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1. Triplet Combination of Gemcitabine, Paclitaxel, and Carboplatin Followed by Maintenance 5-Fluorouracil and Folinic Acid in Patients With Metastatic Nasopharyngeal Carcinoma.

Author

Leong, Swan Swan, Wee, Joseph, Rajan, Sandeep, Toh, Chee Keong, Lim, Wan Teck, Hee, Siew Wan, Tay, Miah Hiang, Poon, Donald, and Tan, Eng Huat

Subjects
*NASOPHARYNX cancer, *DRUG therapy, *NEUTROPENIA, *CANCER patients, *ANEMIA, *THROMBOCYTOPENIA
Abstract

The article focuses on the treatment of nasopharyngeal carcinoma (NPC) which is highly reactive to several chemotherapeutic agents. A three-drug combination chemotherapy, which constitutes of gemcitabine, paclitaxel, and carboplatin, was proposed to treat patients with metastatic NPC. In the study of 28 patients, it notes that toxicities generally came from bone marrow suppression including neutropenia, anemia, and thrombocytopenia.

Published
2008
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