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22 results on '"Coze, Carole"'

3. Rhabdomyosarcoma associated with germline TP53 alteration in children and adolescents: The French experience.

Author

Pondrom, Morgane, Bougeard, Gaelle, Karanian, Marie, Bonneau‐Lagacherie, Jacynthe, Boulanger, Cécile, Boutroux, Hélène, Briandet, Claire, Chevreau, Christine, Corradini, Nadège, Coze, Carole, Defachelles, Anne Sophie, Galmiche‐Roland, Louise, Orbach, Daniel, Piguet, Christophe, Scoazec, Jean Yves, Vérité, Cécile, Willems, Marjolaine, Frebourg, Thierry, Minard, Véronique, and Brugières, Laurence

Published
2020
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4. Treatment of retinoblastoma in Sub-Saharan Africa: Experience of the paediatric oncology unit at Gabriel Toure Teaching Hospital and the Institute of African Tropical Ophthalmology, Bamako, Mali.

Author

Traoré, Fousseyni, Sylla, Fatou, Togo, Boubacar, Kamaté, Bakarou, Diabaté, Konimba, Diakité, Abdoul Aziz, Diall, Hawa, Dicko, Fatoumata, Sylla, Mariam, Bey, Pierre, Desjardins, Laurence, Gagnepain‐Lacheteau, Anne, Coze, Carole, Harif, Mhamed, Doz, François, and Gagnepain-Lacheteau, Anne

Published
2018
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5. Recurrence of Solid Pseudopapillary Neoplasms of the Pancreas: Results of a Nationwide Study of Risk Factors and Treatment Modalities.

Author

Irtan, Sabine, Galmiche‐Rolland, Louise, Elie, Caroline, Orbach, Daniel, Sauvanet, Alain, Elias, Dominique, Guérin, Florent, Coze, Carole, Faure‐Conter, Cécile, Becmeur, François, Demarche, Martine, Galifer, René Benoît, Galloy, Marie Agnès, Podevin, Guillaume, Aubert, Didier, Piolat, Christian, Lagausie, Pascal, and Sarnacki, Sabine

Published
2016
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8. Detection of tumor ALK status in neuroblastoma patients using peripheral blood.

Author

Combaret, Valérie, Iacono, Isabelle, Bellini, Angela, Bréjon, Stéphanie, Bernard, Virginie, Marabelle, Aurélien, Coze, Carole, Pierron, Gaelle, Lapouble, Eve, Schleiermacher, Gudrun, and Blay, Jean Yves

Subjects
TUMOR diagnosis, ANAPLASTIC lymphoma kinase, NEUROBLASTOMA, CRIZOTINIB, DNA, NONINVASIVE diagnostic tests, BLOOD testing, PERIPHERAL circulation
Abstract

New protocols based on ALK-targeted therapy by crizotinib or other ALK-targeting molecules have opened for the treatment of patients with neuroblastoma ( NB) if their tumors showed mutation and/or amplification of the ALK gene. However, tumor samples are not always available for analysis of ALK mutational status in particular at relapse. Here, we evaluated the ALK mutational status of NB samples by analysis of circulating DNA, using the droplet digital PCR (dd PCR) system. dd PCR assays was developed for the detection of ALK mutations at F1174 and R1275 hotspots found in NB tumors and was applied for the analysis of circulating DNA obtained from 200 μL of serum or plasma samples collected from 114 patients with NB. The mutations F1174L (exon 23 position 3520, T>C and position 3522, C>A) and the mutation R1275Q (exon 25 position 3824, G>A) were detected in circulating DNA. The sensitivity of our test was 100%, 85%, and 92%, respectively, and the specificity was 100%, 91%, and 98%, respectively. In conclusion, the assay that we have developed offers a reliable, noninvasive blood test to assess ALK mutational status at F1174 and R1275 hotspots and should help clinicians to identify patients showing an ALK mutation in particular when no tumor tissue is available. [ABSTRACT FROM AUTHOR]

Published
2015
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15. Birth-related characteristics, congenital malformation, maternal reproductive history and neuroblastoma: The ESCALE study (SFCE.

Author

Munzer, Caroline, Menegaux, Florence, Lacour, Brigitte, Valteau-Couanet, Dominique, Michon, Jean, Coze, Carole, Bergeron, Christophe, Auvrignon, Anne, Bernard, Frédéric, Thomas, Caroline, Vannier, Jean-Pierre, Kanold, Justyna, Rubie, Hervé, Hémon, Denis, and Clavel, Jacqueline

Abstract

Since neuroblastoma occurs very early in children's lives, it has been hypothesized that pre- and perinatal factors may play a role in its etiology. This study investigated the role of birth characteristics, congenital malformation and maternal reproductive history in neuroblastoma. The data used were generated by the national population-based case-control study, ESCALE, conducted in France in 2003-2004. The mothers of 191 neuroblastoma cases and 1,681 controls, frequency-matched by age and gender, were interviewed by telephone, using a standardized questionnaire, on several factors including pregnancy, medical history, lifestyle, childhood medical conditions and exposures. A positive association between congenital malformation and all neuroblastoma cases was observed [Odds ratio (OR) = 2.2, 95% confidence interval (95% CI): 1.1-4.5]. Congenital malformations were highly associated to neuroblastoma in children aged less than 1 year (OR = 16.8, 95% CI: 3.1-90), while no association was observed in children aged 1 year or more (OR = 1.0, 95% CI: 0.3-2.9). A negative association with a maternal history of spontaneous abortions was also found (OR = 0.6, 95% CI: 0.4-0.9). The results strongly support the hypothesis that congenital anomalies may be associated with neuroblastoma, particularly in infant (less than 1 year of age). © 2007 Wiley-Liss, Inc. [ABSTRACT FROM AUTHOR]

Published
2008
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