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154 results on '"Saeed, Hina"'

5. Skin Brachytherapy: Overview

Author

Kasper, Michael E., Saeed, Hina, Joseph, Kurian Jones, editor, Veness, Michael J., editor, Barnes, Elizabeth, editor, and Rembielak, Agata, editor

Published
2023
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8. Treatment of Oligometastatic Non-Small Cell Lung Cancer: An ASTRO/ESTRO Clinical Practice Guideline

Author

Iyengar, Puneeth, All, Sean, Berry, Mark F., Boike, Thomas P., Bradfield, Lisa, Dingemans, Anne-Marie C., Feldman, Jill, Gomez, Daniel R., Hesketh, Paul J., Jabbour, Salma K., Jeter, Melenda, Josipovic, Mirjana, Lievens, Yolande, McDonald, Fiona, Perez, Bradford A., Ricardi, Umberto, Ruffini, Enrico, De Ruysscher, Dirk, Saeed, Hina, Schneider, Bryan J., Senan, Suresh, Widder, Joachim, and Guckenberger, Matthias

Published
2023
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9. Radiation Fractionation Schedules Published During the COVID-19 Pandemic: A Systematic Review of the Quality of Evidence and Recommendations for Future Development

Author

Thomson, David J, Yom, Sue S, Saeed, Hina, El Naqa, Issam, Ballas, Leslie, Bentzen, Soren M, Chao, Samuel T, Choudhury, Ananya, Coles, Charlotte E, Dover, Laura, Guadagnolo, B Ashleigh, Guckenberger, Matthias, Hoskin, Peter, Jabbour, Salma K, Katz, Matthew S, Mukherjee, Somnath, Rembielak, Agata, Sebag-Montefiore, David, Sher, David J, Terezakis, Stephanie A, Thomas, Toms V, Vogel, Jennifer, and Estes, Christopher

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Mind and Body, Clinical Research, Good Health and Well Being, COVID-19, Coronavirus Infections, Dose Fractionation, Radiation, Evidence-Based Medicine, Humans, Pandemics, Pneumonia, Viral, Publications, Other Physical Sciences, Clinical Sciences, Oncology & Carcinogenesis, Oncology and carcinogenesis, Theoretical and computational chemistry, Medical and biological physics
Abstract

PurposeNumerous publications during the COVID-19 pandemic recommended the use of hypofractionated radiation therapy. This project assessed aggregate changes in the quality of the evidence supporting these schedules to establish a comprehensive evidence base for future reference and highlight aspects for future study.Methods and materialsBased on a systematic review of published recommendations related to dose fractionation during the COVID-19 pandemic, 20 expert panelists assigned to 14 disease groups named and graded the highest quality of evidence schedule(s) used routinely for each condition and also graded all COVID-era recommended schedules. The American Society for Radiation Oncology quality of evidence criteria were used to rank the schedules. Process-related statistics and changes in distributions of quality ratings of the highest-rated versus recommended COVID-19 era schedules were described by disease groups and for specific clinical scenarios.ResultsFrom January to May 2020 there were 54 relevant publications, including 233 recommended COVID-19-adapted dose fractionations. For site-specific curative and site-specific palliative schedules, there was a significant shift from established higher-quality evidence to lower-quality evidence and expert opinions for the recommended schedules (P = .022 and P < .001, respectively). For curative-intent schedules, the distribution of quality scores was essentially reversed (highest levels of evidence "pre-COVID" vs "in-COVID": high quality, 51.4% vs 4.8%; expert opinion, 5.6% vs 49.3%), although there was variation in the magnitude of shifts between disease sites and among specific indications.ConclusionsA large number of publications recommended hypofractionated radiation therapy schedules across numerous major disease sites during the COVID-19 pandemic, which were supported by a lower quality of evidence than the highest-quality routinely used dose fractionation schedules. This work provides an evidence-based assessment of these potentially practice-changing recommendations and informs individualized decision-making and counseling of patients. These data could also be used to support radiation therapy practices in the event of second waves or surges of the pandemic in new regions of the world.

