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Ten cases of acute myeloperoxidase-negative myeloid leukaemia (AML) were reported. They had no typical mopholocid negative for lymphocic features and were negative antigens. However 5 cases were positive for NSE/NaF stain. 9 of the 10 cases expressed more than one myeloid antigens. The authors are of the opinion that it is very difficult to diagnose myeloperoxidase-negative AML and combination of cytochemical and immunological techniques is recommended in this respect.

Ten leukemic patients were treated with allogeneic bone marrow transplantation (BMT). The diagnosis were ANLL in 6 cases, CML in 3 and ALL in one. Pretransplant immuno suppressive measures including total body irradiation cyclophosphamide and daunorubicin were given. All the patients were infused with health stem cell preparation, so that the hemopoietic function was restored. Graft versus-host disease of grade I to II was present in 5 of the patients. Leukemia recurred 76 days after BMT in one patient who received the procedure during a relapse of the disease, while in the remaining 9 patients disease-free survival from 1 to 23 months has been observed.

The authors presented 5 cases of ANLL and 6 cases of ALL according to FAB classification and further classified them with leukemic cell morphology, cytochemistry and immunophenotyping. Five cases of them belonged to low grade peroxidase ANLL (LP-ANLL), 4 to hybrid acute leukemia (HAL) and 2 to acute undifferentiated leukemia (AUL). The importance of immunophenotyping of leukemic cells in classification of acute leukemia was emphasized and the criteria for diagnosis of LP-ANLL, HAL and AUL discussed. The authors are of the opinion that the diagnosis of these three kinds of acute leukemia is difficult and the prognosis is serious.