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Your search keyword '"Stafler, P."' showing total 2 results
Start Over Author "Stafler, P." Publisher williams & wilkins
2 results on '"Stafler, P."'

1. Clinical Impact of β-Lactamase-producing Enterobacteriaceae in Sputum of Cystic Fibrosis Patients.

Author

Mussaffi H, Shvalb NF, Ben-Zvi H, Livni G, Mei-Zahav M, Prais D, Stafler P, Steuer G, and Blau H

Subjects
Adolescent, Adult, Carrier State microbiology, Child, Child, Preschool, Cohort Studies, Cystic Fibrosis complications, Enterobacteriaceae Infections epidemiology, Female, Hospitalization, Humans, Infant, Israel epidemiology, Male, Middle Aged, Prevalence, Young Adult, Cystic Fibrosis microbiology, Enterobacteriaceae enzymology, Enterobacteriaceae isolation & purification, Enterobacteriaceae Infections microbiology, Sputum microbiology, beta-Lactamases metabolism
Abstract

This case series describes 18 cystic fibrosis (CF) patients of a 135-patient CF center cohort with extended spectrum β-lactamase-producing Enterobacteriaceae, from 2003 to 2012. Four had chronic infection. Prevalence increased annually from 0 to 6.35%. Risk factors compared with the 2010 CF center cohort included continuous inhaled antibiotics (P = 0.014) and courses of intravenous antibiotics during the year before first isolation (P = 0.009). Hospitalization rates were 1.05/year and 0.47/year preinfection and postinfection, respectively (P = 0.02). Slope of forced expiratory volume at 1 second% predicted remained unchanged during 12 months.

Published
2016
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2. The Spectrum of Nocardia Lung Disease in Cystic Fibrosis.

Author

Mei-Zahav M, Livnat G, Bentur L, Mussaffi H, Prais D, Stafler P, Bar-On O, Steuer G, and Blau H

Subjects
Adolescent, Adult, Aspergillosis, Allergic Bronchopulmonary, Child, Female, Humans, Israel, Lung Transplantation, Male, Middle Aged, Retrospective Studies, Sputum microbiology, Cystic Fibrosis complications, Nocardia, Nocardia Infections
Abstract

We reviewed all cases of Nocardia infection in cystic fibrosis patients at 2 centers. Eight of 200 patients had Nocardia in sputum. Four developed severe lung disease, including 3 with associated allergic bronchopulmonary aspergillosis; 4 remained clinically stable. Nocardia is often associated with significant lung disease in cystic fibrosis, possibly associated with allergic bronchopulmonary aspergillosis or steroids.

Published
2015
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