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Background and Aim: This is a cross‐sectional observational study conducted on living liver donors focusing on "long‐term remnant liver health" specifically looking at steatosis, inflammation, and fibrosis using multiparametric ultra sonological evaluation and noninvasive blood tests. Methods: Multiparametric ultrasound evaluation included assessment of shear wave elastography (fibrosis), sound speed plane wave ultrasound, attenuation plane wave ultrasound (steatosis), and viscosity plane wave ultrasound (inflammation). Blood test based APRI and FIB‐4 were calculated. Liver biopsy was performed if noninvasive evaluation pointed toward clinically relevant fibro progression (F4). Results: Out of 36 donors, significant fibrosis (>F2) was found in 11 donors (30.5%), seven donors (19.4%) had severe fibrosis (>F3), and two donors had shear wave elastography values suggestive of cirrhosis(F4). Of these two, one donor was extensively evaluated and was found to have biopsy proven cirrhosis with endoscopic evidence of portal hypertension. The prevalence of fatty liver disease in our study group was 50%. Conclusion: We report the first liver donor cohort with fibroprogression and cirrhosis occurring in the remnant liver. Our donor cohort with a significant proportion having steatosis and fibroprogression underscores the importance of regular follow‐up of liver donors and evaluation of remnant liver. [ABSTRACT FROM AUTHOR]

Objectives: To systematically review and evaluate the effects of different types of attachments, implant numbers and loading protocols on the peri-implant mucosa of implant-supported overdentures (ISODs).Background: The impact of peri-implant tissue health on the ISOD treatment outcome is unclear, and current evidence is inadequate on this aspect.Materials and Methods: A systematic literature search for randomised controlled trials or prospective studies was conducted in indexed databases from 1995 to April 2020. The focused question was as follows: How does the peri-implant mucosa respond to implant-supported or implant-tissue-supported complete overdentures based on different types of attachments, implant numbers, and loading protocols, in terms of clinical outcomes achieved [plaque index (PI), gingival index (GI), probing pocket depth (PD) and bleeding index (BI)]? A random- or fixed-effects model was applied to measure the significance of standardised mean differences (SMD) of PD between the groups.Results: Seventeen studies met the eligibility criteria. The SMD for PD between splinted/bar and unsplinted/stud attachments was 0.10 mm (95% CI: -0.27 to 0.47; P = .60) and between 2- and 4-implant groups was 0.15 mm (95% CI: -0.16 to 0.45; P = .34), which were not statistically significant. Significant difference (P = .003) was observed between immediate/early loading and delayed loading (SMD = 0.46 mm [95% CI: 0.16 to 0.75]).Conclusions: Probing depth for the immediate loaded implants was significantly higher than for the delayed loading group. No attachment type, implant number or loading protocol seemed to have a clear advantage over the other, in terms of other peri-implant mucosal outcome measures. [ABSTRACT FROM AUTHOR]

Background: Living donor liver transplantation (LDLT) and donation after circulatory death (DCD) can expand the donor pool for cholestatic liver disease (CLD) patients. We sought to compare the outcomes of deceased donor liver transplant (DDLT) vs LDLT in CLD patients. Methods: Retrospective cohort analysis of adult CLD recipients registered in the OPTN database who received primary LT between 2002 and 2018. Cox proportional hazards regression models with mixed effects were used to determine the impact of graft type on patient and graft survival. Results: Five thousand, nine hundred ninety‐nine DDLT (5730 donation after brain death [DBD], 269 DCD) and 912 LDLT recipients were identified. Ten‐year patient/graft survival rates were DBD: 73.8%/67.9%, DCD: 74.7%/60.7%, and LDLT: 82.5%/73.9%. Higher rates of biliary complications as a cause of graft failure were seen in DCD (56.8%) than LDLT (30.5%) or DBD (18.7%) recipients. On multivariable analysis, graft type was not associated with patient mortality, while DCD was independently associated with graft failure (P =.046). Conclusion: DBD, DCD, and LDLT were associated with comparable overall patient survival. No difference in the risk of graft failure could be observed between LDLT and DBD. DCD can be an acceptable alternative to DBD with equivalent patient survival, but inferior graft survival likely related to the high rate of biliary complications. [ABSTRACT FROM AUTHOR]

The article discusses the Conference on World Mission and Evangelism (CWME), "Moving in the Spirit: Called to Transforming Discipleship," held at 8-13 March 2018 in Arusha, Tanzania. It mentions the conference mission is to join the work of the Holy Spirit; and also mentions discipleship is deemed an overarching theme in mission theology.

