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10 results on '"Walz, Christoph"'

1. Analysis of genetic variants of frequently mutated genes in human papillomavirus‐negative primary head and neck squamous cell carcinoma, resection margins, local recurrences and corresponding circulating cell‐free DNA

Author

Flach, Susanne, primary, Kumbrink, Jörg, additional, Walz, Christoph, additional, Hess, Julia, additional, Drexler, Guido, additional, Belka, Claus, additional, Canis, Martin, additional, Jung, Andreas, additional, and Baumeister, Philipp, additional

Published
2022
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2. Digital scoring of EpCAM and slug expression as prognostic markers in head and neck squamous cell carcinomas

Author

Schinke, Henrik, primary, Heider, Theresa, additional, Herkommer, Timm, additional, Simon, Florian, additional, Blancke Soares, Alexandra, additional, Kranz, Gisela, additional, Samaga, Daniel, additional, Dajka, Laura, additional, Feuchtinger, Annette, additional, Walch, Axel, additional, Valeanu, Laura, additional, Walz, Christoph, additional, Kirchner, Thomas, additional, Canis, Martin, additional, Baumeister, Philipp, additional, Belka, Claus, additional, Maihöfer, Cornelius, additional, Marschner, Sebastian, additional, Pflugradt, Ulrike, additional, Ganswindt, Ute, additional, Hess, Julia, additional, Zitzelsberger, Horst, additional, and Gires, Olivier, additional

Published
2020
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3. Cold non‐ischemic heart preservation with continuous perfusion prevents early graft failure in orthotopic pig‐to‐baboon xenotransplantation

Author

Längin, Matthias, primary, Reichart, Bruno, additional, Steen, Stig, additional, Sjöberg, Trygve, additional, Paskevicius, Audrius, additional, Liao, Qiuming, additional, Qin, Guangqi, additional, Mokelke, Maren, additional, Mayr, Tanja, additional, Radan, Julia, additional, Issl, Lara, additional, Buttgereit, Ines, additional, Ying, Jiawei, additional, Fresch, Ann Kathrin, additional, Panelli, Alessandro, additional, Egerer, Stefanie, additional, Bähr, Andrea, additional, Kessler, Barbara, additional, Milusev, Anastasia, additional, Sfriso, Riccardo, additional, Rieben, Robert, additional, Ayares, David, additional, Murray, Peter J., additional, Ellgass, Reinhard, additional, Walz, Christoph, additional, Klymiuk, Nikolai, additional, Wolf, Eckhard, additional, Abicht, Jan‐Michael, additional, and Brenner, Paolo, additional

Published
2020
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4. Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancermetastasis

Author

Bohnenberger, Hanibal, Kaderali, Lars, Stroebel, Philipp, Yepes, Diego, Plessmann, Uwe, Dharia, Neekesh V., Yao, Sha, Heydt, Carina, Merkelbach-Bruse, Sabine, Emmert, Alexander, Hoffmann, Jonatan, Bodemeyer, Julius, Reuter-Jessen, Kirsten, Lois, Anna-Maria, Droege, Leif Hendrik, Baumeister, Philipp, Walz, Christoph, Biggemann, Lorenz, Walter, Roland, Haeupl, Bjoern, Comoglio, Federico, Pan, Kuan-Ting, Scheich, Sebastian, Lenz, Christof, Kueffer, Stefan, Bremmer, Felix, Kitz, Julia, Sitte, Maren, Beissbarth, Tim, Hinterthaner, Marc, Sebastian, Martin, Lotz, Joachim, Schildhaus, Hans-Ulrich, Wolff, Hendrik, Danner, Bernhard C., Brandts, Christian, Buettner, Reinhard, Canis, Martin, Stegmaier, Kimberly, Serve, Hubert, Urlaub, Henning, Oellerich, Thomas, Bohnenberger, Hanibal, Kaderali, Lars, Stroebel, Philipp, Yepes, Diego, Plessmann, Uwe, Dharia, Neekesh V., Yao, Sha, Heydt, Carina, Merkelbach-Bruse, Sabine, Emmert, Alexander, Hoffmann, Jonatan, Bodemeyer, Julius, Reuter-Jessen, Kirsten, Lois, Anna-Maria, Droege, Leif Hendrik, Baumeister, Philipp, Walz, Christoph, Biggemann, Lorenz, Walter, Roland, Haeupl, Bjoern, Comoglio, Federico, Pan, Kuan-Ting, Scheich, Sebastian, Lenz, Christof, Kueffer, Stefan, Bremmer, Felix, Kitz, Julia, Sitte, Maren, Beissbarth, Tim, Hinterthaner, Marc, Sebastian, Martin, Lotz, Joachim, Schildhaus, Hans-Ulrich, Wolff, Hendrik, Danner, Bernhard C., Brandts, Christian, Buettner, Reinhard, Canis, Martin, Stegmaier, Kimberly, Serve, Hubert, Urlaub, Henning, and Oellerich, Thomas

