25 results on '"Creemers, John W.M."'
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2. The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
3. Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function
4. Transgenic Artifacts Caused by Passenger Human Growth Hormone
5. Proprotein convertase furin regulates osteocalcin and bone endocrine function
6. Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression
7. The AlfpCre mouse revisited: Evidence for liver steatosis related to growth hormone deficiency
8. Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate
9. Deletion of PREPL, a gene encoding a putative serine oligopeptidase, in patients with hypotonia-cystinuria syndrome
10. Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity
11. SCAMP5, NBEA and AMISYN: three candidate genes for autism involved in secretion of large dense-core vesicles
12. PREPL: a putative novel oligopeptidase propelled into the limelight
13. Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
14. A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
15. Loss of in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction.
16. Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism.
17. Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice.
18. The Dfur2 Gene of Drosophila melanogaster: Genetic Organization, Expression During Embryogenesis, and Pro-Protein Processing Activity of Its Translational Product Dfurin2.
19. Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene.
20. Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer.
21. Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes
22. Endosome to trans-Golgi network transport of Proprotein Convertase 7 is mediated by a cluster of basic amino acids and palmitoylated cysteines.
23. Curcumin affects proprotein convertase activity: Elucidation of the molecular and subcellular mechanism.
24. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice
25. Proprotein convertases in human atherosclerotic plaques: The overexpression of FURIN and its substrate cytokines BAFF and APRIL
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