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3. Empirical pathological staging and subtyping of TDP‐43 proteinopathies

Author

Young, Alexandra L., primary, Vogel, Jacob W, additional, Robinson, John, additional, McMillan, Corey T, additional, Ossenkoppele, Rik, additional, Wolk, David A., additional, Irwin, David J., additional, Elman, Lauren, additional, Grossman, Murray, additional, Lee, Virginia M‐Y, additional, Lee, Eddie B, additional, Trojanowski, John Q, additional, and Hansson, Oskar, additional

Published
2022
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7. Isolating the Electrocatalytic Activity of a Confined NiFe Motif within Zirconium Phosphate

Author

Sanchez, Joel, primary, Stevens, Michaela Burke, additional, Young, Alexandra R., additional, Gallo, Alessandro, additional, Zhao, Meng, additional, Liu, Yunzhi, additional, Ramos‐Garcés, Mario V., additional, Ben‐Naim, Micha, additional, Colón, Jorge L., additional, Sinclair, Robert, additional, King, Laurie A., additional, Bajdich, Michal, additional, and Jaramillo, Thomas F., additional

Published
2021
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9. Accounting for systematic spatiotemporal variation improves connectome‐based models of tau spreading in human Alzheimer’s disease

Author

Vogel, Jacob W., primary, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Smith, Ruben, additional, Ossenkoppele, Rik, additional, Aksman, Leon M, additional, Strandberg, Olof, additional, La Joie, Renaud, additional, Grothe, Michel J., additional, Rabinovici, Gil D., additional, Alexander, Daniel C., additional, Evans, Alan C., additional, and Hansson, Oskar, additional

Published
2020
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13. Spatiotemporal imaging phenotypes of tau pathology in Alzheimer’s disease

Author

Vogel, Jacob W., primary, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Smith, Ruben, additional, Ossenkoppele, Rik, additional, Aksman, Leon M., additional, Strandberg, Olof, additional, La Joie, Renaud, additional, Grothe, Michel, additional, Medina, Yasser Iturria, additional, Rabinovici, Gil D., additional, Alexander, Daniel C., additional, Evans, Alan C., additional, and Hansson, Oskar, additional

Published
2020
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17. Evolution of white matter damage in amyotrophic lateral sclerosis

Author

Gabel, Matt C., primary, Broad, Rebecca J., additional, Young, Alexandra L., additional, Abrahams, Sharon, additional, Bastin, Mark E., additional, Menke, Ricarda A. L., additional, Al‐Chalabi, Ammar, additional, Goldstein, Laura H., additional, Tsermentseli, Stella, additional, Alexander, Daniel C., additional, Turner, Martin R., additional, Leigh, P. Nigel, additional, and Cercignani, Mara, additional

Published
2020
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23. An image-based model of brain volume biomarker changes in Huntington's disease

Author

Wijeratne, Peter A., primary, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Marinescu, Razvan V., additional, Firth, Nicholas C., additional, Johnson, Eileanoir B., additional, Mohan, Amrita, additional, Sampaio, Cristina, additional, Scahill, Rachael I., additional, Tabrizi, Sarah J., additional, and Alexander, Daniel C., additional

Published
2018
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24. [IC-P-141]: ANALYSIS OF THE HETEROGENEITY OF POSTERIOR CORTICAL ATROPHY: DATA-DRIVEN MODEL PREDICTS DISTINCT ATROPHY PATTERNS FOR THREE DIFFERENT COGNITIVE SUBGROUPS

Author

Marinescu, Razvan Valentin, primary, Primativo, Silvia, additional, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Firth, Nicholas C., additional, Eshaghi, Arman, additional, Garbarino, Sara, additional, Cardoso, Jorge M., additional, Yong, Keir, additional, Fox, Nick C., additional, Lehmann, Manja, additional, Shakespeare, Timothy J., additional, Crutch, Sebastian J., additional, and Alexander, Daniel C., additional

