1. A One-Pot Synthesis of Triazolodiazepines.
- Author
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Hooyberghs, Geert, Van Hove, Sofie, Jacobs, Jeroen, Van Meervelt, Luc, and Van der Eycken, Erik V.
- Subjects
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DIAZEPINES , *RING formation (Chemistry) , *COUPLING reactions (Chemistry) , *HETEROCYCLIC compounds , *CHEMICAL reactions - Abstract
A one-pot sequential A3-coupling-azidation-cyclisation approach leading to potentially biologically active diazepine analogues has been developed. The implementation of the A3-coupling reaction ensures diversity. Attention is given to this so far rarely studied structural motif of fused heterocyclic diazepines. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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