Background Echocardiography (echo)-based linear fractional shortening ( FS) is widely used to assess left ventricular dysfunction ( LVdys), but has not been systematically tested for right ventricular dysfunction ( RVdys). Methods The population comprised LVdys patients with and without RVdys ( EF<50%) on cardiac MRI ( CMR): Echo included standard RV indices (fractional area change [ FAC], TAPSE, Sʹ, and FS in parasternal long-axis ( RV outflow tract [ RVOT]) and apical four-chamber views (width [ RVWD], length [ RVLG]). Results A total of 168 patients underwent echo and CMR (3±3 days); FAC (46±9 vs 28±11), TAPSE (1.9±0.4 vs 1.5±0.3), and Sʹ (11.4±2.3 vs 10.0±2.6, all P≤.001) were lower among RVdys patients, as were FS indices ( RVOT 32±8 vs 17±10 | RVWD 40±11 vs 22±12 | RVLG 16±5 vs 9±4%; all P<.001). FS indices yielded similar magnitude of correlation with CMR RVEF ( r=.73-.56) as did FAC ( r=.70), which was slightly higher than TAPSE ( r=.47) and Sʹ ( r=.31; all P<.001). FS indices decreased stepwise vs CMR RVEF tertiles, as did FAC (all P<.001). In multivariate analysis, FS in RVOT (regression coefficient .51 [ CI 0.37-0.65]), RVWD (0.30 [0.19-0.41]), and RVLG (0.45 [0.20-0.71]; all P≤.001) was independently associated with CMR RVEF. FS indices yielded good overall diagnostic performance ( AUC: RVOT 0.89 [ CI 0.82-0.97] | RVWD 0.87 [0.78-0.96] | RVLG 0.80 [0.70-0.90]; all P<.001) for CMR-defined RVdy ( RVEF<50%). Conclusions RV linear FS provides RV functional indices that parallel CMR RVEF. Parasternal long-axis RVOT width, four-chamber RV width, and length are independently associated with RVEF, supporting use of multiple FS indices for RV functional assessment. [ABSTRACT FROM AUTHOR]

Purpose The aim of this research was to evaluate the shear bond strength of different laboratory resin composites bonded to a fiber-reinforced composite substrate with some intermediate adhesive resins. Materials and Methods Mounted test specimens of a bidirectional continuous fiber-reinforced substrate (StickNet) were randomly assigned to three equal groups. Three types of commercially available veneering resin composites - BelleGlass®, Sinfony®, and GC Gradia® were bonded to these specimens using four different adhesive resins. Half the specimens per group were stored for 24 hours; the remaining were stored for 30 days. There were 10 specimens in the test group (n). The shear bond strengths were calculated and expressed in MPa. Data were analyzed statistically, and variations in bond strength within each group were additionally evaluated by calculating the Weibull modulus. Results Shear bond values of those composites are influenced by the different bonding resins and different indirect composites. There was a significant difference in the shear bond strengths using different types of adhesive resins ( p = 0.02) and using different veneering composites ( p < 0.01). Belle-Glass® had the highest mean shear bond strength when bonded to StickNet substrate using both Prime & Bond NT and OptiBond Solo Plus. Sinfony® composite resin exhibited the lowest shear bond strength values when used with the same adhesive resins. The adhesive mode of failure was higher than cohesive with all laboratory composite resins bonded to the StickNet substructure at both storage times. Water storage had a tendency to lower the bond strengths of all laboratory composites, although the statistical differences were not significant. Conclusion Within the limitations of this study, it was found that bonding of the veneering composite to bidirectional continuous fiber-reinforced substrate is influenced by the brand of the adhesive resin and veneering composite. [ABSTRACT FROM AUTHOR]

