Search

Your search keyword '"Chen, Qijun"' showing total 443 results
Start Over Author "Chen, Qijun" Search Limiters Academic (Peer-Reviewed) Journals
443 results on '"Chen, Qijun"'

3. PASTS: Progress-Aware Spatio-Temporal Transformer Speaker For Vision-and-Language Navigation

Author

Wang, Liuyi, Liu, Chengju, He, Zongtao, Li, Shu, Yan, Qingqing, Chen, Huiyi, and Chen, Qijun

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Vision-and-language navigation (VLN) is a crucial but challenging cross-modal navigation task. One powerful technique to enhance the generalization performance in VLN is the use of an independent speaker model to provide pseudo instructions for data augmentation. However, current speaker models based on Long-Short Term Memory (LSTM) lack the ability to attend to features relevant at different locations and time steps. To address this, we propose a novel progress-aware spatio-temporal transformer speaker (PASTS) model that uses the transformer as the core of the network. PASTS uses a spatio-temporal encoder to fuse panoramic representations and encode intermediate connections through steps. Besides, to avoid the misalignment problem that could result in incorrect supervision, a speaker progress monitor (SPM) is proposed to enable the model to estimate the progress of instruction generation and facilitate more fine-grained caption results. Additionally, a multifeature dropout (MFD) strategy is introduced to alleviate overfitting. The proposed PASTS is flexible to be combined with existing VLN models. The experimental results demonstrate that PASTS outperforms all existing speaker models and successfully improves the performance of previous VLN models, achieving state-of-the-art performance on the standard Room-to-Room (R2R) dataset., Comment: 15 pages, 11 figures

Published
2023
Full Text
View/download PDF

36. Experiment on Inhibiting NEK7 to Promote Apoptosis of Hepatocellular Carcinoma Cells

Author

SONG Yanzhou, ZHANG Kun, CHEN Qijun, WEI Wenping, ZHAO Xin, LI Zhiwei, and LI Wei

Subjects
hepatocellular carcinoma, nek7, cell cycle, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Objective To use in vitro experiments to verify the changes of proliferation, senescence and apoptosis of hepatocellular carcinoma cells after inhibiting the expression of NEK7, and to explore the related molecular mechanism. Methods Western blot and RT-PCR were used to detect the expression of NEK7 in hepatocellular carcinoma cells and THLE-2 cells. A viral vector was designed to inhibit the expression of NEK7 based on the gene sequence. After hepatocellular carcinoma cells were transfected, we observed the changes of proliferation activity, cell senescence, cell apoptosis and cell cycle in vitro. Western blot was used to detect the expression of cell cycle-related factors. Results Compared with THLE-2 cells, NEK7 was highly expressed in hepatocellular carcinoma cells. After inhibiting the expression of NEK7 with shRNA, the proliferation of hepatocellular carcinoma cells was inhibited, the proportions of cell senescence and apoptosis were increased, meanwhile, the cell number in stage S and G2/M was significantly reduced, the cell cycle progression was blocked, the expression levels of C-myc, c-Fos, cyclin D1 and cyclin E were inhibited, P16 and P27 expression were increased, and CDK2, CDK4 and CDK6 expression were not significantly changed. Conclusion After inhibiting the expression of NEK7, the proliferation ability of hepatocellular carcinoma cells is reduced, cell senescence is promoted and apoptosis is induced; meanwhile, the cell cycle progress is blocked.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results