Search

The old female population of Pakistan is suffering more from diabetes as this is may be due to eating habits and obesity. The main objective of the study is to find the relationship of obesity, and diabetes in old female population of Pakistan. This cross sectional study was conducted in CIMS, Bahawalpur during January 2019 to October 2019. This study was based on local female population of Lahore, age range from 30 to 50 who was suffering from diabetes and they are also obese. This study was done with the permission of hospital ethical committee and with the written consent of patients. First of all we collect the demographic data of all females, it includes living habits, eating habits, social and economic back ground. The mean age (±SD) was 40 ± 10 years. Mean duration of diabetes was 5 years, mean HbA1c was 8.1% and 53.7% were on oral agents and rest was on insulin with or without oral agents. Hypertension was present in 65.7%, 13.7% had known coronary artery disease and 2.3% had a cerebrovascular accident previously. According to the analysis of data there is a positive correlation between obesity and diabetes in the environment like Pakistan. Because female suffer from hypertension, weight gain and due to this from diabetes.

The main objective of the study is to find the role of antioxidants in diabetic HCV patients in Pakistan. This cross sectional study was conducted in CIMS, Bahawalpur during January 2019 to October 2019. This study was conducted according to the rules and regulations of authority. For this research purpose we selected 50 individuals of both genders. This study was carried out on 50 patients who were categorized into three groups i.e., control, HCV patients and HCV/diabetes patients. The blood was collected from a cuboital vein of patients and serum was separated within one hour ny centrifugation. Our results shows that antioxidants are the important biomarkers for the diagnosis of liver problems in diabetic patients. The level of SOD, CAT, GSH and MDA were decreases in diabetic HCV patients as compared to normal and simple HCV patients. The important biomarker is MDA and SOD. It is concluded that antioxidants levels have been related to various disease processes and play a significant role in the pathogenesis of diabetic complications. Their plasma levels are usually used as a marker of lipid peroxidation. Plasma MDA, SOD, GSH and CAT was elevated in chronic hepatitis C and liver cirrhosis patients.