Search

Your search keyword '"Pauly, V."' showing total 285 results
Start Over Author "Pauly, V." Search Limiters Academic (Peer-Reviewed) Journals
285 results on '"Pauly, V."'

5. Diabetes and chronic kidney disease synergistically contribute to left ventricular diastolic dysfunction and coronary microvascular disease in swine

Author

Hamers, J, primary, Sittig, T, additional, Bierschenk, S, additional, D'alessio, C, additional, Zhang, H, additional, Clauss, S, additional, Schuettler, D, additional, Tomsits, P, additional, Vlcek, J, additional, Pauly, V, additional, Hesse, N, additional, Sen, P, additional, and Merkus, D, additional

Published
2023
Full Text
View/download PDF

27. Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19

Author

Cauchois, R., Koubi, M., Delarbre, D., Manet, C., Carvelli, J., Blasco, V.B., Jean, R., Fouche, L., Bornet, C., Pauly, V., Mazodier, K., Pestre, V., Jarrot, P.A., Dinarello, C.A., Kaplanski, G., Cauchois, R., Koubi, M., Delarbre, D., Manet, C., Carvelli, J., Blasco, V.B., Jean, R., Fouche, L., Bornet, C., Pauly, V., Mazodier, K., Pestre, V., Jarrot, P.A., Dinarello, C.A., and Kaplanski, G.

Abstract

Contains fulltext : 229588.pdf (Publisher’s version ) (Open Access), Around the tenth day after diagnosis, ∼20% of patients with coronavirus disease 2019 (COVID-19)-associated pneumonia evolve toward severe oxygen dependence (stage 2b) and acute respiratory distress syndrome (stage 3) associated with systemic inflammation often termed a "cytokine storm." Because interleukin-1 (IL-1) blocks the production of IL-6 and other proinflammatory cytokines, we treated COVID-19 patients early in the disease with the IL-1 receptor antagonist, anakinra. We retrospectively compared 22 patients from three different centers in France with stages 2b and 3 COVID-19-associated pneumonia presenting with acute severe respiratory failure and systemic inflammation who received either standard-of-care treatment alone (10 patients) or combined with intravenous anakinra (12 patients). Treatment started at 300 mg⋅d(-1) for 5 d, then tapered with lower dosing over 3 d. Both populations were comparable for age, comorbidities, clinical stage, and elevated biomarkers of systemic inflammation. All of the patients treated with anakinra improved clinically (P < 0.01), with no deaths, significant decreases in oxygen requirements (P < 0.05), and more days without invasive mechanical ventilation (P < 0.06), compared with the control group. The effect of anakinra was rapid, as judged by significant decrease of fever and C-reactive protein at day 3. A mean total dose of 1,950 mg was infused with no adverse side effects or bacterial infection. We conclude that early blockade of the IL-1 receptor is therapeutic in acute hyperinflammatory respiratory failure in COVID-19 patients.

Published
2020

40. Effets uronéphrologiques des produits utilisés par les usagers de drogues : revue de la littérature et enquête pharmacoépidémiologique en France et dans la région de Marseille

Author

Gully, M., primary, Frauger, E., additional, Spadari, M., additional, Pauly, V., additional, Romain, F., additional, Burtey, S., additional, Sallée, M., additional, Daniel, L., additional, Moussi-Francès, J., additional, Dussol, B., additional, Micallef, J., additional, and Jourde-Chiche, N., additional

Published
2017
Full Text
View/download PDF

44. Contribution of MRI in the diagnosis of traumatic ruptures of the anterior cruciate ligament

Author

Guenoun, D., Le Corroller, T., Amous, Z., Pauly, V., Sbihi, A., Champsaur, P., Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Institut des Sciences du Mouvement Etienne Jules Marey (ISM), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Clinique Juge - Clinique du sport [Marseille], and Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Tear, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Knee, musculoskeletal system, Anterior cruciate ligament, human activities, MRI
Abstract

International audience; When faced with a clinical suspicion of knee ligament injury, MRI nowadays has a central role in the diagnostic strategy. In particular, it is essential for assessing the cruciate ligaments and any associated meniscal tears. The objective of this review is to present the various direct and indirect MRI signs of tearing of the anterior cruciate ligament (ACL) and then describe the lesions associated with it. The anatomical and clinical aspects are also discussed so that the contribution of MRI to the diagnosis and therapeutic management of an ACL tear can be better understood.

Published
2012

Catalog

Books, media, physical & digital resources
See catalog results