356 results on '"Kinast, A."'
Search Results
2. Detector Development for the CRESST Experiment
- Author
-
Angloher, G., Banik, S., Benato, G., Bento, A., Bertolini, A., Breier, R., Bucci, C., Burkhart, J., Canonica, L., D’Addabbo, A., Di Lorenzo, S., Einfalt, L., Erb, A., Feilitzsch, F. V., Fichtinger, S., Fuchs, D., Garai, A., Ghete, V. M., Gorla, P., Guillaumon, P. V., Gupta, S., Hauff, D., Ješkovský, M., Jochum, J., Kaznacheeva, M., Kinast, A., Kluck, H., Kraus, H., Kuckuk, S., Langenkämper, A., Mancuso, M., Marini, L., Mauri, B., Meyer, L., Mokina, V., Olmi, M., Ortmann, T., Pagliarone, C., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl, F., Rothe, J., Schäffner, K., Schieck, J., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Willers, M., and Zema, V.
- Published
- 2024
- Full Text
- View/download PDF
3. Optimal Operation of Cryogenic Calorimeters Through Deep Reinforcement Learning
- Author
-
Angloher, G., Banik, S., Benato, G., Bento, A., Bertolini, A., Breier, R., Bucci, C., Burkhart, J., Canonica, L., D’Addabbo, A., Di Lorenzo, S., Einfalt, L., Erb, A., v. Feilitzsch, F., Fichtinger, S., Fuchs, D., Garai, A., Ghete, V. M., Gorla, P., Guillaumon, P. V., Gupta, S., Hauff, D., Ješkovský, M., Jochum, J., Kaznacheeva, M., Kinast, A., Kuckuk, S., Kluck, H., Kraus, H., Langenkämper, A., Mancuso, M., Marini, L., Mauri, B., Meyer, L., Mokina, V., Niedermayer, K., Olmi, M., Ortmann, T., Pagliarone, C., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl, F., Rothe, J., Schäffner, K., Schieck, J., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Wagner, V., Willers, M., Zema, V., Heitzinger, C., and Waltenberger, W.
- Published
- 2024
- Full Text
- View/download PDF
4. Light dark matter search using a diamond cryogenic detector
- Author
-
CRESST Collaboration, G. Angloher, S. Banik, G. Benato, A. Bento, A. Bertolini, R. Breier, C. Bucci, J. Burkhart, L. Canonica, A. D’Addabbo, S. Di Lorenzo, L. Einfalt, A. Erb, F. v. Feilitzsch, S. Fichtinger, D. Fuchs, A. Garai, V. M. Ghete, P. Gorla, P. V. Guillaumon, S. Gupta, D. Hauff, M. Jes̆kovský, J. Jochum, M. Kaznacheeva, A. Kinast, H. Kluck, H. Kraus, S. Kuckuk, A. Langenkämper, M. Mancuso, L. Marini, B. Mauri, L. Meyer, V. Mokina, M. Olmi, T. Ortmann, C. Pagliarone, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Pucci, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, M. Willers, and V. Zema
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract Diamond operated as a cryogenic calorimeter is an excellent target for direct detection of low-mass dark matter candidates. Following the realization of the first low-threshold cryogenic detector that uses diamond as absorber for astroparticle physics applications, we now present the resulting exclusion limits on the elastic spin-independent interaction cross-section of dark matter with diamond. We measured two 0.175 g CVD (Chemical Vapor Deposition) diamond samples, each instrumented with a Transition Edge Sensor made of Tungsten (W-TES). Thanks to the energy threshold of just 16.8 eV of one of the two detectors, we set exclusion limits on the elastic spin-independent interaction of dark matter particles with carbon nuclei down to dark matter masses as low as 0.122 GeV/c $$^2$$ 2 . This work shows the scientific potential of cryogenic detectors made from diamond and lays the foundation for the use of this material as target for direct detection dark matter experiments.
- Published
- 2024
- Full Text
- View/download PDF
5. A plastic scintillation muon veto for sub-Kelvin temperatures
- Author
-
A. Erhart, V. Wagner, A. Wex, C. Goupy, D. Lhuillier, E. Namuth, C. Nones, R. Rogly, V. Savu, M. Schwarz, R. Strauss, M. Vivier, H. Abele, G. Angloher, A. Bento, J. Burkhart, L. Canonica, F. Cappella, N. Casali, R. Cerulli, A. Cruciani, G. del Castello, M. del Gallo Roccagiovine, A. Doblhammer, S. Dorer, M. Friedl, A. Garai, V. M. Ghete, D. Hauff, F. Jeanneau, E. Jericha, M. Kaznacheeva, A. Kinast, H. Kluck, A. Langenkämper, T. Lasserre, M. Mancuso, R. Martin, B. Mauri, A. Mazzolari, E. Mazzucato, H. Neyrial, L. Oberauer, T. Ortmann, L. Pattavina, L. Peters, F. Petricca, W. Potzel, F. Pröbst, F. Pucci, F. Reindl, M. Romagnoni, J. Rothe, N. Schermer, J. Schieck, S. Schönert, C. Schwertner, L. Scola, G. Soum-Sidikov, L. Stodolsky, M. Tamisari, C. Tomei, and M. Vignati
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract Rare-event search experiments located on-surface, such as short-baseline reactor neutrino experiments, are often limited by muon-induced background events. Highly efficient muon vetos are essential to reduce the detector background and to reach the sensitivity goals. We demonstrate the feasibility of deploying organic plastic scintillators at sub-Kelvin temperatures. For the NUCLEUS experiment, we developed a cryogenic muon veto equipped with wavelength shifting fibers and a silicon photo multiplier operating inside a dilution refrigerator. The achievable compactness of cryostat-internal integration is a key factor in keeping the muon rate to a minimum while maximizing coverage. The thermal and light output properties of a plastic scintillation detector were examined. We report first data on the thermal conductivity and heat capacity of the polystyrene-based scintillator UPS-923A over a wide range of temperatures extending below one Kelvin. The light output was measured down to 0.8 K and observed to increase by a factor of 1.61 ± 0.05 compared to 300 K. The development of an organic plastic scintillation muon veto operating in sub-Kelvin temperature environments opens new perspectives for rare-event searches with cryogenic detectors at sites lacking substantial overburden.
- Published
- 2024
- Full Text
- View/download PDF
6. Light dark matter search using a diamond cryogenic detector
- Author
-
Angloher, G., Banik, S., Benato, G., Bento, A., Bertolini, A., Breier, R., Bucci, C., Burkhart, J., Canonica, L., D’Addabbo, A., Lorenzo, S. Di, Einfalt, L., Erb, A., Feilitzsch, F. v., Fichtinger, S., Fuchs, D., Garai, A., Ghete, V. M., Gorla, P., Guillaumon, P. V., Gupta, S., Hauff, D., Jes̆kovský, M., Jochum, J., Kaznacheeva, M., Kinast, A., Kluck, H., Kraus, H., Kuckuk, S., Langenkämper, A., Mancuso, M., Marini, L., Mauri, B., Meyer, L., Mokina, V., Olmi, M., Ortmann, T., Pagliarone, C., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl, F., Rothe, J., Schäffner, K., Schieck, J., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Willers, M., and Zema, V.
- Published
- 2024
- Full Text
- View/download PDF
7. A plastic scintillation muon veto for sub-Kelvin temperatures
- Author
-
Erhart, A., Wagner, V., Wex, A., Goupy, C., Lhuillier, D., Namuth, E., Nones, C., Rogly, R., Savu, V., Schwarz, M., Strauss, R., Vivier, M., Abele, H., Angloher, G., Bento, A., Burkhart, J., Canonica, L., Cappella, F., Casali, N., Cerulli, R., Cruciani, A., del Castello, G., del Gallo Roccagiovine, M., Doblhammer, A., Dorer, S., Friedl, M., Garai, A., Ghete, V. M., Hauff, D., Jeanneau, F., Jericha, E., Kaznacheeva, M., Kinast, A., Kluck, H., Langenkämper, A., Lasserre, T., Mancuso, M., Martin, R., Mauri, B., Mazzolari, A., Mazzucato, E., Neyrial, H., Oberauer, L., Ortmann, T., Pattavina, L., Peters, L., Petricca, F., Potzel, W., Pröbst, F., Pucci, F., Reindl, F., Romagnoni, M., Rothe, J., Schermer, N., Schieck, J., Schönert, S., Schwertner, C., Scola, L., Soum-Sidikov, G., Stodolsky, L., Tamisari, M., Tomei, C., and Vignati, M.
- Published
- 2024
- Full Text
- View/download PDF
8. Tensions in Coopetition between Gypsy and Non-gypsy Breweries in the Light of Actornetwork Theory
- Author
-
Elisa Priori de Deus, Alexandre Borba da Silveira, Luciane Maines da Silva, and Patrícia Kinast de Camillis
- Subjects
coopetition ,relationships ,tensions ,actor-network theory ,craft brewery ,Business ,HF5001-6182 - Abstract
Objective: The search for market expansion challenges Brazilian craft breweries. Based on coopetition strategies, many join in seeking to overcome these challenges. The challenge for gypsy breweries is even more significant, as they must produce beer in a non-gypsy brewery. Some tensions emerge from this relationship, such as space availability and costs. Methods: From the actor-network theory, we analyze the relationship between gypsy and non-gypsy breweries, deepening the analysis of their tensions. Based on a case study with craft breweries in Rio de Janeiro State. Results: As the results highlighted, the tension between them starts at a level not mentioned in the literature on coopetition. Conclusions: This extension expands the existing literature on coopetition by highlighting the influence of nonhuman elements (e.g., factory, resources, equipment, and operations) in shaping inter-organizational relationships, with the factory being the main generator of this tension. The study offers insights into how actors (human and nonhuman) navigate, interact, and negotiate tensions to achieve mutual goals. By applying ANT to analyze coopetition dynamics, the study contributes to the theoretical framework by demonstrating how this approach can enhance understanding of complex mechanisms, processes, and relationships through which coopetition dynamics unfold in practice.