Billions of birds migrate at night over North America each year. However, few studies have described the phenology of these movements, such as magnitudes, directions, and speeds, for more than one migration season and at regional scales. In this study, we characterize density, direction, and speed of nocturnally migrating birds using data from 13 weather surveillance radars in the autumns of 2010 and 2011 in the northeastern USA. After screening radar data to remove precipitation, we applied a recently developed algorithm for characterizing velocity profiles with previously developed methods to document bird migration. Many hourly radar scans contained windborne 'contamination,' and these scans also exhibited generally low overall reflectivities. Hourly scans dominated by birds showed nightly and seasonal patterns that differed markedly from those of low reflectivity scans. Bird migration occurred during many nights, but a smaller number of nights with large movements of birds defined regional nocturnal migration. Densities varied by date, time, and location but peaked in the second and third deciles of night during the autumn period when the most birds were migrating. Migration track (the direction to which birds moved) shifted within nights from south-southwesterly to southwesterly during the seasonal migration peaks; this shift was not consistent with a similar shift in wind direction. Migration speeds varied within nights, although not closely with wind speed. Airspeeds increased during the night; groundspeeds were highest between the second and third deciles of night, when the greatest density of birds was migrating. Airspeeds and groundspeeds increased during the fall season, although groundspeeds fluctuated considerably with prevailing winds. Significant positive correlations characterized relationships among bird densities at southern coastal radar stations and northern inland radar stations. The quantitative descriptions of broadscale nocturnal migration patterns presented here will be essential for biological and conservation applications. These descriptions help to define migration phenology in time and space, fill knowledge gaps in avian annual cycles, and are useful for monitoring long-term population trends of migrants. Furthermore, these descriptions will aid in assessing potential risks to migrants, particularly from structures with which birds collide and artificial lighting that disorients migrants. [ABSTRACT FROM AUTHOR]

Together towards Life (TTL) and Evangelii Gaudium (EG) convey a renewed and fresh understanding of mission and evangelism that speaks meaningfully to the contemporary context, reminds churches of their primary task of mission and evangelism, and challenges them to reflect on and practice mission and evangelism with joy and life. This essay strives to discuss three important aspects of mission and evangelism that TTL and EG share, albeit with their own distinct perspective. The inseparability of ecclesiology and missiology is one affirmation that is commonly shared by TTL and EG. [ABSTRACT FROM AUTHOR]

Migration is a common strategy used by birds that breed in seasonal environments, and multiple environmental and biological factors determine the timing of migration. How these factors operate in combination during autumn migration, which is considered to be under weaker time constraints relative to spring migration, is not clear., Here, we examine the patterns and determinants of migration timing for nocturnal migrants during autumn migration in the north-eastern USA using nocturnal reflectivity data from 12 weather surveillance radar stations and modelled diurnal probability of occurrence for 142 species of nocturnal migrants. We first model the capacity of seasonal atmospheric conditions (wind and precipitation) and ecological productivity (vegetation greenness) to predict autumn migration intensity. We then test predictions, formulated under optimal migration theory, on how migration timing should be related to assemblage-level estimates of body size and total migration distance within the context of dietary guild (insectivore and omnivore) and level of dietary plasticity during autumn migration., Our results indicate seasonal declines in ecological productivity delineate the beginning and end of peak migration, whose intensity is best predicted by the velocity of winds at migration altitudes. Insectivorous migrants departed earlier in the season and, consistent with our predictions, large-bodied and long-distance insectivorous migrants departed the earliest. Contrary to our predictions, large-bodied and some long-distance omnivorous migrants departed later in the season, patterns that were replicated in part by insectivorous migrants that displayed dietary plasticity during autumn migration., Our findings indicate migration timing in the region is dictated by optimality strategies, modified based on the breadth and flexibility of migrant's foraging diets, with declining ecological productivity defining possible resource thresholds during which migration occurs when winds at migration altitudes are mild. These observations provide the basis to assess how avian migration strategies may be affected by adjustments in seasonal patterns of atmospheric circulation and ecological productivity that may occur under global climate change. [ABSTRACT FROM AUTHOR]

