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Your search keyword '"Weiss, R B"' showing total 16 results
Start Over Author "Weiss, R B" Publisher wiley-blackwell
16 results on '"Weiss, R B"'

1. Clinical trial of VP 16--213 (NSC 141540) I.V. twice weekly in advanced neoplastic disease: a study by the Cancer and Leukemia Group B.

Author

Nissen, Nis I., Pajak, Thomas F., Leone, Louis A., Bloomfield, Clara D., Kennedy, B. J., Ellison, Rose Ruth, Silver, Richard T., Weiss, Raymond B., Cuttner, Janet, Falkson, Geoffrey, Kung, Faith, Bergevin, Patrick R., Holland, James F., Nissen, N I, Pajak, T F, Leone, L A, Bloomfield, C D, Ellison, R R, Silver, R T, and Weiss, R B

Published
1980
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2. A randomized combined modality trial in small cell carcinoma of the lung: comparison of combination chemotherapy-radiation therapy versus cyclophosphamide-radiation therapy effects of maintenance chemotherapy and prophylactiv whole brain irradiation.

Author

Maurer, L. Herbert, Tulloh, Marchant, Weiss, Raymond B., Blom, Johannes, Leone, Louis, Glidewell, Oliver, Pajak, Thomas F., Maurer, L H, Tulloh, M, Weiss, R B, Blom, J, Leone, L, Glidewell, O, and Pajak, T F

Published
1980
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4. Quality of life for adult leukemia survivors treated on clinical trials of Cancer and Leukemia Group B during the period 1971-1988: predictors for later psychologic distress.

Author

Greenberg, Donna B., Kornblith, Alice B., Herndon, James E., Zuckerman, Enid, Schiffer, Charles A., Weiss, Raymond B., Mayer, Robert J., Wolchok, Silkaly M., Holland, Jimmie C., Greenberg, D B, Kornblith, A B, Herndon, J E, Zuckerman, E, Schiffer, C A, Weiss, R B, Mayer, R J, Wolchok, S M, and Holland, J C

Published
1997
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8. Pregnancy outcome in survivors of advanced Hodgkin disease.

Author

Janov, Abbe J., Anderson, James, Cella, David F., Zuckerman, Enid, Kornblith, Alice B., Holland, Jimmie C., Kanfor, Arlene F., Li, Frederick P., Janov, A J, Anderson, J, Cella, D F, Zuckerman, E, Kornblith, A B, Holland, J C, Kantor, A F, Li, F P, Henderson, E, and Weiss, R B

Published
1992
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15. Improved molecular diagnosis of dystrophinopathies in an unselected clinical cohort.

Author

Dent KM, Dunn DM, von Niederhausern AC, Aoyagi AT, Kerr L, Bromberg MB, Hart KJ, Tuohy T, White S, den Dunnen JT, Weiss RB, and Flanigan KM

Subjects
Codon, Nonsense, Cohort Studies, DNA chemistry, DNA genetics, DNA Mutational Analysis methods, Exons genetics, Frameshift Mutation, Gene Deletion, Gene Duplication, Humans, Muscular Dystrophy, Duchenne diagnosis, Mutagenesis, Insertional, Mutation, Missense, Phenotype, Polymorphism, Single-Stranded Conformational, Dystrophin genetics, Muscular Dystrophy, Duchenne genetics, Mutation
Abstract

Mutations in the DMD gene result in Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Readily available clinical tests detect only deletions of one exon or greater, which are found in approximately 60% of cases. Mutational analysis of other types of DMD mutations, such as premature stop codons and small frameshifting insertions or deletions, has historically been hampered by the large size of the gene. We have recently reported a method that allows the rapid and economical sequencing of the entire coding region of the DMD gene, and that is more sensitive than methods based on single-strand conformational polymorphism (SSCP) screening or other preliminary screening steps. Here we use single condition amplification/internal primer (SCAIP) sequencing analysis, in combination with multiplex amplifiable probe hybridization (MAPH) analysis of duplications, to report the frequency of mutations in a large cohort of unselected dystrophinopathy patients from a single clinic. Our results indicate that 7% of dystrophinopathy patients do not have coding region mutations, suggesting that intronic mutations are not uncommon. The availability of rapid and thorough mutation analysis from peripheral blood samples, along with an improved estimate of the percentage of non-coding region mutations, will be of benefit for improved genetic counseling and in identification of cohorts for clinical trials.

Published
2005
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16. Leukemic thyroiditis as the initial relapsing sign in a patient with acute lymphocytic leukemia and blast expression of the neural cell adhesion molecule.

Author

Byrd JC, Dow NS, Gaertner E, Hargis JB, Raber TR, Burrell L, and Weiss RB

Subjects
Adult, CD56 Antigen analysis, Female, Humans, Leukemia-Lymphoma, Adult T-Cell complications, Leukemia-Lymphoma, Adult T-Cell pathology, Lymphocyte Activation, Recurrence, Leukemia-Lymphoma, Adult T-Cell diagnosis, Neural Cell Adhesion Molecules analysis, Thyroiditis, Subacute etiology
Abstract

We report a patient with a history of T-cell ALL in remission who presented with symptoms and laboratory values consistent with subacute thyroiditis but was found to have leukemic thyroiditis as the first clinical manifestation of leukemic relapse. Bone marrow examination at this time demonstrated recurrent ALL. After successful re-induction with chemotherapy and an allogeneic bone marrow transplant this patient developed an isolated recurrence of her ALL manifested by symptomatic thyromegaly and a new mediastinal mass that was treated with irradiation. Despite no medullary recurrence of ALL, the patient developed pleuritic chest pain and shortness of breath and succumbed to pericardial extramedullary leukemia 9 months later. This to our knowledge is the third reported case of symptomatic ALL involvement of the thyroid gland and the first to be confirmed histologically. Furthermore, this patient had blast expression of the neural cell adhesion molecule (CD56), a cell surface marker that has not been studied in ALL but has previously been identified as a risk factor for extramedullary leukemia (EML) in acute non-lymphocytic leukemia. The authors hypothesize that CD56 expression in this patient might have contributed to her predisposition to EML.

Published
1997
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