]

A high photoluminescence (PL)-based nanosensor based on graphene quantum dots (GQDs) is fabricated for the detection of toxic ions Ag+, Ce2+, Cd2+, Cu2+, Cr2+, Pb2+, Sn2+, and Fe3+, p-nitrophenol, and thioacetamide in water. The quenching of PL spectra indicates that the complex of GQDs/Fe(III) shows a high florescent quenching efficiency (~ 75%) toward the hydrophobic surface of the GQDs. The limit of detection for Fe(III) concentration 40 ± 2 nM, with high linearity and sensitivity. The change of the zeta potential value proves the attachment of Fe (III) ions to the surface of the GQDs. The GQDs/Fe(III) complexes can be utilized as a turn-OFF or turn-ON type fluorescence probe for p-nitrophenol (turn-OFF) detection with 5 ± 1 pM concentration and the sulfur (turn-ON) detection with 7.6 ± 1 pM. The proposed method is facile, sensitive and fast, which makes it ideal for nanosensors to detect water quality of rivers, ponds, or industrial wastes. [ABSTRACT FROM AUTHOR]

The amplification of the surface plasmon resonance (SPR) sensitivity for the foot-and-mouth disease (FMD) detection was studied using Poly(amidoamine) (PAMAM) succinamic-acid dendrimers. The dendrimers were conjugated with the complementary annealed with the aptamers capable of binding specifically to FMD peptides. The tethered layer of the dendrimer-conjugated double-stranded(ds)-aptamers was formed on the SPR sensor Au surface via a thiol bond between the aptamers and Au. After the tethered layer was formed, the surface was taken out of the SPR equipment. Then, the ds-aptamers on the surface were denatured to collect the dendrimer-conjugated single-stranded(ss)-complementary. The surface with only the remaining ss-aptamers was transferred again to the equipment. Two types of the injections, the FMD peptide only and the dendrimer-conjugated ss-complementary followed by the FMD peptides, were performed on the surface. The sensitivity was increased 20 times with the conjugation of the dendrimers, but the binding rate of the peptides became more than two times slower. [ABSTRACT FROM AUTHOR]

This review paper provides an in-depth analysis of recent advancements in integrating two-dimensional (2D) materials with cellulose to enhance biosensing technology. The incorporation of 2D materials such as graphene and transition metal dichalcogenides, along with nanocellulose, improves the sensitivity, stability, and flexibility of biosensors. Practical applications of these advanced biosensors are explored in fields like medical diagnostics and environmental monitoring. This innovative approach is driving research opportunities and expanding the possibilities for diverse applications in this rapidly evolving field. [ABSTRACT FROM AUTHOR]

Aptamers, short strands of either DNA, RNA, or peptides, known for their exceptional specificity and high binding affinity to target molecules, are providing significant advancements in the field of health. When seamlessly integrated into biosensor platforms, aptamers give rise to aptasensors, unlocking a new dimension in point-of-care diagnostics with rapid response times and remarkable versatility. As such, this review aims to present an overview of the distinct advantages conferred by aptamers over traditional antibodies as the molecular recognition element in biosensors. Additionally, it delves into the realm of specific aptamers made for the detection of biomarkers associated with infectious diseases, cancer, cardiovascular diseases, and metabolomic and neurological disorders. The review further elucidates the varying binding assays and transducer techniques that support the development of aptasensors. Ultimately, this review discusses the current state of point-of-care diagnostics facilitated by aptasensors and underscores the immense potential of these technologies in advancing the landscape of healthcare delivery. [ABSTRACT FROM AUTHOR]

High-sensitivity gold-coated photonic crystal fiber (PCF) refractive index (RI) biosensor based on surface plasmon resonance (SPR) is proposed. To evaluate the sensing characteristics of the proposed sensor, the finite element method (FEM) is used. As a base material, silica is used and as a plasmonic material, 40-nm thickness gold layer is chosen. Resonance of electrons requires active plasmonic material. Gold is chosen because it has the highest plasmonic activity of all active plasmonic materials and offers the best resonance. The uppermost wavelength sensitivity response of 45,409.14 nm/RIU is obtained at RI 1.35. The maximum amplitude resolution, amplitude sensitivity response, birefringence, transmittance, coupling length, and dispersion of 2.52 × 10−05, 7679.06 RIU−1, 3.1 × 10−4, − 24.5 dB, 1,87,500 µm, and − 7000 ps/(nm-km) are obtained respectively. The proposed sensor is a strong contender for detecting microfluidic analytes in the biosensor field for its exceptional sensitivity response, compact structural design, and tunable performance. [ABSTRACT FROM AUTHOR]

