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Your search keyword '"long-term cognitive outcome"' showing total 2 results
Start Over Descriptor "long-term cognitive outcome" Publisher wiley-blackwell
2 results on '"long-term cognitive outcome"'

1. Cognitive outcome varies in adolescents born preterm, depending on gestational age, intrauterine growth and neonatal complications.

Author

Lundequist, Aiko, Böhm, Birgitta, Lagercrantz, Hugo, Forssberg, Hans, and Smedler, Ann‐Charlotte

Subjects
*PREMATURE infants, *GESTATIONAL age, *FETAL development, *LOW birth weight, *COGNITION disorders
Abstract

Aim The aim of this study was to investigate long-term cognitive outcome in a cohort of 18-year-olds born preterm and previously assessed at the age of 5.5. Methods We tested 134 adolescents born preterm with a very low birthweight of <1500 g and 94 term-born controls with a comprehensive cognitive battery at 18 years of age. The cohort was subdivided into 73 extremely preterm, 42 very preterm and 19 moderately preterm infants with gestational ages of 23-27, 28-31 and 32-36 weeks, respectively. The moderately preterm group was dominated by adolescents born small for gestational age. Results Very preterm adolescents performed on a par with term-born controls. In contrast, extremely preterm adolescents displayed inferior results on all cognitive tests, more so if they had suffered neonatal complications. Moderately preterm adolescents scored lower than very preterm and full-term born adolescents, particularly on complex cognitive tasks. Conclusion Adolescents born at 28 weeks of gestation or later, with appropriate birthweight and no perinatal complications, functioned like term-born peers at 18 years of age. Extremely preterm birth per se posed a risk for long-term cognitive deficits, particularly executive deficits. Adolescents born moderately preterm but small for gestational age were at risk of general cognitive deficits. [ABSTRACT FROM AUTHOR]

Published
2015
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2. Reflex myoclonic epilepsy in infancy. A multicenter clinical study

Author

Silvia Cappanera, Raffaella Marino, Raffaella Cusmai, Giuseppe Gobbi, Piero Pavone, Antonino Romeo, Pasquale Striano, Giangennaro Coppola, Tiziana Granata, Salvatore Striano, Federico Vigevano, Claudia D’Egidio, Salvatore Grosso, Dario Pruna, Alberto Verrotti, Alberto Spalice, Sara Matricardi, Emilio Franzoni, Pasquale Parisi, Giuseppe Capovilla, A., Verrotti, S., Matricardi, G., Capovilla, C., D'Egidio, R., Cusmai, A., Romeo, D., Pruna, P., Pavone, S., Cappanera, T., Granata, G., Gobbi, Striano, Pasquale, S., Grosso, P., Parisi, E., Franzoni, Striano, Salvatore, A., Spalice, R., Marino, F., Vigevano, G., Coppola, Alberto Verrotti, Sara Matricardi, Giuseppe Capovilla, Claudia D’Egidio, Raffaella Cusmai, Antonino Romeo, Dario Pruna, Piero Pavone, Silvia Cappanera, Tiziana Granata, Giuseppe Gobbi, Pasquale Striano, Salvatore Grosso, Pasquale Parisi, Emilio Franzoni, Salvatore Striano, Alberto Spalice, Raffaella Marino, Federico Vigevano, and Giangennaro Coppola

Subjects
Male, Idiopathic generalized epilepsy, Pediatrics, medicine.medical_specialty, Acoustic and/or tactile stimuli, Long-term cognitive outcome, Reflex myoclonic epilepsy in infancy, Valproate treatment, Child, Child, Preschool, Electroencephalography, Epilepsies, Myoclonic, Epilepsy, Reflex, Female, Follow-Up Studies, Humans, Infant, Infant, Newborn, Acoustic Stimulation, Touch, Neurology, Neurology (clinical), Epilepsies, Clinical study, Epilepsy, Reflex, medicine, myoclonic epilepsy in infancy, Preschool, medicine.diagnostic_test, Cognition, idiopathic generalized epilepsy, reflex myoclonic epilepsy in infancy, acoustic and/or tactile stimuli, long-term cognitive outcome, valproate treatment, Newborn, medicine.disease, Anesthesia, Myoclonic epilepsy, Long term outcome, Cognitive Assessment System, Myoclonic, Psychology
Abstract

Summary Purpose To describe the clinical and electroencephalographic (EEG) features of reflex myoclonic epilepsy in infancy (RMEI) and long-term cognitive outcome. Methods We enrolled 31 children from 16 neuropediatric centres in Italy, who underwent clinical and video-EEG evaluation. Cognitive assessment was performed in all patients using standardized psychometric tests. Results The age at onset ranged from 3 to 24 months of age. Seizures were characterised in all patients by symmetric myoclonic seizures (MS), triggered by sudden unexpected acoustic (38.7%) or tactile stimuli (29%) or both (29%). Spontaneous attacks were reported in 32.2% of the cases. Ictal EEG showed generalized high-amplitude 3 Hz polyspike and wave discharges, synchronous with brief rhythmic bursts of electromyographic activity. Patients were re-evaluated after a period of 7.2 ± 5.6 years. The prognosis for seizure control was excellent in all cases and reflex MS disappeared spontaneously or after valproate treatment. The cognitive outcome was excellent in 90.3% of children. Conclusions RMEI appears to be a variety of idiopathic generalized epilepsy with specific features that occurs in developmentally normal children.

Published
2013

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