1. Association between exposure to air pollution and blood lipids in the general population of Spain.
- Author
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Valdés, Sergio, Doulatram‐Gamgaram, Viyey, Maldonado‐Araque, Cristina, García‐Escobar, Eva, García‐Serrano, Sara, Oualla‐Bachiri, Wasima, García‐Vivanco, Marta, Garrido, Juan Luis, Gil, Victoria, Martín‐Llorente, Fernando, Calle‐Pascual, Alfonso, Castaño, Luis, Delgado, Elías, Menéndez, Edelmiro, Franch‐Nadal, Josep, Gaztambide, Sonia, Girbés, Joan, Chaves, F. Javier, Galán‐García, José L., and Aguilera‐Venegas, Gabriel
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AIR pollution , *BLOOD lipids , *AIR pollutants , *PARTICULATE matter , *AIR quality - Abstract
Background and Aims: We aimed to assess the associations of exposure to air pollutants and standard and advanced lipoprotein measures, in a nationwide sample representative of the adult population of Spain. Methods: We included 4647 adults (>18 years), participants in the national, cross‐sectional, population‐based di@bet.es study, conducted in 2008–2010. Standard lipid measurements were analysed on an Architect C8000 Analyzer (Abbott Laboratories SA). Lipoprotein analysis was made by an advanced 1H‐NMR lipoprotein test (Liposcale®). Participants were assigned air pollution concentrations for particulate matter <10 μm (PM10), <2.5 μm (PM2.5) and nitrogen dioxide (NO2), corresponding to the health examination year, obtained by modelling combined with measurements taken at air quality stations (CHIMERE chemistry‐transport model). Results: In multivariate linear regression models, each IQR increase in PM10, PM2.5 and NO2 was associated with 3.3%, 3.3% and 3% lower levels of HDL‐c and 1.3%, 1.4% and 1.1% lower HDL particle (HDL‐p) concentrations (p <.001 for all associations). In multivariate logistic regression, there was a significant association between PM10, PM2.5 and NO2 concentrations and the odds of presenting low HDL‐c (<40 mg/dL), low HDL‐p (
- Published
- 2024
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