Abstract

Patients with head-and-neck cancer can develop both lung metastasis and primary lung cancer during the course of their disease. Despite the clinical importance of discrimination, reliable diagnostic biomarkers are still lacking. Here, we have characterised a cohort of squamous cell lung (SQCLC) and head-and-neck (HNSCC) carcinomas by quantitative proteomics. In a training cohort, we quantified 4,957 proteins in 44 SQCLC and 30 HNSCC tumours. A total of 518 proteins were found to be differentially expressed between SQCLC and HNSCC, and some of these were identified as genetic dependencies in either of the two tumour types. Using supervised machine learning, we inferred a proteomic signature for the classification of squamous cell carcinomas as either SQCLCor HNSCC, with diagnostic accuracies of 90.5% and 86.8% in cross- and independent validations, respectively. Furthermore, application of this signature to a cohort of pulmonary squamous cell carcinomas of unknown origin leads to a significant prognosticseparation. This study not only provides a diagnostic proteomicsignature for classification of secondary lung tumours in HNSCC patients, but also represents a proteomic resource for HNSCC andSQCLC.

Published
2018

5. CD52 is a molecular target in advanced systemic mastocytosis

Author

Hoermann, Gregor, primary, Blatt, Katharina, additional, Greiner, Georg, additional, Putz, Eva Maria, additional, Berger, Angelika, additional, Herrmann, Harald, additional, Cerny‐Reiterer, Sabine, additional, Gleixner, Karoline V., additional, Walz, Christoph, additional, Hoetzenecker, Konrad, additional, Müllauer, Leonhard, additional, Reiter, Andreas, additional, Sotlar, Karl, additional, Sexl, Veronika, additional, Valent, Peter, additional, and Mayerhofer, Matthias, additional

Published
2014
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8. Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome - a phase-II study

Author

Metzgeroth, Georgia, primary, Walz, Christoph, additional, Erben, Philipp, additional, Popp, Helena, additional, Schmitt-Graeff, Annette, additional, Haferlach, Claudia, additional, Fabarius, Alice, additional, Schnittger, Susanne, additional, Grimwade, David, additional, Cross, Nicholas C. P., additional, Hehlmann, Rüdiger, additional, Hochhaus, Andreas, additional, and Reiter, Andreas, additional

Published
2008
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9. Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2‐PDGFRA fusion gene

Author

Walz, Christoph, primary, Curtis, Claire, additional, Schnittger, Susanne, additional, Schultheis, Beate, additional, Metzgeroth, Georgia, additional, Schoch, Claudia, additional, Lengfelder, Eva, additional, Erben, Philipp, additional, Müller, Martin C., additional, Haferlach, Torsten, additional, Hochhaus, Andreas, additional, Hehlmann, Rüdiger, additional, Cross, Nicholas C. P., additional, and Reiter, Andreas, additional

Published
2006
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10. Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia

Author

Reiter, Andreas, primary, Sauβele, Susanne, additional, Grimwade, David, additional, Wiemels, Joseph L., additional, Segal, Mark R., additional, Lafage‐Pochitaloff, Marina, additional, Walz, Christoph, additional, Weisser, Andreas, additional, Hochhaus, Andreas, additional, Willer, Andreas, additional, Reichert, Anja, additional, Büchner, Thomas, additional, Lengfelder, Eva, additional, Hehlmann, Rüdiger, additional, and Cross, Nicholas C.P., additional

Published
2002
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