This work aims to develop a surface plasmon resonance (SPR) sensor based on Chitosan/Polyaniline/Graphene oxide-Ferrocene (CS/PANI/GOFc) composite thin film for glucose detection. The optimum formulation of the composite has been calculated from experimental refractive index data and using the effective medium theory (EMT). Then, the optimum composite, CS 25%/PANI 25%/GOFc 50%, has been prepared and evaluated in the design of the glucose sensor via modification of the SPR gold chip. Results demonstrate that the linear response of the SPR sensor is in the range of 0.5–100 µM of glucose with a sensitivity of 0.0202° μM−1. The Langmuir and Sips models have been used to analyze the binding affinity, which represents a higher affinity constant for the composite film compared to the bare gold chip. [ABSTRACT FROM AUTHOR]

A novel Chitosan/Indium sulfide (CS/In2S3) nanocomposite was created by co-precipitating Chitosan and InCl3 in solution, resulting in In2S3 agglomeration on the Chitosan matrix with a remarkable pore diameter of 170.384 Å, and characterized it for the physical and chemical properties. Under optimal conditions (pH = 7, time = 60 min, catalyst dosage = 0.24 g L−1, and dye concentration = 100 mg L-1), the synthesized nanocomposite demonstrated remarkable adsorption capabilities for Victoria Blue (VB), attaining a removal efficiency of 90.81%. The Sips adsorption isotherm best matched the adsorption process, which followed pseudo-second-order kinetics. With a rate constant of 6.357 × 10–3 g mg−1 min−1, the highest adsorption capacity (qm) was found to be 683.34 mg g−1. Statistical physics modeling (SPM) of the adsorption process revealed multi-interaction and multi-molecular adsorption of VB on the CS/In2S3 surface. The nanocomposite demonstrated improved stability and recyclability, indicating the possibility for low-cost, reusable wastewater dye removal adsorbents. These results have the potential to have practical applications in environmental remediation. [ABSTRACT FROM AUTHOR]

This work presents the results of research on obtaining chitosan (CS) films containing on their surface ciprofloxacin (CIP). A unique structure was obtained that not only gives new properties to the films, but also changes the way of coverage and structure of the surface. The spectroscopic test showed that in the process of application of CIP on the surface of CS film, CIP was converted from its crystalline form to an amorphic one, hence improving its bioavailability. This improved its scope of microbiological effect. The research was carried out on the reduction of CIP concentration during the process of CIP adhesion to the surface of chitosan films. The antibacterial activity of the CS films with and without the drug was evaluated in relation to Escherichia coli and Staphylococcus aureus, as well as Candida albicans and Penicillium expansum. Changes in the morphology and roughness of membrane surfaces after the antibacterial molecule adhesion process were tested with atomic force microscopy (AFM) and scanning electron microscopy (SEM). Structural analysis of CS and its modifications were confirmed with Fourier-transform spectroscopy in the infrared by an attenuated total reflectance of IR radiation (FTIR-ATR) and solid-state nuclear magnetic resonance (NMR). [ABSTRACT FROM AUTHOR]

Water pollution on account of textile industrial effluents represents a serious environmental problem which is increasing day by day. This study reports the synthesis of metal sulfide/chitosan nanocomposites (MS/chit NCs), M=Ni, Cd, via three steps: (1) synthesis of M(Tu) complex, Tu=thiourea, by a simple reflux route, employing metal nitrates and thiourea as the reactants (2) synthesis of MS nanostructures by simple thermal decomposition method using [M(Tu)] as precursors (3) synthesis of MS/chitosan nanocomposites. The fabricated nanostructures and nanocomposites were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). The adsorption is one of the most efficient techniques for removing the pollution from the solvent phase. The nanocomposites synthesized in this work could help to solve the waste disposal problem. They were applied for the MB removal from aqueous solution. The intensity of peaks of MB were decreased after their adsorption on the surface of the nanocomposites in UV-Vis spectra. [ABSTRACT FROM AUTHOR]

