1. Effectiveness of a miswak extract-containing toothpaste on gingival inflammation: a randomized clinical trial.
- Author
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Azaripour, A, Mahmoodi, B, Habibi, E, Willershausen, I, Schmidtmann, I, and Willershausen, B
- Subjects
GINGIVAL hyperplasia ,CHI-squared test ,DENTIFRICES ,HERBAL medicine ,RESEARCH funding ,STATISTICS ,T-test (Statistics) ,DATA analysis ,RANDOMIZED controlled trials ,DATA analysis software ,DESCRIPTIVE statistics ,MANN Whitney U Test ,KRUSKAL-Wallis Test ,ONE-way analysis of variance ,PREVENTION - Abstract
Objectives In this study, the efficacy of a miswak extract-containing toothpaste ( Salvadora persica) on gingival inflammation was compared with that of a herbal and a conventional toothpaste. Methods Non-smoking outpatients with sulcus bleeding index ( SBI) ≥25% and with periodontal pocket depths ≤3 mm were randomly selected and divided into three groups: M-group, miswak extract-containing toothpaste; P-group, herbal toothpaste; and C-group, conventional toothpaste. After instructing the patients to brush their teeth twice a day for 3 weeks with the assigned toothpaste using a flat-trimmed manual toothbrush, a thorough oral examination was performed by a calibrated examiner ( EH). The primary outcome was the SBI after 21 days. Furthermore, the amount of plaque was measured by approximal plaque index ( API). Results Sixty-six patients with a mean age of 57.8 ± 10.2 years were recruited and enrolled. After 3 weeks of brushing, all three patient groups showed a significant reduction in SBI. The P-group ( SBI reduction: 17.1% ± 9.1) and the M-group (14.5% ± 8.1) showed the strongest effect followed by the C-group (9.4% ± 7.8). All three groups showed a significant reduction in API without significant differences between the groups. Conclusions The use of each of the three tested toothpastes caused a significant reduction in gingival inflammation and amount of plaque. The miswak extract-containing toothpaste showed a similar effect as the herbal toothpaste and can be safely used for domestic oral hygiene in patients with gingivitis. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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