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Summary Contradicting results concerning IOP control and visual field deterioration are presented. Some of these inconsistencies may be due to the statistical method of analysis. Sixty POAG patients with a perimetric follow-up over 3 years were selected. Mean and maximum IOPs were considered during the same period. The patients were divided into two groups according to the IOP control (well controlled or poorly controlled). Visual field progression was defined as a reduction in sensitivity over the fifth percentile in more than four points. Mean IOPs were not significantly different in the group of patients with a visual field deterioration compared to the stable ones, but the percentage of patients with a visual field deterioration was significantly higher in patients with higher IOPs. This holds especially true if IOP below 16 mmHg (G) is considered the ‘target pressure’. IOP reduction seems to play an essential role in visual field progression. In glaucomatous patients, a strict (<16 mmHg (G)) might be necessary. [ABSTRACT FROM AUTHOR]

Evaluates the changes in the morphology of the optic nerve head, retinal fiber layer and visual field in eyes with ocular hypertension or primary open-angle glaucoma (POAG). Examination of the optic disk and retinal nerve fiber layer in patients; Use of topographic image created by the computer; Inclusion and exclusion criteria for enrolment of patients in the study; Consequences of the morphological changes.

Discusses the methods, standardized A-scan echography and computed axial tomography (CAT) used to measure the diameter of the optic nerve thickness and syage of glaucomatous damage. Measurement of the optic nerve diameter in its anterior third retrobulbar tract by echography and CAT; Evidence on the relation between optic nerve diameter reduction and the glaucomatous damage stage; Reliability of the methods.

Reports on the study conducted on advantages of preservative-free ophthalmic preparations in special containers for long-term glaucoma therapy. Association of topical medications for glaucoma therapy with alterations of corneal and conjunctival epithelium; Effect of ophthalmic preservatives on eukaryotic cells; Role of eye drops that are devoid of preservatives; Advantages of monodose containers.

Discusses the results of the study obtained in surgical techniques, deep sclerectomy and viscocanalostomy during the learning curve for open-angle glaucoma treatment. Procedure followed during deep sclerectomy and viscocanalostomy surgical techniques; Problems encountered during the operation; Complications seen in early postoperation period.