The purpose of this research work was to synthesis bioderived nanocomposite films by incorporating Na0.5Bi0.5TiO3 (NBTO) nanoparticles into a chitosan matrix. The NBTO nanoparticles were synthesized using a traditional solid-state technique. Then, through a solution-casting approach, flexible composite films were fabricated using chitosan polymer. The study presents a range of compelling findings. For structural and morphological insights, scanning electron microscopy (SEM) reveals a fascinating morphology where NBTO nanoparticles are uniformly dispersed and interlocked with other particles, forming interconnected grains with significant interspaces within the chitosan matrix. For the optical properties, the spectral response within the 300–800 nm range is primarily governed by light scattering attributed to NBTO particles with diameter sizes ranging from 100 to 400 nm, as well as the distinctive bandgap exhibited by the NBTO phase. The investigation of dielectric properties demonstrates that composite films exhibit markedly higher dielectric values in comparison to pure chitosan films. It is noteworthy that an increase in the NBTO content results in a corresponding increase in dielectric values, enhancing the versatility of these materials. Local piezoelectric measurements utilizing piezoresponse force microscopy confirm the expected piezoelectric and ferroelectric behavior of NBTO particles when dispersed within the chitosan matrix. This research introduces a novel class of biocompatible nanocomposite materials, combining impressive structural attributes, enhanced dielectric properties, and piezoelectric capabilities. The outcomes of this study hold substantial promise for advanced applications in opto- and piezoelectric technologies, marking a significant advancement in biologically sourced materials with multifunctional properties. [ABSTRACT FROM AUTHOR]

The angular interrogation of hybrid modes of sensitivity of surface plasmon polariton waves (SPPs) at the interface of chiral atomic medium and silver metal by using grating geometry is investigated in this manuscript. The cross coupling of electric and magnetic fields in chiral medium generates hybrid modes of sensitivity S ± of SPPs. The hybrid modes of sensitivity strongly depend upon the diffraction order, grating period and driving fields parameters. The hybrid modes of sensitivity ( S ± ) are the functions of control field Rabi frequency, decay rate and probe detuning. The maximum value of S (+) is investigated to 1500 deg/RIU and S (-) is reported to 800 deg/RIU. The hybrid modes of sensitivity show significant applications in nano-photonics and plasmonster based sensing technology. [ABSTRACT FROM AUTHOR]

A novel design of a surface plasmon resonance (SPR) sensor based on the heterostructure of 2D nanomaterials, viz. blue phosphorus (BlueP) and molybdenum disulfide (MoS2), coupled with an adhesive layer of zinc oxide (ZnO) is presented here to enable significant plasmonic performance enhancement. The five-layer SPR system based on the Kretschmann configuration consists of ZnO sandwiched between a BK7 glass prism and gold (Au) layer, a BlueP-MoS2 heterostructure, and a sensing medium. The numerical analysis of the proposed sensor is carried out using the transfer matrix method and the sensor performance parameters; sensitivity, full width at half maximum (FWHM), and quality factor (QF) are studied at an operating wavelength of 633 nm for refractive index change in the range 1.33–1.335 RIU. The thicknesses of the Au, ZnO, and BlueP-MoS2 heterostructure layers are optimized and the sensitivity (260°/RIU) and QF (48.14 RIU−1) of the proposed sensor with 48 nm Au, 6 nm ZnO, and a monolayer of BlueP-MoS2 (0.75 nm) are enhanced by 51.16% and 19.3% over the conventional SPR sensor. The rational design of the proposed SPR sensor delivering significantly large sensitivity is suited for experimental realization to deploy ZnO as an effective adhesive layer with the BlueP-MoS2 heterostructure for improved sensing performance. [ABSTRACT FROM AUTHOR]

