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Your search keyword '"Kenny, Eimear E."' showing total 156 results

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156 results on '"Kenny, Eimear E."'

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1. An Ethical Framework for Research Using Genetic Ancestry

2. Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate

4. Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes

5. Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

6. Assessing efficiency of fine-mapping obesity-associated variants through leveraging ancestry architecture and functional annotation using PAGE and UKBB cohorts

7. Evaluating parental personal utility of pediatric genetic and genomic testing in a diverse, multilingual population

9. Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

10. Getting Genetic Ancestry Right for Science and Society

11. Managing differential performance of polygenic risk scores across groups: Real-world experience of the eMERGE Network

12. MUSSEL: Enhanced Bayesian polygenic risk prediction leveraging information across multiple ancestry groups

13. Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease

14. Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome

15. The TeleKidSeq pilot study: incorporating telehealth into clinical care of children from diverse backgrounds undergoing whole genome sequencing

16. A draft human pangenome reference

17. Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

18. Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals

19. Physician services and costs after disclosure of diagnostic sequencing results in the NYCKidSeq program

20. The NYCKidSeq randomized controlled trial: Impact of GUÍA digitally enhanced genetic results disclosure in diverse families

21. Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics

22. Molecular diagnostic yield of genome sequencing versus targeted gene panel testing in racially and ethnically diverse pediatric patients

24. Poison exon annotations improve the yield of clinically relevant variants in genomic diagnostic testing

25. Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

26. Returning integrated genomic risk and clinical recommendations: The eMERGE study

27. Genome-wide polygenic score to predict chronic kidney disease across ancestries

28. Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

29. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

30. Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations

31. Rare coding variants in RCN3 are associated with blood pressure

32. Beyond the Human Genome Project: The Age of Complete Human Genome Sequences and Pangenome References.

33. GenomeDiver: a platform for phenotype-guided medical genomic diagnosis

34. Neptune: an environment for the delivery of genomic medicine

36. GUÍA: a digital platform to facilitate result disclosure in genetic counseling

38. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

39. Implementing genomic screening in diverse populations

40. An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease

42. A positively selected FBN1 missense variant reduces height in Peruvian individuals

43. Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network

44. Genetic analyses of diverse populations improves discovery for complex traits

45. Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations

47. The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis

48. A multi-stage genome-wide association study of uterine fibroids in African Americans

49. Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

50. Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations

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