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The province of L'Aquila (Central Italy) was marginally affected by COVID‐19 pandemic, but changes in health care seeking behaviors were noticed. The authors retrospectively analyzed de‐identified data concerning all‐cause and cardiovascular hospitalizations, cardiovascular acute phase treatments, and in‐hospital cardiovascular deaths in the province of L'Aquila from January 1 to March 31, in 2020 and 2019. Incidence rate ratios (IRR) comparing 2020 and 2019 for admissions/procedures were calculated through Poisson regression. All‐cause and cardiovascular mortality in the examined time windows was also assessed. Less all‐cause (IRR 0.85, P <.001) and cardiovascular (IRR 0.73, P <.001) hospitalizations occurred in 2020 than in 2019. Less daily cardiovascular procedures were also performed (IRR: 0.74, P =.009). A disproportionate decrease in the number of procedures was observed in relation to cardiovascular hospitalizations in 2020 (−5.5%, P =.001). Unlike all‐cause mortality, more in‐hospital cardiovascular deaths occurred in March 2020 compared with March 2019 (+6.8%, P =.048). [ABSTRACT FROM AUTHOR]