1. Level of Perivascular Inflammation Is Significantly Lower Around the Left Internal Mammary Artery Than Around Native Coronary Arteries
- Author
-
Haruhito Yuki, Thoralf M. Sundt, Takayuki Niida, Keishi Suzuki, Daisuke Kinoshita, Daichi Fujimoto, Damini Dey, Hang Lee, Iris McNulty, Toru Naganuma, Sunao Nakamura, Eisuke Usui, Tsunekazu Kakuta, and Ik‐Kyung Jang
- Subjects
computed tomography angiography ,left internal mammary artery ,optical coherence tomography ,perivascular inflammation ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background The left internal mammary artery (LIMA) is protected from developing atherosclerosis. Perivascular inflammation, which is closely associated with atherosclerosis, can be measured by perivascular adipose tissue attenuation on computed tomography angiography. Whether the absence of atherosclerosis in LIMA is related to the lower level of perivascular inflammation is unknown. This study was performed to compare the level of perivascular inflammation between LIMA in situ and native coronary arteries in patients with coronary artery disease. Methods and Results A total of 573 patients who underwent both computed tomography angiography and optical coherence tomography imaging were included. The level of perivascular adipose tissue attenuation between LIMA in situ and coronary arteries was compared. Perivascular adipose tissue attenuation around LIMA in situ was significantly lower around the 3 coronary arteries (−82.9 [−87.3 to −78.0] versus −70.8 [−75.9 to −65.9]; P
- Published
- 2024
- Full Text
- View/download PDF