- Published
- 2024
- Full Text
- View/download PDF
9. Analysis of the correlation for energy deposition in PWR coolant by coupled neutron-photon transport calculations
- Author
-
Castagna, Christian, Tomatis, Daniele, Kinast, Shai, and Gilad, Erez
- Published
- 2024
- Full Text
- View/download PDF
10. Legal series and legal careers: Investigating relationships between watching the legal drama Suits and law school enrollment
- Author
-
Jochen Kinast
- Subjects
Communication. Mass media ,P87-96 - Abstract
The paper investigates whether watching legal series leads to law school enroll- ment. First, the study analyses if series consumption is related to enrolling at law school. This is achieved by analyzing data of 1,353 students from Münster, Germany. Hence, lo- gistic regressions are conducted. Thereafter, the odds ratios of studying law are compared for the periods before and after the first broadcasting of the series Suits. Results suggest that watching legal series is highly significantly related to studying law. Moreover, findings indicate that the broadcasting of Suits is followed by a rise in application and enrollment numbers at Münster Law School.
- Published
- 2023
- Full Text
- View/download PDF
11. Janus kinase-inhibition modulates hepatitis E virus infection
- Author
-
Kinast, Volker, Andreica, Ioana, Ahrenstorf, Gerrit, Gömer, André, Elsner, Carina, Schlienkamp, Sarah, Schrader, Jil Alexandra, Klöhn, Mara, Ulrich, Rainer G., Broering, Ruth, Vondran, Florian W.R., Todt, Daniel, Behrendt, Patrick, Dittmer, Ulf, Hamprecht, Axel, Witte, Torsten, Baraliakos, Xenofon, and Steinmann, Eike
- Published
- 2023
- Full Text
- View/download PDF
12. Patients with Low Vision Struggle with Placing Eye Drops and Benefit from an Eye Drop Aid
- Author
-
Grissom, Nick, Gardiner, Stuart K., Rees, Jack P., Sanchez, Facundo G., Mansberger, Steven L., Cunningham, Emmett T., Jr., Burgoyne, Claude F., Rice, Karen, Belter, Christina, and Kinast, Robert M.
- Published
- 2023
- Full Text
- View/download PDF
13. Effects of sensorineural hearing loss on formant-frequency discrimination: Measurements and models
- Author
-
Carney, Laurel H., Cameron, David A., Kinast, Kameron B., Feld, C. Evelyn, Schwarz, Douglas M., Leong, U-Cheng, and McDonough, Joyce M.
- Published
- 2023
- Full Text
- View/download PDF
14. Nucleus: Searching for Coherent Neutrino Nucleus Scattering at Lowest Energies
- Author
-
Kluck, H., Angloher, G., Bento, A., Canonica, L., Cappella, F., Cardani, L., Casali, N., Cerulli, R., Colantoni, I., Cruciani, A., del Castello, G., Erhart, A., Friedl, M., Garai, A., Ghete, V. M., Goupy, C., Guidi, V., Hauff, D., Kaznacheeva, M., Kinast, A., Klinkenberg, L., Langenkämper, A., Lasserre, T., Lhuillier, D., Mancuso, M., Mauri, B., Mazzolari, A., Mazzucato, E., Neyrial, H., Nones, C., Oberauer, L., Onillon, A., Ortmann, T., Pattavina, L., Petricca, F., Potzel, W., Pröbst, F., Pucci, F., Reindl, F., Rogly, R., Rothe, J., Savu, V., Schermer, N., Schieck, J., Schönert, S., Schwertner, C., Scola, L., Stodolsky, L., Strauss, R., Tomei, C., von Mirbach, K., Vignati, M., Vivier, M., Wagner, V., and Wex, A.
- Published
- 2022
- Full Text
- View/download PDF
15. Improving the Quality of CaWO4 Target Crystals for CRESST
- Author
-
Kinast, A., Angloher, G., Benato, G., Bento, A., Bertolini, A., Breier, R., Bucci, C., Canonica, L., D’Addabbo, A., Lorenzo, S. Di, Einfalt, L., Erb, A., Feilitzsch, F. V., Iachellini, N. Ferreiro, Fichtinger, S., Fuchs, D., Fuss, A., Garai, A., Ghete, V.-M., Gorla, P., Gupta, S., Hamilton, F., Hauff, D., Ješkovský, M., Jochum, J., Kaznacheeva, M., Kluck, H., Kraus, H., Langenkämper, A., Mancuso, M., Marini, L., Mokina, V., Nilima, A., Olmi, M., Ortmann, T., Pagliarone, C., Palušová, V., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl, F., Rothe, J., Schäffner, K., Schieck, J., Schmiedmayer, D., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Willers, M., and Zema, V.
- Published
- 2022
- Full Text
- View/download PDF
16. Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses
- Author
-
Yudi Zhang, Volker Kinast, Julie Sheldon, Nicola Frericks, Daniel Todt, Matthias Zimmer, Neva Caliskan, Richard J. P. Brown, Eike Steinmann, and Thomas Pietschmann
- Subjects
restriction factor ,HCV ,liver ,IFN ,species tropism ,virus ,Microbiology ,QR1-502 - Abstract
ABSTRACT Mice are refractory to infection with human-tropic hepatitis C virus (HCV), although distantly related rodent hepaciviruses (RHV) circulate in wild rodents. To investigate whether liver intrinsic host factors can exhibit broad restriction against these distantly related hepaciviruses, we focused on Shiftless (Shfl), an interferon (IFN)-regulated gene (IRG) which restricts HCV in humans. Unusually, and in contrast to selected classical IRGs, human and mouse SHFL orthologues (hSHFL and mSHFL, respectively) were highly expressed in hepatocytes in the absence of viral infection, weakly induced by IFN, and highly conserved at the amino acid level (>95%). Replication of both HCV and RHV subgenomic replicons was suppressed by ectopic expression of mSHFL in human or rodent hepatoma cell lines. Gene editing of endogenous mShfl in mouse liver tumor cells increased HCV replication and virion production. Colocalization of mSHFL protein with viral double-stranded RNA (dsRNA) intermediates was confirmed and could be ablated by mutational disruption of the SHFL zinc finger domain, concomitant with a loss of antiviral activity. In summary, these data point to an evolutionarily conserved function for this gene in humans and rodents: SHFL is an ancient antiviral effector which targets distantly related hepaciviruses via restriction of viral RNA replication. IMPORTANCE Viruses have evolved ways to evade or blunt innate cellular antiviral mechanisms within their cognate host species. However, these adaptations may fail when viruses infect new species and can therefore limit cross-species transmission. This may also prevent development of animal models for human-pathogenic viruses. HCV shows a narrow species tropism likely due to distinct human host factor usage and innate antiviral defenses limiting infection of nonhuman liver cells. Interferon (IFN)-regulated genes (IRGs) partially inhibit HCV infection of human cells by diverse mechanisms. Here, we show that mouse Shiftless (mSHFL), a protein that interferes with HCV replication factories, inhibits HCV replication and infection in human and mouse liver cells. We further report that the zinc finger domain of SHFL is important for viral restriction. These findings implicate mSHFL as a host factor that impairs HCV infection of mice and provide guidance for development of HCV animal models needed for vaccine development.
- Published
- 2023
- Full Text
- View/download PDF
17. Stability and bifurcation analysis of Generation IV reactors via point reactor models with temperature reactivity feedback
- Author
-
Sivan, Doron, Meron, Ehud, and Kinast, Shai
- Published
- 2023
- Full Text
- View/download PDF
18. Secular equilibrium assessment in a CaWO4 target crystal from the dark matter experiment CRESST using Bayesian likelihood normalisation
- Author
-
Angloher, G., Banik, S., Benato, G., Bento, A., Bertolini, A., Breier, R., Bucci, C., Burkhart, J., Canonica, L., D’Addabbo, A., Di Lorenzo, S., Einfalt, L., Erb, A., Feilitzsch, F.v., Ferreiro Iachellini, N., Fichtinger, S., Fuchs, D., Fuss, A., Garai, A., Ghete, V.M., Gorla, P., Gupta, S., Hauff, D., Ješkovský, M., Jochum, J., Kaznacheeva, M., Kinast, A., Kluck, H., Kraus, H., Langenkämper, A., Mancuso, M., Marini, L., Mokina, V., Nilima, A., Olmi, M., Ortmann, T., Pagliarone, C., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl, F., Rothe, J., Schäffner, K., Schieck, J., Schmiedmayer, D., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Willers, M., Zema, V., Ferella, F., Laubenstein, M., and Nisi, S.
