1. Development and Validation of Prognostic Indices for Recovery of Physical Functioning Following Stroke: Part 1
- Author
-
Diane Cowper Ripley, Pui L. Kwong, W. Bruce Vogel, Barbara E. Bates, Margaret G. Stineman, Jibby E. Kurichi, Dawei Xie, and Claire Davenport
- Subjects
Male ,medicine.medical_specialty ,Activities of daily living ,medicine.medical_treatment ,Physical Therapy, Sports Therapy and Rehabilitation ,Motor Activity ,Activities of Daily Living ,medicine ,Humans ,Stroke ,Veterans Affairs ,Physical Therapy Modalities ,Aged ,Retrospective Studies ,Aged, 80 and over ,Rehabilitation ,Receiver operating characteristic ,business.industry ,Stroke Rehabilitation ,Retrospective cohort study ,Recovery of Function ,Middle Aged ,Prognosis ,medicine.disease ,Functional Independence Measure ,ROC Curve ,Neurology ,Quartile ,Physical therapy ,Female ,Neurology (clinical) ,business ,Follow-Up Studies - Abstract
Objective To develop a prognostic index using Functional Independence Measure grades and stages that would enable clinicians to determine the likelihood of achieving a level of minimum assistance with physical functioning after a stroke. Grades define varying levels of physical function, and stages define varying levels of cognitive functioning. Design Retrospective cohort study. Setting Veterans Affairs Medical Centers throughout the United States. Participants Veterans with a diagnosis of a new stroke discharged between October 1, 2006, and September 30, 2008, who were below physical grade IV (requiring minimal assistance) at initial rehabilitation assessment. Main Outcome Measure Achievement of physical grade IV or above at final rehabilitation assessment. Results Physical grade IV was reached by 25.8% of participants who were initially below this grade. Seven variables remained independently predictive of physical grade IV after adjustment. These variables were assigned the following points: age, ≤69 years=2, 70-79 years=1, ≥80 years=0; initial physical grade, I=0, II=3, III=4; initial cognitive stage, I or II=0, III=2, IV or V=3, VI or VII=4; absence of renal failure=1; no serious nutritional compromise=3; the type of rehabilitation services received, consultative=0, comprehensive=4; and recovery time between admission and discharge physical grade assessment, 1-2 days=0, 3-7 days=4, and ≥8 days=5. The area under the receiver operating characteristic curve was 0.84 and 0.83 for the point system in the derivation and validation cohorts, respectively. The Hosmer-Lemeshow statistic was not significant ( P = .93) in the derivation cohort, indicating that the regression model demonstrated adequate fit. The proportions of patients recovered to physical grade IV in the first (score ≥9), second (score = 10-12), third (score = 13-15), and fourth (score >15) score quartiles were 2.72%, 11.38%, 28.96%, and 60.34%, respectively. Conclusion By using a simple tool, clinicians can forecast the likelihood of recovery to or above the physical grade IV benchmark by the conclusion of rehabilitation services during the acute stroke hospitalization.
- Published
- 2015