1. Cytomegalovirus serological screening at the first antenatal visit: A tertiary‐centre audit of general practitioner practices and maternal seroprevalence.
- Author
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Rudd, Ignatius Patrick, Marzan, Melvin Barrientos, and Hui, Lisa
- Subjects
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PREVENTION of communicable diseases , *CYTOMEGALOVIRUSES , *MATERNAL health services , *RESEARCH , *SEROPREVALENCE , *CONFIDENCE intervals , *IMMUNOGLOBULINS , *CYTOMEGALOVIRUS diseases , *SERODIAGNOSIS , *MULTIPLE regression analysis , *MEDICAL screening , *RETROSPECTIVE studies , *TERTIARY care , *IMMUNOLOGY technique , *RISK assessment , *T-test (Statistics) , *RESEARCH funding , *SOCIAL classes , *PREGNANCY complications , *PRENATAL care , *ODDS ratio , *DISEASE risk factors , *PREGNANCY - Abstract
Little is published on cytomegalovirus (CMV) serological screening at the first antenatal visit or the contemporary CMV seroprevalence rates among the Australian pregnant population. We performed a retrospective analysis of public hospital births in a major tertiary centre (n = 840) over a two month period. We found that 13.6% (95% confidence interval (CI) 11.4–16.1%) of women had been screened for CMV at their first antenatal visit with their general practitioner. Of these, 43.0% (95% CI 34.3–52.1%) were CMV seronegative and therefore susceptible to primary infection. Seronegative women were also more likely to have been born in an economically developed country, to live in a socio‐economically advantaged postcode and to be nulliparous. The information from this study may help guide future studies of congenital CMV risk reduction strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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