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Objective: The study explored the mediating role of Chinese American parents' ethnic–racial identity (ERI) in linking their discrimination experiences, ethnic–racial socialization (ERS), and their children's mental health, testing whether neighborhood racial diversity and perceived Chinese density moderated these mediation paths. Background: During COVID‐19, Chinese American families faced increased discrimination, impacting their mental well‐being. However, few studies have examined how parents' discrimination experiences influence their ERI, ERS practice, and ultimately their children's mental health difficulties. Method: Data from 294 Chinese immigrant parents (Mage = 44.28, 79% female) were collected in two waves, 2020 and 2021. Path analysis tested if parental discrimination affects their ERI and ERS, and children's mental health. Multigroup analysis assessed if mediation models varied for families living in communities with low versus high racial diversity or Chinese density. Results: Parental racism‐related stress at T1 had significant indirect effects on parental ERS practices (higher use of maintenance of heritage culture and lower use of avoidance of outgroups practice) at T2 via parental ERI (greater private regard) at T2. Parental racial discrimination (perceived sinophobia in the media and racism‐related stress) at T1 had significant indirect effects on children's mental health difficulties at T2 via parental ERS practices (use of maintenance of heritage culture and avoidance of outgroups practices) at T2. The neighborhood racial diversity moderated the mediation model. Conclusion: These findings advance the understanding of both individual (i.e., parental ERI) and contextual factors (i.e., neighborhood racial diversity) in the complex associations between parents' discrimination experiences and children's mental health difficulties. [ABSTRACT FROM AUTHOR]

Bullying is prevalent in many schools worldwide. Providing bullying prevention training to preservice teachers can make a significant difference in preventing school bullying. There is a lack of training in bullying prevention for preservice teachers in China, and the effectiveness of such training for bullying prevention has not yet been established. The present study examined the effectiveness of bullying prevention training on antibullying self‐efficacy and incorrect beliefs about bullying among Chinese preservice teachers. A total of 139 preservice teachers (Mage = 20.76 years, SD = 0.80 years, ranging from 19 to 23 years; 90.6% women) were randomly assigned to the bullying prevention training (n = 73) or the control group (n = 66). Preservice teachers completed pre‐ and posttraining surveys. The participants in the treatment group completed a 5‐week bullying prevention training program (1.5 h per week). Measures of antibullying self‐efficacy and incorrect beliefs about bullying were used to evaluate the effectiveness of the bullying prevention training. Results indicated that the training increased preservice teachers' antibullying self‐efficacy but did not decrease their incorrect beliefs about bullying. Practical implications, limitations, and future directions of these findings are discussed. Practitioner Points: Bullying prevention training resulted in an increase of preservice teachers' antibullying self‐efficacy.The training did not decrease preservice teachers' incorrect beliefs about bullying.Incorporating bullying prevention training into the preservice teacher education curriculum is essential. [ABSTRACT FROM AUTHOR]

Background: The present longitudinal study investigated parenting style as a precursor for Chinese adolescents' stress‐related growth and mental health difficulties during the COVID‐19 pandemic, as well as the mediating roles of intrapersonal resilience and interpersonal relationships (i.e., peer and parent−adolescent). Methods: Chinese adolescents in a middle school (7th grade) and their parents in Beijing, China, were invited to complete a survey at two time points (T1: September 2020, T2: June 2021). A total of 206 adolescents (52.9% boys; Mage = 12.90 years, SDage = 0.33) and parents (17.5% fathers, 82.4% mothers; Mage = 43.50 years, SDage = 4.76 years) were included in this study. Results: Results showed that Chinese parents' authoritarian, not authoritative parenting, predicted adolescents' mental health difficulties nine months later. In addition, parent−adolescent relationships, but not peer relationships nor resilience, mediated the relations between parenting style and stress‐related growth. Adolescents' resilience predicted fewer mental health difficulties. Conclusion: It is important to target multiple ecologies (e.g., family) of adolescents for promoting positive adjustment. [ABSTRACT FROM AUTHOR]

Drug resistance remains the greatest challenge in improving outcomes for cancer patients who receive chemotherapy and targeted therapy. Surmounting evidence suggests that a subpopulation of cancer cells could escape intense selective drug treatment by entering a drug‐tolerant state without genetic variations. These drug‐tolerant cells (DTCs) are characterized with a slow proliferation rate and a reversible phenotype. They reside in the tumor region and may serve as a reservoir for resistant phenotypes. The survival of DTCs is regulated by epigenetic modifications, transcriptional regulation, mRNA translation remodeling, metabolic changes, antiapoptosis, interactions with the tumor microenvironment, and activation of signaling pathways. Thus, targeting the regulators of DTCs opens a new avenue for the treatment of therapy‐resistant tumors. In this review, we first provide an overview of common characteristics of DTCs and the regulating networks in DTCs development. We also discuss the potential therapeutic opportunities to target DTCs. Last, we discuss the current challenges and prospects of the DTC‐targeting approach to overcome acquired drug resistance. Reviewing the latest developments in DTC research could be essential in discovering of methods to eliminate DTCs, which may represent a novel therapeutic strategy for preventing drug resistance in the future. [ABSTRACT FROM AUTHOR]

Compared to their school peers, Asian American youth report more internalizing symptoms, peer victimization, and higher rates of suicide, yet they underutilize mental health services at school. This study investigated the feasibility and effectiveness of a culturally responsive parent training program called Parent–Child Connect for Asian American parents at school. Forty‐eight Asian American parents (Mage = 42.98; SDage = 5.54, 79.2% female) participated in the parent training program. Parents reported significant increases in positive parenting (parental warmth, Cohen's d = 0.33; reasoning, d = 0.42; and autonomy granting, d = 0.54), and decreases in negative parenting (verbal hostility, d = 0.52; directiveness, d = 0.33; and shaming behavior, d = 0.38) after the intervention. They also reported significant increases in their sense of competence (d = 0.53) and satisfaction in communicating with their children (d = 0.43). Good attendance and high satisfaction from parents suggested high feasibility of the intervention. Fifteen parents attended two focus group interviews 6 weeks after the training. Parents reported improved empathy, parent–child communication, and self‐efficacy, and provided suggestions for future iterations of the training. We discuss how school psychologists can provide parent training and support ethnic minority families at school. Impact Statement: To support Asian American youth and parents, we implemented Parent–Child Connect, a culturally responsive parent training program with Asian American parents at school. Results suggest that it is a feasible and effective parenting intervention for Asian American parents in the school setting. [ABSTRACT FROM AUTHOR]