Published
2020

16. Quantifying the Dosimetric Impact of Proton Range Uncertainties on RBE-Weighted Dose Distributions in Intensity-Modulated Proton Therapy for Bilateral Head and Neck Cancer.

Author

Rana, Suresh, Manthala Padannayil, Noufal, Tran, Linh, Rosenfeld, Anatoly B., Saeed, Hina, and Kasper, Michael

Subjects
HEAD & neck cancer, MEDICAL dosimetry, PROTON therapy, PROTONS, BRACHIAL plexus
Abstract

Background: In current clinical practice, intensity-modulated proton therapy (IMPT) head and neck cancer (HNC) plans are generated using a constant relative biological effectiveness (cRBE) of 1.1. The primary goal of this study was to explore the dosimetric impact of proton range uncertainties on RBE-weighted dose (RWD) distributions using a variable RBE (vRBE) model in the context of bilateral HNC IMPT plans. Methods: The current study included the computed tomography (CT) datasets of ten bilateral HNC patients who had undergone photon therapy. Each patient's plan was generated using three IMPT beams to deliver doses to the CTV_High and CTV_Low for doses of 70 Gy(RBE) and 54 Gy(RBE), respectively, in 35 fractions through a simultaneous integrated boost (SIB) technique. Each nominal plan calculated with a cRBE of 1.1 was subjected to the range uncertainties of ±3%. The McNamara vRBE model was used for RWD calculations. For each patient, the differences in dosimetric metrices between the RWD and nominal dose distributions were compared. Results: The constrictor muscles, oral cavity, parotids, larynx, thyroid, and esophagus showed average differences in mean dose (Dmean) values up to 6.91 Gy(RBE), indicating the impact of proton range uncertainties on RWD distributions. Similarly, the brachial plexus, brain, brainstem, spinal cord, and mandible showed varying degrees of the average differences in maximum dose (Dmax) values (2.78–10.75 Gy(RBE)). The Dmean and Dmax to the CTV from RWD distributions were within ±2% of the dosimetric results in nominal plans. Conclusion: The consistent trend of higher mean and maximum doses to the OARs with the McNamara vRBE model compared to cRBE model highlighted the need for consideration of proton range uncertainties while evaluating OAR doses in bilateral HNC IMPT plans. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Can I Leave? Perspectives on Parental Leave and Parenthood in Medical Training Among Program Directors and Trainees in Oncologic Specialties

Author

Beltrán Ponce, Sara, primary, Jagsi, Reshma, additional, Florez, Narjust, additional, Thomas, Charles R., additional, Banerjee, Anjishnu, additional, Jasti, Shravya, additional, Bailey, Morgan M., additional, Lawton, Colleen A.F., additional, Johnstone, Candice, additional, Clarke, Callisia N., additional, Bedi, Meena, additional, Jovanovic, Mirjana, additional, and Saeed, Hina, additional

Published
2024
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26. Treatment of Oligometastatic Non-Small Cell Lung Cancer:An ASTRO/ESTRO Clinical Practice Guideline

Author

Iyengar, Puneeth, All, Sean, Berry, Mark F., Boike, Thomas P., Bradfield, Lisa, Dingemans, Anne Marie C., Feldman, Jill, Gomez, Daniel R., Hesketh, Paul J., Jabbour, Salma K., Jeter, Melenda, Josipovic, Mirjana, Lievens, Yolande, McDonald, Fiona, Perez, Bradford A., Ricardi, Umberto, Ruffini, Enrico, De Ruysscher, Dirk, Saeed, Hina, Schneider, Bryan J., Senan, Suresh, Widder, Joachim, Guckenberger, Matthias, Iyengar, Puneeth, All, Sean, Berry, Mark F., Boike, Thomas P., Bradfield, Lisa, Dingemans, Anne Marie C., Feldman, Jill, Gomez, Daniel R., Hesketh, Paul J., Jabbour, Salma K., Jeter, Melenda, Josipovic, Mirjana, Lievens, Yolande, McDonald, Fiona, Perez, Bradford A., Ricardi, Umberto, Ruffini, Enrico, De Ruysscher, Dirk, Saeed, Hina, Schneider, Bryan J., Senan, Suresh, Widder, Joachim, and Guckenberger, Matthias