This study aims to develop a refractive-index sensor operating in the visible region using an all-dielectric metasurface, which was chosen for its advantages of low optical loss and narrow spectral bandwidth, compared to those of conventional metallic metasurfaces. COMSOL software was utilized as a calculation tool to simulate the resonant properties of an all-dielectric metasurface composed of a circular nanohole-structured titanium oxide (TiO2) thin film, with the aim of enhancing the sensitivity of the refractive index for sensing targets. The simulation focused on finding the best geometrical conditions for the all-dielectric metasurface to achieve high sensitivity. Two resonance modes observed in this metasurface were considered: the quasi-bound-state-in-the-continuum (qBIC) mode and the perfect-reflection (PR) mode. The simulated results demonstrated that high sensitivities of 257 nm/RIU at the PR mode and 94 nm/RIU at the qBIC mode in the visible spectral range could be obtained by periodically constructing the metasurface with a unit cell having a lattice constant of 350 nm, a nanohole radius of 160 nm, and a nanohole depth of 250 nm. Furthermore, the study showed that the resonance mode that enabled high sensitivity was the PR mode, with a sensitivity nearly three times larger than that of the qBIC mode and the ability to reach the highest reflectance at the resonance wavelength. The optimized feature had the highest reflectance at a resonant wavelength of 570.19 nm, and although the quality factor was 25.50, these designed parameters were considered sufficient for developing a refractive index biosensor with high sensitivity and optical efficiency when operating in the visible spectral range. [ABSTRACT FROM AUTHOR]

A naphthalene diimide dye with two side amine arm was prepared. Uv–Vis and fluorescence spectroscopic techniques are used for their photophysical and solvatochromic characteristics in different solvents. The Lippert-Mataga plot for naphthalene diimide demonstrated a negative linear dependence by increasing polarity. Results showed naphthalene diimide is more polar in the ground than in the excited state. A quenching study was conducted for interacting the naphthalene diimide as a fluorophore and graphene oxide as a quencher. Fluorescence quenching-based platforms in nanoscale have been used in sensing systems. Raman, FTIR, Uv–Vis and fluorescence spectroscopic techniques were used to study the quenching mechanism. The results indicated that graphene plays an effective quencher against the naphthalene diimide, with a quenching efficiency 91%. The Stern–Volmer analysis results show a mix of static and dynamic quenching mechanisms. The binding constant of the quencher-fluorophore and the number of binding sites have been reported. Thermodynamic parameters of their interaction were evaluated. The negative values of the Gibbs free energy confirm that the complexation process is spontaneous. Meanwhile, the positive entropy value confirms that the favorable pathway process. [ABSTRACT FROM AUTHOR]

Water contamination by mercury ions (Hg 2+ ) causes irreversible and serious effect on the ambient environment, ecological systems, and human health, necessitating further improvement of Hg 2+ monitoring at low concentrations. Here, we proposed a novel surface plasmon resonance (SPR) sensor for Hg 2+ detection with desirable advantages of high sensitivity, simple operation, label-free, and low cost, in which the chitosan/poly (vinyl alcohol)/SnO 2 composite film was modified on sensing surface as the active layer for sensitivity enhancement. Benefiting from the relatively high refractive index of SnO 2 nanoparticles, the evanescent field generated at the metal-solution interface can be significantly enhanced, which results in a 5 times improvement of sensitivity. Through appropriate optimization in the aspects of componential constitutions, the sensor exhibits excellent sensitivity of 25.713 nm/μg/L and ultra-low calculated detection limit of 6.61 ng/L(32.95 pM). Such detection limit is strikingly lower than the limitation (10 nM) in drinking water set by the US Environmental Protection Agency. In addition, the as-prepared sensor presents relatively high selectivity for Hg 2+ , attributing to plenty of binding sites for specific adsorption produced by functionalized chitosan/poly (vinyl alcohol) composites, which have been furtherly verified by characterization of FTIR and XPS spectra. The proposed sensor also exhibits great repeatability and good time stability for 15 days. This work provides a promising strategy for developing high-performance SPR sensor for Hg 2+ detection and a prospective application in environmental monitoring., (© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.)

Metal ions are used in various situations in living organisms and as a part of functional materials. Since the excessive intake of metal ions can cause health hazards and environmental pollution, the development of new molecules that can monitor metal ion concentrations with high sensitivity and selectivity is strongly desired. DNA can form various structures, and these structures and their properties have been used in a wide range of fields, including materials, sensors, and drugs. Guanine-rich sequences respond to metal ions and form G-quadruplex structures and G-wires, which are the self-assembling macromolecules of G-quadruplex structures. Therefore, guanine-rich DNA can be applied to a metal ion-detection sensor and functional materials. In this study, the IRDAptamer library originally designed based on G-quadruplex structures was used to screen for Mn2+, which is known to induce neurodegenerative diseases. Circular dichroism and fluorescence analysis using Thioflavin T showed that the identified IRDAptamer sequence designated MnG4C1 forms a non-canonical G-quadruplex structure in response to low concentrations of Mn2+. A serum resistance and thermostability analysis revealed that MnG4C1 acquired stability in a Mn2+-dependent manner. A Förster resonance energy transfer (FRET) system using fluorescent molecules attached to the termini of MnG4C1 showed that FRET was effectively induced based on Mn2+-dependent conformational changes, and the limit of detection (LOD) was 0.76 µM for Mn2+. These results suggested that MnG4C1 can be used as a novel DNA-based Mn2+-detecting molecule. [ABSTRACT FROM AUTHOR]

