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At least three clinical variations of idiopathic ulceration of the oropharyngeal cavity are recognized. Major (or giant) aphthous ulceration is uncommon but may affect the hypopharynx producing severe pain, dysphagia, and severe scarring. Healing with systemic prednisolone may require large and prolonged dosage. In 7 out of 14 patients with hypopharyngeal ulceration gastrostomy was performed to assist nutrition and by-pass the cricopharyngeal region in an attempt at reducing subsequent scarring.

Although differentiation of Wegener's granulomatosis from other destructive midline lesions is now clearly recognized by clinicians and pathologists, confusion persists regarding the management of what has erroneously been called "lethal midline granuloma." The experiences of 36 patients with destructive midline granuloma supports the view that probably all are manifestations of malignant lymphoma and should be treated as such. Although radical dosage radiotherapy will control most local lesions, dissemination of lymphoma may still occur despite absence of systemic disease at initial diagnostic work-up. Subsequent control with cytotoxic drugs is frequently unsuccessful, and it is suggested that chemotherapy should be given routinely to every patient with primary nasal lymphoma and possibly to those with polymorphic reticulosis or necrosis with atypical cellular exudate (NACE).

Two studies were conducted examining the stimulus-control effects of conventional traffic signs as prompts for motor vehicle driver safety belt use. Following pilot research which suggested that a traffic sign reading "Fasten Safety Belt" posted at a parking lot exit was effective in producing small increases in safety belt use, Study I demonstrated the superiority of having human prompters display such signs compared to simply posting the signs. Study II replicated the findings of Study I and found that posted signs became more effective in prompting safety belt use if simple posting was preceded by a period involving human prompters who displayed the signs. The results bear upon the development of more effective use of traffic signs in promoting safety belt use and in viewing such use as an instance of rule-governed behavior.