- Published
- 2023
- Full Text
- View/download PDF
19. System for performance evaluation and calibration of low-cost gas sensors applied to air quality monitoring
- Author
-
Gamboa, Vanessa Schwarstzhaupt, Kinast, Éder Julio, and Pires, Marçal
- Published
- 2023
- Full Text
- View/download PDF
20. Towards an automated data cleaning with deep learning in CRESST
- Author
-
Angloher, G., Banik, S., Bartolot, D., Benato, G., Bento, A., Bertolini, A., Breier, R., Bucci, C., Burkhart, J., Canonica, L., D’Addabbo, A., Di Lorenzo, S., Einfalt, L., Erb, A., Feilitzsch, F. v., Iachellini, N. Ferreiro, Fichtinger, S., Fuchs, D., Fuss, A., Garai, A., Ghete, V. M., Gerster, S., Gorla, P., Guillaumon, P. V., Gupta, S., Hauff, D., Ješkovský, M., Jochum, J., Kaznacheeva, M., Kinast, A., Kluck, H., Kraus, H., Lackner, M., Langenkämper, A., Mancuso, M., Marini, L., Meyer, L., Mokina, V., Nilima, A., Olmi, M., Ortmann, T., Pagliarone, C., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl, F., Rizvanovic, D., Rothe, J., Schäffner, K., Schieck, J., Schmiedmayer, D., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Willers, M., Zema, V., and Waltenberger, W.
- Published
- 2023
- Full Text
- View/download PDF
21. Knowledge in critical events: Know-how at work of emerging country firefighters
- Author
-
Militz, Roseane, Gallon, Shalimar, Kinast De Camillis, Patrícia, Magalhães Bitencourt, Betina, and Pauli, Jandir
- Published
- 2022
- Full Text
- View/download PDF
22. Hepatitis E virus species barriers: seeking viral and host determinants
- Author
-
Kinast, Volker, Klöhn, Mara, Nocke, Maximilian K, Todt, Daniel, and Steinmann, Eike
- Published
- 2022
- Full Text
- View/download PDF
23. Clinicians’ Use of Quantitative Information while Assessing the Rate of Functional Progression in Glaucoma
- Author
-
Gardiner, Stuart K., Kinast, Robert M., De Moraes, Carlos Gustavo, Budenz, Donald L., Jeoung, Jin Wook, Lind, John T., Myers, Jonathan S., Nouri-Mahdavi, Kouros, Rhodes, Lindsay A., Strouthidis, Nicholas G., Chen, Teresa C., and Mansberger, Steven L.
- Published
- 2022
- Full Text
- View/download PDF
24. Clinicians' Use of Quantitative Information When Assessing the Rate of Structural Progression in Glaucoma
- Author
-
Gardiner, Stuart K., Kinast, Robert M., Chen, Teresa C., Strouthidis, Nicholas G., De Moraes, Carlos Gustavo, Nouri-Mahdavi, Kouros, Myers, Jonathan S., Jeoung, Jin Wook, Lind, John T., Rhodes, Lindsay A., Budenz, Donald L., and Mansberger, Steven L.
- Published
- 2022
- Full Text
- View/download PDF
25. A hybrid metaheuristic solution approach for the cobot assignment and job shop scheduling problem
- Author
-
Kinast, Alexander, Braune, Roland, Doerner, Karl F., Rinderle-Ma, Stefanie, and Weckenborg, Christian
- Published
- 2022
- Full Text
- View/download PDF
26. Functional Requirements for Medical Data Integration into Knowledge Management Environments: Requirements Elicitation Approach Based on Systematic Literature Analysis
- Author
-
Benjamin Kinast, Hannes Ulrich, Björn Bergh, and Björn Schreiweis
- Subjects
Computer applications to medicine. Medical informatics ,R858-859.7 ,Public aspects of medicine ,RA1-1270 - Abstract
BackgroundIn patient care, data are historically generated and stored in heterogeneous databases that are domain specific and often noninteroperable or isolated. As the amount of health data increases, the number of isolated data silos is also expected to grow, limiting the accessibility of the collected data. Medical informatics is developing ways to move from siloed data to a more harmonized arrangement in information architectures. This paradigm shift will allow future research to integrate medical data at various levels and from various sources. Currently, comprehensive requirements engineering is working on data integration projects in both patient care– and research-oriented contexts, and it is significantly contributing to the success of such projects. In addition to various stakeholder-based methods, document-based requirement elicitation is a valid method for improving the scope and quality of requirements. ObjectiveOur main objective was to provide a general catalog of functional requirements for integrating medical data into knowledge management environments. We aimed to identify where integration projects intersect to derive consistent and representative functional requirements from the literature. On the basis of these findings, we identified which functional requirements for data integration exist in the literature and thus provide a general catalog of requirements. MethodsThis work began by conducting a literature-based requirement elicitation based on a broad requirement engineering approach. Thus, in the first step, we performed a web-based systematic literature review to identify published articles that dealt with the requirements for medical data integration. We identified and analyzed the available literature by applying the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. In the second step, we screened the results for functional requirements using the requirements engineering method of document analysis and derived the requirements into a uniform requirement syntax. Finally, we classified the elicited requirements into a category scheme that represents the data life cycle. ResultsOur 2-step requirements elicitation approach yielded 821 articles, of which 61 (7.4%) were included in the requirement elicitation process. There, we identified 220 requirements, which were covered by 314 references. We assigned the requirements to different data life cycle categories as follows: 25% (55/220) to data acquisition, 35.9% (79/220) to data processing, 12.7% (28/220) to data storage, 9.1% (20/220) to data analysis, 6.4% (14/220) to metadata management, 2.3% (5/220) to data lineage, 3.2% (7/220) to data traceability, and 5.5% (12/220) to data security. ConclusionsThe aim of this study was to present a cross-section of functional data integration–related requirements defined in the literature by other researchers. The aim was achieved with 220 distinct requirements from 61 publications. We concluded that scientific publications are, in principle, a reliable source of information for functional requirements with respect to medical data integration. Finally, we provide a broad catalog to support other scientists in the requirement elicitation phase.
- Published
- 2023
- Full Text
- View/download PDF
27. A perturbation-based hybrid methodology for control drum worth prediction applied to the HOLOS-Quad microreactor concept
- Author
-
Price, Dean, Kinast, Shai, Barr, Kaitlyn, Kochunas, Brendan, and Filippone, Claudio
- Published
- 2022
- Full Text
- View/download PDF
28. Probing spin-dependent dark matter interactions with $$^6$$ 6 Li
- Author
-
G. Angloher, G. Benato, A. Bento, E. Bertoldo, A. Bertolini, R. Breier, C. Bucci, L. Canonica, A. D’Addabbo, S. Di Lorenzo, L. Einfalt, A. Erb, F. v. Feilitzsch, N. Ferreiro Iachellini, S. Fichtinger, D. Fuchs, A. Fuss, A. Garai, V. M. Ghete, P. Gorla, S. Gupta, D. Hauff, M. Ješkovský, J. Jochum, M. Kaznacheeva, A. Kinast, H. Kluck, H. Kraus, A. Langenkämper, M. Mancuso, L. Marini, V. Mokina, A. Nilima, M. Olmi, T. Ortmann, C. Pagliarone, V. Palušová, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Pucci, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, D. Schmiedmayer, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, M. Willers, and V. Zema
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract CRESST is one of the most prominent direct detection experiments for dark matter particles with sub-GeV/c $$^2$$ 2 mass. One of the advantages of the CRESST experiment is the possibility to include a large variety of nuclides in the target material used to probe dark matter interactions. In this work, we discuss in particular the interactions of dark matter particles with protons and neutrons of $$^{6}$$ 6 Li. This is now possible thanks to new calculations on nuclear matrix elements of this specific isotope of Li. To show the potential of using this particular nuclide for probing dark matter interactions, we used the data collected previously by a CRESST prototype based on LiAlO $$_2$$ 2 and operated in an above ground test-facility at Max-Planck-Institut für Physik in Munich, Germany. In particular, the inclusion of $$^{6}$$ 6 Li in the limit calculation drastically improves the result obtained for spin-dependent interactions with neutrons in the whole mass range. The improvement is significant, greater than two order of magnitude for dark matter masses below 1 GeV/c $$^2$$ 2 , compared to the limit previously published with the same data.
- Published
- 2022
- Full Text
- View/download PDF
29. Combining metaheuristics and process mining: Improving cobot placement in a combined cobot assignment and job shop scheduling problem
- Author
-
Kinast, Alexander, Doerner, Karl F., and Rinderle-Ma, Stefanie
- Published
- 2022
- Full Text
- View/download PDF
30. The triglyceride-synthesizing enzyme diacylglycerol acyltransferase 2 modulates the formation of the hepatitis C virus replication organelle.
