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The use of electrochemical methods to study living systems, including cells, has been of interest to researchers for a long time. Thus, controlling the polarization of the electrode contacting living cells, one can influence, for example, their proliferation or the synthesis of specific proteins. Moreover, the electrochemical approach formed the basis of the biocompatibility improvement of the materials contacting with body tissues that use in carbon hemosorbents and implants development. It became possible to reach a fundamentally new level in the study of cell activity with the introduction of optically transparent electrodes in this area. The advantage of the using of optically transparent electrodes is the possibility of simultaneous analysis of living cells by electrochemical and microscopic methods. The use of such materials allowed approaching to the study of the influence of the electrode potential on adhesion activity and morphology of the different cell types (HeLa cells, endothelial cell, etc.) more detailed. There are a negligible number of publications in this area despite the advantages of the usage of optically transparent electrodes to study living cells. This mini‐review is devoted to some aspects of the interaction of living cells with conductive materials and current advances in the use of optically transparent electrodes for the study of living cells, as well as the prospects for their use in cellular technologies. [ABSTRACT FROM AUTHOR]

In this work we used electrochemical methods, open circuit potential (OCP) measurement with platinum electrode, and cyclic voltammetry (CV) in blood serum to assess redox states in patients with polytrauma (n=56) that allow to evaluate probability of survival early on, and therefore have the potential to improve therapy outcomes. Electrochemical assessment of redox states in sera samples correlated with traditional methods of prooxidant/antioxidant balance quantification. OCP and quantity of electricity passed (Q), calculated from CVs, were significantly different between the survivors and non‐survivors. Patients with Q>22 μC (day 1) and OCP>34 mV (day 3) had low chance of survival. [ABSTRACT FROM AUTHOR]