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This study is aimed to synthesize zinc oxide nanoparticles (ZnO NPs) from Aloe barbadensis Miller leaf extract using the green synthesis method at room temperature. The biosynthesized NPs are characterized by X‐ray diffraction (XRD), UV–vis spectroscopy (UV–vis), Fourier transform infrared (FTIR) spectroscopy, and scanning electron microscope (SEM). The XRD pattern has revealed the hexagonal wurtzite structure with a crystallite size of 16 nm for synthesized ZnO NPs. The FTIR results display the formation of ZnO NPs and the presence of other functional groups. The UV–vis absorption spectrum shows an absorption band at 347 nm and the value of the bandgap is found to be 3.75 eV. The surface morphology of synthesized NPs is visualized by SEM images, it is observed that most of the NPs are needle in shape. Further, these NPs will find applications in biosensing and photocatalytic activity. [ABSTRACT FROM AUTHOR]

Abstract: A series of novel 2,3‐dihydroquinazolin‐4(1H)‐ones 7 a‐g were designed, synthesized and were characterized by IR, 1H & 13C NMR, MS, and elemental analysis. The optical and electrochemical properties have been studied using UV‐Vis absorption, fluorescence spectroscopy, life time and cyclic voltammetry (CV) measurements. Quantum yield and effect of solvents for the compounds 7 a‐g were investigated. Density Functional Theory (DFT) computations have been carried out for all the synthesized compounds and the computed values found to be approximately in close agreement with the experimental results. Further, the compounds 7 a, 7 d, 7 f and 7 g were evaluated for their anticancer activity at National Cancer Institute, NIH, Bethesda, USA and have shown moderate to good anticancer activities. [ABSTRACT FROM AUTHOR]