Search

A 7‐month‐old, spayed, female, mixed breed dog was referred for a 3‐day duration of elevated liver enzymes, azotaemia, anorexia and lethargy following ovariohysterectomy. Bloodwork showed non‐regenerative anaemia, inflammatory leukogram, moderate thrombocytopenia, severe azotaemia, severe mixed hepatopathy, hyperbilirubinemia and hypoalbuminemia. Point‐of‐care ultrasound identified free fluid and a heterogeneous mass in the mid‐ventral abdomen. Septic peritonitis was confirmed on cytology, and abdominal exploratory with left medial liver lobectomy was performed. Histopathology identified submassive hepatic necrosis and bridging fibrosis with biliary reaction, confirming a liver lobe torsion. The dog recovered perioperatively, but remained hospitalised to receive dialysis for severe renal dysfunction. The dog was transitioned to outpatient dialysis for several treatments. Unfortunately, kidney function continued to decline after dialysis was discontinued, and humane euthanasia was performed approximately 2 months postoperatively. To the authors' knowledge, this is the first reported case of liver lobe torsion following routine ovariohysterectomy in a dog. [ABSTRACT FROM AUTHOR]

Currently, intraoperative tumour margin imaging is not routinely utilized in veterinary medicine. Optical coherence tomography (OCT) allows for real‐time assessment of tissue morphology of 1–2 mm depth. The aims of this study were (1) to compare the histologic and OCT features of excised canine skin and subcutaneous specimens, and (2) to determine the diagnostic accuracy of OCT for surgical margin evaluation. The authors hypothesized that OCT imaging would correlate well with histopathology and that OCT would be sensitive for detection of incomplete margins. Eighty dogs were prospectively enrolled. Tumours were excised, and the surgical margins were imaged using a spectral domain OCT system. The tumour type and completeness of excision were determined by histopathology. Nine blinded observers received training in OCT image interpretation and were then given a set of OCT images and videos. The observers assigned each image/video a grade from 1 (no tumour) to 4 (tumour) and the results were compared to histopathology. The overall median sensitivity and specificity of OCT imaging for detection of incomplete margins were 86.7% and 84.6%, respectively. A potential limitation is that observers had varied experience with OCT image interpretation, ranging from no prior experience to participating in a previous OCT project. OCT is sensitive for detection of incomplete margins and could be a promising real‐time surgical margin imaging modality. Further study is needed to evaluate intraoperative applications of OCT and its impact on tumour recurrence and long‐term outcome. [ABSTRACT FROM AUTHOR]