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Associations between CO/PVR and umbilical artery (UmA), middle cerebral artery (MCA) Z scores and uterine artery (UtA) pulsatility index (PI) were calculated with polynomial regression analysis. We included 233 participants, 81 with healthy pregnancies, 47 with PE, 65 with SGA/FGR and 40 with PE+SGA/FGR. Compared to controls, CO was lower in the SGA/FGR and PE+SGA/FGR groups and PVR was increased in all pathological groups. [Extracted from the article]

Fetal middle cerebral artery Doppler (MCA) is recognised as a marker of hypoxia in fetal growth restriction with a reduction in impedance classically described as the "brain sparing effect". We report elsewhere a relationship between maternal hemodynamic function and both uterine and umbilical impedance, and sought to investigate whether fetal middle cerebral artery Doppler was related to maternal cardiac output (CO) and peripheral vascular resistance (PVR) in healthy and complicated pregnancy. [Extracted from the article]

OC25.04: Fetal umbilical artery Doppler end-diastolic flow is associated with changes in maternal cardiovascular function: a three-centre study using different techniques We aim to assess whether fetal umbilical artery Doppler end diastolic flow (whether positive, absent or reversed) is associated with differences in maternal cardiac output (CO) and peripheral vascular resistance (PVR). Fetal umbilical artery Doppler PI was measured; and comparison of cardiovascular measurements were made between those cases with positive umbilical artery end diastolic flow (EDF) and those with negative or absent EDF. [Extracted from the article]

Uterine artery Doppler (UtAD) is an imperfect screening test for pre-eclampsia (PE) and fetal growth restriction (FGR), with better screening performance for early onset complications. We have shown that maternal cardiac output is lower than healthy pregnancies in women with PE+FGR and FGR and higher than healthy pregnancies in PE. Women between 24-40 weeks gestation were prospectively recruited into 3 groups - pre-eclampsia (PE, n=13), fetal growth restriction with or without pre-eclampsia (FGR/PE+FGR, n=32) and healthy controls (n=62). [Extracted from the article]

We sought to determine whether maternal cardiovascular hemodynamics were related to uterine artery (UtAD) and fetal umbilical artery Doppler (UAD) changes in healthy and complicated pregnancy. Women between 24-40 weeks gestation were prospectively recruited into 4 groups- pre-eclampsia (PE), fetal growth restriction (FGR), fetal growth restriction with pre-eclampsia (PE+FGR) and healthy pregnancies (control). There is a significant relationship between maternal CO and PVR and Doppler impedance in both the utero-placental and fetal-placental circulations in normal and pathological pregnancy outcome: lower CO and higher PVR being associated with increased UtA and UAD impedance. [Extracted from the article]

An abstract of the article "Cardiac output and total peripheral resistance in pregnancies with fetal growth restriction," by J. Tay and colleagues is presented.

An abstract of the article "Cardiovascular changes from pre-pregnancy to early pregnancy in relation to viability of pregnancy," by L. Foo and colleagues is presented.

An abstract of the article "Is maternal arterial function impaired in pregnancies with fetal growth restriction?," by J. Tay and colleagues is presented.

Compares the effects of proadrenomedullin N-terminal 20 peptide and adrenomedullin in the human vascular bed. Degree of vasodilative effects; Drug dosage and administration.

An abstract of the article "Assignment of gestational length based on last menstrual period, first trimester crown?rump length, ovulation and implantation timing" by A. Mahendru and others is presented.

An abstract of the research paper "Relationship Between Maternal Cardiovascular Adaptation Fetal Growth and Birthweight," by A. Mahendru and colleagues is presented.