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143 results on '"Openshaw, Peter J M"'

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1. Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

2. Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus

3. Accelerated immune ageing is associated with COVID-19 disease severity

4. Changes in hospital mortality in patients with cancer during the COVID-19 pandemic (ISARIC-CCP-UK): a prospective, multicentre cohort study

5. Reframing sepsis immunobiology for translation: towards informative subtyping and targeted immunomodulatory therapies

7. Obesity dysregulates the pulmonary antiviral immune response

8. The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection

9. GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

10. Comparison of UK paediatric SARS-CoV-2 admissions across the first and second pandemic waves

11. Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

12. Whole-genome sequencing reveals host factors underlying critical COVID-19

13. Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

14. Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

15. Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19.

16. Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

17. Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom : prospective multicentre observational cohort study

18. Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

19. Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

20. Outcome of COVID-19 in hospitalised immunocompromised patients: An analysis of the WHO ISARIC CCP-UK prospective cohort study

21. Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

23. Tracheostomy in the COVID-19 era: global and multidisciplinary guidance

25. A haemagglutination test for rapid detection of antibodies to SARS-CoV-2

26. A Genome-Wide Association Study of Respiratory Syncytial Virus Infection Severity in Infants.

27. Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults.

28. Natural killer cells and innate lymphoid cells but not NKT cells are mature in their cytokine production at birth.

30. Single‐cell immune profiling reveals markers of emergency myelopoiesis that distinguish severe from mild respiratory syncytial virus disease in infants.

31. T cells, more than antibodies, may prevent symptoms developing from respiratory syncytial virus infections in older adults.

32. SARS-CoV-2 infection is associated with anti-desmoglein 2 autoantibody detection.

33. Respiratory viruses: New frontiers—a Keystone Symposia report.

34. Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19.

35. Fewer COVID‐19 Neurological Complications with Dexamethasone and Remdesivir.

37. Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study.

40. Impact of cardiometabolic multimorbidity and ethnicity on cardiovascular/renal complications in patients with COVID-19.

41. Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other Lineages.

43. Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission.

44. Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers.

46. Outcomes of Coronavirus Disease 2019 (COVID-19) Related Hospitalization Among People With Human Immunodeficiency Virus (HIV) in the ISARIC World Health Organization (WHO) Clinical Characterization Protocol (UK): A Prospective Observational Study.

50. Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK.

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