Abstract

Purpose: This joint guideline by American Society for Radiation Oncology (ASTRO) and the European Society for Radiotherapy and Oncology (ESTRO) was initiated to review evidence and provide recommendations regarding the use of local therapy in the management of extracranial oligometastatic non-small cell lung cancer (NSCLC). Local therapy is defined as the comprehensive treatment of all known cancer—primary tumor, regional nodal metastases, and metastases—with definitive intent. Methods: ASTRO and ESTRO convened a task force to address 5 key questions focused on the use of local (radiation, surgery, other ablative methods) and systemic therapy in the management of oligometastatic NSCLC. The questions address clinical scenarios for using local therapy, sequencing and timing when integrating local with systemic therapies, radiation techniques critical for oligometastatic disease targeting and treatment delivery, and the role of local therapy for oligoprogression or recurrent disease. Recommendations were based on a systematic literature review and created using ASTRO guidelines methodology. Results: Based on the lack of significant randomized phase 3 trials, a patient-centered, multidisciplinary approach was strongly recommended for all decision-making regarding potential treatment. Integration of definitive local therapy was only relevant if technically feasible and clinically safe to all disease sites, defined as 5 or fewer distinct sites. Conditional recommendations were given for definitive local therapies in synchronous, metachronous, oligopersistent, and oligoprogressive conditions for extracranial disease. Radiation and surgery were the only primary definitive local therapy modalities recommended for use in the management of patients with oligometastatic disease, with indications provided for choosing one over the other. Sequencing recommendations were provided for systemic and local therapy integration. Finally, multiple recommendations were provided for the

Published
2023

31. First multicentre experience of SABR for lymph node and liver oligometastatic disease on the unity MR-Linac

Author

Janssen, Tomas M., primary, Aitken, Katharine, additional, Alongi, Filippo, additional, Barry, Aisling, additional, Bernchou, Uffe, additional, Boeke, Simon, additional, Hall, William A., additional, Hosni, Ali, additional, Kroon, Petra.S., additional, Nachbar, Marcel, additional, Saeed, Hina, additional, Jürgenliemk-Schulz, Ina M., additional, Schytte, Tine, additional, Verkooijen, Helena M., additional, and Nowee, Marlies.E., additional

Published
2022
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32. Expression Characteristics and Significant Diagnostic and Prognostic Values of ANLN in Human Cancers

Author

Ahmad,Mukhtiar, Khan,Mehran, Asif,Rizwan, Sial,Nuzhat, Abid,Usman, Shamim,Tahira, Hameed,Zahid, Iqbal,Muhammad Junaid, Sarfraz,Uroosa, Saeed,Hina, Asghar,Zara, Akram,Madeeha, Ullah,Qamar, Younas,Qurat ul Ain, Rauf,Laraib, Hadi,Alishba, Maryam,Sajida, Hameed,Yasir, Khan,Muhammad Rashid, Tariq,Eman, Saeed,Saba, Ahmad,Mukhtiar, Khan,Mehran, Asif,Rizwan, Sial,Nuzhat, Abid,Usman, Shamim,Tahira, Hameed,Zahid, Iqbal,Muhammad Junaid, Sarfraz,Uroosa, Saeed,Hina, Asghar,Zara, Akram,Madeeha, Ullah,Qamar, Younas,Qurat ul Ain, Rauf,Laraib, Hadi,Alishba, Maryam,Sajida, Hameed,Yasir, Khan,Muhammad Rashid, Tariq,Eman, and Saeed,Saba

