Search

To quantitatively determine testicular tissue stiffness values using shear wave elastography (SWE) in males that have sickle cell anemia (SCA) and to evaluate the relationship between elastography results and semen analysis parameters and hormone levels. Fifty patients diagnosed with SCA and followed up in the hematology outpatient clinic were evaluated in the urology outpatient clinic as the study group. In addition, there were 88 patients without any SCA‐related complaints in the control group. We compared these groups with respect to their values, spermiogram parameters, testicular volume, and SWE values. Among patients in the SCA group, 28% had impaired sperm parameters. When testicular elastography was assessed, the testicular volumes were materially lower in the SCA group in comparison to the control group [right testicular volume: 14.76 (12.77–18.12) and 19.68 (15.12–24.18), respectively, p < 0.001; left testicular volume: 14.11 (11.06–17.32) and 16.59 (13.38–20.13), respectively, p = 0.015]. Additionally, the left testis central stiffness and the left testis inferior stiffness were significantly higher in the SCA group (p < 0.001 and p = 0.014, respectively). The age and hydroxyurea use had a worse effect on sperm parameters in patients with SCA (odds ratio: −0.161 and −1.914, standard deviation: 0.071 and 0.921, and p = 0.024 and p = 0.038, respectively). We consider that the technique utilized in this study for SWE values is fast and can be adopted as a reliable diagnostic tool and follow‐up practice in routine clinical practice to evaluate the acuteness of damage to the testicles in patients having SCA. [ABSTRACT FROM AUTHOR]

Background: TRUS biopsy is the preferred method for diagnosing prostate cancer, but it can cause infectious complications that arise with the contribution of fluoroquinolone resistance. We aimed to explore the potential protective effect of a second rectal enema before biopsy. Methods: From January 2015 to December 2020, 419 patients were assessed retrospectively. Patients with a history of anticoagulant use, uncontrolled diabetes, urological surgery, prostate biopsy or recent hospitalisation or overseas travel, as well as those with the previous prostatitis, were excluded from the study. The patients were subsequently divided into two groups: Group 1 (n = 223) had received one enema, on the morning of the biopsy and Group 2 (n = 196) had received two, with the additional enema administered half an hour before the procedure. Results: There was no significant difference between the groups in terms of age(P =.076), BMI (P =.489), diabetes (P =.265), prostate‐specific antigen (PSA) level (P =.193), free/total PSA (f/t PSA) ratio (P =.518) and prostate size (P =.661) or in relation to cancer detection (P =.428). The median hospitalisation date was significantly higher in Group 1 (P =.003) as was urinary tract infection (UTI) development (P =.004). However, there was no significant difference in terms of fever and sepsis (P =.524 and P =.548, respectively). Additionally, subgroup analysis demonstrated that UTI was significantly lower in patients with diabetes mellitus who had received a second enema (P =.004), though there was no significant difference in UTI between the groups in those without diabetes mellitus (P =.215). Multivariable analysis showed that age and diabetes were significant risk factors for the development of UTI (OR: 1.074, 95% CI: 1.027‐1.130, P =.002 and OR: 1.220, 95% CI: 0.131‐0.665, P =.003, respectively). Furthermore, the second enema was a significant protective factor for preventing UTI (OR: −1.794, 95% CI: 2.208‐16.389, P <.001). Conclusion: Older age and the presence of diabetes mellitus are independent risk factors for UTI after prostate biopsy. A second enema procedure before biopsy may protect patients from related infectious complications and could therefore be used as an alternative preventative method. [ABSTRACT FROM AUTHOR]

Background: Obesity has been associated with severe conditions and sexual dysfunction. Bariatric surgery has effects positively patients' sexual function. Objectives: To assess the effect of bariatric surgery on sexual functions of couples. Materials and Methods: The study included 57 obese patients and their sexually active partners. Male participations were assessed with the International Index of Erectile Function (IIEF) and Male Sexual Health Questionaries (MSHQ‐4), and female participations were assessed with the Female Sexual Function Index (FSFI). Results: There were 31 (54.4%) male patients and 26 (45.6%) female patients in the study. The median IIEF score of the male patients statistically increased postoperatively (p < 0.001). The IIEF subgroup areas were found to have increased after surgery. The median FSFI score of the female patients statistically increased postoperatively (p < 0.001). The median FSFI of male patients' partners significantly increased postoperatively (p < 0.001). All FSFI domains were statistically significantly increased (p < 0.001, all areas). The median IIEF value of the postoperative partners of the female patients also increased statistically significant (p < 0.001). In addition, the increases in the IIEF's subdomains in terms of sexual desire (p < 0.001), intercourse satisfaction (p < 0.001), and general satisfaction (p < 0.001) were statistically significant. Conclusion: The sexual functions of both males and females and also their' partners were improved after bariatric surgery. Patients with preoperative poor sexual function achieve significant benefits over patients without sexual dysfunction. [ABSTRACT FROM AUTHOR]

