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Your search keyword '"Ye, Yunpeng"' showing total 6 results
Start Over Author "Ye, Yunpeng" Publisher wiley-blackwell
6 results on '"Ye, Yunpeng"'

1. Association between cerebral amyloid accumulation and synaptic density in Alzheimer's disease: A multitracer PET study: Neuroimaging: Imaging the human synapse in AD.

Author

O'Dell, Ryan S., Mecca, Adam P., Chen, Ming‐Kai, Godek, Tyler A., Harris, Joanna E., Bartlett, Hugh H., Banks, Emmie R., Kominek, Victoria L., Zhao, Wenzhen, Naganawa, Mika, Toyonaga, Takuya, Lu, Yihuan, Nabulsi, Nabeel B., Ropchan, Jim R, Ye, Yunpeng, Vander Wyk, Brent C., Varma, Pradeep, Arnsten, Amy F.T., Huang, Yiyun, and Carson, Richard E.

Published
2020
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2. In vivo measurement of widespread synaptic loss and associated tau accumulation in early Alzheimer's disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD.

Author

Mecca, Adam P., O'Dell, Ryan S., Chen, Ming‐Kai, Naganawa, Mika, Toyonaga, Takuya, Godek, Tyler A., Harris, Joanna E., Bartlett, Hugh H., Zhao, Wenzhen, Gallezot, Jean‐Dominique, Nabulsi, Nabeel B., Ropchan, Jim R., Ye, Yunpeng, Wyk, Brent C. Vander, Arnsten, Amy F.T., Huang, Yiyun, Carson, Richard E., and van Dyck, Christopher H.

Published
2020
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4. Modulation of nuclear internalization of Tat peptides by fluorescent dyes and receptor-avid peptides

Author

Shen, Duanwen, Liang, Kexian, Ye, Yunpeng, Tetteh, Elizabeth, and Achilefu, Samuel

Subjects
BIOMOLECULES, CHROMOSOMAL translocation, MUTAGENESIS, SOMATOSTATIN
Abstract

Abstract: The nuclear internalization of biomolecules by Tat peptide provides a mechanism to deliver drugs to cells. However, translocation of molecular imaging probes to the nucleus may induce undesirable mutagenesis. To assess the feasibility of retaining its cell permeating effect without nuclear translocation, Tat-peptide was conjugated with a somatostatin receptor (STR)-avid ligand (Oct) and labeled with fluorescent dyes. The results show that Tat-Oct-5-FAM (fluorescein 5′-carboxylic acid) remained in the cytoplasm of STR-positive AR42J cells. Co-incubation of Tat-Oct-5-FAM with ATP induced nuclear translocation. These data suggest that both dye and Oct-STR endocytosis complex could modulate nuclear internalization of Tat peptides. [Copyright &y& Elsevier]

Published
2007
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