Published
2017
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25. [P4-257]: ANALYSIS OF THE HETEROGENEITY OF POSTERIOR CORTICAL ATROPHY: DATA-DRIVEN MODEL PREDICTS DISTINCT ATROPHY PATTERNS FOR THREE DIFFERENT COGNITIVE SUBGROUPS

Author

Marinescu, Razvan Valentin, primary, Primativo, Silvia, additional, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Firth, Nicholas C., additional, Eshaghi, Arman, additional, Garbarino, Sara, additional, Cardoso, Jorge M., additional, Yong, Keir, additional, Fox, Nick C., additional, Lehmann, Manja, additional, Shakespeare, Timothy J., additional, Crutch, Sebastian J., additional, and Alexander, Daniel C., additional

Published
2017
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28. P1-327: Cross-Sectional Modeling of Regional Perfusion and Gray Matter Volume in Alzheimer's Disease

Author

Bron, Esther E., primary, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Smits, Marion, additional, van Swieten, John C., additional, Wink, Alle Meije, additional, van der Flier, Wiesje M., additional, Barkhof, Frederik, additional, Golay, Xavier, additional, Niessen, Wiro J., additional, Klein, Stefan, additional, and Alexander, Daniel C., additional

Published
2016
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29. P1-009: A Data-Driven Comparison of the Progression of Brain Atrophy in Posterior Cortical Atrophy and Alzheimer's Disease

Author

Marinescu, Razvan Valentin, primary, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Firth, Nicholas C., additional, Lorenzi, Marco, additional, Eshaghi, Arman, additional, Wottschel, Viktor, additional, Cardoso, M. Jorge, additional, Modat, Marc, additional, Yong, Keir, additional, Primativo, Silvia, additional, Fox, Nick C., additional, Lehmann, Manja, additional, Shakespeare, Timothy J., additional, Crutch, Sebastian J., additional, and Alexander, Daniel C., additional

Published
2016
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30. IC-P-106: Cross-Sectional Modeling of Regional Perfusion and Gray Matter Volume in Alzheimer's Disease

Author

Bron, Esther E., primary, Young, Alexandra L., additional, Oxtoby, Neil P., additional, Smits, Marion, additional, van Swieten, John C., additional, Wink, Alle Meije, additional, van der Flier, Wiesje M., additional, Barkhof, Frederik, additional, Golay, Xavier, additional, Niessen, Wiro J., additional, Klein, Stefan, additional, and Alexander, Daniel C., additional

Published
2016
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37. Relative rate of change in cognitive score network dynamics via Bayesian hierarchical models reveal spatial patterns of neurodegeneration.

Author

Cespedes MI, McGree JM, Drovandi CC, Mengersen K, Fripp J, and Doecke JD

Subjects
Atrophy, Bayes Theorem, Brain diagnostic imaging, Brain pathology, Cognition, Humans, Magnetic Resonance Imaging, Alzheimer Disease pathology, Cognitive Dysfunction
Abstract

The degeneration of the human brain is a complex process, which often affects certain brain regions due to healthy aging or disease. This degeneration can be evaluated on regions of interest (ROI) in the brain through probabilistic networks and morphological estimates. Current approaches for finding such networks are limited to analyses at discrete neuropsychological stages, which cannot appropriately account for connectivity dynamics over the onset of cognitive deterioration, and morphological changes are seldom unified with connectivity networks, despite known dependencies. To overcome these limitations, a probabilistic wombling model is proposed to simultaneously estimate ROI cortical thickness and covariance networks contingent on rates of change in cognitive decline. This proposed model was applied to analyze longitudinal data from healthy control (HC) and Alzheimer's disease (AD) groups and found connection differences pertaining to regions, which play a crucial role in lasting cognitive impairment, such as the entorhinal area and temporal regions. Moreover, HC cortical thickness estimates were significantly higher than those in the AD group across all ROIs. The analyses presented in this work will help practitioners jointly analyze brain tissue atrophy at the ROI-level conditional on neuropsychological networks, which could potentially allow for more targeted therapeutic interventions., (© 2020 John Wiley & Sons, Ltd.)

