41 results on '"Horne, Christopher R."'
Search Results
2. CaMKK2 as an emerging treatment target for bipolar disorder
3. Large-scale genomic investigation of pediatric cholestasis reveals a novel hepatorenal ciliopathy caused by PSKH1 mutations
4. Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization
5. A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
6. TRAPs: the ‘elevator-with-an-operator’ mechanism
7. Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL
8. Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL
9. Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation.
10. N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
11. Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling
12. A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells
13. Multi-wavelength analytical ultracentrifugation as a tool to characterise protein–DNA interactions in solution
14. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
15. Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
16. Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix
17. Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker
18. Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
19. “Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes
20. The web of death: the expanding complexity of necroptotic signaling
21. Nanobodies identify an activated state of the TRIB2 pseudokinase
22. A common humanMLKLpolymorphism confers resistance to negative regulation by phosphorylation
23. Giving Children Space: A Phenomenological Exploration of Student Experiences in Space Science Inquiry
24. Nanobodies identify an activated state of the TRIB2 pseudokinase
25. Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation
26. The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
27. SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization
28. Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL
29. For Whom the Bell Tolls: The Structure of the Dead Kinase, IRAK3
30. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
31. Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2
32. A toolbox for imaging RIPK1, RIPK3 and MLKL in mouse and human cells
33. Structure–Function Studies of the Antibiotic Target l,l-Diaminopimelate Aminotransferase from Verrucomicrobium spinosum Reveal an Unusual Oligomeric Structure
34. On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism
35. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
36. Cover Image, Volume 88, Issue 5
37. The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
38. Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus
39. “Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes
40. Structure–Function Studies of the Antibiotic Target l,l-Diaminopimelate Aminotransferase from Verrucomicrobium spinosumReveal an Unusual Oligomeric Structure
41. Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus.
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