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Achieving efficient efficiency and selectivity for the electroreduction of CO2 to value‐added feedstocks has been challenging, due to the thermodynamic stability of CO2 molecules and the competing hydrogen evolution reaction. Herein, a dual‐single‐atom catalyst consisting of atomically dispersed CuN4 and NiN4 bimetal sites is synthesized with electrospun carbon nanofibers (CuNi‐DSA/CNFs). Theoretical and experimental studies reveal the strong electron interactions induced by the electronegativity offset between the Cu and Ni atoms. The delicately averaged and compensated electronic structures result in an offset effect that optimizes the adsorption strength of the *COOH intermediate and boosts the CO2 reduction reaction (CO2RR) kinetics, notably promoting the intrinsic activity and selectivity of the catalyst. The CuNi‐DSA/CNFs catalyst exhibits an outstanding FECO of 99.6% across a broad potential window of −0.78– −1.18 V (vs the reversible hydrogen electrode), a high turnover frequency of 2870 h–1, and excellent durability (25 h). Furthermore, an aqueous Zn‐CO2 battery for CO2 power conversion is constructed. This atomic‐level electronegativity offset of the dual‐atom structures provides an appealing direction to develop advanced electrocatalysts for the CO2RR. [ABSTRACT FROM AUTHOR]

Purpose: To determine the diagnostic potential of apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM)-derived parameters for the differentiation of benign, intermediate, and malignant solid soft-tissue tumors.Materials and Methods: The Institutional Review Board approved this prospective study, and informed consent was obtained. IVIM imaging was performed in 64 patients including 44 benign, 6 intermediate, and 14 malignant solid soft-tissue tumors at 1.5T. The IVIM parameters of the soft-tissue tumors were assessed using the Kruskal-Wallis test. The diagnostic performance of the parameters was evaluated using receiver operating characteristic (ROC) analysis.Results: The ADC and true diffusion coefficient (D) values of malignancies (1.28 ± 0.31, 1.06 ± 0.23 [×10-3 mm2 /sec]) were significantly lower than those of intermediate (1.49 ± 0.54, 1.30 ± 0.50 [×10-3 mm2 /sec]), or benign soft-tissue tumors (1.62 ± 0.37, 1.36 ± 0.33 [×10-3 mm2 /sec]) (P = 0.007 and P = 0.009, respectively). In the differential diagnosis of malignancies from benign tumors, ADC demonstrated the highest area under the curve (Az) value (Az = 0.793). The perfusion fraction (f) values of intermediate soft-tissue tumors (8.41 ± 2.73) were significantly different from those of benign and malignant tumors (14.70 ± 5.37 [P = 0.002]; 14.44 ± 5.31 [P = 0.021]). f showed the highest Az value in differentiating intermediate from benign, and malignant soft-tissue tumors (Az = 0.90, and Az = 0.833, respectively). The pseudodiffusion coefficient (D*) values of malignant soft-tissue tumors (144.40 ± 24.88 [×10-3 mm2 /sec]) were significantly higher than those of benign tumors (124.96 ± 26.24 [×10-3 mm2 /sec]) (P = 0.019).Conclusion: IVIM imaging may be helpful for differentiating benign, intermediate, and malignant solid soft-tissue tumors.Level Of Evidence: 1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2017;46:1611-1618. [ABSTRACT FROM AUTHOR]

Aims Primary cardiac lymphoma ( PCL) is a rare neoplasm. PCL is fatal, unless it is diagnosed and treated early. Recently, a small number of cases of diffuse large B cell lymphoma ( DLBCL) arising within atrial myxoma have been reported in immunocompetent patients and showed aggressive histological features but an indolent clinical behaviour. Methods and results We present four unusual cases of Epstein-Barr virus ( EBV)-positive DLBCL arising within atrial myxoma with detailed clinical, histological, immunophenotypical and genotypical features in immunocompetent patients, and review the literature for 11 similar cases. All the patients appeared to have morphological features of DLBCL, B lineage immunophenotype, high proliferative index and latency type III of EBV infection. They achieved complete tumour resection without chemotherapy or radiotherapy after surgery and were healthy at 3- and 7-month and 7- and 10-year follow-ups, respectively. Conclusions We suggest that this lymphoma should be regarded as a unique DLBCL associated with chronic inflammation ( DLBCL- CI) because of an indolent clinical behaviour to avoid excessive or unnecessary treatments. In addition, early accurate diagnosis and complete resection of this tumour are crucial for optimal patient outcome. [ABSTRACT FROM AUTHOR]