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Your search keyword '"Sergio Vañó-Galván"' showing total 2 results
Start Over Author "Sergio Vañó-Galván" Publisher wolters kluwer medknow publications
2 results on '"Sergio Vañó-Galván"'

2. Perforating dermatosis in a patient receiving azathioprine

Author

Emiliano Grillo, Sergio Vano-Galván, Carmen Moreno, and Pedro Jaén

Subjects
Azathioprine, drug reactions, perforating dermatosis, Dermatology, RL1-803
Abstract

Azathioprine (AZA) is an imidazole derivative of mercaptopurine. It antagonizes purine metabolism, and it may inhibit synthesis of DNA, RNA, and proteins. The 6-thioguanine nucleotides appear to mediate the majority of AZAs immunosuppressive and toxic effects. While cutaneous adverse side-effects are not uncommon, perforating dermatosis has not been reported in association to AZA. We speculate that immunological disorders induced by AZA in susceptible individuals could be related to perforating dermatosis.

Published
2013
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