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This article discusses the case of a 46-year-old woman who presented with left retro-orbital headaches and other symptoms. Magnetic resonance imaging (MRI) revealed a 2.7 cm pituitary mass. Intraoperative and histological examinations showed a poorly differentiated neoplasm with high mitotic counts and loss of nuclear SMARCB1/INI1 staining. Chromosomal microarray analysis and next-generation sequencing detected copy neutral loss of heterozygosity (cnLOH) in chromosome 22 and a frameshift deletion in the SMARCB1 gene. The tumor was classified as an adult sellar atypical teratoid/rhabdoid tumor (AT/RT) and was found to be of the MYC subtype. The article emphasizes the rarity of adult sellar AT/RT and the importance of accurate diagnosis through molecular and cytogenetic analysis. [Extracted from the article]

Abstract: Objective: To review the clinical aspects of ovarian hyperstimulation syndrome and provide recommendations on its diagnosis and clinical management. Outcomes: These guidelines will assist in the early recognition and management of ovarian hyperstimulation. Early recognition and prompt systematic supportive care will help avert poor outcomes. Evidence: Medline, Embase, and the Cochrane database were searched for relevant articles, using the key words “ovarian hyperstimulation syndrome” and “gonadotropins,” and guidelines created by other professional societies were reviewed. Values: The quality of evidence was rated using the criteria described in the Report of the Canadian Task Force on Preventive Health Care. Recommendations for practice were ranked according to the method described in that report (Table 1). [Copyright &y& Elsevier]

Objective: To review the clinical aspects of ovarian hyperstimulation syndrome and provide recommendations on its diagnosis and clinical management.Outcomes: These guidelines will assist in the early recognition and management of ovarian hyperstimulation. Early recognition and prompt systematic supportive care will help avert poor outcomes.Evidence: Medline, Embase, and the Cochrane database were searched for relevant articles, using the key words "ovarian hyperstimulation syndrome" and "gonadotropins," and guidelines created by other professional societies were reviewed.Values: The quality of evidence was rated using the criteria described in the Report of the Canadian Task Force on Preventive Health Care. Recommendations for practice were ranked according to the method described in that report (Table 1). [ABSTRACT FROM AUTHOR]