ABSTRACT BACKGROUND AND PURPOSE MRI studies in Parkinson's Disease have shown volumetric reductions of subcortical structures such as the thalamus, putamen, globus pallidus, and caudate nucleus. However, there are no studies which look at the relationship between subcortical structure volumes and clinical variables, such as age and motor severity scores. METHODS Brain MRI scans of 47 consecutive PD patients undergoing deep brain stimulation was acquired. Volumetric data of the thalamus, putamen, caudate nucleus, and globus pallidus were extracted and corrected for total intracranial volume. Pearson correlation coefficient (PCC) and general linear modeling (GLM) were then applied to the volumetric and the clinical variable data to explore the relationships between the two. RESULTS PCC showed a positive correlation between volumes of the left and right thalamus and left and right putamen with increasing duration of disease. GLM demonstrated that duration of symptoms was a significant factor relating to larger left thalamic volume. Male gender was also a significant factor associated with smaller left and right thalamic and right putaminal volumes. CONCLUSIONS There is a correlation between the volume subcortical structures and clinical variables, particularly the disease duration, in PD. This may not only help understanding the disease process but also patient selection for invasive and noninvasive therapies. [ABSTRACT FROM AUTHOR]

The article reports that the World Council of Churches' (WCC) new mission and evangelism statement is about seeking vision, concepts, and directions for a renewed understanding and practice of mission and evangelism in the changing global landscape. Some of the contextual changes that are addressed in the new mission affirmation include the shift of the centre of gravity of global Christianity from global North to global South.

Objectives. This review aims to evaluate the effect of orthodontic therapy on periodontal health. Data. Original articles that reported on the effect of orthodontic therapy on periodontal health were included. The reference lists of potentially relevant review articles were also sought. Sources. A literature search was conducted using the databases, Medline, EMBASE, Cochrane Library, Web of Science, Google Scholar, and Scopus databases for relevant studies. The search was carried out by using a combined text and the MeSH search strategies: using the key words in different combinations: "periodontal disease," "orthodontics" and "root resorption." This was supplemented by hand-searching in peer-reviewed journals and cross-referenced with the articles accessed. Articles published only inEnglish languagewere included. Letters to theEditor, historical reviews and unpublished articleswerenot sought. Conclusions. Within the limitations of the present literature review, it was observed that there is a very close inter-relationship between the periodontal health and the outcome of orthodontic therapy. [ABSTRACT FROM AUTHOR]

The article presents a speech by Metropolitan Geevarghese Coorilos, moderator of the Commission on World Mission and Evangelism, delivered at the 10th Assembly of the World Council of Churches (WCC) on November 1, 2013 in Busan, Korea, in which he discussed the main affirmations of the new WCC Mission and Evangelism statement, the specific accent on mission as spirituality and the most crucial threats to life.

According to the classical Erdős-Pósa theorem, given a positive integer k, every graph G either contains k vertex disjoint cycles or a set of at most [ABSTRACT FROM AUTHOR]

The article examines the theme of the Busan Assembly from a missiological angle, especially from the perspective of 'mission from the margins.' This is done, focussing on Asian contextual realities, with a specific subaltern accent on Indian missiological challenges such as casteism. The article argues that the prayer format of the assembly theme be understood essentially as cries of the marginalized peoples and the exploited nature. Christians and churches are challenged to echo these cries by joining in their struggles to affirm life, justice and peace. Links to the new WCC affirmation on mission and evangelism are also established here. [ABSTRACT FROM AUTHOR]

The article presents a speech by Metropolitan Doctor Geevarghese Mor Coorilos, moderator of the Commission on World Mission and Evangelism (CWME), delivered at the CWME pre-assembly mission event by the World Council of Churches (WCC) in Manila, Philippines, in which he discussed the upcoming WCC assembly in Korea in 2013, the new ecumenical affirmation on mission and evangelism, and the 100th year anniversary of the periodical.