Abstract

Mukhtiar Ahmad,1,&ast; Mehran Khan,2,&ast; Rizwan Asif,3,&ast; Nuzhat Sial,4,&ast; Usman Abid,5,&ast; Tahira Shamim,6 Zahid Hameed,7 Muhammad Junaid Iqbal,8,&ast; Uroosa Sarfraz,8 Hina Saeed,1,&ast; Zara Asghar,2 Madeeha Akram,2 Qamar Ullah,9 Qurat ul Ain Younas,10 Laraib Rauf,11 Alishba Hadi,1 Sajida Maryam,12 Yasir Hameed,1 Muhammad Rashid Khan,13,&ast; Eman Tariq,14 Saba Saeed15,&ast; 1Department of Biochemistry and Biotechnology, Islamia University of Bahawalpur, Bahawalpur, Pakistan; 2Department of Pharmacy, Islamia University of Bahawalpur, Bahawalpur, Pakistan; 3Department of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan; 4Department of Zoology, Islamia University of Bahawalpur, Bahawalpur, Pakistan; 5Department of Pharmaceutics, Bahauddin Zakariya University, Multan, Pakistan; 6University College of Conventional Medicine, Islamia University of Bahawalpur, Bahawalpur, Pakistan; 7Department of Bioinformatics and Biotechnology, International Islamic University, Islamabad, Pakistan; 8Department of Biosciences, COMSATS University Islamabad, Islamabad, Pakistan; 9Department of Livestock and Dairy Development, Peshawar, Pakistan; 10Department of Zoology, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan; 11Department of Healthcare Management, Riphah International University, Islamabad, Pakistan; 12Arid Agriculture University, Rawalpindi, Pakistan; 13University College of Eastern Medicine, Islamia University of Bahawalpur, Bahawalpur, Pakistan; 14Department of Chemistry, University of Swabi, Swabi, Pakistan; 15Department of Zoology, University of the Punjab, Lahore, Pakistan&ast;These authors contributed equally to this workCorrespondence: Yasir Hameed, Department of Biochemistry and Biotechnology, Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan, Email Yasirhameed2011@gmail.comIntroduction: In light of the increased demand for reliable cancer-associated bio

Published
2022

35. Expression Characteristics and Significant Diagnostic and Prognostic Values of ANLN in Human Cancers

Author

Ahmad, Mukhtiar, primary, Khan, Mehran, additional, Asif, Rizwan, additional, Sial, Nuzhat, additional, Abid, Usman, additional, Shamim, Tahira, additional, Hameed, Zahid, additional, Iqbal, Muhammad Junaid, additional, Sarfraz, Uroosa, additional, Saeed, Hina, additional, Asghar, Zara, additional, Akram, Madeeha, additional, Ullah, Qamar, additional, Younas, Qurat ul Ain, additional, Rauf, Laraib, additional, Hadi, Alishba, additional, Maryam, Sajida, additional, Hameed, Yasir, additional, Khan, Muhammad Rashid, additional, Tariq, Eman, additional, and Saeed, Saba, additional

Published
2022
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37. Congenital combined eyelid imbrication and floppy eyelid syndrome

Author

Thabit Ali Abduallah Mustafa Odat and Janet Saeed Hina

Subjects
Eyelid imbrication syndrome, Floppy eyelid syndrome, Congenital, Eyelid disorder, Idiopathic acquired syndrome, Ophthalmology, RE1-994, Optics. Light, QC350-467
Abstract

Eyelid imbrication syndrome is an idiopathic acquired eyelid disorder characterized by upper eyelids overriding the lower eyelids. Congenital eyelid imbrications syndrome is extremely rare and thorough review of literature revealed only two previously reported cases and one congenital combined eyelid imbrications and floppy eyelid syndrome. We report a third case of bilateral asymmetric congenital eyelid imbrication syndrome and a second case of congenital combined eyelid imbrication and floppy eyelid syndrome that resolved with conservative treatment.

Published
2010
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38. Integration of quantitative imaging biomarkers in clinical trials for MR-guided radiotherapy: Conceptual guidance for multicentre studies from the MR-Linac Consortium Imaging Biomarker Working Group

Author

van Houdt, Petra J., primary, Saeed, Hina, additional, Thorwarth, Daniela, additional, Fuller, Clifton D., additional, Hall, William A., additional, McDonald, Brigid A., additional, Shukla-Dave, Amita, additional, Kooreman, Ernst S., additional, Philippens, Marielle E.P., additional, van Lier, Astrid L.H.M.W., additional, Keesman, Rick, additional, Mahmood, Faisal, additional, Coolens, Catherine, additional, Stanescu, Teodor, additional, Wang, Jihong, additional, Tyagi, Neelam, additional, Wetscherek, Andreas, additional, and van der Heide, Uulke A., additional

