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9 results on '"Wetterling, Friedrich"'

1. Safety and performance of a novel implantable sensor in the inferior vena cava under acute and chronic intravascular volume modulation

Author

Sheridan, William Stephen, primary, Wetterling, Friedrich, additional, Testani, Jeffrey Moore, additional, Borlaug, Barry A., additional, Fudim, Marat, additional, Damman, Kevin, additional, Gray, Alastair, additional, Gaines, Peter, additional, Poloczek, Martin, additional, Madden, Stephen, additional, Tucker, James, additional, Buxo, Teresa, additional, Gaul, Robert, additional, Corcoran, Louise, additional, Sweeney, Fiachra, additional, and Burkhoff, Daniel, additional

Published
2023
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2. Changes in inferior vena cava area represent a more sensitive metric than changes in filling pressures during experimental manipulation of intravascular volume and tone

Author

Ivey‐Miranda, Juan B., primary, Wetterling, Friedrich, additional, Gaul, Robert, additional, Sheridan, Stephen, additional, Asher, Jennifer L., additional, Rao, Veena S., additional, Maulion, Christopher, additional, Mahoney, Devin, additional, Mebazaa, Alexandre, additional, Gray, Alastair P., additional, Burkhoff, Daniel, additional, Cowie, Martin R., additional, Cox, Zachary L., additional, Butler, Javed, additional, Fudim, Marat, additional, McDonald, Kenneth, additional, Damman, Kevin, additional, Borlaug, Barry A., additional, and Testani, Jeffrey M., additional

Published
2022
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3. Impaired reward processing in the human prefrontal cortex distinguishes between persistent and remittent attention deficit hyperactivity disorder

Author

Wetterling, Friedrich, McCarthy, Hazel, Tozzi, Leonardo, Skokauskas, Norbert, O'Doherty, John P., Mulligan, Aisling, Meaney, James, Fagan, Andrew J., Gill, Michael, and Frodl, Thomas

Subjects
mental disorders, behavioral disciplines and activities, psychological phenomena and processes
Abstract

Symptoms of attention deficit hyperactivity disorder (ADHD) in children often persist into adulthood and can lead to severe antisocial behavior. However, to-date it remains unclear whether neuro-functional abnormalities cause ADHD, which in turn can then provide a marker of persistent ADHD. Using event-related functional magnetic resonance imaging (fMRI), we measured blood oxygenation level dependent (BOLD) signal changes in subjects during a reversal learning task in which choice of the correct stimulus led to a probabilistically determined ‘monetary’ reward or punishment. Participants were diagnosed with ADHD during their childhood (N = 32) and were paired with age, gender, and education matched healthy controls (N = 32). Reassessment of the ADHD group as adults resulted in a split between either persistent (persisters, N = 17) or remitted ADHDs (remitters, N = 15). All three groups showed significantly decreased activation in the medial prefrontal cortex (PFC) and the left striatum during punished correct responses, however only remitters and controls presented significant psycho-physiological interaction between these fronto-striatal reward and outcome valence networks. Comparing persisters to remitters and controls showed significantly inverted responses to punishment (P

Published
2015

5. Sodium MRI of the human heart at 7.0 T: preliminary results

Author

Graessl, Andreas, primary, Ruehle, Anjuli, additional, Waiczies, Helmar, additional, Resetar, Ana, additional, Hoffmann, Stefan H., additional, Rieger, Jan, additional, Wetterling, Friedrich, additional, Winter, Lukas, additional, Nagel, Armin M., additional, and Niendorf, Thoralf, additional

Published
2015
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9. Regional and temporal variations in tissue sodium concentration during the acute stroke phase.

Author

Wetterling F, Gallagher L, Macrae IM, Junge S, and Fagan AJ

Subjects
Acute Disease, Analysis of Variance, Animals, Brain Ischemia pathology, Cerebrovascular Circulation, Disease Models, Animal, Image Processing, Computer-Assisted methods, Magnetic Resonance Imaging instrumentation, Male, Rats, Rats, Sprague-Dawley, Stroke pathology, Time Factors, Brain Ischemia metabolism, Magnetic Resonance Imaging methods, Sodium metabolism, Stroke metabolism
Abstract

A technique for noninvasively quantifying the concentration of sodium ((23) Na) ions was applied to the study of ischemic stroke. (23) Na-magnetic resonance imaging techniques have shown considerable potential for measuring subtle changes in ischemic tissue, although studies to date have suffered primarily from poor signal/noise ratio. In this study, accurate quantification of tissue sodium concentration (TSC) was achieved in (23) Na images with voxel sizes of 1.2 μL acquired in 10 min. The evolution of TSC was investigated from 0.5 to 8 h in focal cortical and subcortical ischemic tissue following permanent middle cerebral artery occlusion in the rat (n = 5). Infarct volumes determined from TSC measurements correlated significantly with histology (P = 0.0006). A delayed linear model was fitted to the TSC time course data in each voxel, which revealed that the TSC increase was more immediate (0.2 ± 0.1 h delay time) in subcortical ischemic tissue, whereas it was delayed by 1.6 ± 0.5 h in ischemic cortex (P = 0.0002). No significant differences (P = 0.5) were measured between TSC slope rates in cortical (10.2 ± 1.1 mM/h) and subcortical (9.7 ± 1.1 mM/h) ischemic tissue. The data suggest that any TSC increase measured in ischemic tissue indicates infarction (core) and regions exhibiting a delay to TSC increase indicate potentially salvageable tissue (penumbra)., (Copyright © 2011 Wiley Periodicals, Inc.)

Published
2012
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