In the face of the environmental crises that threaten all of life, I first review how the WCC focus on creation emerged. I then explore what it would mean for mission theology to turn to God in creation, moving from a dominating to a kenotic 'down to earth' missiology that is rooted in the earthliness of creation, there finding God's grace and healing. This is especially poignant for Dalit and Indigenous People in India who are considered of the earth (mud), and for the tilling and keeping of creation that is our biblical mandate. [ABSTRACT FROM AUTHOR]

Baskaradoss JK, Geevarghese A, Kutty VR. Maternal periodontal status and preterm delivery: a hospital based case-control study. J Periodont Res 2011; 46: 542-549. © 2011 John Wiley & Sons A/S Background and Objective: Recent studies have presented evidence that periodontal disease in pregnant women may be a determining factor for preterm delivery. However, this finding has not been consistently observed. The present investigation was carried out to explore the association between maternal periodontal disease and preterm delivery in the state of Kerala, India. Material and Methods: The case-control study had a sample of 300 (100 cases and 200 controls) postpartum women over 18 years of age. Cases were women who had undergone spontaneous preterm delivery (< 37 wk of gestation) and controls were women who delivered at term (≥ 37 wk of gestation). Standard, clinical and periodontal examinations were performed at the maternity wards, and the existence of an association between periodontal disease and preterm delivery was evaluated by means of a multivariate logistic regression model that also considered other risk factors for preterm delivery. Results: Periodontitis was diagnosed in 25% of the mothers in the case group and in 14.5% of the mothers in the control group. Logistic regression analysis indicated a risk of nearly threefold for preterm delivery in mothers with periodontitis [adjusted odds ratio (ORa) = 2.72; 95% confidence interval (CI): 1.68-6.84]. The other factors significantly associated with preterm birth were physical exertion (ORa = 2.80; 95% CI: 1.18-6.65), a previous history of preterm birth (ORa = 2.65; 95% CI: 1.20-5.83) and previous abortion/death of infant (ORa = 4.08; 95% CI: 1.56-10.65). Conclusion: Periodontal disease is a possible risk factor for preterm delivery in this population. [ABSTRACT FROM AUTHOR]

Studies in our laboratory indicate that collagenase from Clostridium histolyticum promotes endothelial cell and keratinocyte responses to injury in vitro and wound healing in vivo. We postulate that matrix degradation by Clostridial collagenase creates bioactive fragments that can stimulate cellular responses to injury and angiogenesis. To test this hypothesis, we performed limited digestion of defined capillary-endothelial-derived extracellular matrices using purified human or bacterial collagenases. Immunoprecipitation with antibodies recognizing collagens I, II, III, IV, and V, followed by mass spectrometry reveals the presence of unique fragments in bacterial, but not human-enzyme-digested matrix. Results show that there are several bioactive peptides liberated from Clostridial collagenase-treated matrices, which facilitate endothelial responses to injury, and accelerate microvascular remodeling in vitro. Fragments of collagen IV, fibrillin-1, tenascin X, and a novel peptide created by combining specific amino acids contained within fibrillin 1 and tenascin X each have profound proangiogenic properties. The peptides used at 10-100 nM increase rates of microvascular endothelial cell proliferation by up to 47% and in vitro angiogenesis by 200% when compared with serum-stimulated controls. Current studies are aimed at revealing the molecular mechanisms regulating peptide-induced wound healing while extending these in vitro observations using animal modeling. [ABSTRACT FROM AUTHOR]