Published
2021
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39. Integration of quantitative imaging biomarkers in clinical trials for MR-guided radiotherapy: Conceptual guidance for multicentre studies from the MR-Linac Consortium Imaging Biomarker Working Group

Author

Houdt, Petra J. van, Saeed, Hina, Thorwarth, D., Fuller, Clifton D., Hall, W.A., McDonald, Brigid A., Keesman, R., Wetscherek, A., Heide, Uulke A. van der, Houdt, Petra J. van, Saeed, Hina, Thorwarth, D., Fuller, Clifton D., Hall, W.A., McDonald, Brigid A., Keesman, R., Wetscherek, A., and Heide, Uulke A. van der

Abstract

Contains fulltext : 236891.pdf (Publisher’s version ) (Closed access)

Published
2021

40. Integration of quantitative imaging biomarkers in clinical trials for MR-guided radiotherapy: Conceptual guidance for multicentre studies from the MR-Linac Consortium Imaging Biomarker Working Group

Author

Klinische Fysica RT, Cancer, van Houdt, Petra J., Saeed, Hina, Thorwarth, Daniela, Fuller, Clifton D., Hall, William A., McDonald, Brigid A., Shukla-Dave, Amita, Kooreman, Ernst S., Philippens, Marielle E.P., van Lier, Astrid L.H.M.W., Keesman, Rick, Mahmood, Faisal, Coolens, Catherine, Stanescu, Teodor, Wang, Jihong, Tyagi, Neelam, Wetscherek, Andreas, van der Heide, Uulke A., Klinische Fysica RT, Cancer, van Houdt, Petra J., Saeed, Hina, Thorwarth, Daniela, Fuller, Clifton D., Hall, William A., McDonald, Brigid A., Shukla-Dave, Amita, Kooreman, Ernst S., Philippens, Marielle E.P., van Lier, Astrid L.H.M.W., Keesman, Rick, Mahmood, Faisal, Coolens, Catherine, Stanescu, Teodor, Wang, Jihong, Tyagi, Neelam, Wetscherek, Andreas, and van der Heide, Uulke A.

Published
2021

44. QOLP-01. OUTCOME ASSESSMENT OF MULTIDISCIPLINARY BRAIN TUMOR BOARD MEETING RECOMMENDATIONS FOR BRAIN METASTASIS: IS THERE A GAP?

Author

Santos-Pinheiro, Fernando, primary, Bovi, Joseph, additional, Peltier, Wendy, additional, Connelly, Jennifer, additional, Mueller, Wade, additional, Straza, Michael, additional, Puckett, Lindsay, additional, Crabb, Marianne, additional, Leuck, Julianne, additional, Zwagerman, Nathan, additional, Thompson, Jonathan, additional, Schultz, Christopher, additional, Lindstedt, Jennifer, additional, Roller-Voigt, Kimberly, additional, Nelson, Ariel, additional, Bichler, Sarah, additional, Leutenegger, Alexandra, additional, Erlitz, Tracy, additional, Brausch, Carolyn, additional, Saeed, Hina, additional, Hahn, Dustin, additional, and Santos-Pinheiro, Fernando, additional

Published
2020
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46. Readdressing the Needs of Cancer Survivors During COVID-19: A Path Forward.

Author

Jones, Jennifer M, Saeed, Hina, Katz, Matthew S, Lustberg, Maryam B, Forster, Victoria J, and Nekhlyudov, Larissa

Subjects
*COVID-19, *CANCER survivors, *MEDICAL needs assessment, *MEDICAL care, *PANDEMICS
Abstract

The growing number of cancer survivors and the high prevalence of cancer-related physical and psychosocial effects pose important and pressing challenges to health systems. The coronavirus disease 2019 (COVID-19) pandemic has led to further stressors on cancer survivors and health care systems. As the pandemic continues to have substantial impact on the world, it is critical to focus attention on the health care needs of cancer survivors. In this commentary, we propose an adoption of essential steps that should be part of a continuous adaptive approach to promote effective cancer survivorship care during ongoing COVID-19 waves and beyond. [ABSTRACT FROM AUTHOR]

Published
2021
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