Surface plasmon resonance (SPR)--based biosensors compete and excel among optical biosensors because of exceptional features such as high sensitivity, label-free, and real-time measurement, allowing the observation of molecular binding kinetics. In SPR biosensors and other biosensor techniques, surface functionalization and bioreceptor attachment are effective strategies to improve sensor performance. The application of an appropriate immobilization matrix for the bioreceptor is an essential step in maximizing the absorption of the bioreceptor on the sensor surface, thereby improving a specific target-sensor interaction. Furthermore, the materials should provide excellent optical properties to enhance the response signal. The high surface-to-volume ratio and high optical absorption of 2D materials qualify these requirements, thus promising advancements for SPR biosensors. This article reviews the recent SPR biosensor study with the use of the 2D materials family to improve the sensor performance, including graphene, transition metal dichalcogenides (TMDCs), MXene, black phosphorus (BP), perovskite, and boron nitride (BN). The materials properties and enhancement mechanisms of different 2D materials are discussed comprehensively. This review was expected to provide a future perspective and design approach for 2D materials-based SPR biosensors. [ABSTRACT FROM AUTHOR]

This paper proposes a novel optical fiber sensor for highly sensitive Hg2+ detection based on Mach–Zehnder interference (MZI) structure and thiophene–chitosan hydrogel (TCH). We obtained the MZI structure by splicing the coreless fiber (CLF), thin core fiber, and CLF. And then, we etched the thin-core optical fiber cladding and assembled the TCH to produce a Hg2+ sensitive sensor. According to theoretical derivation and experimental verification, the detection sensitivity of the sensor to Hg2+ can reach 1.008 × 1011 mol l−1, and the detection limit is 5 × 10−13 mol l−1. The sensor also has performance stability within 24 h for concentration measurement, with an average standard deviation of 3.2 × 10−13 mol l−1 within an hour of observation. In addition, the sensor has the advantages of specificity, simple preparation, and low cost, and it is suitable for monitoring the concentration of Hg2+ in complex water systems. [ABSTRACT FROM AUTHOR]

In this work, cellulose-based nanocomposite films having trimetallic (Bi, Fe, and Sn) nanoparticles were prepared by green adaptive methodology using Terminalia arjuna leaf extract as a reducing and stabilizing agent. Then, they were characterized by FTIR and SEM. The color change of microcrystalline cellulose films revealed the formation of the trimetallic (Bi, Fe, Sn) nanoparticles. Characteristics absorption peaks for reducing functional groups indicated the presence and role of the plant material used; moreover, the presence of various bands in FTIR spectra below 1000 cm−1 was indicative of the formation of (Bi, Fe, and Sn) nanocomposites. These synthesized nanomaterials were also tested for their antimicrobial potency against Escherichia coli and Pseudomonas aeruginosa. Positive outcomes designated their potential to be adopted for biomedical applications and in food packaging as an alternative of synthetic plastics to control pollution. [ABSTRACT FROM AUTHOR]

Chitosan is a fibrous compound derived from chitin, which is the second most abundant natural polysaccharide and is produced by crustaceans, including crabs, shrimps, and lobsters. Chitosan has all of the important medicinal properties, including biocompatibility, biodegradability, and hydrophilicity, and it is relatively nontoxic and cationic in nature. Chitosan nanoparticles are particularly useful due to their small size, providing a large surface-to-volume ratio, and physicochemical properties that may differ from that of their bulk counterparts; thus, chitosan nanoparticles (CNPs) are widely used in biomedical applications and, particularly, as contrast agents for medical imaging and as vehicles for drug and gene delivery into tumors. Because CNPs are formed from a natural biopolymer, they can readily be functionalized with drugs, RNA, DNA, and other molecules to target a desired result in vivo. Furthermore, chitosan is approved by the United States Food and Drug Administration as being Generally Recognized as Safe (GRAS). This paper reviews the structural characteristics and various synthesis methods used to produce chitosan nanoparticles and nanostructures, such as ionic gelation, microemulsion, polyelectrolyte complexing, emulsification solvent diffusion, and the reverse micellar method. Various characterization techniques and analyses are also discussed. In addition, we review drug delivery applications of chitosan nanoparticles, including for ocular, oral, pulmonary, nasal, and vaginal methodologies, and applications in cancer therapy and tissue engineering. [ABSTRACT FROM AUTHOR]