- Author
-
Reichert, Isabelle, Lee, Ji-Young, Weber, Laura, Fuh, Marceline M., Schlaeger, Lina, Rößler, Stefanie, Kinast, Volker, Schlienkamp, Sarah, Conradi, Janina, Vondran, Florian W. R., Pfaender, Stephanie, Scaturro, Pietro, Steinmann, Eike, Bartenschlager, Ralf, Pietschmann, Thomas, Heeren, Joerg, Lauber, Chris, and Vieyres, Gabrielle
- Subjects
HEPATITIS C virus ,UNSATURATED fatty acids ,INTRACELLULAR membranes ,ENDOPLASMIC reticulum ,HEPATITIS C - Abstract
The replication organelle of hepatitis C virus (HCV), called membranous web, is derived from the endoplasmic reticulum (ER) and mainly comprises double membrane vesicles (DMVs) that concentrate the viral replication complexes. It also tightly associates with lipid droplets (LDs), which are essential for virion morphogenesis. In particular acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1), a rate-limiting enzyme in triglyceride synthesis, promotes early steps of virus assembly. The close proximity between ER membranes, DMVs and LDs therefore permits the efficient coordination of the HCV replication cycle. Here, we demonstrate that exaggerated LD accumulation due to the excessive expression of the DGAT1 isozyme, DGAT2, dramatically impairs the formation of the HCV membranous web. This effect depended on the enzymatic activity and ER association of DGAT2, whereas the mere LD accumulation was not sufficient to hamper HCV RNA replication. Our lipidomics data indicate that both HCV infection and DGAT2 overexpression induced membrane lipid biogenesis and markedly increased phospholipids with long chain polyunsaturated fatty acids, suggesting a dual use of these lipids and their possible competition for LD and DMV biogenesis. On the other hand, overexpression of DGAT2 depleted specific phospholipids, particularly oleyl fatty acyl chain-containing phosphatidylcholines, which, in contrast, are increased in HCV-infected cells and likely essential for viral infection. In conclusion, our results indicate that lipid exchanges occurring during LD biogenesis regulate the composition of intracellular membranes and thereby affect the formation of the HCV replication organelle. The potent antiviral effect observed in our DGAT2 overexpression system unveils lipid flux that may be relevant in the context of steatohepatitis, a hallmark of HCV infection, but also in physiological conditions, locally in specific subdomains of the ER membrane. Thus, LD formation mediated by DGAT1 and DGAT2 might participate in the spatial compartmentalization of HCV replication and assembly factories within the membranous web. Author summary: Lipid droplets are fat storage organelles with an increasingly recognized importance for the infectious cycle of multiple pathogens. In particular, they support hepatitis C virion morphogenesis and the formation of the picornaviral replication organelle. Unexpectedly, we observed that exaggerated lipid droplet biogenesis, due to an excessive expression of the triglyceride forming enzyme DGAT2, is deleterious to hepatitis C virus replication. More precisely, the formation and maintenance of the viral replication organelle was impeded. Exaggerated lipid droplet biogenesis induced by DGAT2 also profoundly altered the cell lipidome, with strong accumulation of neutral lipids and changes in the membrane lipid composition. Our results support a model where lipid flux occurring during lipid droplet biogenesis regulates the composition of the endoplasmic reticulum membranes, where lipid droplets are formed, and thereby affect the capacity of hepatitis C virus to remodel these membranes into its replication organelle. Since DGAT1 and its triglyceride synthesis were previously reported to contribute to virus assembly, this also implies that lipid droplet biogenesis driven by DGAT1 and DGAT2 but also membrane contact sites between endoplasmic reticulum and lipid droplets might locally restrict and determine the formation of hepatitis C virus replication and assembly factories. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
31. Latest observations on the low energy excess in CRESST-III
- Author
-
G. Angloher, S. Banik, G. Benato, A. Bento, A. Bertolini, R. Breier, C. Bucci, L. Canonica, A. D'Addabbo, S. Di Lorenzo, L. Einfalt, A. Erb, F. von Feilitzsch, N. Ferreiro Iachellini, S. Fichtinger, D. Fuchs, A. Fuss, A. Garai, V. M. Ghete, S. Gerster, P. Gorla, P. V. Guillaumon, S. Gupta, D. Hauff, M. Ješkovský, J. Jochum, M. Kaznacheeva, A. Kinast, H. Kluck, H. Kraus, A. Langenkämper, M. Mancuso, L. Marini, L. Meyer, V. Mokina, A. Nilima, M. Olmi, T. Ortmann, C. Pagliarone, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Pucci, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, D. Schmiedmayer, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, M. Willers, V. Zema
- Subjects
Physics ,QC1-999 - Abstract
The CRESST experiment observes an unexplained excess of events at low energies. In the current CRESST-III data-taking campaign we are operating detector modules with different designs to narrow down the possible explanations. In this work, we show first observations of the ongoing measurement, focusing on the comparison of time, energy and temperature dependence of the excess in several detectors. These exclude dark matter, radioactive backgrounds and intrinsic sources related to the crystal bulk as a major contribution.
- Published
- 2023
- Full Text
- View/download PDF
32. Exploring coherent elastic neutrino-nucleus scattering of reactor neutrinos with the NUCLEUS experiment
- Author
-
C. Goupy, H. Abele, G. Angloher, A. Bento, L. Canonica, F. Cappella, L. Cardani, N. Casali, R. Cerulli, I. Colantoni, A. Cruciani, G. del Castello, M. del Gallo Roccagiovine, A. Doblhammer, S. Dorer, A. Erhart, M. Friendl, A. Garai, V. M. Ghete, D. Hauff, F. Jeanneau, E. Jericha, M. Kaznacheeva, A. Kinast, H. Kluck, A. Langenkämper, T. Lasserre, D. Lhuillier, M. Mancuso, B. Mauri, A. Mazzolari, E. Mazzucato, H. Neyrial, C. Nones, L. Oberauer, T. Ortmann, L. Pattavina, L. Peters, F. Petricca, W. Potzel, F. Pröbst, F. Pucci, F. Riendl, R. Rogly, M. Romagnoni, J. Rothe, N. Schermer, J. Schieck, S. Schönert, C. Schwertner, L. Scola, G. Soum Sidikov, L. Stodolsky, R. Strauss, M. Tamisari, C. Tomei, M. Vignati, M. Vivier, V. Wagner, A. Wex (The NUCLEUS collaboration)
- Subjects
Physics ,QC1-999 - Abstract
The NUCLEUS experiment aims to perform a high-precision measurement of Coherent Elastic Neutrino-Nucleus Scattering (CEvNS) at the EdF Chooz B nuclear power plant in France. CEvNS is a unique process to study neutrino properties and to search for physics beyond the Standard Model. The study of CEvNS is also important for light Dark-Matter searches. It could be a possible irreducible background for high-sensitivity Dark-Matter experiments. NUCLEUS is an experiment under construction based on ultra-low threshold ($\sim$20 eV$_{nr}$) cryogenic calorimeters, operated at tens-of-mK temperatures.
- Published
- 2023
- Full Text
- View/download PDF
33. Characterisation of low background CaWO$_4$ crystals for CRESST-III
- Author
-
A. Kinast, G. Angloher, S. Banik, G. Benato, A. Bento, A. Bertolini, R. Breier, C. Bucci, J. Burkhart, L. Canonica, A. D'Addabbo, S. Di Lorenzo, L. Einfalt, A. Erb, F. v. Feilitzsch, N. Ferreiro Iachellini, S. Fichtinger, D. Fuchs, A. Fuss, A. Garai, V.M. Ghete, S. Gerster, P. Gorla, P.V. Guillaumon, S. Gupta, D. Hauff, M. Ješkovský, J. Jochum, M. Kaznacheeva, H. Kluck, H. Kraus, A. Langenkämper, M. Mancuso, L. Marini, L. Meyer, V. Mokina, A. Nilima, M. Olmi, T. Ortmann, C. Pagliarone, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Pucci, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, D. Schmiedmayer, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, M. Willers, V. Zema (CRESST Collaboration)
- Subjects
Physics ,QC1-999 - Abstract
The CRESST-III experiment aims at the direct detection of dark matter particles via their elastic scattering off nuclei in a scintillating CaWO$_4$ target crystal. For many years CaWO$_4$ crystals have successfully been produced in-house at Technische Universität München with a focus on high radiopurity. To further improve the CaWO$_4$ crystals, an extensive chemical purification of the raw materials has been performed and the crystal TUM93 was produced from this powder. We present results from an $\alpha$-decay rate analysis performed on 344 days of data collected in the ongoing CRESST-III data-taking campaign. The $\alpha$-decay rate could significantly be reduced.