Introduction: Following the COVID‐19 pandemic, the face‐to‐face meetings are delayed to a future date, which is still not clear. However, seminars, meetings and conferences are necessary for updating our knowledge and skills. Web‐based seminars (webinars) are the solutions to this issue. This study aimed to show the participant behaviour when webinars present at the COVID‐19 pandemic era. Methods: From December 2017 to July 2020, 58 webinars were broadcasted via the Uropedia, electronic library of SUST. Data of all webinars were collected with the YouTube analytics and application of the Uropedia. Data of streaming webinars included participant behaviours such as content views, engagement time, total unique attendees, average engagement time and the number of audience to leads. Data were split into two groups; group‐1 is webinars before COVID‐19 (before March 2020) and group‐2 is the webinars during COVID‐19. Results: Total broadcast time and total page view number were found to be 112.6 hours (6761 minutes) and 15 919, respectively. The median participant age was 40.1 y. Median content view and median engagement time were found to be 261.0 and 12.2 minutes, respectively. Comparison of two groups revealed a significant increment in the content views (group‐1; 134.0 range = 86.0‐87.0 and group‐2; 414.0 range = 296.0‐602.0, P <.001) and the number of the unique attendees (group 1; 18.0 range = 10.0‐26.0 and group‐2; 57.0 range = 27.0‐100.0, P <.001) following COVID‐19. However, the median engagement time of the audience did not seem to change with the COVID‐19 pandemic (group‐1; 11.5 range = 10.0‐13.3 minutes and group‐2; 13.2 range = 9.4‐18.1 minutes, P =.12). Conclusion: The webinars are effective ways to share information and have many advantages, including low cost, reaching a high number of audiences. Audience number and page visits seemed to increase following the COVID‐19 pandemic. However, this era did not seem to affect the critical attitude of the audience, which is engagement time. [ABSTRACT FROM AUTHOR]

Purpose: To compare the functional outcomes of patients who underwent partial (PN) or radical nephrectomy (RN) for clinical T1 (cT1) renal tumours using the Kidney Cancer Database of the Urooncology Association, Turkey. Methods: We retrospectively reviewed 1004 patients who underwent PN and RN for cT1 renal tumours at multiple academic tertiary centres between 2000 and 2018. Patients with preoperative end-stage chronic kidney disease and/or metastatic disease were excluded. Results: There were 452 patients in the PN group and 552 patients in the RN group. The median follow-ups were 74.9 and 83.7 months in RN and PN cohort. The eGFR was significantly reduced in both groups on postoperative day 1 (PN = 13.7 vs RN = 19.1 mL/min/1.73 m2 : P < .001). In the PN group, eGFR showed a tendency to recover according to a quadratic pattern and reached preoperative levels in the first and third years (95.6 ± 28.8 mL/min/1.73 m2 and 96.9 ± 28.9 mL/min/1.73 m2, respectively), with no significant difference between the eGFRs in the 1st and 3rd years (P = .710). To define groups at risk, different cut-off values for the GFR were considered. Among patients with a baseline GFR < 90, the RN cohort had significantly lower eGFRs in the first and third years than the PN cohort (P = .02). Logistic regression showed that comorbidities, coronary artery disease, diabetes and hypertension had no adverse impacts on the changes in the eGFR (P = .60, P = .13, and P = .13, respectively). Conclusion: For the treatment of stage T1 kidney tumours, open or laparoscopic partial nephrectomy has the benefit to preserve renal function. [ABSTRACT FROM AUTHOR]

Objectives: To determine the efficiency of prostate health index (PHI) calculated simultaneously during an ultrasound‐guided fine‐needle prostate biopsy in prostate cancer diagnosis. Methods: The present study included 258 subsequent patients who underwent a TRUS‐guided biopsy in our clinic between August 2015 and March 2016 due to elevated blood levels of PSA and suspicion of prostate cancer. The total PSA, free PSA and pro‐PSA were analysed in all patients before the procedure. Results: The average age of 258 patients was 63.5 (36‐91) years, and the mean PSA level and mean PHI values were 40.1 (0.12‐2170) and 118 (0.41‐1308), respectively. According to the PSA data, the patients were divided into two groups: the low PSA (<4 ng/mL) group containing ten patients with adenocancer (31.2%) and 22 patients with BPH (68.8%) and the high PSA (>4 ng/mL) group consisting of 86 patients with adenocancer (42.2%) and 118 (57.8%) with BPH. The sensitivity and specificity of PSA in detecting prostate adenocancer were calculated as 89.6% and 15.7%, respectively. Similarly, when a PHI level below 55 was accepted as low, and a PHI level at or above 55 was accepted as high, PHI's sensitivity and specificity were determined as 71.9% and 67.9%, respectively. Conclusions: The overall findings indicate that the specificity of PHI is higher than PSA in terms of prostate cancer detection. [ABSTRACT FROM AUTHOR]