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Objectives: The aim of this study is to evaluate the safety of laparoscopic cholecystectomy to treat acute cholecystitis during pregnancy. Materials and Methods: We conducted a retrospective multicenter study including pregnant women with acute cholecystitis managed in surgery departments in Tunisia from January 1, 2015, to December 31, 2019. Results: Seventeen centers of surgery department participated in this study including 107 cases of acute cholecystitis. The average maternal age was 30.5 years. Nonoperative management was performed in eight patients, whereas 99 other patients had surgery. Postoperative follow-up was uneventful in 93.8% of cases and eventful in 6.2% of cases. There was no mortality as far. A medical complication occurred in two patients with a medical morbidity rate of 1.7%. It was about thromboembolic disease. A surgical complication occurred in two other patients with a surgical morbidity rate of 1.7%. It was about intraperitoneal infection in one case and biliary collection in the other case. In univariate analysis, variables related significantly to maternal complication were: age equal or over 35 years old (P = 0.001), jaundice (P = 0.024), C-reactive protein value equal or over 20 mg/L (P = 0.05), and biliary peritonitis (P = 0.05). In multivariate analysis, independent variable predictive of maternal complications was age equal or over 35 years old (P = 0.003), jaundice (P = 0.003), and biliary peritonitis (P = 0.011). Conclusion: Laparoscopic cholecystectomy for cholecystitis can be safely achieved in pregnant women with low rates of morbidity and mortality. This study showed that independent variable predictive of maternal complications was age equal or over 35 years old, jaundice, and biliary peritonitis. [ABSTRACT FROM AUTHOR]

Background: Gastric cancer is a cancer with a poor prognosis. Surgery with adequate lymph node dissection is the only potentially curative treatment for gastric cancer. The aim of this work is to determine the prognostic factors after curative resection for gastric cancer. Patients and Methods: We retrospectively assessed 66 patients who underwent operation for gastric cancer (excluding the eso gastric junction cancer) in a single institution between 2001 and 2015. Results: There were 25 women and 40 men. The median age was 60 years (21-87). Four patients died (6.1%). A total gastrectomy was performed in 35 cases, and a subtotal gastrectomy was performed in 30 cases. The type of lymphadenectomy was D2 lymphadenectomy in 35 cases and D2 without splénectomy in 30 cases. The pathologic review of the slides revealed that the tumors were stage T3-T4 in 49 cases. The median number of lymph node removed was 14. Median survival rate was 34 months. The median follow-up was 24 months. In multivariate analysis, the location in the fundus, lymph nodes involvement, and involvement of located organs were associated with poor prognosis. Conclusion: After R0 resection with DII lymphadenectomy, fundus location, lymph node Involvement, and involvement of organs were independent predictive factors for survival. [ABSTRACT FROM AUTHOR]