- Published
- 2023
- Full Text
- View/download PDF
34. NEOTROPICAL ALIEN MAMMALS : a data set of occurrence and abundance of alien mammals in the Neotropics
- Author
-
da Rosa, Clarissa Alves, Ribeiro, Bruno R., Bejarano, Vanesa, Puertas, Fernando Henrique, Bocchiglieri, Adriana, dos Santos Barbosa, Adriana Loeser, Chiarello, Adriano Garcia, Paglia, Adriano Pereira, Pereira, Adriele Aparecida, de Souza Moreira, Adryelle Francisca, de Souza, Agnis Cristiane, Pellegrin, Aiesca, Gatica, Ailin, Medeiro, Akyllan Zoppi, Pereira, Alan Deivid, Braz, Alan Gerhardt, Yanosky, Alberto, Valenzuela, Alejandro Eduardo Jorge, Bertassoni, Alessandra, dos Santos Venturinido Prado, Alessandra, Nava, Alessandra Ferreira Dales, Rocha, Alessandro, Bovo, Alex Augusto Abreu, Bager, Alex, Cravino, Alexandra, dos Santos Pires, Alexandra, Martensen, Alexandre Camargo, Filippini, Alexandre, Percequillo, Alexandre Reis, Vogliotti, Alexandre, Antunes, Alexsander Zamorano, de Oliveira, Aline Cristina Leite, da Silva de Oliveira, Allan Jefferson, Devlin, Allison, de Paula, Almir, Ferreira, Aluane Silva, García-Olaechea, Alvaro, Subalusky, Amanda, Sánchez, Amadeo, de Aquino, Ana Carla Medeiros Morato, Srbek-Araujo, Ana Carolina, Gonçales, Amane Paldês, Araújo, Ana Caroline L., Gozzi, Ana Cecilia, Ochoa, Ana Cecilia, de Oliveira, Ana Cristina Mendes, Lacerda, Ana Cristyna Reis, Francisco, Ana Karina, de Oliveira Paschoal, Ana Maria, Gomes, Ana Paula Nascimento, Potrich, Ana Paula, Olímpio, Ana Priscila Medeiros, Rojas, Ana, Meiga, Ana Yoko Ykeuti, de Almeida Jácomo, Anah Tereza, Calaça, Analice Maria, Feijó, Anderson, Pagoto, Anderson, Miranda, André Borja, Alonso, André Chein, Barreto-Lima, André Felipe, Lanna, Andre, Luza, André Luís, Camilo, André Restel, Tavares, André, Nunes, André Valle, Kindel, Andreas, de Miguel, Andrés, Gatti, Andressa, Nobre, Andrezza Bellotto, da Conceição Campêlo, Anielise, de Albuquerque, Anna Carolina Figueiredo, de la Torre, Antonio, Mangione, Antonio, Pontes, Antonio Rossano Mendes, Fernandes, Arthur Soares, de Almeida Felicio, Artur Luiz, Ferreguetti, Atilla Colombo, Marcili, Arlei, Piratelli, Augusto João, do Nascimento, Ariel Guilherme Santos, dos Santos, Áureo Banhos, Rosa, Beatris Felipe, Cezila, Beatriz Azevedo, de Thoisy, Benoit, Ingberman, Bianca, Köhler, Bianca, Morais, Bianca Cruz, Gómez-Valencia, Bibiana, de Camargo, Bruna Bertagni, Bezerra, Bruna M., Tamasauskas, Bruna, Campos, Bruno A. T. Parahyba, Kubiak, Bruno Busnello, Saranholi, Bruno Henrique, Nakagawa, Bruno K., Leles, Bruno Pereira, Lim, Burton K., Mendes, Calebe Pereira, Islas, Camila Alvez, Aoki, Camila, Devids, Camila Cantagallo, Figueiredo, Camila, de Abreu, Camila Matias Goes, Oliveira, Camila Raquel Silva, Cassano, Camila Righetto, Lugarini, Camile, Caputo, Carin, Gestich, Carla Cristina, Tedesco, Carla Denise, de Vera y Conde, Carla Fabiane, Hegel, Carla Grasiele Zanin, Kasper, Carlos Benhur, De Angelo, Carlos, Grelle, Carlos E. V., Fragoso, Carlos Eduardo, Esbérard, Carlos Eduardo Lustosa, Rocha, Carlos Frederico Duarte, Verona, Carlos Eduardo, Salvador, Carlos Henrique, Vieira, Carlos Leonardo, Abrahão, Carlos Roberto, Brocardo, Carlos Rodrigo, Fieker, Carolline Zatta, Braga, Caryne, Lalinde, Catalina Sánchez, Bueno, Cecília, Ikuta, Cássia Yumi, Luna, Cecília Licarião Barreto, Cestari, Cesar, Del Vechio Koike, Christine, Knogge, Christoph, Anderson, Christopher Brian, Hurtado, Cindy M., de Oliveira, Cintia Ferreira Antunes, Tellaeche, Cintia, Cesário, Clarice Silva, Costa, Claudia Guimarães, Kanda, Claudia Zukeran, Costa, Sebastián Andrés, Seixas, Cristiana Simão, Trinca, Cristiano Trapé, López-Fuerte, Cristina F., da Cunha, Cristina Jaques, Ribas, Cynthia Doutel, Santos, Cyntia Cavalcante, Buscariol, Daiane, Carreira, Daiane, do Nascimento, Daiane Chaves, Carvalho, Danianderson Rodrigues, da Silva Ferraz, Daniel, Galiano, Daniel, Homem, Daniel Henrique, Jesús-Espinosa, Daniel, Bôlla, Daniela A. S., Moreno, Daniele Janina, de Oliveira Moreira, Danielle, Ramos, Danielle Leal, de Amorim, Danilo Angelucci, Barros-Battesti, Darci Moraes, Lopez, David Echeverri, Tavares, Davi Castro, Post, David M., Couto, Dayvid Rodrigues, Patrocínio, Dennis Nogarolli, Carvalho, Diana Letícia Kruger Pacheco, Silva, Diego Afonso, Córdoba, Diego, Queirolo, Diego, Varela, Diego, de Oliveira, Dilmar Alberto Goncalves, Casanova, Diogo Cavenague, de Matos Dias, Douglas, da Silva, Douglas Machado, Barbier, Eder, Rivadeneira, Edgar Federico, Alexandrino, Eduardo, Carrano, Eduardo, Santos, Eduardo Marques, Venticinque, Eduardo Martins, Hernández-Pérez, Edwin, da Fonseca Casazza, Egberto, Anderson, Elizabeth P., da Costa Fraga, Elmary, de Lima, Elson Fernandes, D’Bastiani, Elvira, Vieira, Emerson Monteiro, Guijosa-Guadarrama, Emiliano, González, Enrique M., Maggiorini, Erica Vanessa, de Aguiar, Erick Francisco Silva, Martínez-Nambo, Erik Daniel, Castro, Érika Paula, de la Peña-Cuéllar, Erika, Pedó, Ezequiel, de Melo, Fabiana Cristina S. Alves, Rocha, Fabiana Lopes, Fonseca, Fabiana Luques, Girardi, Fabiane, de Melo, Fabiano Rodrigues, de Oliveira Roque, Fábio, Ferreira, Fabíola Keesen, Peters, Felipe Bortolotto, Fantacini, Felipe Moreli, Pedrosa, Felipe, da Silva, Felipe Pessoa, Vélez-García, Felipe, Abra, Fernanda D., de Azevedo, Fernanda Cavalcanti, da Silva, Fernanda Guedes, Neri, Fernanda Maria, Teixeira, Fernanda Zimmermann, dos Santos Fernandez, Fernando Antonio, Carvalho, Fernando, Passos, Fernandode Camargo, de Castro Jacinavicius, Fernando, Ferreira, Fernando, de Pinho, Fernando Ferreira, Gonçalves, Fernando, Martins, Fernando Ibanez, Lima, Fernando, Contreras-Moreno, Fernando M., Ribeiro, Fernando Silvério, Tortato, Fernando, Patel, Filipe M., Caruso, Flavia, Tirelli, Flávia Pereira, Rodrigues, Flávio Henrique Guimarães, Ubaid, Flávio Kulaif, Palmeira, Francesca Belem Lopes, Neto, Francisco Grotta, Gabriel, Francisco Homem, de Souza, Franco Leandro, da Veiga da Costa, Francys E., de Aguiar, Gabriel Lima, Lemos, Frederico Gemesio, Magezi, Gabriel S., Di Panigai, Gabriel Ferreira Vianna, Hofmann, Gabriel Selbach, Heliodoro, Gabriela, Graviola, Gabriela Rosa, Beca, Gabrielle, de Andrade, Gabrielle Ribeiro, Romero, Germán Jiménez, Duarte, Gabriela Teixeira, Melo, Geruza Leal, Dierings, Geverson Luiz, Sabino-Santos, Gilberto, de Oliveira, Geovana Linhares, Santana, Gindomar Gomes, Ciocheti, Giordano, Zanirato, Gisele Lamberti, Alves, Giselle Bastos, Batista, Graziele Oliveira, Behling, Greici Maia, Ferreira, Guilherme Braga, da Rocha, Guilherme Casoni, Lessa, Gisele, Mourão, Guilherme, Maras, Gustavo A., da Costa Toledo, Gustavo Alves, Gonsioroski, Gustavo, Canale, Gustavo R., Schuchmann, Karl-Ludwig, Sebastião, Harley, do Prado, Helena Alves, de Godoy Bergallo, Helena, Secco, Helio Kinast Cruz, Roig, Henrique Llacer, Rajão, Henrique, Carlos, Henrique Santiago Alberto, de Oliveira B. Duarte, Herbert, Ermenegildo, Hiago, de Jesus Pena, Hilda Fátima, Júnior, Hilton Entringer, Neto, Hipólito Ferreira Paulino, de Macedo Lemos, Hudson, del Castillo, Hugo, Fernandes-Ferreira, Hugo, Banquero, Hugo Ignacio Coitiño, Roesler, Ignacio, Ribeiro, Igor Kintopp, Coelho, Igor Pfeifer, Lima, Ingrid M. S., Bechara, Isabel Muniz, Lermen, Isabel Salgueiro, Méndez, Isac