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Protein content and content of some antinutrients were determined in four Vigna unguiculata (L) Walp and three Vicia faba cultivars frequently consumed in Brazil. The V. faba cultivars showed higher protein contents [26.8%–27.2% (w/w)] than the V. unguiculata cultivars [20.5%–22.5% (w/w)]. The difference was, however, not statistically significant ( P ≥ 0.05). Compared with the V. unguiculata cultivars, the V. faba cultivars exhibited a significantly higher content of all antinutritional factors analysed. In V. faba, condensed tannins ranged from 1.95 to 2.87 g eq. catechin (CE) kg−1, polyphenols from 4.81 to 7.21 g kg−1, phytate from 12.7 to 14.3 mmol kg−1, trypsin inhibitor activity from 4.12–4.38 TIU mg−1 and haemagglutinating activity from 51.3 to 57.2 HU kg−1; whereas in V. unguiculata, the corresponding values were determined to be 0.97–1.81 g eq. CE kg−1 for condensed tannins, 5.87–6.62 g kg−1 for polyphenols, 8.7–12.6 mmol kg−1 for phytate, 3.09–3.56 TIU mg−1 for trypsin inhibitor activity and 0.5–0.6 HU kg−1 for haemagglutinating activity. [ABSTRACT FROM AUTHOR]