Heavy metal ions, one of the major pollutants in the environment, exhibit non-degradable and bio-chain accumulation characteristics, seriously damage the environment, and threaten human health. Traditional heavy metal ion detection methods often require complex and expensive instruments, professional operation, tedious sample preparation, high requirements for laboratory conditions, and operator professionalism, and they cannot be widely used in the field for real-time and rapid detection. Therefore, developing portable, highly sensitive, selective, and economical sensors is necessary for the detection of toxic metal ions in the field. This paper presents portable sensing based on optical and electrochemical methods for the in situ detection of trace heavy metal ions. Progress in research on portable sensor devices based on fluorescence, colorimetric, portable surface Raman enhancement, plasmon resonance, and various electrical parameter analysis principles is highlighted, and the characteristics of the detection limits, linear detection ranges, and stability of the various sensing methods are analyzed. Accordingly, this review provides a reference for the design of portable heavy metal ion sensing. [ABSTRACT FROM AUTHOR]

Phenols are widely used in industries despite their toxicity, which requires governments to limit their concentration in water to 5 mg/L before discharge to the city sewer. Thus, it is essential to develop a rapid, simple, and low-cost detection method for phenol. This study explored two pathways of peroxidase immobilization to develop a phenol detection system: peroxidase encapsulation into polyelectrolyte microcapsules and peroxidase captured by CaCO3. The encapsulation of peroxidase decreased enzyme activity by 96%; thus, this method cannot be used for detection systems. The capturing process of peroxidase by CaCO3 microspherulites did not affect the maximum reaction rate and the Michaelis constant of peroxidase. The native peroxidase—Vmax = 109 µM/min, Km = 994 µM; CaCO3–peroxidase—Vmax = 93.5 µM/min, Km = 956 µM. Ultimately, a reusable phenol detection system based on CaCO3 microparticles with immobilized peroxidase was developed, capable of detecting phenol in the range of 700 ng/mL to 14 µg/mL, with an error not exceeding 5%, and having a relatively low cost and production time. The efficiency of the system was confirmed by determining the content of phenol in a paintwork product. [ABSTRACT FROM AUTHOR]

In recent years, there has been an increased demand for highly sensitive and selective biosensors for neurotransmitters, owing to advancements in science and technology. Real-time sensing is crucial for effective prevention of neurological and cardiovascular diseases. In this review, we summarise the latest progress in aptamer-based biosensor technology, which offers the aforementioned advantages. Our focus is on various biomaterials utilised to ensure the optimal performance and high selectivity of aptamer-based biosensors. Overall, this review aims to further aptamer-based biosensor technology. [ABSTRACT FROM AUTHOR]

A novel and efficient colorimetric assay was developed for the detection of copper ions (Cu2+) in real environmental water based on analyte-mediated peroxidase-mimicking activity enhancement of cysteine-capped silver nanoparticles (RSH-AgNPs). These RSH-AgNPs show a synergetic effect in the form of peroxidase-mimicking activity enhancement by analyte mediation, and free RSH-AgNPs alone have weak catalytic properties. While coexisting with Cu2+, RSH-AgNPs possess excellent enzymatic activity due to the dissociation of cysteine on the interface of silver nanoparticles caused by Cu2+ and exposing the catalytic sites of AgNPs, which can catalyze the decomposition of hydrogen peroxide and trigger the oxidation of 3,3',5,5'-tetramethylbenzidine, leading to a change in color from colorless to blue. Using this strategy, Cu2+ could be determined within a wide linear range of concentrations (0.1 to 83 μM) with the detection limit of 0.08 μM using colorimetric detection. This method has excellent anti-interference capability and is effective and reliable for the determination of Cu2+ in real water samples. [ABSTRACT FROM AUTHOR]