Mella, Schuck, Gabriela, Esperandio, Isadora Beraldi, de Oliveria Silva, Ita, Mourthe, Italo, Oliveira, Igor, Bernardi, Itiberê Piaia, Miller, Jacqueline R., Marinho-Filho, Jader, Zocche, Jairo José, Russell, James Charles, Seibert, Jardel Brandão, Hinojosa, Javier, Vitule, Jean R. S., Thompson, Jeffrey J., Silva, Jean Carlos Ramos, Gouvea, Jéssica Abonízio, Santos, Jean Pierre, de Faria Falcão, Jéssica Caroline, Castro-Prieto, Jessica, Ferreira, Jéssica Paloma, Pincheira-Ulbrich, Jimmy, Nodari, Joana Zorzal, Gebin, João Carlos Zecchini, Giovanelli, João Gabriel Ribeiro, Miranda, João M. D., Souza-Alves, João Pedro, de Almeida Marins, João Rafael Gomes, Costa, Jociel Ferreira, Sponchiado, Jonas, de Souza, Jonathas Linds, Gallo, Jorge Alberto, Cherem, Jorge José, Cordeiro, José Luís Passos, Duarte, José Maurício Barbanti, Dantas, José Oliveira, de Matos, José Roberto, Pires, José Salatiel Rodrigues, Lanfranco, Juan Andrés Martínez, de la Cruz Godoy, Juan Camilo, Rudolf, Juan Carlos, Parrish, Juan Felipe Reátiga, Tellarini, Juan Francisco, Peña-Mondragón, Juan L., Arrabal, Juan Pablo, Reppucci, Juan, Ruiz-Esparza, Juan, Beduschi, Julia, de Faria Oshima, Júlia Emi, Ribeiro, Juliana Fernandes, de Almeida Rocha, Juliana Monteiro, Neto, José Soares Ferreira, dos Santos, Juliana Silveira, Pereira-Ribeiro, Juliane, Zanoni, Juliani Bruna, Bogoni, Juliano André, Ferreira, Juliana Rodrigues, Bicca-Marques, Júlio César, Pacheco, Julio Javier Chacón, de Oliveira Scarascia, Pietro, Guidoni-Martins, Karlo Gregório, Burs, Kathrin, de Barros Ferraz, Katia Maria Paschoaletto Micchi, Pisciotta, Kátia Regina, Von Kossel de Andrade Silva, Katyucha, Juarez, Keila MacFadem, de 1a Cruz-Félix, Keynes, de Morais, Kimberly Danielle Rodrigues, Candelária, Lana Pavão, Fornitano, Larissa, Bailey, Larissa Lynn, Gonçalves, Larissa Oliveira, Fasola, Laura, León, Laura Johanna Nova, de Andrade, Layla Reis, de Oliveira Marques, Leandro, Macedo, Leandro, Moreira, Leandro Santana, Silveira, Leandro, de Carvalho Oliveira, Leonardo, da Silva, Leonardo Henrique, Jerusalinsky, Leandro, La Serra, Leonardo, Costa, Leonardo Marques, Sartorello, Leonardo Rodrigues, Munhoes, Leticia Prado, Oliveira-Silva, Liany Regina B., de Pina, Ligia Ferracine, Bonjorne, Lilian, Rampim, Lilian Elaine, Sales, Lilian P., da Silva, Lucas Gonçalves, Quintilham, Lucas Lacerda Toth, Perillo, Lucas Neves, Rodríguez-Planes, Lucía Inés, Martín, Lucía, Araújo, Luciana Souza, Tiepolo, Liliani Marilia, Silva, Luciana Zago, Loaiza, Lina Marcela García, de Alagão Querido, Luciano Carramaschi, da Silva, Luciano Ferreira, La Sala, Luciano Francisco, Bopp, Luciano Tessare, Hufnagel, Ludmila, de Oliveira, Luiz Flamarion Barbosa, Oliveira-Santos, Luiz Gustavo Rodrigues, Lyra, Luiz Henrique, Guimarães, Luiza Neves, Segura, Luz Fernanda Jimenez, de Sousa, Luziene Conceição, Möcklinghoff, Lydia, Guichón, M. Laura, de la Maza, Javier, Barrios-Garcia, M. Noelia, Talamoni, Sônia A., Severo, Magnus Machado, Martins, Maísa Ziviani Alves, Oliveira, Marcela Alvares, Moraes, Marcela Figuerêdo Duarte, Lima, Marcela Guimarães Moreira, Pinheiro, Marcell Soares, do Carmo Pônzio, Marcella, Guerreiro, Marcello, Cervini, Marcelo, da Silva, Marcelo, Oliveira, Marcelo Juliano Rabelo, Magioli, Marcelo, Passamani, Marcelo, de Almeida, Marcelo Silva, Amaku, Marcos, de Oliveira, Márcio Leite, Tortato, Marcos Adriano, Melo, Marcos Antônio, Coutinho, Marcos E., Santos, Marcos Pérsio Dantas, Vieira, Marcus V., Andrade, Maria Augusta, Barros, Maria Claudene, do Rosario, Maria Cristina Ferreira, dos Santos Domit, Maria Dolores Alves, de Avelar Fernandes, Maria Emília, Iezzi, María Eugenia, do Nascimento, Maria Histele Sousa, Andrade-Núñez, María José, Lorini, Maria Lucia, de Castro Morini, Maria Santina, Nagy-Reis, Mariana B., Landis, Mariana Bueno, Vale, Mariana Moncassim, Xavier, Mariana Sampaio, Kaizer, Mariane C., Baptiste, Maria Piedad, Bergel, Mariano Maudet, Borgnia, Mariela, Barros, Marília A. S., da Silva, Marina Lima, Favarini, Marina Ochoa, Munerato, Marina Sales, Zaluar, Marina Trancoso, Winter, Marina, da Silva, Marina Xavier, Zanin, Marina, Marques, Marinêz Isaac, Haberfeld, Mario Burke, Di Bitetti, Mario S., Galliez, Maron, Alvarez, Martin R., Malerba, Martina, Rivero, Marina, Dias, Mateus Melo, de Oliveira, Mateus Yan, dos Reis, Matheus Gonçalves, Corrêa, Matheus Rocha Jorge, Graipel, Maurício Eduardo, Godoi, Mauricio N., Núñez-Regueiro, Maurício M., Moura, Mauricio Osvaldo, Orsi, Mário Luís, da Silva, Marco Aurélio Galvão, Lopez, Mauro Sanvicente, Benedetti, Maximiliano Augusto, Beltrão, Mayara Guimarães, Camino, Micaela, Faria, Michel Barros, Miretzki, Michel, Luiz, Micheli Ribeiro, Perine, Michell, Monteiro, Miguel Coutinho Moretta, Alves-Eigenheer, Milene, Perilli, Miriam Lucia Lages, da Silva, Mônica Andrade, Marini, Miguel Ângelo, Pereira, Monicque Silva, de Freitas Junior, Mozart Caetano, Cossa, Natalia, Denkiewicz, Natalia Mariana, Tôrres, Natália Mundim, Olifiers, Natalie, de Albuquerque, Natasha Moraes, Canassa, Nathália Fernandes, Detogne, Nathália, Filho, Newton Gurgel, Seoane, Nicolás Fernando, da Rosa Oliveira, Nicole, Megale, Nicoli, Pasqualotto, Nielson, Cáceres, Nilton Carlos, Peroni, Nivaldo, Zanella, Noeli, Pays, Olivier, Arimoro, Omolabake Alhambra Silva, Acevedo-Charry, Orlando, de Almeida Curi, Nelson Henrique, Pinha, Patricia Ribeiro Salgado, Perovic, Pablo, Gonçalves, Pablo Rodrigues, Santos, Paloma Marques, de Goés Brennand, Pamella Gusmão, Rogeri, Patrícia Kerches, Ribeiro, Patrícia Rosas, da Rocha, Patrício Adriano, de Lázari, Patrick Ricardo, Pedreira, Paula Anabel, Pinheiro, Paula Fabiana, Lira, Paula Koeler, Ferreira, Paula Modenesi, Martin, Paula Sanches, de Tarso Zuquim Antas, Paulo, Marinho, Paulo Henrique, Ruffino, Paulo Henrique Peira, Camargo, Paulo Henrique S. A., Filho, Paulo Landgref, Mangini, Paulo Rogério, Farias, Patrick, Cordeiro-Estrela, Pedro, de Faria Peres, Pedro Henrique, Galetti, Pedro Manoel, Ramírez-Bautista, Pedro, de Almeida Maués, Paula Cristina Rodrigues, Renaud, Pierre-Cyril, Sartorello, Ricardo, de Barros, Pollyanna Alves, Lombardi, Pryscilla Moura, Bessa, Rafael, Arroyo-Gerala, Paulina, de Souza, Rafael Cerqueira Castro, Zenni, Rafael D., Peredo, Rafael Flores, Hoogesteijn, Rafael, Loyola, Rafael, Alves, Rafael Souza Cruz, de Paula Rodarte, Raisa Reis, Silva, Ramon Lima, de Oliveira, Ramonna, Beltrão-Mendes, Raone, de Macêdo Alencar, Raony, da Silva, Raquel Costa, Pedroso, Rayssa, Sampaio, Rebeca Ferreira, Ribeiro, Renan Lieto Alves, Pardini, Renata, Bonikowski, Renata Twardowsky Ramalho, Pagotto, Renata Valls, Dias, Ricardo Augusto, Bassini-Silva, Ricardo, Arrais, Ricardo Corassa, Sampaio, Ricardo, de Cassia Bianchi, Rita, Paolino, Roberta Montanheiro, Fusco-Costa, Roberto, Trovati, Roberto Guilherme, Hack, Robson Odeli Espíndola, de Arruda Mauro, Rodiney, de Almeida Nobre, Rodrigo, Gessulli, Rodrigo Delmonte, Pérez, Rodrigo León, Massara, Rodrigo Lima, da Silva, Rodrigo Medina Fróes, de Paula, Rogério Cunha, da Cunha, Rogério Grassetto Teixeira, Costa, Rômulo Theodoro, Marques, Rosane Vera, Morato, Ronaldo Gonçalves, Bovendorp, Ricardo S., da Paixão Dornas, Rubem Augusto, Andrade, Rubia Santana, Siciliano, Salvatore, Guaragni, Samara