Published
2020
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38. Perspectives on research evidence and clinical practice: a survey of Australian physiotherapists

Author

Leah Nyland, Peter Lekkas, Alexandra Young, Saravana Kumar, Karen Grimmer-Somers, Grimmer, Karen Anne, Lekkas, Peter, Nyland,Leah Jane, Young, Alexandra Frances, and Kumar, Saravana

Subjects
Physical Therapy Specialty, medicine.medical_specialty, barriers, media_common.quotation_subject, Clinical Sciences, Physical Therapy, Sports Therapy and Rehabilitation, Peer support, medicine, Humans, Empowerment, media_common, Research evidence, Response rate (survey), evidence uptake, research, Evidence-Based Medicine, business.industry, Australia, Health services research, Evidence-based medicine, 119999 [FOR], physiotherapists, Logistic Models, Health Care Surveys, Family medicine, Cohort, Other Social Sciences n.e.c, Clinical Competence, Health Services Research, Medical and Health Sciences not elsewhere classified, Factor Analysis, Statistical, business, Knowledge transfer
Abstract

Background and Purpose. Physiotherapists' use of research evidence with clinical decision-making has interested researchers world-wide since 1980; however, little is known about such practices in Australia. The present survey sought information on Australian physiotherapists' perceptions of the importance of research, and barriers to uptake of evidence in clinical practice, when compared with an international cohort from 2001. Method. An Australian-relevant version of an English (UK) National Health Service (NHS) survey instrument was used to canvass 453 physiotherapists, randomly selected from the South Australian Physiotherapy Registration Board 2004–2005 records. The first survey was mailed in August 2005, a reminder was sent two weeks later to non-responders and a follow-up survey was sent in April 2006 to non-responders whose addresses had changed since 2005. Results. There was a 51% response rate. Of the non-responders, 12% were not contactable at their listed address, highlighting the mobility of Australian physiotherapists. Most respondents had undertaken research as students (59.5%) or as students and clinicians (11.5%). Of these, 37.1% were encouraged to embark on more research, and 20.5% were discouraged. The significant predictors of positive perceived importance of research were: previous research experience; being positive about undertaking further research; working in hospitals and holding a postgraduate degree. Clinicians working privately were significantly less likely than managers to be positive about research importance. The only significant predictor for not perceiving barriers to uptake of evidence was being positive about undertaking future research. Conclusions. The study identified constraints on uptake of evidence into practice that were related to accessing, reading and interpreting published research, and implementing findings. Found consistently across employment categories were barriers relating to lack of time, uncertainty about what the research reported, scepticism about the value of research and being isolated from peer support and literature sources. The responses indicated a positive shift towards evidence uptake since the 2001 NHS survey, suggesting an influence of increased exposure to information on evidence-based practice. A greater focus on research whilst training, the application of educational strategies for empowerment, better knowledge transfer and upskilling within the workplace, and ensuring dedicated time and organizational support for research activities are indicated. Copyright © 2007 John Wiley & Sons, Ltd.

Published
2007
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39. Confessions of a Municipal Bond Salesman

Author

Jim Lebenthal, Bernice Kanner, Jim Lebenthal, and Bernice Kanner

Subjects
Municipal bonds--United States, Brokers--United States--Biography
Abstract

A true Wall Street icon tells his story in Confessions of a Municipal Bond Salesman. Follow Jim Lebenthal's life journey from Hollywood reporter to renowned bond salesman in this intriguing book. Each chapter consists of vivid stories in which Lebenthal recounts his successes and setbacks, as he worked to build his family business into one of the best-known municipal bond firms in America. Throughout the book, Lebenthal distills his experiences to help you apply what he's learned to your own careers and life. You'll benefit from Lebenthal's unique advice, as he touches on issues such as recognizing opportunity, ethics and morality at work, the secrets to selling, and avoiding procrastination. Written in an accessible manner and delivered with a dose of Lebenthal's trademark humor, Confessions of a Municipal Bond Salesman offers an entertaining and engaging look at this incredible individual-and shows you how to make the most out of your life.

Published
2006

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