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Background: The occurrence of root resorption (RR) is an unavoidable result of orthodontic treatment. Finding a straightforward approach to its prevention remains a challenge. It is a tragic occurrence when radiographically detected, even though it is rarely severe. The application of force starts a sequence of biological mechanisms. Although we are well aware of how and when it is provoked, we are unable to foresee what will happen in the end. In the past few years, clear aligner therapy has become very popular. Although not much data has been established describing RR after this treatment. Aim: The following review determines the effect of aligner therapy on the resorption of roots leading to the shortening of root length. Methods: Research publications were searched on search engines such as Scopus, PubMed, and Google Scholar using terms such as "RR," "risk factors of RR" and "effects of clear aligner therapy on RR." These publications were then collected. Results: For this review, 30 articles were collected and further used to formulate this review. Conclusion: (1) Most affected teeth were the maxillary central and lateral incisors post aligner therapy. (2) Multiple factors that influenced RR were gender, malocclusion, the severity of crowding, type of tooth movement, and close approximation of root toward the cortical plate (3) Clear aligner therapy is comparable to LightForce fixed orthodontics appliances but surpasses heavy-force orthodontic appliances in the terms of the risk associated with developing RR. [ABSTRACT FROM AUTHOR]

Background: The aim of this study was to quantify the number of mast cells in focal reactive hyperplastic lesions of the oral cavity and to compare these two number of mast cells in normal gingival tissues and to correlate their presence with the state of connective tissue changes in reactive lesions and probably suggest a role for mast cells in these lesions. Materials and Methods: Patient records were retrieved during a 10 year period from 2001 to 2010. Data of all reactive hyperplasias namely focal fibrous hyperplasia, pyogenic granuloma (PG), peripheral ossifying fibroma (POF) and peripheral giant cell granuloma (PGCG) were reviewed and 10 cases seen in the gingiva were selected for each category and stained with 1% toluidine blue for mast cells. Statistical analysis was applied to see the significant differences between the groups and with the normal gingival tissue. One-way ANOVA-F and unpaired t-test was applied and significant differences were seen between the groups at 5% level of significance. Results: In this study, mast cell count was maximum in POF and fibrous hyperplasia (FH) followed by cases of PG and PGCG. Conclusion: The number of mast cells was more numerous in POF and FH suggesting that mast cell activation is a characteristic feature of chronic inflammation, a condition that may lead to fibrosis as a result of increased collagen synthesis by fibroblasts. [ABSTRACT FROM AUTHOR]

Pleomorphic adenoma (PA) is the most common benign tumor of major or minor salivary glands. Microscopically, PA exhibits a great diversity of morphological aspects. Here, we present an unusual case of PA with extensive squamous metaplasia and keratin-filled cysts in the left retromolar region of a 50-year-old edentulous person whose microscopic finding may represent a diagnostic dilemma for pathologists. [ABSTRACT FROM AUTHOR]