Arsego, Rolim, Samir Gonçalves, Astete, Samuel, Cavalcanti, Sandra, Hartz, Sandra Maria, Carvalho, Santiago, Cortez, Sara, de Sousa, Saulo Meneses Silvestre, Ballari, Sebastián A., Lima, Saulo Ramos, Cirignoli, Sebastián, García-R, Sebastian, Bazilio, Sérgio, Torres, Sergio Solari, Franco, Silvana Back, Martins, Simone Rebouças, de Bustos, Soledad, Age, Stefani Gabrieli, Ferrari, Stephen Francis, Francisco, Talitha Mayumi, Micheletti, Tatiane, da Silva Godim, Tayanna Medonça, Luiz, Thais Guimaraes, de Freitas, Thales Renato Ochotorena, Rodrigues, Thiago Ferreira, Piovezan, Ubiratan, Barcos, Umberto Cotrim, Onofrio, Valeria Castilho, Martin-Albarracin, Valeria L., Towns, Valeria, Araújo, Valquíria Cabral, Kanaan, Vanessa, Daga, Vanessa Salete, Boere, Vanner, de Araujo, Verônica Parente Gomes, Benitez, Verónica Victoria, Leandro-Silva, Victor, Geraldi, Vilma Clarice, Alberici, Vinicius, Bastazini, Vinícius Augusto Galvão, de Oliveira Gasparotto, Vinícius Peron, Orsini, Vinícius Santana, da Silva, Virgínia Santiago, Bonzi, Viviana Rojas, Pereira, Vinicius José Alves, Layme, Viviane Maria Guedes, da Silva, Victor Hugo Duarte, Tomas, Walfrido Moraes, De Almeida Moreira, Thamy, Martins, Waldney Pereira, de Moraes Pires, Walna Micaelle, Hannibal, Wellington, Dáttilo, Wesley, Mottin, Viviane, Endo, Whaldener, Bercê, William, Carvalho, William Douglas, Magnusson, William, Akkawi, Paula, Di Blanco, Yamil, Amaral, Paulo Roberto, Ramos, Yan Gabriel Celli, Rodríguez-Calderón, Yenifer G., Mendes, Yuri Raia, Ribeiro, Yuri Geraldo Gomes, Campos, Zilca, Galetti, Mauro, and Ribeiro, Milton Cezar
- Published
- 2020
35. Optic nerve cavitations in glaucoma suspect and glaucoma patients
- Author
-
Bennett Y. Hong, Brad Fortune, Robert M. Kinast, Claude F. Burgoyne, Jack P. Rees, and Steven L. Mansberger
- Subjects
Optic nerve cavitations ,Intrachoroidal cavitations ,Lamina cribosa ,Glaucoma ,Imaging ,Optical coherence tomography ,Ophthalmology ,RE1-994 - Abstract
Purpose: Glaucoma is associated with structural changes of the optic nerve head such as deformation, lamina cribosa defects, prelaminar schisis, and peripapillary retinal schisis. We describe optic nerve cavitations that were detected by routine spectral domain optical coherence tomography (OCT). Observations: OCT imaging showed cavitations in 5 eyes of 4 patients with an initial diagnosis of glaucoma or glaucoma suspect. The cavitations were seen as hyporeflective spaces that are sharply delineated from surrounding tissue. They were centered inferonasally, anterior to the lamina cribosa, and at least partially within the Bruch's membrane opening (BMO). They extended from 3 to 6 clock hours. Conclusion: AND IMPORTANCE: We describe a new OCT finding in patients with a diagnosis of glaucoma and glaucoma suspect. While previous reports describe cavitations in the choroid in patients with pathological myopia, our patients had minimal refractive error and the cavitations were located within the optic nerve. We will examine these patients over time to determine the impact of this finding on longitudinal changes in structure and function.
- Published
- 2022
- Full Text
- View/download PDF
36. Energy deposition in coolant of PWR under normal operation and accident conditions
- Author
-
Kinast, Shai and Tomatis, Daniele
- Published
- 2021
- Full Text
- View/download PDF
37. Novel Eye Drop Delivery Aid Improves Outcomes and Satisfaction
- Author
-
Sanchez, Facundo G., Mansberger, Steven L., Kung, Yungtai, Gardiner, Stuart K., Burgoyne, Claude F., Cunningham, Emmett T., Jr., Rees, Jack P., Jones, Emily P., and Kinast, Robert M.
- Published
- 2021
- Full Text
- View/download PDF
38. Robust hepatitis E virus infection and transcriptional response in human hepatocytes
- Author
-
Todt, Daniel, Friesland, Martina, Moeller, Nora, Praditya, Dimas, Kinast, Volker, Brüggemann, Yannick, Knegendorf, Leonard, Burkard, Thomas, Steinmann, Joerg, Burm, Rani, Verhoye, Lieven, Wahid, Avista, Meister, Toni Luise, Engelmann, Michael, Pfankuche, Vanessa M., Puff, Christina, Vondran, Florian W. R., Baumgärtner, Wolfgang, Meuleman, Philip, Behrendt, Patrick, and Steinmann, Eike
- Published
- 2020
39. A realistic transfer method reveals low risk of SARS-CoV-2 transmission via contaminated euro coins and banknotes
- Author
-
Todt, Daniel, Meister, Toni Luise, Tamele, Barbora, Howes, John, Paulmann, Dajana, Becker, Britta, Brill, Florian H., Wind, Mark, Schijven, Jack, Heinen, Natalie, Kinast, Volker, Mhlekude, Baxolele, Goffinet, Christine, Krawczyk, Adalbert, Steinmann, Jörg, Pfaender, Stephanie, Brüggemann, Yannick, and Steinmann, Eike
- Published
- 2021
- Full Text
- View/download PDF
40. Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid: experimental studies in thromboelastometry
- Author
-
Tobias Koller, Nadia Kinast, Andres Guilarte Castellanos, Sergio Perez Garcia, Pilar Paniagua Iglesias, Xavi León Vintro, Jose Mateo Arranz, Noelia Vilalta Seto, Ma. Victòria Moral García, Ana Belén Moreno-Castaño, Jose Aznar-Salatti, Gines Escolar Albaladejo, and Maribel Diaz-Ricart
- Subjects
Massive bleeding ,Blood transfusion ,Fibrinogen ,Factor XIII ,Prothrombin complex concentrate ,Fluid therapy ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background Colloid fluids supplemented with adequate combinations of coagulation factor concentrates with the capability to restore coagulation could be a desirable future treatment component in massive transfusion. Methods Starting from a coagulation factor and blood cell-free albumin solution we added Prothrombin Complex Concentrate, Fibrinogen Concentrate and Factor XIII in different combinations and concentrations to analyze their properties to restore thromboelastometry parameters without the use of plasma. Further analysis under the presence of platelets was performed for comparability to whole blood conditions. Results Albumin solutions enriched with Fibrinogen Concentrate, Factor XIII and Prothrombin Complex Concentrate at optimized concentrations show restoring coagulation potential. Prothrombin Complex Concentrate showed sufficient thrombin formation for inducing fibrinogen polymerization. The combination of Prothrombin Complex Concentrate and Fibrinogen Concentrate led to the formation of a stable in vitro fibrin clot. Fibrinogen and Factor XIII showed excellent capacity to improve fibrin clot firmness expressed as Amplitude at 10 min and Maximal Clot Firmness. Fibrinogen alone, or in combination with Factor XIII, was able to restore normal Amplitude at 10 min and Maximal Clot Firmness values. In the presence of platelets, the thromboelastometry surrogate parameter for thrombin generation (Clotting Time) improves and normalizes when compared to whole blood. Conclusions Combinations of coagulation factor concentrates suspended in albumin solutions can restore thromboelastometry parameters in the absence of plasma. This kind of artificial colloid fluids with coagulation-restoring characteristics might offer new treatment alternatives for massive transfusion. Trial registration Study registered at the institutional ethic committee “Institut de Recerca, Hospital Santa Creu i Sant Pau, with protocol number IIBSP-CFC-2013-165.