Every year, the dengue virus and its principal mosquito vector, Aedes sp., have caused massive outbreaks, primarily in equatorial countries. The pre-existing techniques available for dengue detection are expensive and require trained personnel. Graphene and its derivatives have remarkable properties of electrical and thermal conductivity, and are flexible, light, and biocompatible, making them ideal platforms for biosensor development. The incorporation of these materials, along with appropriate nanomaterials, improves the quality of detection methods. Graphene can help overcome the difficulties associated with conventional techniques. In this review, we have given comprehensive details on current graphene-based diagnostics for dengue virus detection. We have also discussed state-of-the-art biosensing technologies and evaluated the advantages and disadvantages of the same. [ABSTRACT FROM AUTHOR]

Increases in community and industrial activities have led to disturbances of the environmental balance and the contamination of water systems through the introduction of organic and inorganic pollutants. Among the various inorganic pollutants, Pb (II) is one of the heavy metals possessing non-biodegradable and the most toxic characteristics towards human health and the environment. The present study is focussed on the synthesis of efficient and eco-friendly adsorbent material that can remove Pb (II) from wastewater. A green functional nanocomposite material based on the immobilization of α-Fe2O3 nanoparticles with xanthan gum (XG) biopolymer has been synthesized in this study to be applied as an adsorbent (XGFO) for sequestration of Pb (II). Spectroscopic techniques such as scanning electron microscopy with energy dispersive X-ray (SEM-EDX), Fourier transform infrared (FTIR), transmission electron microscopy (TEM), X-ray diffraction (XRD), ultraviolet visible (UV-Vis) and X-ray photoelectron spectroscopy (XPS) were adopted for characterizing the solid powder material. The synthesized material was found to be rich in key functional groups such as –COOH and –OH playing important roles in binding the adsorbate particles through ligand-to-metal charge transfer (LMCT). Based on the preliminary results, adsorption experiments were conducted, and the data obtained were applied to four different adsorption isotherm models, viz the Langmuir, Temkin, Freundlich and D–R models. Based on the high values of R2 and low values of χ2, the Langmuir isotherm model was found to be the best model for simulation of data for Pb (II) adsorption by XGFO. The value of maximum monolayer adsorption capacity (Qm) was found to be 117.45 mg g−1 at 303 K, 126.23 mg g−1 at 313 K, 145.12 mg g−1 at 323 K and 191.27 mg g−1 at 323 K. The kinetics of the adsorption process of Pb (II) by XGFO was best defined by the pseudo-second-order model. The thermodynamic aspect of the reaction suggested that the reaction is endothermic and spontaneous. The outcomes proved that XGFO can be utilized as an efficient adsorbent material for the treatment of contaminated wastewater. [ABSTRACT FROM AUTHOR]

Molecularly imprinted plasmonic nanosensors are robust devices capable of selective target interaction, and in some cases reaction catalysis. Recent advances in control of nanoscale structure have opened the door for development of a wide range of chemosensors for environmental monitoring. The soaring rate of environmental pollution through human activities and its negative impact on the ecosystem demands an urgent interest in developing rapid and efficient techniques that can easily be deployed for in-field assessment and environmental monitoring purposes. Organophosphate pesticides (OPPs) play a significant role for agricultural use; however, they also present environmental threats to human health due to their chemical toxicity. Plasmonic sensors are thus vital analytical detection tools that have been explored for many environmental applications and OPP detection due to their excellent properties such as high sensitivity, selectivity, and rapid recognition capability. Molecularly imprinted polymers (MIPs) have also significantly been recognized as a highly efficient, low-cost, and sensitive synthetic sensing technique that has been adopted for environmental monitoring of a wide array of environmental contaminants, specifically for very small molecule detection. In this review, the general concept of MIPs and their synthesis, a summary of OPPs and environmental pollution, plasmonic sensing with MIPs, surface plasmon resonance (SPR), surface-enhanced Raman spectroscopy (SERS) MIP sensors, and nanomaterial-based sensors for environmental monitoring applications and OPP detection have been elucidated according to the recent literature. In addition, a conclusion and future perspectives section at the end summarizes the scope of molecularly imprinted plasmonic sensors for environmental applications. [ABSTRACT FROM AUTHOR]