This article provides a brief history of mission theology of the global church since Edinburgh 1910, highlighting the seismological shifts and major developments in missiological thinking and praxis over the years and through various world mission conferences, specifically from the perspective of the Commission on World Mission and Evangelism (CWME). It argues that, as we prepare ourselves to celebrate the centenary mission conference in Edinburgh in June 2010, mission theology has moved from its early stage of colonial, Eurocentric expressions to post-colonial and polyphonic articulations of missiology. For the CWME, though, the missiological journey continues even beyond 2010. This article argues that, amongst many important missiological themes that CWME needs to address within the overarching theme of 'Ecumenism in Mission', the themes CWME has identified as its major focus for the coming years - viz. ecclesiology and mission, mission as healing, and mission as contestation - are of crucial pertinence. In the changing global Christian landscape where the centre of gravity of Christianity has moved to the global South, and in a context where new forms of being ecclesial communities are tried out, 'The Nature and Mission of the Church' needs to take a 'from below' approach, going beyond the traditional frameworks of mainline churches. Mission as healing would provide a comprehensive and more integral perspective to the salvific purpose of God for this world, especially as 'healing' is a common strand within many religious, ecclesial and spiritual traditions, offering a dialogical perspective. Mission as contestation is equally significant in today's world where the gospel imperative of confronting satanic forces that express themselves in the form of globalization, neo-imperialism, patriarchy, racism, casteism and eco-violence is of cardinal importance. [ABSTRACT FROM AUTHOR]

Iatrogenic perforation of the gallbladder during laparoscopic cholecystectomy is a well-known occurrence; however, the consequences of spillage of gallstones in the peritoneum and particularly intrathoracic complications are less defined. We describe the delayed development of a perihepatic abscess and empyema in a patient five years following laparoscopic cholecystectomy secondary to dropped gallstones. A 53-year-old man with medical history significant for a laparoscopic cholecystectomy five years prior to acute cholecystitis presented with purulent cough, hemoptysis, night sweats, and right-upper quadrant (RUQ) pain. Computed tomography (CT) scan revealed 5.4 cm right-sided subpulmonic and 5.9 cm perihepatic fluid collections with an 8 mm focal radiopaque density within the perihepatic fluid collection. Open intra-abdominal exploration resulted in retrieval of a 1 cm intraperitoneal gallstone. Laparoscopic cholecystectomy is a common surgical operation during which gallstone spillage can occur, causing both intra-abdominal and intrathoracic complications, presenting even years after surgery. This necessitates an attempt to retrieve all free intra-abdominal gallstones during the initial operation. [ABSTRACT FROM AUTHOR]

Provides information on christianity while focusing on the question raised by the theme of the eighth assembly of the World Council of Churches' (WCC). Identification of the theme; Description of the Lord's prayer; What the sequence of the WCC's eighth assembly theme reminds us to do.

Attempts to resolve the question of relation between the ground of hope and many expressions of it in terms of the trinitarian conception of God and his relation to creation. Significance of the unity of humanity in Christ to the goals of society; Nature of Christian faith; Relationship between the Bible, tradition, and hope.

The formation of the micropyle in the oocytes of a gobiid fish O. acutipennis is described. In O. acutipennis the micropyle is formed at the summit of a cone termed here as the ‘micropylar cone’. A single follicular cell takes part in the formation of the micropyle while the two cells on either side seems to play a supporting role in the process. [ABSTRACT FROM AUTHOR]

Transplant surgical workforce concerns have arisen in the last 5 years as reflected in challenges securing job opportunities for new fellows. The present survey was designed by the ASTS Membership and Workforce Committee to describe the current practice characteristics of transplant centers in order to estimate changes in the workforce. The survey questionnaire requested information about the transplant programs, the transplant surgeons involved in the program, and the estimated changes in the staffing of the program over the next 3 years. Seventy‐one transplant centers responded from a total of 235 identified and queried (30.2% response rate), with median responding centers per UNOS region of 7 (IQR 4.5‐8.5). The recruitment outlook for the next 3 years forecasts a positive inflow of surgeons at a 2:1 rate (incoming:leaving). The new female transplant workforce within the responding cohort has increased from 3.7% in 1980 to 18.4% in 2010. Currently, 13.1% of practicing US transplant surgeons in this survey are female which is higher than many other surgical specialties. This report represents the most up‐to‐date view into the abdominal transplant surgical workforce. The positive job recruitment outlook for transplant surgeons and the narrowing gender gap are new findings from this study. [ABSTRACT FROM AUTHOR]

Presents the poem "Holistic God," by Geevarghese Mar Osthathios.