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Background and uroses. The 320-detector row CT scanner enables visualization of whole-brain hemodynamic information (dynamic CT angiograhy (CTA) derived from CT erfusion scans). However, arterial image quality in dynamic CTA (dCTA) is inferior to arterial image quality in standard CTA. This study evaluates whether the arterial image quality can be imroved by using a total bolus extraction (ToBE) method. Materials and Methods. DCTAs of 15 atients, who resented with signs of acute cerebral ischemia, were derived from 320-slice CT erfusion scans using both the standard subtraction method and the roosed ToBE method. Two neurointerventionalists blinded to the scan tye scored the arterial image quality on a 5-oint scale in the 4D dCTAs in consensus. Arteries were divided into four categories: (I) large extradural, (II) intradural (large, medium, and small), (III) communicating arteries, and (IV) cerebellar and ohthalmic arteries. Results. Quality of extradural and intradural arteries was significantly higher in the ToBE dCTAs than in the standard dCTAs (extradural = 0.001, large intradural p < 0.001, medium intradural p < 0.001, and small intradural < 0.001). Conclusion. The 4D dCTAs derived with the total bolus extraction (ToBE) method rovide hemodynamic information combined with imroved arterial image quality as comared to standard 4D dCTAs. [ABSTRACT FROM AUTHOR]