1. ChemPhotoChem / Accelerated Reaction Engineering of Photo(bio)catalytic Reactions through Parallelization with an Open-Source Photoreactor
- Author
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Winkler, Christoph, Simić, Stefan, Jurkaš, Valentina, Bierbaumer, Sarah, Schmermund, Luca, Poschenrieder, Silvan, Berger, Sarah A., Kulterer, Elisa, Kourist, Robert, and Kroutil, Wolfgang
- Subjects
Photokatalyse ,Photoreaktor ,Biocatalysis ,Photoreactor ,Photobiocatalysis ,Photocatalysis ,Reaktionsengineering ,Photobiokatalyse ,Reaction Engineering ,Biokatalyse - Abstract
Photobiocatalysis is an alternative approach in synthesis that received much attention in the recent years. Due to the youth of the topic, only few reactor systems are commercially available. To allow a parallel parameter-screening approach as it is often used in the optimization of biocatalytic processes, a photoreactor was developed that can illuminate up to 24 samples at well-defined reaction conditions. The device's optical features and temperature regulation have been thoroughly characterized and its applicability was demonstrated in four examples, including three photobiocatalytic, and one photocatalytic process: (i) The light dependent decarboxylation using a photodecarboxylase; (ii) the reduction of protochlorophyllide using a protochlorophyllide oxidoreductase; (iii) the photosynthetic oxygen production performed by cyanobacteria (iv) the (-)-riboflavin-catalyzed (E/Z)-isomerization of cinnamic acid derivatives. (VLID)6280987 Accepted version
- Published
- 2021