- Published
- 2021
- Full Text
- View/download PDF
41. Biased random-key genetic algorithm for cobot assignment in an assembly/disassembly job shop scheduling problem
- Author
-
Kinast, Alexander, Doerner, Karl F., and Rinderle-Ma, Stefanie
- Published
- 2021
- Full Text
- View/download PDF
42. A cone beam CT based 3D-assessment of bony forefoot geometry after modified Lapidus arthrodesis
- Author
-
Scheele, Christian B., Christel, Simon T., Fröhlich, Imke, Mehlhorn, Alexander, Walther, Markus, Hörterer, Hubert, Harrasser, Norbert, and Kinast, Christian
- Published
- 2020
- Full Text
- View/download PDF
43. Parametric Sensitivity Analysis of Stability Margins of Holos-Quad Microreactor.
- Author
-
Kinast, Shai, Price, Dean, Filippone, Claudio, and Kochunas, Brendan
- Abstract
AbstractAn analysis of the stability margins of the innovative Holos-Quad microreactor design is presented. This high-temeprature gas-cooled reactor (HTGR) system is designed to operate fully autonomously with passive safety mechanisms. Therefore, the inherent stability of the reactor is of great importance. Using a point-reactor model, which couples point kinetics to thermal-hydraulic heat balance equations and includes reactivity feedback effects of the fuel and moderator temperatures, the closed-loop transfer function of the reactor is derived. Applying the approach of linear systems and control theory, both the gain and phase margins of the Holos-Quad design are obtained. The analysis demonstrates that the design is stable, with an infinite gain margin and a finite phase margin.A parametric uncertainty quantification study is also performed using a total Monte Carlo approach. The stability of the reactor for different power levels, such as during reactor startup or load-following transients, is also explored. Finally, two sensitivity analysis methods are applied, namely, multiple regression (deriving standardized regression coefficients) and variance-based sensitivity analysis (known as the Sobol method), to study the contribution of each of the parameters to the stability margins’ uncertainty. This analysis improves our understanding of the role of each of the parameters in the stability of the reactor. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
44. Challenges and Lessons Learned in Mapping HL7 v2 Data to openEHR: Insights from UKSH Medical Data Integration Center.
- Author
-
ANYWAR, Michael, MACEDO, Mário, PAZMINO, Santiago, BRONSCH, Tobias, KINAST, Benjamin, KOCK-SCHOPPENHAUER, Ann-Kristin, and SCHREIWEIS, Björn
- Abstract
This paper explores the challenges and lessons learned during the mapping of HL7 v2 messages structured using custom schema to openEHR for the Medical Data Integration Center (MeDIC) of the University Hospital, Schleswig- Holstein (UKSH). Missing timestamps in observations, missing units of measurement, inconsistencies in decimal separators and unexpected datatypes were identified as critical inconsistencies in this process. These anomalies highlight the difficulty of automating the transformation of HL7 v2 data to any standard, particularly openEHR, using off-the-shelf tools. Addressing these anomalies is crucial for enhancing data interoperability, supporting evidence-based research, and optimizing clinical decision-making. Implementing proper data quality measures and governance will unlock the potential of integrated clinical data, empowering clinicians and researchers and fostering a robust healthcare ecosystem. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
45. Implementation of an Atrioventricular Valve Intervention Registry: Comparative Study of REDCap vs. CDR-Based openEHR Registry.
- Author
-
KINAST, Benjamin, ROHDE, Henrik, ANYWAR, Michael, Tobias, BRONSCH, VORAN, Jakob, KREIDL, Felix, FRANK, Derk, and SCHREIWEIS, Björn
- Abstract
This comparative study examines the transition from isolated registries to a consolidated data-centric approach at University Hospital Schleswig-Holstein, focusing on migrating the Atrioventricular Valve Intervention Registry (AVIR) from REDCap to a Medical Data Integration Center based openEHR registry. Through qualitative analysis, we identify key disparities and strategic decisions guiding this transition. While REDCap has historical utility, its limitations in automated data integration and traceability highlight the advantages of a data-centric approach, which include streamlined data (integration) management at a singlepoint-of-truth based on e.g., centralized consent management. Our findings lay the groundwork for the AVIR project and a proof-of-concept data-centric registry, reflecting a broader industry trend towards data-centric healthcare initiatives. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
46. Probing spin-dependent dark matter interactions with 6Li: CRESST Collaboration
- Author
-
Angloher, G., Benato, G., Bento, A., Bertoldo, E., Bertolini, A., Breier, R., Bucci, C., Canonica, L., D’Addabbo, A., Di Lorenzo, S., Einfalt, L., Erb, A., Feilitzsch, F. v., Ferreiro Iachellini, N., Fichtinger, S., Fuchs, D., Fuss, A., Garai, A., Ghete, V. M., Gorla, P., Gupta, S., Hauff, D., Ješkovský, M., Jochum, J., Kaznacheeva, M., Kinast, A., Kluck, H., Kraus, H., Langenkämper, A., Mancuso, M., Marini, L., Mokina, V., Nilima, A., Olmi, M., Ortmann, T., Pagliarone, C., Palušová, V., Pattavina, L., Petricca, F., Potzel, W., Povinec, P., Pröbst, F., Pucci, F., Reindl , F., Rothe, J., Schäffner, K., Schieck, J., Schmiedmayer, D., Schönert, S., Schwertner, C., Stahlberg, M., Stodolsky, L., Strandhagen, C., Strauss, R., Usherov, I., Wagner, F., Willers, M., and Zema, V.
- Published
- 2022
- Full Text
- View/download PDF
47. Neutron Diffraction Investigation of the DyFe11Ti Magnetic Structure and Its Spin Reorientations
- Author
-
Isnard, Olivier and Kinast, Eder J.
- Published
- 2020
- Full Text
- View/download PDF
48. Intraocular Pressure and Medication Burden With Cataract Surgery Alone, or Cataract Surgery Combined With Trabecular Bypass or Goniotomy
- Author
-
McNiel, Christopher L., Sanchez, Facundo G., Rees, Jack P., Gardiner, Stuart K., Young, Jonathan W., Kinast, Robert M., Young, Amber, Jones, Emily P., and Mansberger, Steven L.
- Published
- 2022
- Full Text
- View/download PDF
49. Cryogenic characterization of a $$\hbox {LiAlO}_{2}$$ LiAlO 2 crystal and new results on spin-dependent dark matter interactions with ordinary matter
- Author
-
A. H. Abdelhameed, G. Angloher, P. Bauer, A. Bento, E. Bertoldo, R. Breier, C. Bucci, L. Canonica, A. D’Addabbo, S. Di Lorenzo, A. Erb, F. V. Feilitzsch, N. Ferreiro Iachellini, S. Fichtinger, D. Fuchs, A. Fuss, V. M. Ghete, A. Garai, P. Gorla, D. Hauff, M. Ješkovský, J. Jochum, J. Kaizer, M. Kaznacheeva, A. Kinast, H. Kluck, H. Kraus, A. Langenkämper, M. Mancuso, V. Mokina, E. Mondragon, M. Olmi, T. Ortmann, C. Pagliarone, V. Palušová, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, V. Schipperges, D. Schmiedmayer, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, M. Willers, V. Zema, J. Zeman, M. Brützam, and S. Ganschow
- Subjects
Dark matter ,Cryogenics ,Spin-dependent ,Lithium ,Neutrons ,Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract In this work, a first cryogenic characterization of a scintillating $$\hbox {LiAlO}_{2}$$ LiAlO 2 single crystal is presented. The results achieved show that this material holds great potential as a target for direct dark matter search experiments. Three different detector modules obtained from one crystal grown at the Leibniz-Institut für Kristallzüchtung (IKZ) have been tested to study different properties at cryogenic temperatures. Firstly, two 2.8 g twin crystals were used to build different detector modules which were operated in an above-ground laboratory at the Max Planck Institute for Physics (MPP) in Munich, Germany. The first detector module was used to study the scintillation properties of $$\hbox {LiAlO}_{2}$$ LiAlO 2 at cryogenic temperatures. The second achieved an energy threshold of ( $$213.02\pm 1.48$$ 213.02 ± 1.48 ) eV which allows setting a competitive limit on the spin-dependent dark matter particle-proton scattering cross section for dark matter particle masses between $$350\,\hbox {MeV/c}^{2}$$ 350 MeV/c 2 and $$1.50\,\hbox {GeV/c}^{2}$$ 1.50 GeV/c 2 . Secondly, a detector module with a 373 g $$\hbox {LiAlO}_{2}$$ LiAlO 2 crystal as the main absorber was tested in an underground facility at the Laboratori Nazionali del Gran Sasso (LNGS): from this measurement it was possible to determine the radiopurity of the crystal and study the feasibility of using this material as a neutron flux monitor for low-background experiments.
- Published
- 2020
- Full Text
- View/download PDF
50. Neutron Diffraction Investigation of the DyFe11Ti Magnetic Structure and Its Spin Reorientations
- Author
-
Olivier Isnard and Eder J. Kinast
- Subjects
Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
In this article, we report on the magnetic structure of DyFe11Ti and its thermal evolution as probed by neutron powder diffraction. A thermodiffraction technique was used to follow the temperature dependence of the magnetic moments, as well as their orientation. The Dy and Fe moments were coupled to each other in an antiparallel manner to form a ferrimagnet, where the easy magnetization direction at 2 K was the [110] axis in the basal (a, b) plane. This magnetic structure underwent two successive spin reorientation phenomena with increasing temperature. A large Dy magnetic moment of 9.7 Bohr magneton (μB) was obtained at low temperatures, and the magnitude decreased rapidly to 7.5μB at 200 K. The largest Fe magnetic moment was observed on the Fe 8i position. A ThMn12-type crystal structure was preserved in the studied temperature range, despite the large changes of the magnetic structure. A sharp tilt was observed at the first-order spin reorientation, TSR1; the angle between the easy magnetization axis and the crystal c axis was reduced from 90° at 2 K to about 20° at 200 K (where c is the easy axis above 200 K); and the Dy and Fe magnetic moments maintained an antiparallel coupling. Keywords: Neutron diffraction, Magnetic phase diagram, Crystal structure
- Published
- 2020
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.